Systemic administration of a deoxyribozyme to xylosyltransferase-1 mRNA promotes recovery after a spinal cord contusion injury

Experimental Neurology

Volumn 237, Issue 1, 2012, Pages 170-179

  Oudega, Martin ^a,b,e   Chao, Owen Y ^a   Avison, Donna L ^a   Bronson, Roderick T ^b   Buchser, William J ^c   Hurtado, Andres ^d   Grimpe, Barbara ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d Dana Faber/Harvard Cancer Center   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chondroitin sulfate proteoglycans; DNA enzyme; Functional recovery; Glial scar; Neurotherapeutics; Regeneration; Spinal cord injury

Indexed keywords

DEOXYRIBOZYME; MESSENGER RNA; TRANSFERASE; UNCLASSIFIED DRUG; XYLOSYLTRANSFERASE 1;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOTINYLATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; FEMALE; IMMUNOHISTOCHEMISTRY; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; NERVE REGENERATION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; QUALITY OF LIFE; RAT; SENSORIMOTOR FUNCTION; SEROTONINERGIC SYSTEM; SPINAL CORD INJURY; STEREOTACTIC TREATMENT;

ANIMALS; DNA, CATALYTIC; FEMALE; INJECTIONS, INTRAVENOUS; PENTOSYLTRANSFERASES; RATS; RATS, INBRED F344; RECOVERY OF FUNCTION; RNA, MESSENGER; SPINAL CORD INJURIES;

EID: 84863814693     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.06.006     Document Type: Article

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