메뉴 건너뛰기




Volumn 6, Issue 1, 2012, Pages 80-86

The role of the NLRP3 inflammasome in fibrosis

Author keywords

Caspase 1; Fibrosis; IL 1 ; IL 18; NLRP3 Inflammasome; Pattern Recognition Receptors; TGF 1

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA;

EID: 84863906876     PISSN: None     EISSN: 18743129     Source Type: Journal    
DOI: 10.2174/1874312901206010080     Document Type: Article
Times cited : (93)

References (64)
  • 1
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn TA. Cellular and molecular mechanisms of fibrosis. J Pathol 2008; 214: 199-210.
    • (2008) J Pathol , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 2
    • 80051556802 scopus 로고    scopus 로고
    • Viral infection in acute exacerbation of idiopathic pulmonary fibrosis
    • Wootton SC, Kim DS, Kondoh Y, et al. Viral infection in acute exacerbation of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2011; 183: 1698-702.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1698-1702
    • Wootton, S.C.1    Kim, D.S.2    Kondoh, Y.3
  • 3
    • 79953730806 scopus 로고    scopus 로고
    • Immunological status does not influence hepatitis c virus or liver fibrosis in HIV-hepatitis C viruscoinfected patients
    • Collazos J, Carton JA, Asensi V. Immunological status does not influence hepatitis c virus or liver fibrosis in HIV-hepatitis C viruscoinfected patients. AIDS Res Hum Retroviruses 2011; 27: 383-9.
    • (2011) AIDS Res Hum Retroviruses , vol.27 , pp. 383-389
    • Collazos, J.1    Carton, J.A.2    Asensi, V.3
  • 4
    • 77957884094 scopus 로고    scopus 로고
    • Pathogenetic mechanisms in radiation fibrosis
    • Yarnold J, Brotons MC. Pathogenetic mechanisms in radiation fibrosis. Radiother Oncol 2010; 97: 149-61.
    • (2010) Radiother Oncol , vol.97 , pp. 149-161
    • Yarnold, J.1    Brotons, M.C.2
  • 6
    • 22444433175 scopus 로고    scopus 로고
    • NLRs join TLRs as innate sensors of pathogens
    • Martinon F, Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol 2005; 26: 447-54.
    • (2005) Trends Immunol , vol.26 , pp. 447-454
    • Martinon, F.1    Tschopp, J.2
  • 8
    • 70349471022 scopus 로고    scopus 로고
    • Quantitative analysis and prediction of curvature in leucine-rich repeat proteins
    • Hindle KL, Bella J, Lovell SC. Quantitative analysis and prediction of curvature in leucine-rich repeat proteins. Proteins 2009; 77: 342-58.
    • (2009) Proteins , vol.77 , pp. 342-358
    • Hindle, K.L.1    Bella, J.2    Lovell, S.C.3
  • 9
    • 23344431978 scopus 로고    scopus 로고
    • The molecular structure of the Toll-like receptor 3 ligand-binding domain
    • Bell JK, Botos I, Hall PR, et al. The molecular structure of the Toll-like receptor 3 ligand-binding domain. Proc Natl Acad Sci USA 2005; 102: 10976-80.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10976-10980
    • Bell, J.K.1    Botos, I.2    Hall, P.R.3
  • 10
    • 0035474227 scopus 로고    scopus 로고
    • The NOD: A signaling module that regulates apoptosis and host defense against pathogens
    • Inohara N, Nunez G. The NOD: a signaling module that regulates apoptosis and host defense against pathogens. Oncogene 2001; 20: 6473-81.
    • (2001) Oncogene , vol.20 , pp. 6473-6481
    • Inohara, N.1    Nunez, G.2
  • 11
    • 35348932070 scopus 로고    scopus 로고
    • Intracellular NOD-like receptors in host defense and disease
    • Kanneganti TD, Lamkanfi M, Nunez G. Intracellular NOD-like receptors in host defense and disease. Immunity 2007; 27: 549-59.
    • (2007) Immunity , vol.27 , pp. 549-559
    • Kanneganti, T.D.1    Lamkanfi, M.2    Nunez, G.3
  • 13
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011; 469: 221-5.
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 14
    • 79957597757 scopus 로고    scopus 로고
    • Mitochondria in innate immune responses
    • West AP, Shadel GS, Ghosh S. Mitochondria in innate immune responses. Nat Rev Immunol 2011; 11: 389-402.
