-
1
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
PMID:12297042
-
Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell 2002; 110:673-87; PMID:12297042; http://dx.doi.org/10.1016/S0092-8674(02)00971-6
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
2
-
-
80054765598
-
Overview: Structural biology of integrins
-
PMID:21909908
-
Fu G, Wang W, Luo BH. Overview: structural biology of integrins. Methods Mol Biol 2012; 757:81-99; PMID:21909908; http://dx.doi.org/10.1007/978-1-61779- 166-6-7
-
(2012)
Methods Mol Biol
, vol.757
, pp. 81-99
-
-
Fu, G.1
Wang, W.2
Luo, B.H.3
-
3
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
PMID: 1555235
-
Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992; 69:11-25; PMID: 1555235; http://dx.doi.org/10.1016/0092- 8674(92)90115-S
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
4
-
-
0032894567
-
Signaling through focal adhesion kinase
-
PMID:10354709
-
Schlaepfer DD, Hauck CR, Sieg DJ. Signaling through focal adhesion kinase. Prog Biophys Mol Biol 1999; 71:435-78; PMID:10354709; http://dx.doi.org/10.1016/S0079-6107(98)00052-2
-
(1999)
Prog Biophys Mol Biol
, vol.71
, pp. 435-478
-
-
Schlaepfer, D.D.1
Hauck, C.R.2
Sieg, D.J.3
-
5
-
-
0034658555
-
Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells
-
PMID:10804218
-
Chen LM, Bailey D, Fernandez-Valle C. Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells. J Neurosci 2000; 20:3776-84; PMID:10804218
-
(2000)
J Neurosci
, vol.20
, pp. 3776-3784
-
-
Chen, L.M.1
Bailey, D.2
Fernandez-Valle, C.3
-
6
-
-
0030898418
-
Src family protein tyrosine kinases: Cooperating with growth factor and adhesion signaling pathways
-
PMID:9069259
-
Parsons JT, Parsons SJ. Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr Opin Cell Biol 1997; 9:187-92; PMID:9069259; http://dx.doi.org/10.1016/S0955-0674(97)80062-2
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 187-192
-
-
Parsons, J.T.1
Parsons, S.J.2
-
7
-
-
77951096447
-
Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer
-
PMID:20101634
-
Guan JL. Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer. IUBMB Life 2010; 62:268-76; PMID:20101634
-
(2010)
IUBMB Life
, vol.62
, pp. 268-276
-
-
Guan, J.L.1
-
8
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
PMID:16919435
-
Mitra SK, Schlaepfer DD. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol 2006; 18:516-23; PMID:16919435; http://dx.doi.org/10.1016/j.ceb.2006.08.011
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 516-523
-
-
Mitra, S.K.1
Schlaepfer, D.D.2
-
9
-
-
0030026679
-
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase
-
PMID:8538749
-
Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, et al. Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase. Nature 1996; 379:91-6; PMID:8538749; http://dx.doi.org/10.1038/379091a0
-
(1996)
Nature
, vol.379
, pp. 91-96
-
-
Hannigan, G.E.1
Leung-Hagesteijn, C.2
Fitz-Gibbon, L.3
Coppolino, M.G.4
Radeva, G.5
Filmus, J.6
-
10
-
-
80055062698
-
Integrin-linked kinase: Not so 'pseudo' after all
-
PMID:21602880
-
Hannigan GE, McDonald PC, Walsh MP, Dedhar S. Integrin-linked kinase: not so 'pseudo' after all. Oncogene 2011; 30:4375-85; PMID:21602880; http://dx.doi.org/10.1038/onc.2011.177
-
(2011)
Oncogene
, vol.30
, pp. 4375-4385
-
-
Hannigan, G.E.1
McDonald, P.C.2
Walsh, M.P.3
Dedhar, S.4
-
11
-
-
0033379103
-
Integrin-linked kinase and PINCH: Partners in regulation of cell-extracellular matrix interaction and signal transduction
-
PMID:10574698
-
Wu C. Integrin-linked kinase and PINCH: partners in regulation of cell-extracellular matrix interaction and signal transduction. J Cell Sci 1999; 112:4485-9; PMID:10574698
-
(1999)
J Cell Sci
, vol.112
, pp. 4485-4489
-
-
Wu, C.1
-
12
-
-
0033020670
-
The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells
-
PMID:10022929
-
Tu Y, Li F, Goicoechea S, Wu C. The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells. Mol Cell Biol 1999; 19:2425-34; PMID:10022929
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2425-2434
-
-
Tu, Y.1
Li, F.2
Goicoechea, S.3
Wu, C.4
-
13
-
-
78649474761
-
Integrin signalling adaptors: Not only figurants in the cancer story
-
PMID:21102636
-
Cabodi S, del Pilar Camacho-Leal M, Di Stefano P, Defilippi P. Integrin signalling adaptors: not only figurants in the cancer story. Nat Rev Cancer 2010; 10:858-70; PMID:21102636; http://dx.doi.org/10.1038/nrc2967
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 858-870
-
-
Cabodi, S.1
Del Pilar Camacho-Leal, M.2
Di Stefano, P.3
Defilippi, P.4
-
14
-
-
70849099495
-
The extracellular matrix: Not just pretty fibrils
-
PMID:19965464
-
Hynes RO. The extracellular matrix: not just pretty fibrils. Science 2009; 326:1216-9; PMID:19965464; http://dx.doi.org/10.1126/science.1176009
-
(2009)
Science
, vol.326
, pp. 1216-1219
-
-
Hynes, R.O.1
-
15
-
-
62449175839
-
Interactions between extracellular matrix and growth factors in wound healing
-
PMID:19320882
-
Schultz GS, Wysocki A. Interactions between extracellular matrix and growth factors in wound healing. Wound Repair Regen 2009; 17:153-62; PMID:19320882; http://dx.doi.org/10.1111/j.1524-475X.2009.00466.x
