Animal models used in spinal cord regeneration research

Spine

Volumn 27, Issue 14, 2002, Pages 1504-1510

  Kwon, Brian K ^a   Oxland, Tom R ^a   Tetzlaff, Wolfram ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Animal models; Spinal cord contusion models; Spinal cord regeneration; Spinal cord transection models

Indexed keywords

ANATOMY; ANIMAL MODEL; ARTICLE; HISTOLOGY; MEDICAL RESEARCH; MOTOR PERFORMANCE; NEUROPHYSIOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SENSORIMOTOR FUNCTION; SPINAL CORD; SPINAL CORD INJURY; SPINAL CORD TRANSSECTION; TISSUE REGENERATION;

ANIMALS; DISEASE MODELS, ANIMAL; NERVE REGENERATION; RESEARCH; SPINAL CORD; SPINAL CORD COMPRESSION; SPINAL CORD INJURIES;

EID: 0037099667     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-200207150-00005     Document Type: Article

References (68)

1. Mechanisms of secondary injury to spinal cord axons in vitro: Role of Na+, Na(+)-K(+)-ATPase, the Na(+)-H+ exchanger, and the Na(+)-Ca2+ exchanger
2. Role of NMDA and non-NMDA ionotropic glutamate receptors in traumatic spinal cord axonal injury
3. Role of L- and N-type calcium channels in the pathophysiology of traumatic spinal cord white matter injury
4. Differential labeling of converging afferent pathways using biotinylated dextran amine and cholera toxin subunit B
5. Surgery of experimental lesion of spinal cord equivalent to crush injury of fracture dislocation of spinal column
6. Experimental models for spinal cord injury research: Physical and physiological considerations
7. Tapping into spinal circuits to restore motor function
8. A sensitive and reliable locomotor rating scale for open field testing in rats
9. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
10. MASCIS evaluation of open field locomotor scores: Effects of experience and teamwork on reliability. Multicenter Animal Spinal Cord Injury Study
11. A comparison of treadmill locomotion in adult cats before and after spinal transection
12. Spinal cord injury models: Neurophysiology
13. Three-dimensional computer-assisted analysis of graded contusion lesions in the spinal cord of the rat
14. A behavioral and anatomical analysis of spinal cord injury produced by a feedback-controlled impaction device
15. Rubrospinal projections in the rat
16. Observations on the pathology of human spinal cord injury: A review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination
17. Early locomotor training with clonidine in spinal cats
18. Effects of intrathecal alpha 1- and alpha 2-noradrenergic agonists and norepinephrine on locomotion in chronic spinal cats
19. Gait analysis of adult paraplegic rats after spinal cord repair
20. Spinal cord repair in adult paraplegic rats: Partial restoration of hind limb function
21. The emergence of modern neuroanatomy and developmental neurobiology
22. Full weight-bearing hindlimb standing following stand training in the adult spinal cat
23. Locomotor capacity attributable to step training versus spontaneous recovery after spinalization in adult cats
24. Spinal cord deformation velocity, impulse, and energy related to lesion volume in "standardized" trauma
25. Experimental treatments of acute spinal cord injury
26. Changes in pharmacological sensitivity of the spinal cord to potassium channel blockers following acute spinal cord injury
27. The effect of direct current field polarity on recovery after acute experimental spinal cord injury
28. The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury
29. The relationships among the severity of spinal cord injury, motor and somatosensory evoked potentials, and spinal cord blood flow
30. Experimental studies on spinal cord injuries in the last fifteen years
31. A reproducible spinal cord injury model in the cat
32. Neuroprotective effects of a novel NMDA antagonist, Gacyclidine, after experimental contusive spinal cord injury in adult rats
33. Spinal cord blood flow after acute experimental cord injury in dogs
34. A monitored contusion model of spinal cord injury in the rat
35. Decompression of the spinal cord improves recovery after acute experimental spinal cord compression injury
36. Development of posttraumatic cysts in the spinal cord of rats subjected to severe spinal cord contusion
37. Neuropathology of human spinal cord injury sustained in sports-related activities
38. Motor-sensory cortex-corticospinal system and developing locomotion and placing in rats
39. External anal sphincter hyperreflexia following spinal transection in the rat
40. Transplantation of olfactory ensheathing cells or Schwann cells restores rapid and secure conduction across the transected spinal cord
41. Traumatic spinal cord injury produced by controlled contusion in mouse
42. Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury
43. Neurotrophic factors, cellular bridges, and gene therapy for spinal cord injury
44. The applied neuropathology of human spinal cord injury
45. Pathology of injuries of the vertebral column and spinal cord
46. Interaction of contact velocity and cord compression in determining the severity of spinal cord injury
47. BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration
48. Possible mechanisms for observed pathophysiological variability in experimental spinal cord injury by the method of Allen
49. Methods to assess the development and recovery of locomotor function after spinal cord injury in rats
50. Validation of the weight-drop contusion model in rats: A comparative study of human spinal cord injury
51. Analysis and measurement of some sources of variability in experimental spinal cord trauma
52. Red nucleus lesions impair overground locomotion in rats: A kinetic analysis
53. Spinal cord contusion in the rat: Morphometric analyses of alterations in the spinal cord
54. Correlation between parameters of spinal cord impact and resultant injury
55. Electromechanical impactor for producing experimental spinal cord injury in animals
56. Conduction of impulses by axons regenerated in a Schwann cell graft in the transected adult rat thoracic spinal cord
57. Progress in spinal cord research: A refined strategy for the International Spinal Research Trust
58. Objective clinical assessment of motor function after experimental spinal cord injury in the rat
59. Effect of duration of acute spinal cord compression in a new acute cord injury model in the rat
60. Locomotion and its recovery after spinal injury
61. Locomotor performance and adaptation after partial or complete spinal cord lesions in the cat
62. Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: Improved behavioral and neuroanatomical recovery with riluzole
63. Ladder beam and camera video recording system for evaluating forelimb and hindlimb deficits after sensorimotor cortex injury in rats
64. Experimental spinal cord injury: A dynamic and verifiable injury device
65. Anatomy and pathophysiology of spinal cord injury
66. The experimental contusion injury of the spinal cord in sheep
67. Molecular and cellular mechanisms of spinal cord injury therapies
68. Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats