Hypothalamic Regulation of Anterior Pituitary Function

The Pituitary

Volumn , Issue , 2011, Pages 21-45

  Ben Shlomo, Anat ^a   Melmed, Shlomo ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84863793706     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-380926-1.10002-1     Document Type: Chapter

References (164)

1. Sawin C.T. Berta and Ernst Scharrer and the concept of neurosecretion. The Endocrinologist 2003, 13:73-75.
2. Klavdieva M.M. The history of neuropeptides 1. Front Neuroendocrinol 1995, 16:293-321.
3. Harris G.W. Neural control of the pituitary gland. I. The neurohypophysis. Br Med J 1951, 2:559-564.
4. Scharrer E. Neurosecretion. X. A relationship between the paraphysis and the paraventricular nucleus in the garter snake (Thamnophis sp.). Biological bulletin 1951, 101:106-113.
5. Berkeley H.J. The finer anatomy of the infundibular region of the cerebrum including the pituitary gland. Brain 1894, 17:515-547.
6. Popa G.T., Fielding U. Hypophysio-portal vessels and their colloid accompaniment. J Anat 1933, 67:221. 227-232.
7. Harris G.W. Electrical stimulation of the hypothalamus and the mechanism of neural control of the adenohypophysis. J Physiol 1948, 107:418-429.
8. Guillemin R. 2008 Somatostatin: The beginnings. Mol Cell Endocrinol 1972, 286:3-4.
9. Schally A.V., Saffran M., Zimmermann B. A corticotrophin-releasing factor: Partial purification and amino acid composition. Biochem J 1958, 70:97-103.
10. Sheehan H.L., Kovacs K. Neurohypophysis and hypothalamus. Endocrine Pathology, General and Surgical 1982, 45-99. Williams & Wilkins, Baltimore. J.M.B. Bloodworth (Ed.).
11. Scheithauer B.W. The hypothalamus and neurohypophysis. Functional Endocrine Pathology 1991, 171-296. Blackwell Science, Boston. second ed. K. Kovacs, S.L. Asa (Eds.).
12. Ambach G., Palkovits M., Szentagothai J. Blood supply of the rat hypothalamus. IV. Retrochiasmatic area, median eminence, arcuate nucleus. Acta Morphol Acad Sci Hung 1976, 24:93-119.
13. Broadwell R.D., Balin B.J., Salcman M., Kaplan R.S. Brain-blood barrier? Yes and no. Proc Nat Acad Sci USA 1983, 80:7352-7356.
14. Page R.B. The anatomy of the hypothalamo-hypophyseal complex. The Physiology of Reproduction 1988, 1161-1233. Raven Press, New York. E. Knobil, J. Neill, L.L. Ewing, G.S. Greenwald, C.L. Markert, D.W. Pfaff (Eds.).
15. Knigge K.M., Scott D.E. Structure and function of the median eminence. Am J Anat 1970, 129:223-243.
16. Rodriguez E.M., Blazquez J.L., Pastor F.E., Pelaez B., Pena P., Peruzzo B., et al. Hypothalamic tanycytes: A key component of brain-endocrine interaction. Int Rev Cytol 2005, 247:89-164.
17. Clarke I., Jessop D., Millar R., Morris M., Bloom S., Lightman S., et al. Many peptides that are present in the external zone of the median eminence are not secreted into the hypophysial portal blood of sheep. Neuroendocrinology 1993, 57:765-775.
18. Page R.B. Pituitary blood flow. Am J Physiol 1982, 243:E427-442.
19. Begley D.J., Brightman M.W. Structural and functional aspects of the blood-brain barrier. Prog Drug Res 2003, 61:39-78.
20. Shaver S.W., Pang J.J., Wainman D.S., Wall K.M., Gross P.M. Morphology and function of capillary networks in subregions of the rat tuber cinereum. Cell Tissue Res 1992, 267:437-448.
21. Ciofi P., Garret M., Lapirot O., Lafon P., Loyens A., Prevot V., et al. Brain-endocrine interactions: A microvascular route in the mediobasal hypothalamus. Endocrinology 2009, 150:5509-5519.
22. Hatton G.I., Perlmutter L.S., Salm A.K., Tweedle C.D. Dynamic neuronal-glial interactions in hypothalamus and pituitary: Implications for control of hormone synthesis and release. Peptides 1984, 5(Suppl 1):121-138.
23. Ojeda S.R., Lomniczi A., Sandau U.S. Glial-gonadotrophin hormone (GnRH) neurone interactions in the median eminence and the control of GnRH secretion. J Neuroendocrinol 2008, 20:732-742.
24. Asa S.L. Tumors of the pituitary gland. Atlas of tumor pathology, Fascicle 22, Third series 1998, Armed Forces Institute of Pathology, Washington DC.
25. Horvath E., Kovacs K. Fine structural cytology of the adenohypophysis in rat and man. J Electron Microsc Tech 1988, 8:401-432.
26. Morgan P.J., Williams L.M. The pars tuberalis of the pituitary: A gateway for neuroendocrine output. Rev Reprod 1996, 1:153-161.
27. Horvath E., Kovacs K., Penz G., Ezrin C. Origin, possible function and fate of "follicular cells" in the anterior lobe of the human pituitary. Am J Pathol 1974, 77:199-212.
28. Girod C., Trouillas J., Dubois M.P. Immunocytochemical localization of S-100 protein in stellate cells (folliculo-stellate cells) of the anterior lobe of the normal human pituitary. Cell Tissue Res 1985, 241:505-511.
29. Hofler H., Walter G.F., Denk H. Immunohistochemistry of folliculo-stellate cells in normal human adenohypophyses and in pituitary adenomas. Acta Neuropathol 1984, 65:35-40.
30. Kovacs K., Horvath E., Ryan N., Ezrin C. Null cell adenoma of the human pituitary. Virchows Arch A Pathol Anat Histol 1980, 387:165-174.
31. Dyess E.M., Segerson T.P., Liposits Z., Paull W.K., Kaplan M.M., Wu P., et al. Triiodothyronine exerts direct cell-specific regulation of thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus. Endocrinology 1988, 123:2291-2297.
32. Yamada M., Radovick S., Wondisford F.E., Nakayama Y., Weintraub B.D., Wilber J.F. Cloning and structure of human genomic DNA and hypothalamic cDNA encoding human prepro-thyrotropin-releasing hormone. Mol Endocrinol 1990, 4:551-556.
33. Perello M., Nillni E.A. The biosynthesis and processing of neuropeptides: Lessons from prothyrotropin releasing hormone (proTRH). Front Biosci 2007, 12:3554-3565.
34. Sun Y., Lu X., Gershengorn M.C. Thyrotropin-releasing hormone receptors - similarities and differences. J Mol Endocrinol 2003, 30:87-97.
35. Mori M., Yamada M., Kobayashi S. Role of the hypothalamic TRH in the regulation of its own receptors in rat anterior pituitaries. Neuroendocrinology 1988, 48:153-159.
36. Faglia G. The clinical impact of the thyrotropin-releasing hormone test. Thyroid 1998, 8:903-908.
37. Hartnell J.M., Pekary A.E., Hershman J.M. Comparison of the effects of pulsatile and continuous TRH infusion on TSH release in men. Metabolism 1987, 36:878-882.
38. Chiamolera M.I., Wondisford F.E. Minireview: Thyrotropin-releasing hormone and the thyroid hormone feedback mechanism. Endocrinology 2009, 150:1091-1096.
39. Weeke J. The response of thyrotropin and triiodothyronine to various doses of thyrotropin releasing hormone in normal man. Eur J Clin Invest 1975, 5:447-453.
40. Jackson I.M. Thyrotropin-releasing hormone. N Engl J Med 1982, 306:145-155.
41. Yamada M., Shibusawa N., Ishii S., Horiguchi K., Umezawa R., Hashimoto K., et al. Prolactin secretion in mice with thyrotropin-releasing hormone deficiency. Endocrinology 2006, 147:2591-2596.
42. Lechan R.M., Fekete C. Role of thyroid hormone deiodination in the hypothalamus. Thyroid 2005, 15:883-897.
43. Fekete C., Lechan R.M. Negative feedback regulation of hypophysiotropic thyrotropin-releasing hormone (TRH) synthesizing neurons: Role of neuronal afferents and type 2 deiodinase. Front Neuroendocrinol 2007, 28:97-114.