-
(2009)
Wound Repair Regen
, vol.17
, pp. 153-162
-
-
Schultz, G.S.1
Wysocki, A.2
-
16
-
-
84863862833
-
Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression
-
PMID:20980442
-
Schedin P, Keely PJ. Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression. Cold Spring Harb Perspect Biol 2011; 3:a003228; PMID:20980442; http://dx.doi.org/10.1101/ cshperspect.a003228
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
-
-
Schedin, P.1
Keely, P.J.2
-
17
-
-
84863872233
-
Cell-extracellular matrix interactions in normal and diseased skin
-
PMID:21441589
-
Watt FM, Fujiwara H. Cell-extracellular matrix interactions in normal and diseased skin. Cold Spring Harb Perspect Biol 2011; 3:a005124; PMID:21441589; http://dx.doi.org/10.1101/cshperspect.a005124
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
-
-
Watt, F.M.1
Fujiwara, H.2
-
18
-
-
0035315836
-
Synthesis and degradation of basement membranes and extracellular matrix and their regulation by TGF-beta in invasive carcinomas
-
(Review). [Review] PMID:11251160
-
Hagedorn HG, Bachmeier BE, Nerlich AG. Synthesis and degradation of basement membranes and extracellular matrix and their regulation by TGF-beta in invasive carcinomas (Review). [Review]. Int J Oncol 2001; 18:669-81; PMID:11251160
-
(2001)
Int J Oncol
, vol.18
, pp. 669-681
-
-
Hagedorn, H.G.1
Bachmeier, B.E.2
Nerlich, A.G.3
-
19
-
-
79959826381
-
Extracellular matrix dynamics in hepatocarcinogenesis: A comparative proteomics study of PDGFC transgenic and Pten null mouse models
-
PMID:21731504
-
Lai KK, Shang S, Lohia N, Booth GC, Masse DJ, Fausto N, et al. Extracellular matrix dynamics in hepatocarcinogenesis: a comparative proteomics study of PDGFC transgenic and Pten null mouse models. PLoS Genet 2011; 7:e1002147; PMID:21731504; http://dx.doi.org/10.1371/journal.pgen.1002147
-
(2011)
PLoS Genet
, vol.7
-
-
Lai, K.K.1
Shang, S.2
Lohia, N.3
Booth, G.C.4
Masse, D.J.5
Fausto, N.6
-
20
-
-
0029312252
-
Involvement of extracellular matrix constituents in breast cancer
-
PMID:7495985
-
Lochter A, Bissell MJ. Involvement of extracellular matrix constituents in breast cancer. Semin Cancer Biol 1995; 6:165-73; PMID:7495985; http://dx.doi.org/10.1006/scbi.1995.0017
-
(1995)
Semin Cancer Biol
, vol.6
, pp. 165-173
-
-
Lochter, A.1
Bissell, M.J.2
-
21
-
-
0032602059
-
Cell-cell and cell-matrix interactions during breast cancer progression
-
PMID: 10339911
-
Noel A, Kebers F, Maquoi E, Foidart JM. Cell-cell and cell-matrix interactions during breast cancer progression. Curr Top Pathol 1999; 93:183-93; PMID: 10339911; http://dx.doi.org/10.1007/978-3-642-58456-5-19
-
(1999)
Curr Top Pathol
, vol.93
, pp. 183-193
-
-
Noel, A.1
Kebers, F.2
Maquoi, E.3
Foidart, J.M.4
-
22
-
-
0031735179
-
Changes in matrix composition during the growth and regression of human hemangiomas
-
PMID:9790808
-
Jang YC, Arumugam S, Ferguson M, Gibran NS, Isik FF. Changes in matrix composition during the growth and regression of human hemangiomas. J Surg Res 1998; 80:9-15; PMID:9790808; http://dx.doi.org/10.1006/jsre.1998.5355
-
(1998)
J Surg Res
, vol.80
, pp. 9-15
-
-
Jang, Y.C.1
Arumugam, S.2
Ferguson, M.3
Gibran, N.S.4
Isik, F.F.5
-
23
-
-
0030793621
-
The basement membrane and tumor progression in the uterine cervix
-
PMID:9228252
-
Nair SA, Nair MB, Jayaprakash PG, Rajalekshmy TN, Nair MK, Pillai MR. The basement membrane and tumor progression in the uterine cervix. Gen Diagn Pathol 1997; 142:297-303; PMID:9228252
-
(1997)
Gen Diagn Pathol
, vol.142
, pp. 297-303
-
-
Nair, S.A.1
Nair, M.B.2
Jayaprakash, P.G.3
Rajalekshmy, T.N.4
Nair, M.K.5
Pillai, M.R.6
-
24
-
-
0027993307
-
Increased tenascin expression in melanocytic tumors
-
PMID:7532653
-
Tuominen H, Kallioinen M. Increased tenascin expression in melanocytic tumors. J Cutan Pathol 1994; 21:424-9; PMID:7532653; http://dx.doi.org/10.1111/ j.1600-0560.1994.tb00284.x
-
(1994)
J Cutan Pathol
, vol.21
, pp. 424-429
-
-
Tuominen, H.1
Kallioinen, M.2
-
25
-
-
0032473476
-
Tenascin-C matrix assembly in oral squamous cell carcinoma
-
PMID: 9495234
-
Ramos DM, Chen B, Regezi J, Zardi L, Pytela R. Tenascin-C matrix assembly in oral squamous cell carcinoma. Int J Cancer 1998; 75:680-7; PMID: 9495234; http://dx.doi.org/10.1002/(SICI)1097-0215(19980302)75:5<680::AID-IJC4>3.0. CO;2-V
-
(1998)
Int J Cancer
, vol.75
, pp. 680-687
-
-
Ramos, D.M.1
Chen, B.2
Regezi, J.3
Zardi, L.4
Pytela, R.5
-
26
-
-
0032904304
-
Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis
-
PMID:10334190
-
Zeng ZS, Cohen AM, Guillem JG. Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis. Carcinogenesis 1999; 20:749-55; PMID:10334190; http://dx.doi.org/10.1093/carcin/20.5.749
-
(1999)
Carcinogenesis
, vol.20
, pp. 749-755
-
-
Zeng, Z.S.1
Cohen, A.M.2
Guillem, J.G.3
-
27
-
-
0028246649
-
Alterations in expression of basement membrane proteins during tumour progression in oral mucosa
-
PMID:8063281
-
Kannan S, Balaram P, Chandran GJ, Pillai MR, Mathew B, Nalinakumari KR, et al. Alterations in expression of basement membrane proteins during tumour progression in oral mucosa. Histopathology 1994; 24:531-7; PMID:8063281; http://dx.doi.org/10.1111/j.1365-2559.1994.tb00571.x