    • (2011) Nat Rev Immunol , vol.11 , pp. 389-402
    • West, A.P.1    Shadel, G.S.2    Ghosh, S.3
  • 16
    • 79956187649 scopus 로고    scopus 로고
    • Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity
    • Lalor SJ, Dungan LS, Sutton CE, Basdeo SA, Fletcher JM, Mills KH. Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity. J Immunol 2011; 186: 5738-48.
    • (2011) J Immunol , vol.186 , pp. 5738-5748
    • Lalor, S.J.1    Dungan, L.S.2    Sutton, C.E.3    Basdeo, S.A.4    Fletcher, J.M.5    Mills, K.H.6
  • 18
    • 79952313959 scopus 로고    scopus 로고
    • Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes
    • Dai X, Sayama K, Tohyama M, et al. Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes. J Allergy Clin Immunol 2011; 127: 806-14.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 806-814
    • Dai, X.1    Sayama, K.2    Tohyama, M.3
  • 20
    • 79960557902 scopus 로고    scopus 로고
    • Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome
    • Mortaz E, Henricks PA, Kraneveld AD, Givi ME, Garssen J, Folkerts G. Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome. Biochim Biophys Acta 2011; 181: 1104-10.
    • (2011) Biochim Biophys Acta , vol.181 , pp. 1104-1110
    • Mortaz, E.1    Henricks, P.A.2    Kraneveld, A.D.3    Givi, M.E.4    Garssen, J.5    Folkerts, G.6
  • 22
    • 0028107827 scopus 로고
    • Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: A (p20/p10)2 homodimer
    • Walker NP, Talanian RV, Brady KD, et al. Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer. Cell 1994; 78: 343-52.
    • (1994) Cell , vol.78 , pp. 343-352
    • Walker, N.P.1    Talanian, R.V.2    Brady, K.D.3
  • 23
    • 15844393942 scopus 로고    scopus 로고
    • Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme
    • Yamin TT, Ayala JM, Miller DK. Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme. J Biol Chem 1996; 271: 13273-82.
    • (1996) J Biol Chem , vol.271 , pp. 13273-13282
    • Yamin, T.T.1    Ayala, J.M.2    Miller, D.K.3
  • 24
    • 0028170376 scopus 로고
    • Structure and mechanism of interleukin-1 beta converting enzyme
    • Wilson KP, Black JA, Thomson JA, et al. Structure and mechanism of interleukin-1 beta converting enzyme. Nature 1994; 370: 270-5.
    • (1994) Nature , vol.370 , pp. 270-275
    • Wilson, K.P.1    Black, J.A.2    Thomson, J.A.3
  • 25
    • 33747191203 scopus 로고    scopus 로고
    • The inflammasome: First line of the immune response to cell stress
    • Ogura Y, Sutterwala FS, Flavell RA. The inflammasome: first line of the immune response to cell stress. Cell 2006; 126: 659-62.
    • (2006) Cell , vol.126 , pp. 659-662
    • Ogura, Y.1    Sutterwala, F.S.2    Flavell, R.A.3
  • 26
    • 33748135979 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: Role of microtubules
    • Carta S, Tassi S, Semino C, et al. Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules. Blood 2006; 108: 1618-26.
    • (2006) Blood , vol.108 , pp. 1618-1626
    • Carta, S.1    Tassi, S.2    Semino, C.3
  • 27
    • 37549002511 scopus 로고    scopus 로고
    • The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
    • Shao W, Yeretssian G, Doiron K, Hussain SN, Saleh M. The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J Biol Chem 2007; 282: 36321-9.
    • (2007) J Biol Chem , vol.282 , pp. 36321-36329
    • Shao, W.1    Yeretssian, G.2    Doiron, K.3    Hussain, S.N.4    Saleh, M.5
  • 28
    • 39749084641 scopus 로고    scopus 로고
    • Active caspase-1 is a regulator of unconventional protein secretion
    • Keller M, Ruegg A, Werner S, Beer H-D. Active caspase-1 is a regulator of unconventional protein secretion. Cell 2008; 132: 818-31.
    • (2008) Cell , vol.132 , pp. 818-831
    • Keller, M.1    Ruegg, A.2    Werner, S.3    Beer, H-D.4
  • 29
    • 0032747002 scopus 로고    scopus 로고
    • Interleukin-18
    • Dinarello CA. Interleukin-18. Methods 1999; 19: 121-32.
    • (1999) Methods , vol.19 , pp. 121-132
    • Dinarello, C.A.1
  • 30
    • 0031739525 scopus 로고    scopus 로고
    • Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme
    • Dinarello CA. Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. Ann NY Acad Sci 1998; 856: 1-11.
    • (1998) Ann NY Acad Sci , vol.856 , pp. 1-11
    • Dinarello, C.A.1
  • 31
    • 0023904804 scopus 로고
    • Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways
    • Fenton MJ, Vermeulen MW, Clark BD, Webb AC, Auron PE. Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways. J Immunol 1988; 140: 2267-73.
    • (1988) J Immunol , vol.140 , pp. 2267-2273
    • Fenton, M.J.1    Vermeulen, M.W.2    Clark, B.D.3    Webb, A.C.4    Auron, P.E.5
  • 32
    • 0035575705 scopus 로고    scopus 로고
    • Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells
    • Sugawara S, Uehara A, Nochi T, et al. Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells. J Immunol 2001; 167: 6568-75.
    • (2001) J Immunol , vol.167 , pp. 6568-6575
    • Sugawara, S.1    Uehara, A.2    Nochi, T.3
  • 33
    • 0034978471 scopus 로고    scopus 로고
    • Regulation of IL-18 expression in virus infection
    • Pirhonen J. Regulation of IL-18 expression in virus infection. Scand J Immunol 2001; 53: 533-9.
    • (2001) Scand J Immunol , vol.53 , pp. 533-539
    • Pirhonen, J.1
  • 34
    • 69249112562 scopus 로고    scopus 로고
    • Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling
    • Luo DD, Fielding C, Phillips A, Fraser D. Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling. Nephrol Dial Transplant 2009; 24: 2655-65.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2655-2665
    • Luo, D.D.1    Fielding, C.2    Phillips, A.3    Fraser, D.4
  • 35
    • 33846409095 scopus 로고    scopus 로고
    • Inflammatory cytokines induce the transformation of human dermal microvascular endothelial cells into myofibroblasts: A potential role in skin fibrogenesis
    • Chaudhuri V, Zhou L, Karasek M. Inflammatory cytokines induce the transformation of human dermal microvascular endothelial cells into myofibroblasts: a potential role in skin fibrogenesis. J Cutan Pathol 2007; 34: 146-53.
    • (2007) J Cutan Pathol , vol.34 , pp. 146-153
    • Chaudhuri, V.1    Zhou, L.2    Karasek, M.3
  • 36
    • 0023901511 scopus 로고
    • Modulation of fibroblast functions by interleukin 1: Increased steady-state accumulation of type I procollagen messenger RNAs and stimulation of other functions but not chemotaxis by human recombinant interleukin 1 alpha and beta
    • Postlethwaite AE, Raghow R, Stricklin GP, Poppleton H, Seyer JM, Kang AH. Modulation of fibroblast functions by interleukin 1: increased steady-state accumulation of type I procollagen messenger RNAs and stimulation of other functions but not chemotaxis by human recombinant interleukin 1 alpha and beta. J Cell Biol 1988; 106: 311-8.
    • (1988) J Cell Biol , vol.106 , pp. 311-318
    • Postlethwaite, A.E.1    Raghow, R.2    Stricklin, G.P.3    Poppleton, H.4    Seyer, J.M.5    Kang, A.H.6
  • 37
    • 0034967219 scopus 로고    scopus 로고
    • Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis
    • Kolb M, Margetts PJ, Anthony DC, Pitossi F, Gauldie J. Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. J Clin Invest 2001; 107: 1529-36.
    • (2001) J Clin Invest , vol.107 , pp. 1529-1536
    • Kolb, M.1    Margetts, P.J.2    Anthony, D.C.3    Pitossi, F.4    Gauldie, J.5
  • 38
    • 67049160679 scopus 로고    scopus 로고
    • Disruption of interleukin-1 signaling improves the quality of wound healing
    • Thomay AA, Daley JM, Sabo E, et al. Disruption of interleukin-1 signaling improves the quality of wound healing. Am J Pathol 2009; 174: 2129-36.
    • (2009) Am J Pathol , vol.174 , pp. 2129-2136
    • Thomay, A.A.1    Daley, J.M.2    Sabo, E.3
  • 39
    • 60349085971 scopus 로고    scopus 로고
    • The effect of daily administration of IL-18 on cardiac structure and function
    • Platis A, Yu Q, Moore D, Khojeini E, Tsau P, Larson D. The effect of daily administration of IL-18 on cardiac structure and function. Perfusion 2008; 23: 237-42.