44. Hollenberg A.N., Monden T., Flynn T.R., Boers M.E., Cohen O., Wondisford F.E. The human thyrotropin-releasing hormone gene is regulated by thyroid hormone through two distinct classes of negative thyroid hormone response elements. Mol Endocrinol 1995, 9:540-550.
45. Shupnik M.A., Chin W.W., Habener J.F., Ridgway E.C. Transcriptional regulation of the thyrotropin subunit genes by thyroid hormone. J Biol Chem 1985, 260:2900-2903.
46. Shupnik M.A., Ridgway E.C. Triiodothyronine rapidly decreases transcription of the thyrotropin subunit genes in thyrotropic tumor explants. Endocrinology 1985, 117:1940-1946.
47. Dahl G.E., Evans N.P., Thrun L.A., Karsch F.J. A central negative feedback action of thyroid hormones on thyrotropin-releasing hormone secretion. Endocrinology 1994, 135:2392-2397.
48. Drouin J., De Lean A., Rainville D., Lachance R., Labrie F. Characteristics of the interaction between thyrotropin-releasing hormone and somatostatin for thyrotropin and prolactin release. Endocrinology 1976, 98:514-521.
49. Rodriguez F., Jolin T. The role of somatostatin and/or dopamine in basal and TRH-stimulated TSH release in food-restricted rats. Acta Endocrinol (Copenh) 1991, 125:186-191.
50. Nicoletti I., Filipponi P., Fedeli L., Ambrosi F., Giammartino C., Spinozzi F., et al. Catecholamines and pituitary function. IV. Effects of low-dose dopamine infusion and long-term bromocriptine treatment on the abnormal thyrotroph (TSH) dynamics in patients with pathological hyperprolactinaemia. Acta Endocrinol (Copenh) 1986, 111:154-161.
51. Lechan R.M., Fekete C. Feedback regulation of thyrotropin-releasing hormone (TRH): Mechanisms for the non-thyroidal illness syndrome. J Endocrinol Invest 2004, 27:105-119.
52. Ahima R.S., Prabakaran D., Mantzoros C., Qu D., Lowell B., Maratos-Flier E., et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996, 382:250-252.
53. Lovejoy D.A. Structural evolution of urotensin-I: Reflections of life before corticotropin releasing factor. Gen Comp Endocrinol 2009, 164:15-19.
54. Aguilera G., Nikodemova M., Wynn P.C., Catt K.J. Corticotropin releasing hormone receptors: Two decades later. Peptides 2004, 25:319-329.
55. Watts A.G. Glucocorticoid regulation of peptide genes in neuroendocrine CRH neurons: A complexity beyond negative feedback. Front Neuroendocrinol 2005, 26:109-130.
56. Shibahara S., Morimoto Y., Furutani Y., Notake M., Takahashi H., Shimizu S., et al. Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene. EMBO J 1983, 2:775-779.
57. Tsatsanis C., Dermitzaki E., Venihaki M., Chatzaki E., Minas V., Gravanis A., et al. The corticotropin-releasing factor (CRF) family of peptides as local modulators of adrenal function. Cell Mol Life Sci 2007, 64:1638-1655.
58. Gysling K., Forray M.I., Haeger P., Daza C., Rojas R. Corticotropin-releasing hormone and urocortin: Redundant or distinctive functions?. Brain Res Brain Res Rev 2004, 47:116-125.
59. Gutknecht E., Van der Linden I., Van Kolen K., Verhoeven K.F., Vauquelin G., Dautzenberg F.M. Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling. Mol Pharmacol 2009, 75:648-657.
60. Gold P.W., Loriaux D.L., Roy A., Kling M.A., Calabrese J.R., Kellner C.H., et al. Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease. Pathophysiologic and diagnostic implications. N Engl J Med 1986, 314:1329-1335.
61. Davis M.E., Pemberton C.J., Yandle T.G., Lainchbury J.G., Rademaker M.T., Nicholls M.G., et al. Urocortin-1 infusion in normal humans. J Clin Endocrinol Metab 2004, 89:1402-1409.
62. Kling M.A., DeBellis M.D., O'Rourke D.K., Listwak S.J., Geracioti T.D., McCutcheon I.E., et al. Diurnal variation of cerebrospinal fluid immunoreactive corticotropin-releasing hormone levels in healthy volunteers. J Clin Endocrinol Metab 1994, 79:233-239.