-
(1994)
Histopathology
, vol.24
, pp. 531-537
-
-
Kannan, S.1
Balaram, P.2
Chandran, G.J.3
Pillai, M.R.4
Mathew, B.5
Nalinakumari, K.R.6
-
28
-
-
0031690976
-
Loss of basement membrane components laminin and type IV collagen parallels the progression of oral epithelial neoplasia
-
PMID: 9777393
-
Tosios KI, Kapranos N, Papanicolaou SI. Loss of basement membrane components laminin and type IV collagen parallels the progression of oral epithelial neoplasia. Histopathology 1998; 33:261-8; PMID: 9777393; http://dx.doi.org/10.1046/j.1365-2559.1998.00452.x
-
(1998)
Histopathology
, vol.33
, pp. 261-268
-
-
Tosios, K.I.1
Kapranos, N.2
Papanicolaou, S.I.3
-
29
-
-
0032798869
-
Fibronectin in human prostatic cells in vivo and in vitro: Expression, distribution, and pathological significance
-
PMID:10461812
-
Albrecht M, Renneberg H, Wennemuth G, Möschler O, Janssen M, Aumüller G, et al. Fibronectin in human prostatic cells in vivo and in vitro: expression, distribution, and pathological significance. Histochem Cell Biol 1999; 112:51-61; PMID:10461812; http://dx.doi.org/10.1007/s004180050391
-
(1999)
Histochem Cell Biol
, vol.112
, pp. 51-61
-
-
Albrecht, M.1
Renneberg, H.2
Wennemuth, G.3
Möschler, O.4
Janssen, M.5
Aumüller, G.6
-
30
-
-
0029024897
-
Expression of hemidesmosomal and extracellular matrix proteins by normal and malignant human prostate tissue
-
PMID:7778688
-
Nagle RB, Hao J, Knox JD, Dalkin BL, Clark V, Cress AE. Expression of hemidesmosomal and extracellular matrix proteins by normal and malignant human prostate tissue. Am J Pathol 1995; 146:1498-507; PMID:7778688
-
(1995)
Am J Pathol
, vol.146
, pp. 1498-1507
-
-
Nagle, R.B.1
Hao, J.2
Knox, J.D.3
Dalkin, B.L.4
Clark, V.5
Cress, A.E.6
-
31
-
-
3242788189
-
Role of the extracellular matrix in prostate carcinogenesis
-
PMID: 14689579
-
Nagle RB. Role of the extracellular matrix in prostate carcinogenesis. J Cell Biochem 2004; 91:36-40; PMID: 14689579; http://dx.doi.org/10.1002/jcb.10692
-
(2004)
J Cell Biochem
, vol.91
, pp. 36-40
-
-
Nagle, R.B.1
-
32
-
-
0028200873
-
Differential expression of extracellular matrix molecules and the alpha 6-integrins in the normal and neoplastic prostate
-
PMID:8030747
-
Knox JD, Cress AE, Clark V, Manriquez L, Affinito KS, Dalkin BL, et al. Differential expression of extracellular matrix molecules and the alpha 6-integrins in the normal and neoplastic prostate. Am J Pathol 1994; 145:167-74; PMID:8030747
-
(1994)
Am J Pathol
, vol.145
, pp. 167-174
-
-
Knox, J.D.1
Cress, A.E.2
Clark, V.3
Manriquez, L.4
Affinito, K.S.5
Dalkin, B.L.6
-
33
-
-
0028973409
-
The alpha 6 beta 1 and alpha 6 beta 4 integrins in human prostate cancer progression
-
PMID:8548870
-
Cress AE, Rabinovitz I, Zhu W, Nagle RB. The alpha 6 beta 1 and alpha 6 beta 4 integrins in human prostate cancer progression. Cancer Metastasis Rev 1995; 14:219-28; PMID:8548870; http://dx.doi.org/10.1007/BF00690293
-
(1995)
Cancer Metastasis Rev
, vol.14
, pp. 219-228
-
-
Cress, A.E.1
Rabinovitz, I.2
Zhu, W.3
Nagle, R.B.4
-
34
-
-
0030888322
-
Co-ordinated changes in expression of cell adhesion molecules in prostate cancer
-
PMID:9135498
-
Murant SJ, Handley J, Stower M, Reid N, Cussenot O, Maitland NJ. Co-ordinated changes in expression of cell adhesion molecules in prostate cancer. Eur J Cancer 1997; 33:263-71; PMID:9135498; http://dx.doi.org/10.1016/ S0959-8049(96)00418-2
-
(1997)
Eur J Cancer
, vol.33
, pp. 263-271
-
-
Murant, S.J.1
Handley, J.2
Stower, M.3
Reid, N.4
Cussenot, O.5
Maitland, N.J.6
-
35
-
-
77955944482
-
Association between integrin expression and prognosis in localized prostate cancer
-
PMID: 20564421
-
Pontes-Júnior J, Reis ST, de Oliveira LC, Sant'anna AC, Dall'oglio MF, Antunes AA, et al. Association between integrin expression and prognosis in localized prostate cancer. Prostate 2010; 70:1189-95; PMID: 20564421; http://dx.doi.org/10.1002/pros.21153
-
(2010)
Prostate
, vol.70
, pp. 1189-1195
-
-
Pontes Jr., J.1
Reis, S.T.2
De Oliveira, L.C.3
Sant'Anna, A.C.4
Dall'Oglio, M.F.5
Antunes, A.A.6
-
36
-
-
0027245106
-
Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines
-
PMID:7688749
-
Witkowski CM, Rabinovitz I, Nagle RB, Affinito KS, Cress AE. Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines. J Cancer Res Clin Oncol 1993; 119:637-44; PMID:7688749; http://dx.doi.org/10.1007/BF01215981
-
(1993)
J Cancer Res Clin Oncol
, vol.119
, pp. 637-644
-
-
Witkowski, C.M.1
Rabinovitz, I.2
Nagle, R.B.3
Affinito, K.S.4
Cress, A.E.5
-
37
-
-
80054972160
-
3D tumour models: Novel in vitro approaches to cancer studies
-
PMID:21499821
-
Nyga A, Cheema U, Loizidou M. 3D tumour models: novel in vitro approaches to cancer studies. J Cell Commun Signal 2011; 5:239-48; PMID:21499821; http://dx.doi.org/10.1007/s12079-011-0132-4
-
(2011)
J Cell Commun Signal
, vol.5
, pp. 239-248
-
-
Nyga, A.1
Cheema, U.2
Loizidou, M.3
-
38
-
-
34247864012
-
Three-dimensional culture models of normal and malignant breast epithelial cells
-
PMID:17396127
-
