Upregulation of thrombospondin-1 expression by leptin in vascular smooth muscle cells via JAK2- and MAPK-dependent pathways

American Journal of Physiology - Cell Physiology

Volumn 303, Issue 2, 2012, Pages

  Chavez, Ronaldo J ^a   Haney, Rebecca M ^a   Cuadra, Rene H ^a   Ganguly, Rituparna ^a   Adapala, Ravi K ^a   Thodeti, Charles K ^a   Raman, Priya ^a  

^a Northeastern Ohio Medical University   (United States)

Author keywords

Janus kinase 2; Leptin; Mitogen activated protein kinase; Thrombospondin 1; Vascular smooth muscle cell

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLOHEXIMIDE; DACTINOMYCIN; JANUS KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; RECOMBINANT LEPTIN; SMALL INTERFERING RNA; THROMBOSPONDIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NORTHERN BLOTTING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; GENE EXPRESSION REGULATION; HUMANS; JANUS KINASE 2; LEPTIN; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; THROMBOSPONDIN 1; UP-REGULATION;

RODENTIA;

EID: 84863929664     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00008.2012     Document Type: Article

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