63. Muglia L.J., Jacobson L., Weninger S.C., Luedke C.E., Bae D.S., Jeong K.H., et al. Impaired diurnal adrenal rhythmicity restored by constant infusion of corticotropin-releasing hormone in corticotropin-releasing hormone-deficient mice. J Clin Invest 1997, 99:2923-2929.
64. Muglia L., Jacobson L., Dikkes P., Majzoub J.A. Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature 1995, 373:427-432.
65. Sawchenko P.E., Li H.Y., Ericsson A. Circuits and mechanisms governing hypothalamic responses to stress: A tale of two paradigms. Prog Brain Res 2000, 122:61-78.
66. Herman J.P., Figueiredo H., Mueller N.K., Ulrich-Lai Y., Ostrander M.M., Choi D.C., et al. Central mechanisms of stress integration: Hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. Front Neuroendocrinol 2003, 24:151-180.
67. Reichlin S. Neuroendocrinology of infection and the innate immune system. Recent Prog Horm Res 1999, 54:133-181. discussion 181-183.
68. Besedovsky H., del Rey A., Sorkin E., Dinarello C.A. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 1986, 233:652-654.
69. Berczi I., Quintanar-Stephano A., Kovacs K. Neuroimmune regulation in immunocompetence, acute illness, and healing. Ann NY Acad Sci 2009, 1153:220-239.
70. Durand D., Pampillo M., Caruso C., Lasaga M. Role of metabotropic glutamate receptors in the control of neuroendocrine function. Neuropharmacology 2008, 55:577-583.
71. Kovacs K.J., Miklos I.H., Bali B. GABAergic mechanisms constraining the activity of the hypothalamo-pituitary-adrenocortical axis. Ann NY Acad Sci 2004, 1018:466-476.
72. Schwartz M.W., Seeley R.J., Campfield L.A., Burn P., Baskin D.G. Identification of targets of leptin action in rat hypothalamus. J Clin Invest 1996, 98:1101-1106.
73. Jang M., Mistry A., Swick A.G., Romsos D.R. Leptin rapidly inhibits hypothalamic neuropeptide Y secretion and stimulates corticotropin-releasing hormone secretion in adrenalectomized mice. J Nutr 2000, 130:2813-2820.
74. Liao N., Vaudry H., Pelletier G. Neuroanatomical connections between corticotropin-releasing factor (CRF) and somatostatin (SRIF) nerve endings and thyrotropin-releasing hormone (TRH) neurons in the paraventricular nucleus of rat hypothalamus. Peptides 1992, 13:677-680.
75. Wang X.M., Tresham J.J., Coghlan J.P., Scoggins B.A. Intracerebroventricular infusion of a cyclic hexapeptide analogue of somatostatin inhibits hemorrhage-induced ACTH release. Neuroendocrinology 1987, 45:325-327.
76. Patel Y.C. Somatostatin and its receptor family. Front Neuroendocrinol 1999, 20:157-198.
77. Szafarczyk A., Guillaume V., Conte-Devolx B., Alonso G., Malaval F., Pares-Herbute N., et al. Central catecholaminergic system stimulates secretion of CRH at different sites. Am J Physiol 1988, 255:E463-468.
78. Eaton M.J., Cheung S., Moore K.E., Lookingland K.J. Dopamine receptor-mediated regulation of corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Brain Res 1996, 738:60-66.
79. Cowley M.A., Smith R.G., Diano S., Tschop M., Pronchuk N., Grove K.L., et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 2003, 37:649-661.
80. Reichlin S. Thyroid function, body temperature regulation and growth in rats with hypothalamic lesions. Endocrinology 1960, 66:340-354.
81. Deuben R.R., Meites J. Stimulation of pituitary growth hormone release by a hypothalamic extract in vitro. Endocrinology 1964, 74:408-414.
82. Antony G.J., Van Wyk J.J., French F.S., Weaver R.P., Dugger G.S., Timmons R.L., et al. Influence of pituitary stalk section on growth hormone, insulin and TSH secretion in women with metastatic breast cancer. J Clin Endocrinol Metab 1969, 29:1238-1250.
83. Hunter W.M., Friend J.A., Strong J.A. The diurnal pattern of plasma growth hormone concentration in adults. J Endocrinol 1966, 34:139-146.