Lee GY, Kenny PA, Lee EH, Bissell MJ. Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods 2007; 4:359-65; PMID:17396127; http://dx.doi.org/10.1038/nmeth1015
-
(2007)
Nat Methods
, vol.4
, pp. 359-365
-
-
Lee, G.Y.1
Kenny, P.A.2
Lee, E.H.3
Bissell, M.J.4
-
39
-
-
84856015401
-
β1 integrin is required for anchorage-independent growth and invasion of tumor cells in a context dependent manner
-
PMID:22099877
-
Schooley AM, Andrews NM, Zhao H, Addison CL. β1 integrin is required for anchorage-independent growth and invasion of tumor cells in a context dependent manner. Cancer Lett 2012; 316:157-67; PMID:22099877; http://dx.doi.org/10.1016/j.canlet.2011.10.032
-
(2012)
Cancer Lett
, vol.316
, pp. 157-167
-
-
Schooley, A.M.1
Andrews, N.M.2
Zhao, H.3
Addison, C.L.4
-
40
-
-
77952506397
-
Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1
-
PMID:20333644
-
Goel HL, Underwood JM, Nickerson JA, Hsieh CC, Languino LR. Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1. J Cell Physiol 2010; 224:210-7; PMID:20333644
-
(2010)
J Cell Physiol
, vol.224
, pp. 210-217
-
-
Goel, H.L.1
Underwood, J.M.2
Nickerson, J.A.3
Hsieh, C.C.4
Languino, L.R.5
-
41
-
-
72449160313
-
Selective and uncoupled role of substrate elasticity in the regulation of replication and transcription in epithelial cells
-
PMID:20016064
-
Kocgozlu L, Lavalle P, Koenig G, Senger B, Haikel Y, Schaaf P, et al. Selective and uncoupled role of substrate elasticity in the regulation of replication and transcription in epithelial cells. J Cell Sci 2010; 123:29-39; PMID:20016064; http://dx.doi.org/10.1242/jcs.053520
-
(2010)
J Cell Sci
, vol.123
, pp. 29-39
-
-
Kocgozlu, L.1
Lavalle, P.2
Koenig, G.3
Senger, B.4
Haikel, Y.5
Schaaf, P.6
-
42
-
-
77956123956
-
Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture
-
PMID:20647425
-
Gilbert PM, Havenstrite KL, Magnusson KE, Sacco A, Leonardi NA, Kraft P, et al. Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Science 2010; 329:1078-81; PMID:20647425; http://dx.doi.org/10.1126/ science.1191035
-
(2010)
Science
, vol.329
, pp. 1078-1081
-
-
Gilbert, P.M.1
Havenstrite, K.L.2
Magnusson, K.E.3
Sacco, A.4
Leonardi, N.A.5
Kraft, P.6
-
43
-
-
77957940500
-
Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells
-
PMID:20890282
-
Holst J, Watson S, Lord MS, Eamegdool SS, Bax DV, Nivison-Smith LB, et al. Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nat Biotechnol 2010; 28:1123-8; PMID:20890282; http://dx.doi.org/10.1038/nbt.1687
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1123-1128
-
-
Holst, J.1
Watson, S.2
Lord, M.S.3
Eamegdool, S.S.4
Bax, D.V.5
Nivison-Smith, L.B.6
-
44
-
-
79959345857
-
Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity
-
PMID:21593411
-
Du J, Chen X, Liang X, Zhang G, Xu J, He L, et al. Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity. Proc Natl Acad Sci U S A 2011; 108:9466-71; PMID:21593411; http://dx.doi.org/10.1073/pnas.1106467108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9466-9471
-
-
Du, J.1
Chen, X.2
Liang, X.3
Zhang, G.4
Xu, J.5
He, L.6
-
45
-
-
57349157913
-
Mechanosensing machinery for cells under low substratum rigidity
-
PMID:18923058
-
Wei WC, Lin HH, Shen MR, Tang MJ. Mechanosensing machinery for cells under low substratum rigidity. Am J Physiol Cell Physiol 2008; 295:C1579-89; PMID:18923058; http://dx.doi.org/10.1152/ajpcell.00223.2008
-
(2008)
Am J Physiol Cell Physiol
, vol.295
-
-
Wei, W.C.1
Lin, H.H.2
Shen, M.R.3
Tang, M.J.4
-
46
-
-
5144235557
-
Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
-
PMID:15324699
-
White DE, Kurpios NA, Zuo D, Hassell JA, Blaess S, Mueller U, et al. Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 2004; 6:159-70; PMID:15324699; http://dx.doi.org/10.1016/j.ccr.2004.06.025
-
(2004)
Cancer Cell
, vol.6
, pp. 159-170
-
-
White, D.E.1
Kurpios, N.A.2
Zuo, D.3
Hassell, J.A.4
Blaess, S.5
Mueller, U.6
-
47
-
-
38049098089
-
Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
-
PMID:18056629
-
Lahlou H, Sanguin-Gendreau V, Zuo D, Cardiff RD, McLean GW, Frame MC, et al. Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proc Natl Acad Sci U S A 2007; 104:20302-7; PMID:18056629; http://dx.doi.org/10.1073/pnas.0710091104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20302-20307
-
-
Lahlou, H.1
Sanguin-Gendreau, V.2
Zuo, D.3
Cardiff, R.D.4
McLean, G.W.5
Frame, M.C.6
-
48
-
-
77957283664
-
Beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression
-
PMID:20713705
-
Huck L, Pontier SM, Zuo DM, Muller WJ. beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression. Proc Natl Acad Sci U S A 2010; 107:15559-64; PMID:20713705; http://dx.doi.org/10.1073/pnas.1003034107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15559-15564
-
-
Huck, L.1
Pontier, S.M.2
Zuo, D.M.3
Muller, W.J.4
-
49
-
-
36849080314
-
Matrix metalloproteinases at cancer tumor-host interface
-
PMID:17625931
-
Noël A, Jost M, Maquoi E. Matrix metalloproteinases at cancer tumor-host interface. Semin Cell Dev Biol 2008; 19:52-60; PMID:17625931; http://dx.doi.org/10.1016/j.semcdb.2007.05.011
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 52-60
-
-
Noël, A.1
Jost, M.2
Maquoi, E.3