    • (2008) Perfusion , vol.23 , pp. 237-242
    • Platis, A.1    Yu, Q.2    Moore, D.3    Khojeini, E.4    Tsau, P.5    Larson, D.6
  • 40
    • 48149112149 scopus 로고    scopus 로고
    • Felodipine reduces cardiac expression of IL-18 and perivascular fibrosis in fructose-fed rats
    • Xing SS, Tan HW, Bi XP, Zhong M, Zhang Y, Zhang W. Felodipine reduces cardiac expression of IL-18 and perivascular fibrosis in fructose-fed rats. Mol Med 2008; 14: 395-402.
    • (2008) Mol Med , vol.14 , pp. 395-402
    • Xing, S.S.1    Tan, H.W.2    Bi, X.P.3    Zhong, M.4    Zhang, Y.5    Zhang, W.6
  • 41
    • 79951846190 scopus 로고    scopus 로고
    • Basic calcium phosphate crystals induce monocyte/macrophage IL-1beta secretion through the NLRP3 inflammasome in vitro
    • Pazar B, Ea HK, Narayan S, et al. Basic calcium phosphate crystals induce monocyte/macrophage IL-1beta secretion through the NLRP3 inflammasome in vitro. J Immunol 2011; 186: 2495-502.
    • (2011) J Immunol , vol.186 , pp. 2495-2502
    • Pazar, B.1    Ea, H.K.2    Narayan, S.3
  • 42
    • 79551662979 scopus 로고    scopus 로고
    • Octacalcium phosphate crystals induce inflammation in vivo through interleukin-1 but independent of the NLRP3 inflammasome in mice
    • Narayan S, Pazar B, Ea HK, et al. Octacalcium phosphate crystals induce inflammation in vivo through interleukin-1 but independent of the NLRP3 inflammasome in mice. Arthritis Rheum 2011; 63: 422-33.
    • (2011) Arthritis Rheum , vol.63 , pp. 422-433
    • Narayan, S.1    Pazar, B.2    Ea, H.K.3
  • 43
    • 78349306055 scopus 로고    scopus 로고
    • Effects of interleukin-18 on cardiac fibroblast function and gene expression
    • Fix C, Bingham K, Carver W. Effects of interleukin-18 on cardiac fibroblast function and gene expression. Cytokine 2011; 53: 19-28.
    • (2011) Cytokine , vol.53 , pp. 19-28
    • Fix, C.1    Bingham, K.2    Carver, W.3
  • 45
    • 0029030393 scopus 로고
    • Fibroblasts as efficient antigen-presenting cells in lymphoid organs
    • Kundig TM, Bachmann MF, DiPaolo C, et al. Fibroblasts as efficient antigen-presenting cells in lymphoid organs. Science 1995; 268: 1343-7.
    • (1995) Science , vol.268 , pp. 1343-1347
    • Kundig, T.M.1    Bachmann, M.F.2    DiPaolo, C.3
  • 46
    • 77952742518 scopus 로고    scopus 로고
    • Analysis of antigen-presenting functionality of cultured rat hepatic stellate cells and transdifferentiated myofibroblasts
    • Bomble M, Tacke F, Rink L, Kovalenko E, Weiskirchen R. Analysis of antigen-presenting functionality of cultured rat hepatic stellate cells and transdifferentiated myofibroblasts. Biochem Biophys Res Commun 2010; 396: 342-7.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 342-347
    • Bomble, M.1    Tacke, F.2    Rink, L.3    Kovalenko, E.4    Weiskirchen, R.5
  • 47
    • 33750344702 scopus 로고    scopus 로고
    • Subepithelial myofibroblasts are novel nonprofessional APCs in the human colonic mucosa
    • Saada JI, Pinchuk IV, Barrera CA, et al. Subepithelial myofibroblasts are novel nonprofessional APCs in the human colonic mucosa. J Immunol 2006; 177: 5968-79.
    • (2006) J Immunol , vol.177 , pp. 5968-5979
    • Saada, J.I.1    Pinchuk, I.V.2    Barrera, C.A.3
  • 48
    • 0031201054 scopus 로고    scopus 로고
    • Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation
    • Smith RS, Smith TJ, Blieden TM, Phipps RP. Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation. Am J Pathol 1997; 151: 317-22.
    • (1997) Am J Pathol , vol.151 , pp. 317-322
    • Smith, R.S.1    Smith, T.J.2    Blieden, T.M.3    Phipps, R.P.4
  • 49
    • 36849056773 scopus 로고    scopus 로고
    • IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice
    • Gasse P, Mary C, Guenon I, et al. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J Clin Invest 2007; 117: 3786-99.
