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Angewandte Chemie - International Edition

Volumn 50, Issue 33, 2011, Pages 7631-7635

Total synthesis of dinophysistoxin-2 and 2-epi-dinophysistoxin-2 and their PPase inhibition

(5) Pang, Yucheng a Fang, Chao a Twiner, Michael J b Miles, Christopher O c Forsyth, Craig J a

a OHIO STATE UNIVERSITY (United States)

b UNIVERSITY OF MICHIGAN DEARBORN (United States)

c NORWEGIAN VETERINARY INSTITUTE (Norway)

Author keywords

natural products; phosphatase inhibitors; structure activity relationships; total synthesis

Indexed keywords

ASYMMETRIC DIHYDROXYLATION; DIASTEREO-SELECTIVITY; INHIBITION ASSAYS; NATURAL PRODUCTS; ORDERS OF MAGNITUDE; PHOSPHATASE INHIBITORS; POTENT INHIBITION; STRUCTURE ACTIVITY RELATIONSHIPS; TITLE COMPOUNDS; TOTAL SYNTHESIS;

OLEFINS;

2 EPI DINOPHYSISTOXIN 2; 2-EPI-DINOPHYSISTOXIN-2; DINOPHYSISTOXIN 2; ENZYME INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE; PYRAN DERIVATIVE;

ARTICLE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ENZYME INHIBITORS; MOLECULAR CONFORMATION; PHOSPHOPROTEIN PHOSPHATASES; PYRANS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79961243580 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201101741 Document Type: Article

Times cited : (14)

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