-
50
-
-
77956301181
-
Matrix metallo-proteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion
-
PMID:20470890
-
Bourboulia D, Stetler-Stevenson WG. Matrix metallo-proteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion. Semin Cancer Biol 2010; 20:161-8; PMID:20470890; http://dx.doi.org/10.1016/j.semcancer.2010.05.002
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 161-168
-
-
Bourboulia, D.1
Stetler-Stevenson, W.G.2
-
51
-
-
45849098735
-
The role of tissue inhibitors of metalloproteinases in tumorigenesis and metastasis
-
PMID:18568853
-
Cruz-Munoz W, Khokha R. The role of tissue inhibitors of metalloproteinases in tumorigenesis and metastasis. Crit Rev Clin Lab Sci 2008; 45:291-338; PMID:18568853; http://dx.doi.org/10.1080/10408360801973244
-
(2008)
Crit Rev Clin Lab Sci
, vol.45
, pp. 291-338
-
-
Cruz-Munoz, W.1
Khokha, R.2
-
52
-
-
78751571123
-
Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity
-
PMID:20821288
-
Maity G, Choudhury PR, Sen T, Ganguly KK, Sil H, Chatterjee A. Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity. Tumour Biol 2011; 32:129-38; PMID:20821288; http://dx.doi.org/10.1007/s13277-010-0106-9
-
(2011)
Tumour Biol
, vol.32
, pp. 129-138
-
-
Maity, G.1
Choudhury, P.R.2
Sen, T.3
Ganguly, K.K.4
Sil, H.5
Chatterjee, A.6
-
53
-
-
77957155028
-
Fibronectin induces matrix metalloproteinase-9 (MMP-9) in human laryngeal carcinoma cells by involving multiple signaling pathways
-
PMID:20638438
-
Sen T, Dutta A, Maity G, Chatterjee A. Fibronectin induces matrix metalloproteinase-9 (MMP-9) in human laryngeal carcinoma cells by involving multiple signaling pathways. Biochimie 2010; 92:1422-34; PMID:20638438; http://dx.doi.org/10.1016/j.biochi.2010.07.005
-
(2010)
Biochimie
, vol.92
, pp. 1422-1434
-
-
Sen, T.1
Dutta, A.2
Maity, G.3
Chatterjee, A.4
-
54
-
-
0032883939
-
Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines. A process repressed through RAS/MAP kinase signaling pathways
-
PMID: 10515879
-
Esparza J, Vilardell C, Calvo J, Juan M, Vives J, Urbano-Márquez A, et al. Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines. A process repressed through RAS/MAP kinase signaling pathways. Blood 1999; 94:2754-66; PMID: 10515879
-
(1999)
Blood
, vol.94
, pp. 2754-2766
-
-
Esparza, J.1
Vilardell, C.2
Calvo, J.3
Juan, M.4
Vives, J.5
Urbano-Márquez, A.6
-
55
-
-
3242676769
-
Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C
-
PMID:15249664
-
Dechow TN, Pedranzini L, Leitch A, Leslie K, Gerald WL, Linkov I, et al. Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C. Proc Natl Acad Sci U S A 2004; 101:10602-7; PMID:15249664; http://dx.doi.org/10.1073/pnas.0404100101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10602-10607
-
-
Dechow, T.N.1
Pedranzini, L.2
Leitch, A.3
Leslie, K.4
Gerald, W.L.5
Linkov, I.6
-
56
-
-
0346365371
-
Integrin alpha1beta1 and alpha2beta1 are the key regulators of hepatocarcinoma cell invasion across the fibrotic matrix microenvironment
-
PMID:14678990
-
Yang C, Zeisberg M, Lively JC, Nyberg P, Afdhal N, Kalluri R. Integrin alpha1beta1 and alpha2beta1 are the key regulators of hepatocarcinoma cell invasion across the fibrotic matrix microenvironment. Cancer Res 2003; 63:8312-7; PMID:14678990
-
(2003)
Cancer Res
, vol.63
, pp. 8312-8317
-
-
Yang, C.1
Zeisberg, M.2
Lively, J.C.3
Nyberg, P.4
Afdhal, N.5
Kalluri, R.6
-
57
-
-
0029921188
-
CD44/chondroitin sulfate proteoglycan and alpha 2 beta 1 integrin mediate human melanoma cell migration on type IV collagen and invasion of basement membranes
-
PMID:8868467
-
Knutson JR, Iida J, Fields GB, McCarthy JB. CD44/chondroitin sulfate proteoglycan and alpha 2 beta 1 integrin mediate human melanoma cell migration on type IV collagen and invasion of basement membranes. Mol Biol Cell 1996; 7:383-96; PMID:8868467
-
(1996)
Mol Biol Cell
, vol.7
, pp. 383-396
-
-
Knutson, J.R.1
Iida, J.2
Fields, G.B.3
McCarthy, J.B.4
-
58
-
-
0029852955
-
Integrin alpha 2 beta 1 in tumorigenic human osteosarcoma cell lines regulates cell adhesion, migration, and invasion by nteraction with type I collagen
-
PMID:9052985
-
Vihinen P, Riikonen T, Laine A, Heino J. Integrin alpha 2 beta 1 in tumorigenic human osteosarcoma cell lines regulates cell adhesion, migration, and invasion by nteraction with type I collagen. Cell Growth Differ 1996; 7:439-47; PMID:9052985
-
(1996)
Cell Growth Differ
, vol.7
, pp. 439-447
-
-
Vihinen, P.1
Riikonen, T.2
Laine, A.3
Heino, J.4
-
59
-
-
0029981104
-
Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha3 and anti-beta1 integrin antibodies
-
PMID:8824548
-
Tysnes BB, Larsen LF, Ness GO, Mahesparan R, Edvardsen K, Garcia-Cabrera I, et al. Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha3 and anti-beta1 integrin antibodies. Int J Cancer 1996; 67:777-84; PMID:8824548; http://dx.doi.org/10.1002/(SICI)1097-0215(19960917)67:6<777:: AID-IJC5>3.0.CO;2-O
-
(1996)
Int J Cancer
, vol.67
, pp. 777-784
-
-
Tysnes, B.B.1
Larsen, L.F.2
Ness, G.O.3
Mahesparan, R.4
Edvardsen, K.5
Garcia-Cabrera, I.6
-
60
-
-
0030007495
-
Tenascin mediates human glioma cell migration and modulates cell migration on fibronectin