84. Greenwood F.C., Landon J. Growth hormone secretion in response to stress in man. Nature 1966, 210:540-541.
85. Brazeau P., Vale W., Burgus R., Ling N., Butcher M., Rivier J., et al. Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science 1973, 179:77-79.
86. Rivier J., Spiess J., Thorner M., Vale W. Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour. Nature 1982, 300:276-278.
87. Mayo K.E., Vale W., Rivier J., Rosenfeld M.G., Evans R.M. Expression-cloning and sequence of a cDNA encoding human growth hormone-releasing factor. Nature 1983, 306:86-88.
88. Bloch B., Gaillard R.C., Brazeau P., Lin H.D., Ling N. Topographical and ontogenetic study of the neurons producing growth hormone-releasing factor in human hypothalamus. Regul Pept 1984, 8:21-31.
89. Lin-Su K., Wajnrajch M.P. Growth hormone releasing hormone (GHRH) and the GHRH receptor. Rev Endocr Metab Disord 2002, 3:313-323.
90. Chowen J.A., Frago L.M., Argente J. The regulation of GH secretion by sex steroids. Eur J Endocrinol 2004, 151(Suppl 3):U95-100.
91. Frohman L.A., Downs T.R., Heimer E.P., Felix A.M. Dipeptidylpeptidase IV and trypsin-like enzymatic degradation of human growth hormone-releasing hormone in plasma. J Clin Invest 1989, 83:1533-1540.
92. Frohman L.A., Downs T.R., Chomczynski P., Frohman M.A. Growth hormone-releasing hormone: Structure, gene expression and molecular heterogeneity. Acta Paediatr Scand Suppl 1990, 367:81-86.
93. Mayo K.E., Godfrey P.A., Suhr S.T., Kulik D.J., Rahal J.O. Growth hormone-releasing hormone: Synthesis and signaling. Recent Prog Horm Res 1995, 50:35-73.
94. Pombo C.M., Zalvide J., Gaylinn B.D., Dieguez C. Growth hormone-releasing hormone stimulates mitogen-activated protein kinase. Endocrinology 2000, 141:2113-2119.
95. Giustina A., Veldhuis J.D. Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human. Endocr Rev 1998, 19:717-797.
96. Vance M.L., Kaiser D.L., Rivier J., Vale W., Thorner M.O. Dual effects of growth hormone (GH)-releasing hormone infusion in normal men: Somatotroph desensitization and increase in releasable GH. J Clin Endocrinol Metab 1986, 62:591-594.
97. Frohman L.A., Kineman R.D. Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis. Trends Endocrinol Metab 2002, 13:299-303.
98. Muller E.E., Locatelli V., Cocchi D. Neuroendocrine control of growth hormone secretion. Physiol Rev 1999, 79:511-607.
99. Fodor M., Kordon C., Epelbaum J. Anatomy of the hypophysiotropic somatostatinergic and growth hormone-releasing hormone system minireview. Neurochem Res 2006, 31:137-143.
100. Torsello A., Panzeri G., Cermenati P., Caroleo M.C., Ghigo E., Camanni F., et al. Involvement of the somatostatin and cholinergic systems in the mechanism of growth hormone autofeedback regulation in the rat. J Endocrinol 1988, 117:273-281.
101. Zheng H., Bailey A., Jiang M.H., Honda K., Chen H.Y., Trumbauer M.E., et al. Somatostatin receptor subtype 2 knockout mice are refractory to growth hormone-negative feedback on arcuate neurons. Mol Endocrinol 1997, 11:1709-1717.
102. Yamashita S., Weiss M., Melmed S. Insulin-like growth factor I regulates growth hormone secretion and messenger ribonucleic acid levels in human pituitary tumor cells. J Clin Endocrinol Metab 1986, 63:730-735.
103. Aguado F., Rodrigo J., Cacicedo L., Mellstrom B. Distribution of insulin-like growth factor-I receptor mRNA in rat brain. Regulation in the hypothalamo-neurohypophysial system. J Mol Endocrinol 1993, 11:231-239.
104. Garcia-Segura L.M., Rodriguez J.R., Torres-Aleman I. Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: An electron microscopic study. J Neurocytol 1997, 26:479-490.
105. Melmed S. Insulin-like growth factor I - a prototypic peripheral-paracrine hormone?. Endocrinology 1999, 140:3879-3880.
