Metastatic dissemination of human ovarian epithelial carcinoma is promoted by α2β1-integrin-mediated interaction with type I collagen

Invasion and Metastasis

Volumn 18, Issue 1, 1998, Pages 15-26

  Fishman, David A ^a   Kearns, Alicia ^a   Chilukuri, Krishna ^a   Bafetti, Lisa M ^a   O'Toole, Edel A ^a   Georgacopoulos, Joanne ^a   Ravosa, Matthew J ^a   Stack, M Sharon ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cell motility; Gelatinase; Matrix metalloproteinase; Ovarian carcinoma; Type I collagen; 2 1 integrin

Indexed keywords

BIOTIN; BLOCKING ANTIBODY; COLLAGEN TYPE 1; COLLOIDAL GOLD; ENZYME PRECURSOR; GELATINASE A; GLASS; INTEGRIN; METALLOPROTEINASE; PEPTIDE; PROTEIN ANTIBODY; PROTEIN SUBUNIT; PROTEINASE; SCLEROPROTEIN;

ARTICLE; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CONCENTRATION RESPONSE; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MESOTHELIUM; OVARY CARCINOMA; PERITONEUM METASTASIS; PHENOTYPE; TUMOR CELL CULTURE;

EID: 0345490851     PISSN: 02511789     EISSN: None     Source Type: Journal    
DOI: 10.1159/000024495     Document Type: Article

References (41)

1. Auersperg N, Maines-Bandiera SL, Kruk PA: Human ovarian surface epithelium: Growth patterns and differentiation; in Sharp F, Mason P, Blacket T, Berek J (eds): Ovarian Cancer III. London, Chapman & Hall, 1994, pp 157-169.
2. Young RC, Fuks Z, Hoskins WJ: Cancer of the ovary; in De Vita VT, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology. Philadelphia, Lippincott, 1989, pp 1162-1195.
3. Czernobilsky B, Moll R, Levy M, Franke WW: Coexpression of cytokeratin and vimentin filaments in mesothelial, granulosa, and rete ovarii cells of the human ovary. Eur J Cell Biol, 1985;37:175-190.
4. Auersperg N, Maclaren IA, Kruk PA: Ovarian surface epithelium: Autonomous production of connective tissue-type extracellular matrix. Biol Reprod 1991;44:717-724.
5. Niedbala MJ, Crickard K, Bernacki RJ: Interactions of human ovarian tumor cells with human mesothelial cells grown on extracellular matrix. Exp Cell Res 1985;160:499-513.
6. Sawada M, Shii J, Akedo H, Tanizawa O: An experimental model for ovarian tumor invasion of cultured mesothelial cell monolayer. Lab Invest 1994;70:333-338.
7. Cannistra SA, Ottensmeier C, Nihoff J, Orta B, DiCarlo J: Expression and function of β1 and αvβ3 integrins in ovarian cancer. Gynecol Oncol 1995;58:216-225.
8. Hynes RO: Integrins: Versatility, modulation and signaling in cell adhesion. Cell 1992;69:11-25.
9. Huttenlocher A, Sandborg RR, Horwitz AF: Adhesion in cell migration. Curr Opin Cell Biol 1995;7:697-706.
10. Werb Z, Tremble PM, Behrendtsen O, Crowley E, Damsky CH: Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol 1989;109:877-889.
11. Seftor REB, Seftor EA, Stetler-Stevenson WG, Hendrix MJC: The 72 kDa type IV collagenase is modulated via differential expression of alphavbeta3 and alpha5betal integrins during melanoma cell invasion. Cancer Res 1993;53:3411-3415.
12. Seftor REB, Seftor EA, Gehlsen KR, Stetler-Stevenson WG, Brown PD, Ruoslahti E, Hendrix MJC: Role of the αvβ3 integrin in human melanoma cell invasion. Proc Natl Acad Sci USA 1992;89:1557-1561.
13. Schwartz MA, Schaller MD, Ginsberg MH: Integrins: Emerging paradigms of signal transduction. Annu Rev Cell Dev Biol 1995;11:549-599.
14. Liotta LA, Rao CN, Wewer UM: Biochemical interactions of tumor cells with the basement membrane. Annu Rev Biochem 1986;55:1037-1057.
15. Staatz WD, Fok KM, Zutter MM, Adams SP, Rodriguez BA, Santoro SA: Identification of a tetrapeptide recognition sequence for the α2β1 integrin in collagen. J Biol Chem 1991;266:7363-7367.
16. Santoro SA, Zutter MM, Wu JE, Staatz WD, Saelman EUM, Keely PJ: Analysis of collagen receptors. Methods Enzymol 1994;245:147-183.
17. Dahlback B, Podack ER: Characterization of human S protein, an inhibitor of the membrane attack complex of complement: Demonstration of a free reactive thiol group. Biochemistry 1985;24:2368-2374.
18. Vuento M, Vaheri A: Purification of fibronectin from human plasma by affinity chromatography under non-denaturing conditions. Biochem J 1979:183:331-337.
19. Fishman DA, Bafetti LM, Stack MS: Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells. Invasion Metastasis 1997;16:150-159.
20. Rodriguez GC, Berchuck A, Whitaker RS, Schlossman D, Clarke-Pearson DL, Bast RC Jr: Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. Am J Obstet Gynecol 1991;745:750-761.
21. Moser TL, Pizzo SV, Bafetti LM, Fishman DA, Stack MS: Evidence for preferential adhesion of ovarian epithelial carcinoma cells to type I collagen mediated by the α2β1 integrin. Int J Cancer 1996;67:695-701.
22. Lämmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
23. Matsudaira P: Sequence from picomole quantities of proteins electro-blotted onto polyvinylidene difluoride membranes. J Biol Chem 1987; 262:10035-10038.
24. Albrecht-Buehler G: The phagokinetic tracks of 3T3 cells. Cell 1977; 11:395-404.
25. Kim JP, Zhang K, Chen JD, Kramer RH, Woodley DT: Vitronectin-driven human keratinocyte locomotion is mediated by the αvβ5 integrin receptor. J Biol Chem 1994;269: 26926-26932.
26. Stack MS, Gray RD, Pizzo SV: Modulation of murine B16F10 melanoma plasminogen activator production by a synthetic peptide derived from the laminin A chain. Cancer Res 1993;53:1998-2004.
27. Azzam HS, Thompson EW: Collagen-induced activation of the Mr 72,000 type IV collagenase in normal and malignant human fibroblastoid cells. Cancer Res 1992;52: 4540-4554.
28. Hemmler ME: VLA proteins in the integrin family: Structures, functions and their role in leukocytes. Annu Rev Immunol 1990;8:365-400.
29. Yamada KM: Adhesive recognition sequences. J Biol Chem 1991;266: 12809-12912.
30. Leavesley DI, Schwartz MA, Rosenfeld M, Cheresh DA: Integrin β1-and β3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. J Cell Biol 1993;121:163-170.
31. Fishman DA, Chilukuri K, Stack MS: Biochemical characterization of primary peritoneal carcinoma cell adhesion, migration, and proteinase activity. Gynecol Oncol 1997;67: 193-199.
32. Riikonen T, Westermarck J, Koivisto L, Broberg A, Kahari VM, Heino J: Integrin α2β1 is a positive regulator of collagenase (MMP-1) and collagenα1(I) gene expression. J Biol Chem 1995;270:13548-13552.
33. Fishman DA, Bafetti LM, Banionis S, Kearns AS, Chilukuri K, Stack MS: Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells. Cancer 1997; 80:1457-1463.
34. Harvey W, Amlot PL: Collagen production by human mesothelial cells in vitro. J Pathol 1983;139:337-347.
35. Stylianou E, Jenner LA, Davies M, Coles GA, Williams JD: Isolation, culture, and characterization of human peritoneal mesothelial cells. Kidney Int 1990:37:1563-1570.
36. Zhu GG, Risteli J, Puistola U, Kauppila A, Risteli L: Progressive ovarian carcinoma induces synthesis of type I and type III procollagens in the tumor tissue and peritoneal cavity. Cancer Res 1993;53:5028-5032.
37. Kauppila S, Saarela J, Stenback F, Risteli J, Kauppila A, Risteli L: Expression of mRNAs for type I and type III procollagens in serous ovarian cystadenomas and cystadenocarcinomas. Am J Pathol 1996;148: 539-548.
38. Yamada KM, Kennedy DW, Yamada SS, Gralnick H, Chen WT, Akiyama SK: Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration. Cancer Res 1990;50:4485-4496.
39. Gehlsen KR, Argraves WS, Pierschbacher MD, Ruoslahti E: Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides. J Cell Biol 1988;106:925-930.
40. Thompson EW, Yu M, Bueno J, Jin L, Maiti SN, Palao-Marco FL, Pulyawva H, Tamborlane JW, Tirgari R, Wapnir I, Azzam H: Collagen induced MMP-2 activation in breast cancer. Breast Cancer Res Treat 1994;31:357-370.
41. Gilles C, Polette M, Seiki M, Birembaut P, Thompson EW: Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma. Lab Invest 1997;76:651-660.