Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression

Science Translational Medicine

Volumn 4, Issue 142, 2012, Pages

  Stallings Mann, Melody L ^a   Waldmann, Jens ^a,b   Zhang, Ying ^a   Miller, Erin ^a   Gauthier, Mona L ^c   Visscher, Daniel W ^d   Downey, Gregory P ^e,f,g   Radisky, Evette S ^a   Fields, Alan P ^a   Radisky, Derek C ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY HOSPITAL MARBURG   (Germany)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d MAYO CLINIC CANCER CENTER   (United States)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^f Children's Hospital Colorado   (United States)

^g UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERSTITIAL COLLAGENASE; K RAS PROTEIN; MATRIX METALLOPROTEINASE; MESSENGER RNA; RAC1 PROTEIN; RAC1B PROTEIN; STROMELYSIN; UNCLASSIFIED DRUG; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER STAGING; CONTROLLED STUDY; DISEASE ASSOCIATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; MALE; MATRIX METALLOPROTEINASE 3 GENE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; RAC1B GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ADENOMA; AGING; ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; DISEASE PROGRESSION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 3; MESODERM; MICE; MICE, TRANSGENIC; NEUROPEPTIDES; ONCOGENES; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; VIMENTIN;

EID: 84863908604     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3004062     Document Type: Article

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