106. Becker K., Stegenga S., Conway S. Role of insulin-like growth factor I in regulating growth hormone release and feedback in the male rat. Neuroendocrinology 1995, 61:573-583.
107. Gautam D., Jeon J., Starost M.F., Han S.J., Hamdan F.F., Cui Y., et al. Neuronal M3 muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth. Proc Nat Acad Sci USA 2009, 106:6398-6403.
108. Mechenthaler I. Galanin and the neuroendocrine axes. Cell Mol Life Sci 2008, 65:1826-1835.
109. Hulting A.L., Meister B., Carlsson L., Hilding A., Isaksson O. On the role of the peptide galanin in regulation of growth hormone secretion. Acta Endocrinol (Copenh) 1991, 125:518-525.
110. Kojima M., Kangawa K. Ghrelin: Structure and function. Physiol Rev 2005, 85:495-522.
111. Danger J.M., Tonon M.C., Jenks B.G., Saint-Pierre S., Martel J.C., Fasolo A., et al. Neuropeptide Y: Localization in the central nervous system and neuroendocrine functions. Fundam Clin Pharmacol 1990, 4:307-340.
112. Bluet-Pajot M.T., Epelbaum J., Gourdji D., Hammond C., Kordon C. Hypothalamic and hypophyseal regulation of growth hormone secretion. Cell Mol Neurobiol 1998, 18:101-123.
113. Wagner C., Caplan S.R., Tannenbaum G.S. Interactions of ghrelin signaling pathways with the GH neuroendocrine axis: A new and experimentally tested model. J Mol Endocrinol 2009, 43:105-119.
114. Lee V.H., Lee L.T., Chow B.K. Gonadotropin-releasing hormone: Regulation of the GnRH gene. FEBS J 2008, 275:5458-5478.
115. Conn P.M., Crowley W.F. Gonadotropin-releasing hormone and its analogues. N Engl J Med 1991, 324:93-103.
116. Krsmanovic L.Z., Hu L., Leung P.K., Feng H., Catt K.J. The hypothalamic GnRH pulse generator: Multiple regulatory mechanisms. Trends Endocrinol Metab 2009, 20:402-408.
117. Cheng C.K., Leung P.C. Molecular biology of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and their receptors in humans. Endocr Rev 2005, 26:283-306.
118. Whitlock K.E. Origin and development of GnRH neurons. Trends Endocrinol Metab 2005, 16:145-151.
119. Naor Z. Signaling by G-protein-coupled receptor (GPCR): Studies on the GnRH receptor. Front Neuroendocrinol 2009, 30:10-29.
120. Clayton R.N. Mechanism of GnRH action in gonadotrophs. Hum Reprod 1988, 3:479-483.
121. Conn P.M., Crowley W.F. Gonadotropin-releasing hormone and its analogs. Annu Rev Med 1994, 45:391-405.
122. Rispoli L.A., Nett T.M. Pituitary gonadotropin-releasing hormone (GnRH) receptor: Structure, distribution and regulation of expression. Anim Reprod Sci 2005, 88:57-74.
123. Martinez de la Escalera G., Choi A.L., Weiner R.I. Generation and synchronization of gonadotropin-releasing hormone (GnRH) pulses: Intrinsic properties of the GT1-1 GnRH neuronal cell line. Proc Nat Acad Sci USA 1992, 89:1852-1855.
124. Wildt L., Hausler A., Marshall G., Hutchison J.S., Plant T.M., Belchetz P.E., et al. Frequency and amplitude of gonadotropin-releasing hormone stimulation and gonadotropin secretion in the rhesus monkey. Endocrinology 1981, 109:376-385.
125. Chappel S.C., Ulloa-Aguirre A., Coutifaris C. Biosynthesis and secretion of follicle-stimulating hormone. Endocr Rev 1983, 4:179-211.
126. Seminara S.B. Metastin and its G protein-coupled receptor, GPR54: Critical pathway modulating GnRH secretion. Front Neuroendocrinol 2005, 26:131-138.
127. Dungan H.M., Clifton D.K., Steiner R.A. Minireview: Kisspeptin neurons as central processors in the regulation of gonadotropin-releasing hormone secretion. Endocrinology 2006, 147:1154-1158.