-
PMID:8907709
-
Deryugina EI, Bourdon MA. Tenascin mediates human glioma cell migration and modulates cell migration on fibronectin. J Cell Sci 1996; 109:643-52; PMID:8907709
-
(1996)
J Cell Sci
, vol.109
, pp. 643-652
-
-
Deryugina, E.I.1
Bourdon, M.A.2
-
61
-
-
0345490851
-
Metastatic dissemination of human ovarian epithelial carcinoma is promoted by alpha2beta1-integrin-mediated interaction with type I collagen
-
PMID:10207247
-
Fishman DA, Kearns A, Chilukuri K, Bafetti LM, O'Toole EA, Georgacopoulos J, et al. Metastatic dissemination of human ovarian epithelial carcinoma is promoted by alpha2beta1-integrin-mediated interaction with type I collagen. Invasion Metastasis 1998; 18:15-26; PMID:10207247; http://dx.doi.org/10.1159/ 000024495
-
(1998)
Invasion Metastasis
, vol.18
, pp. 15-26
-
-
Fishman, D.A.1
Kearns, A.2
Chilukuri, K.3
Bafetti, L.M.4
O'Toole, E.A.5
Georgacopoulos, J.6
-
62
-
-
0032590002
-
Role of beta1 integrins in adhesion and invasion of hepatocellular carcinoma cells
-
PMID: 9862852
-
Masumoto A, Arao S, Otsuki M. Role of beta1 integrins in adhesion and invasion of hepatocellular carcinoma cells. Hepatology 1999; 29:68-74; PMID: 9862852; http://dx.doi.org/10.1002/hep.510290146
-
(1999)
Hepatology
, vol.29
, pp. 68-74
-
-
Masumoto, A.1
Arao, S.2
Otsuki, M.3
-
63
-
-
34848816931
-
Rab25 associates with alpha5-beta1 integrin to promote invasive migration in 3D microenvironments
-
PMID:17925226
-
Caswell PT, Spence HJ, Parsons M, White DP, Clark K, Cheng KW, et al. Rab25 associates with alpha5-beta1 integrin to promote invasive migration in 3D microenvironments. Dev Cell 2007; 13:496-510; PMID:17925226; http://dx.doi.org/10.1016/j.devcel.2007.08.012
-
(2007)
Dev Cell
, vol.13
, pp. 496-510
-
-
Caswell, P.T.1
Spence, H.J.2
Parsons, M.3
White, D.P.4
Clark, K.5
Cheng, K.W.6
-
64
-
-
0027673462
-
The role of beta 1 integrins in tumors
-
PMID:7504957
-
Juliano RL. The role of beta 1 integrins in tumors. Semin Cancer Biol 1993; 4:277-83; PMID:7504957
-
(1993)
Semin Cancer Biol
, vol.4
, pp. 277-283
-
-
Juliano, R.L.1
-
65
-
-
0034256088
-
The alpha 3 beta 1 integrin is associated with mammary carcinoma cell metastasis, invasion, and gelatinase B (MMP-9) activity
-
PMID: 10897037
-
Morini M, Mottolese M, Ferrari N, Ghiorzo F, Buglioni S, Mortarini R, et al. The alpha 3 beta 1 integrin is associated with mammary carcinoma cell metastasis, invasion, and gelatinase B (MMP-9) activity. Int J Cancer 2000; 87:336-42; PMID: 10897037; http://dx.doi.org/10.1002/1097-0215(20000801)87: 3<336::AID-IJC5>3.0.CO;2-3
-
(2000)
Int J Cancer
, vol.87
, pp. 336-342
-
-
Morini, M.1
Mottolese, M.2
Ferrari, N.3
Ghiorzo, F.4
Buglioni, S.5
Mortarini, R.6
-
66
-
-
0042922958
-
AlphaV- And beta1-integrin subunits are commonly expressed in malignant effusions from ovarian carcinoma patients
-
PMID:12893184
-
Davidson B, Goldberg I, Reich R, Tell L, Dong HP, Trope' CG, et al. AlphaV- and beta1-integrin subunits are commonly expressed in malignant effusions from ovarian carcinoma patients. Gynecol Oncol 2003; 90:248-57; PMID:12893184; http://dx.doi.org/10.1016/S0090-8258(03)00321-4
-
(2003)
Gynecol Oncol
, vol.90
, pp. 248-257
-
-
Davidson, B.1
Goldberg, I.2
Reich, R.3
Tell, L.4
Dong, H.P.5
Trope, C.G.6
-
67
-
-
80054970825
-
An in vitro correlation of metastatic capacity, substrate rigidity, and ECM composition
-
PMID: 21732405
-
Indra I, Beningo KA. An in vitro correlation of metastatic capacity, substrate rigidity, and ECM composition. J Cell Biochem 2011; 112:3151-8; PMID: 21732405; http://dx.doi.org/10.1002/jcb.23241
-
(2011)
J Cell Biochem
, vol.112
, pp. 3151-3158
-
-
Indra, I.1
Beningo, K.A.2
-
68
-
-
0030051164
-
Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells
-
PMID:8546226
-
Matsuura N, Puzon-McLaughlin W, Irie A, Morikawa Y, Kakudo K, Takada Y. Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells. Am J Pathol 1996; 148:55-61; PMID:8546226
-
(1996)
Am J Pathol
, vol.148
, pp. 55-61
-
-
Matsuura, N.1
Puzon-McLaughlin, W.2
Irie, A.3
Morikawa, Y.4
Kakudo, K.5
Takada, Y.6
-
69
-
-
0029847196
-
Role of alpha 2 beta 1- And alpha 3 beta 1-integrin in the peritoneal implantation of scirrhous gastric carcinoma
-
PMID:8912536
-
Nishimura S, Chung YS, Yashiro M, Inoue T, Sowa M. Role of alpha 2 beta 1- and alpha 3 beta 1-integrin in the peritoneal implantation of scirrhous gastric carcinoma. Br J Cancer 1996; 74:1406-12; PMID:8912536; http://dx.doi.org/10.1038/bjc.1996.556
-
(1996)
Br J Cancer
, vol.74
, pp. 1406-1412
-
-
Nishimura, S.1
Chung, Y.S.2
Yashiro, M.3
Inoue, T.4
Sowa, M.5
-
70
-
-
0037468119
-
Expression level of integrin alpha 5 on tumour cells affects the rate of metastasis to the kidney
-
PMID:12610521
-
Tani N, Higashiyama S, Kawaguchi N, Madarame J, Ota I, Ito Y, et al. Expression level of integrin alpha 5 on tumour cells affects the rate of metastasis to the kidney. Br J Cancer 2003; 88:327-33; PMID:12610521; http://dx.doi.org/10.1038/sj.bjc.6600710
-
(2003)
Br J Cancer
, vol.88
, pp. 327-333
-
-
Tani, N.1
Higashiyama, S.2
Kawaguchi, N.3
Madarame, J.4
Ota, I.5
Ito, Y.6
-
71
-
-
0035885933