    • (2007) J Clin Invest , vol.117 , pp. 3786-3799
    • Gasse, P.1    Mary, C.2    Guenon, I.3
  • 50
    • 65649140025 scopus 로고    scopus 로고
    • Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis
    • Gasse P, Riteau N, Charron S, et al. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med 2009; 179: 903-13.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 903-913
    • Gasse, P.1    Riteau, N.2    Charron, S.3
  • 51
    • 76249115506 scopus 로고    scopus 로고
    • IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema
    • Couillin I, Vasseur V, Charron S, et al. IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema. J Immunol 2009; 183: 8195-202.
    • (2009) J Immunol , vol.183 , pp. 8195-8202
    • Couillin, I.1    Vasseur, V.2    Charron, S.3
  • 52
    • 47849132947 scopus 로고    scopus 로고
    • The NALP3 inflammasome is essential for the development of silicosis
    • Cassel SL, Eisenbarth SC, Lyer SS, et al. The NALP3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci USA 2008; 105: 9035-40.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9035-9040
    • Cassel, S.L.1    Eisenbarth, S.C.2    Lyer, S.S.3
  • 53
    • 69949090403 scopus 로고    scopus 로고
    • The innate immune response to DNA
    • Vilaysane A, Muruve DA. The innate immune response to DNA. Semin Immunol 2009; 21: 208-14.
    • (2009) Semin Immunol , vol.21 , pp. 208-214
    • Vilaysane, A.1    Muruve, D.A.2
  • 54
    • 43349086139 scopus 로고    scopus 로고
    • Detection of immune danger signals by NALP3
    • Martinon F. Detection of immune danger signals by NALP3. J Leukoc Biol 2008; 83: 507-11.
    • (2008) J Leukoc Biol , vol.83 , pp. 507-511
    • Martinon, F.1
  • 55
    • 78649771825 scopus 로고    scopus 로고
    • Infectious disease as aetiological factor in the pathogenesis of systemic sclerosis
    • Radic M, Martinovic KD, Radic J. Infectious disease as aetiological factor in the pathogenesis of systemic sclerosis. Neth J Med 2010; 68: 348-53.
    • (2010) Neth J Med , vol.68 , pp. 348-353
    • Radic, M.1    Martinovic, K.D.2    Radic, J.3
  • 58
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 2008; 88: 125-72.
    • (2008) Physiol Rev , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 60
    • 79951679204 scopus 로고    scopus 로고
    • Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
    • Kawaguchi M, Takahashi M, Hata T, et al. Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation 2011; 123: 594-604.
    • (2011) Circulation , vol.123 , pp. 594-604
    • Kawaguchi, M.1    Takahashi, M.2    Hata, T.3
  • 61
    • 33646414215 scopus 로고    scopus 로고
    • Autocrine loop between TGFbeta1 and IL-1beta through Smad3-and ERK-dependent pathways in rat pancreatic stellate cells
    • Aoki H, Ohnishi H, Hama K, et al. Autocrine loop between TGFbeta1 and IL-1beta through Smad3-and ERK-dependent pathways in rat pancreatic stellate cells. Am J Physiol Cell Physiol 2006; 290: C1100-C8.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Aoki, H.1    Ohnishi, H.2    Hama, K.3
  • 62
    • 34347402254 scopus 로고    scopus 로고
    • A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblastmediated stiffening of collagen gels
    • Leung LY, Tian D, Brangwynne CP, Weitz DA, Tschumperlin DJ. A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblastmediated stiffening of collagen gels. FASEB J 2007; 21: 2064-73.
    • (2007) FASEB J , vol.21 , pp. 2064-2073
    • Leung, L.Y.1    Tian, D.2    Brangwynne, C.P.3    Weitz, D.A.4    Tschumperlin, D.J.5
  • 63
    • 49849095099 scopus 로고    scopus 로고
    • Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose
    • Belmadani S, Zerfaoui M, Boulares HA, Palen DI, Matrougui K. Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose. Am J Physiol Heart Circ Physiol 2008; 295: H69-H76.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Belmadani, S.1    Zerfaoui, M.2    Boulares, H.A.3    Palen, D.I.4    Matrougui, K.5
  • 64
    • 67650507015 scopus 로고    scopus 로고
    • Association between familial mediterranean fever and retroperitoneal fibrosis: Retroperitoneal fibrosis regression after colchicine therapy
    • De SG, Cerquaglia C, Curigliano V, et al. Association between familial mediterranean fever and retroperitoneal fibrosis: retroperitoneal fibrosis regression after colchicine therapy. Int J Immunopathol Pharmacol 2009; 22: 521-4.
    • (2009) Int J Immunopathol Pharmacol , vol.22 , pp. 521-524
    • De, S.G.1    Cerquaglia, C.2    Curigliano, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.