Expression levels of multidrug resistance-associated protein 4 (MRP4) in human leukemia and lymphoma cell lines, and the inhibitory effects of the MRP-specific inhibitor MK-571 on methotrexate distribution in rats

Experimental and Therapeutic Medicine

Volumn 4, Issue 3, 2012, Pages 524-532

  Takeuchi, Kenji ^a   Shibata, Masakazu ^a   Kashiyama, Eiji ^a   Umehara, Ken ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Leukemia; Lymphoma; Methotrexate; MK 571; Multidrug resistance associated protein 4

Indexed keywords

MESSENGER RNA; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 4; VERLUKAST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG INHIBITION; ERYTHROCYTE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOMA CELL LINE; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPLEEN; THYMUS;

EID: 84863944490     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2012.627     Document Type: Article

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