-
Reduction in druginduced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells
-
PMID:11535527
-
Hazlehurst LA, Valkov N, Wisner L, Storey JA, Boulware D, Sullivan DM, et al. Reduction in druginduced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells. Blood 2001; 98:1897-903; PMID:11535527; http://dx.doi.org/10.1182/blood.V98.6.1897
-
(2001)
Blood
, vol.98
, pp. 1897-1903
-
-
Hazlehurst, L.A.1
Valkov, N.2
Wisner, L.3
Storey, J.A.4
Boulware, D.5
Sullivan, D.M.6
-
72
-
-
0034606657
-
Epigenetic determinants of resistance to etoposide regulation of Bcl-X(L) and Bax by tumor microenvironmental factors
-
PMID:10620629
-
Taylor ST, Hickman JA, Dive C. Epigenetic determinants of resistance to etoposide regulation of Bcl-X(L) and Bax by tumor microenvironmental factors. J Natl Cancer Inst 2000; 92:18-23; PMID:10620629; http://dx.doi.org/10.1093/jnci/ 92.1.18
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 18-23
-
-
Taylor, S.T.1
Hickman, J.A.2
Dive, C.3
-
73
-
-
0033032317
-
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
-
PMID:10371505
-
Sethi T, Rintoul RC, Moore SM, MacKinnon AC, Salter D, Choo C, et al. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med 1999; 5:662-8; PMID:10371505; http://dx.doi.org/10.1038/9511
-
(1999)
Nat Med
, vol.5
, pp. 662-668
-
-
Sethi, T.1
Rintoul, R.C.2
Moore, S.M.3
MacKinnon, A.C.4
Salter, D.5
Choo, C.6
-
74
-
-
0036204974
-
Extracellular matrix regulation of drug resistance in small-cell lung cancer
-
Lond PMID:11914104
-
Rintoul RC, Sethi T. Extracellular matrix regulation of drug resistance in small-cell lung cancer. Clin Sci (Lond) 2002; 102:417-24; PMID:11914104; http://dx.doi.org/10.1042/CS20010216
-
(2002)
Clin Sci
, vol.102
, pp. 417-424
-
-
Rintoul, R.C.1
Sethi, T.2
-
75
-
-
0035899331
-
Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells
-
PMID:11526484
-
Aoudjit F, Vuori K. Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene 2001; 20:4995-5004; PMID:11526484; http://dx.doi.org/10.1038/sj.onc.1204554
-
(2001)
Oncogene
, vol.20
, pp. 4995-5004
-
-
Aoudjit, F.1
Vuori, K.2
-
76
-
-
0036253054
-
Ionizing radiation induces up-regulation of functional beta1-integrin in human lung tumour cell lines in vitro
-
PMID:12020426
-
Cordes N, Blaese MA, Meineke V, Van Beuningen D. Ionizing radiation induces up-regulation of functional beta1-integrin in human lung tumour cell lines in vitro. Int J Radiat Biol 2002; 78:347-57; PMID:12020426; http://dx.doi.org/10.1080/09553000110117340
-
(2002)
Int J Radiat Biol
, vol.78
, pp. 347-357
-
-
Cordes, N.1
Blaese, M.A.2
Meineke, V.3
Van Beuningen, D.4
-
77
-
-
0038751716
-
Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro
-
PMID:12778079
-
Cordes N, van Beuningen D. Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro. Br J Cancer 2003; 88: 1470-9; PMID:12778079; http://dx.doi.org/10.1038/ sj.bjc.6600912
-
(2003)
Br J Cancer
, vol.88
, pp. 1470-1479
-
-
Cordes, N.1
Van Beuningen, D.2
-
78
-
-
33644778551
-
beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury
-
PMID:16247454
-
Cordes N, Seidler J, Durzok R, Geinitz H, Brakebusch C. beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury. Oncogene 2006; 25:1378-90; PMID:16247454; http://dx.doi.org/10.1038/sj.onc.1209164
-
(2006)
Oncogene
, vol.25
, pp. 1378-1390
-
-
Cordes, N.1
Seidler, J.2
Durzok, R.3
Geinitz, H.4
Brakebusch, C.5
-
79
-
-
33748685968
-
ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through beta1 integrin-dependent activation of PI3-kinase
-
PMID:16410797
-
Hodkinson PS, Elliott T, Wong WS, Rintoul RC, Mackinnon AC, Haslett C, et al. ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through beta1 integrin-dependent activation of PI3-kinase. Cell Death Differ 2006; 13:1776-88; PMID:16410797; http://dx.doi.org/10.1038/sj.cdd.4401849
-
(2006)
Cell Death Differ
, vol.13
, pp. 1776-1788
-
-
Hodkinson, P.S.1
Elliott, T.2
Wong, W.S.3
Rintoul, R.C.4
Mackinnon, A.C.5
Haslett, C.6
-
80
-
-
49249107671
-
Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
-
PMID:18519702
-
Park CC, Zhang HJ, Yao ES, Park CJ, Bissell MJ. Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. Cancer Res 2008; 68:4398-405; PMID:18519702; http://dx.doi.org/10.1158/0008- 5472.CAN-07-6390
-
(2008)
Cancer Res
, vol.68
, pp. 4398-4405
-
-
Park, C.C.1
Zhang, H.J.2
Yao, E.S.3
Park, C.J.4
Bissell, M.J.5
-
81
-
-
79960363201
-
Radiobiology goes 3D: How ECM and cell morphology impact on cell survival after irradiation
-
PMID: 21704412
-
Eke I, Cordes N. Radiobiology goes 3D: how ECM and cell morphology impact on cell survival after irradiation. Radiother Oncol 2011; 99:271-8; PMID: 21704412; http://dx.doi.org/10.1016/j.radonc.2011.06.007
-
(2011)
Radiother Oncol
, vol.99
, pp. 271-278
-
-
Eke, I.1
Cordes, N.2
-
82
-
-
13944256944
-
Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth, and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xenografts
-
PMID:15735038
-
Yau CY, Wheeler JJ, Sutton KL, Hedley DW. Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth, and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xenografts. Cancer Res 2005; 65:1497-504;PMID:15735038; http://dx.doi.org/10. 1158/0008-5472.CAN-04-2940
-
(2005)
Cancer Res
, vol.65
, pp. 1497-1504
-
-
Yau, C.Y.1
Wheeler, J.J.2
Sutton, K.L.3
Hedley, D.W.4
-
83
-
-
34250774522
-
The role of integrin-linked kinase in melanoma cell migration, invasion, and tumor growth
-
PMID:17575101
-
Wong RP, Ng P, Dedhar S, Li G. The role of integrin-linked kinase in melanoma cell migration, invasion, and tumor growth. Mol Cancer Ther 2007; 6:1692-700; PMID:17575101; http://dx.doi.org/10.1158/1535-7163.MCT-07-0134
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1692-1700
-
-
Wong, R.P.1
Ng, P.2
Dedhar, S.3
Li, G.4
-
84
-
-
38349111410
-
Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK)
-
PMID: 18202010
-
Edwards LA, Woo J, Huxham LA, Verreault M, Dragowska WH, Chiu G, et al. Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK). Mol Cancer Ther 2008; 7:59-70; PMID: 18202010; http://dx.doi.org/10.1158/1535-7163.MCT-07-0329
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 59-70
-
-
Edwards, L.A.1
Woo, J.2
Huxham, L.A.3
Verreault, M.4
Dragowska, W.H.5
Chiu, G.6
-
85
-
-
31544439674
-
Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival
-
PMID:16397254
-
Troussard AA, McDonald PC, Wederell ED, Mawji NM, Filipenko NR, Gelmon KA, et al. Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival. Cancer Res 2006; 66:393-403; PMID:16397254; http://dx.doi.org/10.1158/0008-5472. CAN-05-2304
-
(2006)
Cancer Res
, vol.66
, pp. 393-403
-
-
Troussard, A.A.1
McDonald, P.C.2
Wederell, E.D.3
Mawji, N.M.4
Filipenko, N.R.5
Gelmon, K.A.6
-
86
-
-
79960150764
-
Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models
-
PMID:20234193
-
Walsh C, Tanjoni I, Uryu S, Tomar A, Nam JO, Luo H, et al. Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models. Cancer Biol Ther 2010; 9:778-90; PMID:20234193; http://dx.doi.org/10.4161/cbt.9.10.11433
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 778-790
-
-
Walsh, C.1
Tanjoni, I.2
Uryu, S.3
Tomar, A.4
Nam, J.O.5
Luo, H.6
-
87
-
-
57349153946
-
A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth
-
PMID:18989950
-
Golubovskaya VM, Nyberg C, Zheng M, Kweh F, Magis A, Ostrov D, et al. A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. J Med Chem 2008; 51:7405-16; PMID:18989950; http://dx.doi.org/10.1021/jm800483v
-
(2008)
J Med Chem
, vol.51
, pp. 7405-7416
-
-
Golubovskaya, V.M.1
Nyberg, C.2
Zheng, M.3
Kweh, F.4
Magis, A.5
Ostrov, D.6
-
88
-
-
40949152523
-
Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271
-
PMID:18339875
-
Roberts WG, Ung E, Whalen P, Cooper B, Hulford C, Autry C, et al. Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271. Cancer Res 2008; 68:1935-44; PMID:18339875; http://dx.doi.org/10.1158/0008-5472.CAN-07-5155
-
(2008)
Cancer Res
, vol.68
, pp. 1935-1944
-
-
Roberts, W.G.1
Ung, E.2
Whalen, P.3
Cooper, B.4
Hulford, C.5
Autry, C.6
-
89
-
-
34250163937
-
A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth
-
PMID: 17219439
-
Shi Q, Hjelmeland AB, Keir ST, Song L, Wickman S, Jackson D, et al. A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. Mol Carcinog 2007; 46:488-96; PMID: 17219439; http://dx.doi.org/10.1002/mc.20297
-
(2007)
Mol Carcinog
, vol.46
, pp. 488-496
-
-
Shi, Q.1
Hjelmeland, A.B.2
Keir, S.T.3
Song, L.4
Wickman, S.5
Jackson, D.6
-
90
-
-
36348933509
-
Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma
-
PMID: 18006843
-
Halder J, Lin YG, Merritt WM, Spannuth WA, Nick AM, Honda T, et al. Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma. Cancer Res 2007; 67:10976-83; PMID: 18006843; http://dx.doi.org/10.1158/0008-5472.CAN-07-2667
-
(2007)
Cancer Res
, vol.67
, pp. 10976-10983
-
-
Halder, J.1
Lin, Y.G.2
Merritt, W.M.3
Spannuth, W.A.4
Nick, A.M.5
Honda, T.6
-
91
-
-
68449092818
-
A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer
-
PMID:19571674
-
Hochwald SN, Nyberg C, Zheng M, Zheng D, Wood C, Massoll NA, et al. A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer. Cell Cycle 2009; 8:2435-43; PMID:19571674; http://dx.doi.org/10.4161/cc. 8.15.9145
-
(2009)
Cell Cycle
, vol.8
, pp. 2435-2443
-
-
Hochwald, S.N.1
Nyberg, C.2
Zheng, M.3
Zheng, D.4
Wood, C.5
Massoll, N.A.6
-
92
-
-
56249095776
-
An alpha5beta1 integrin inhibitor attenuates glioma growth
-
PMID:18804537
-
Färber K, Synowitz M, Zahn G, Vossmeyer D, Stragies R, van Rooijen N, et al. An alpha5beta1 integrin inhibitor attenuates glioma growth. Mol Cell Neurosci 2008; 39:579-85; PMID:18804537; http://dx.doi.org/10.1016/j.mcn.2008. 08.005
-
(2008)
Mol Cell Neurosci
, vol.39
, pp. 579-585
-
-
Färber, K.1
Synowitz, M.2
Zahn, G.3
Vossmeyer, D.4
Stragies, R.5
Van Rooijen, N.6
-
93
-
-
0037457423
-
Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice
-
PMID:12584749
-
Stoeltzing O, Liu W, Reinmuth N, Fan F, Parry GC, Parikh AA, et al. Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. Int J Cancer 2003; 104:496-503; PMID:12584749; http://dx.doi.org/10.1002/ijc.10958
-
(2003)
Int J Cancer
, vol.104
, pp. 496-503
-
-
Stoeltzing, O.1
Liu, W.2
Reinmuth, N.3
Fan, F.4
Parry, G.C.5
Parikh, A.A.6
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