128. Uenoyama Y., Tsukamura H., Kinoshita M., Yamada S., Iwata K., Pheng V., et al. Oestrogen-dependent stimulation of luteinising hormone release by galanin-like peptide in female rats. J Neuroendocrinol 2008, 20:626-631.
129. Gundlach A.L. Galanin/GALP and galanin receptors: Role in central control of feeding, body weight/obesity and reproduction?. Eur J Pharmacol 2002, 440:255-268.
130. Crown A., Clifton D.K., Steiner R.A. Neuropeptide signaling in the integration of metabolism and reproduction. Neuroendocrinology 2007, 86:175-182.
131. Shughrue P., Scrimo P., Lane M., Askew R., Merchenthaler I. The distribution of estrogen receptor-beta mRNA in forebrain regions of the estrogen receptor-alpha knockout mouse. Endocrinology 1997, 138:5649-5652.
132. Bethea C.L., Brown N.A., Kohama S.G. Steroid regulation of estrogen and progestin receptor messenger ribonucleic acid in monkey hypothalamus and pituitary. Endocrinology 1996, 137:4372-4383.
133. Simerly R.B., Chang C., Muramatsu M., Swanson L.W. Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study. J Comp Neurol 1990, 294:76-95.
134. Hu L., Gustofson R.L., Feng H., Leung P.K., Mores N., Krsmanovic L.Z., et al. Converse regulatory functions of estrogen receptor-alpha and -beta subtypes expressed in hypothalamic gonadotropin-releasing hormone neurons. Mol Endocrinol 2008, 22:2250-2259.
135. Plant T.M. Gonadal regulation of hypothalamic gonadotropin-releasing hormone release in primates. Endocr Rev 1986, 7:75-88.
136. Smith M.J., Jennes L. Neural signals that regulate GnRH neurones directly during the oestrous cycle. Reproduction 2001, 122:1-10.
137. Brann D.W., Mahesh V.B. Excitatory amino acids: Function and significance in reproduction and neuroendocrine regulation. Front Neuroendocrinol 1994, 15:3-49.
138. Smith J.T., Clarke I.J. Gonadotropin inhibitory hormone function in mammals. Trends Endocrinol Metab 2010.
139. Plant T.M. Neurobiological bases underlying the control of the onset of puberty in the rhesus monkey: A representative higher primate. Front Neuroendocrinol 2001, 22:107-139.
140. Cameron J.L. Stress and behaviorally induced reproductive dysfunction in primates. Semin Reprod Endocrinol 1997, 15:37-45.
141. Breen K.M., Karsch F.J. New insights regarding glucocorticoids, stress and gonadotropin suppression. Front Neuroendocrinol 2006, 27:233-245.
142. Dobson H., Ghuman S., Prabhakar S., Smith R. A conceptual model of the influence of stress on female reproduction. Reproduction 2003, 125:151-163.
143. Bilezikjian L.M., Blount A.L., Donaldson C.J., Vale W.W. Pituitary actions of ligands of the TGF-beta family: Activins and inhibins. Reproduction 2006, 132:207-215.
144. Ben-Shlomo A., Melmed S. Pituitary somatostatin receptor signaling. Trends Endocrinol Metab 2010, 21:123-133.
145. Patel Y.C., Srikant C.B. Somatostatin mediation of adenohypophysial secretion. Annu Rev Physiol 1986, 48:551-567.
146. Ross R.J., Tsagarakis S., Grossman A., Nhagafoong L., Touzel R.J., Rees L.H., et al. GH feedback occurs through modulation of hypothalamic somatostatin under cholinergic control: Studies with pyridostigmine and GHRH. Clin Endocrinol (Oxf) 1987, 27:727-733.
147. Ben-Shlomo A., Melmed S. Pituitary somatostatin receptor signaling. Trends Endocrinol Metab 2010, 123-133.
148. Freeman M.E., Kanyicska B., Lerant A., Nagy G. Prolactin: Structure, function, and regulation of secretion. Physiol Rev 2000, 80:1523-1631.
149. Lerant A., Herman M.E., Freeman M.E. Dopaminergic neurons of periventricular and arcuate nuclei of pseudopregnant rats: Semicircadian rhythm in Fos-related antigens immunoreactivities and in dopamine concentration. Endocrinology 1996, 137:3621-3628.
150. Chronwall B.M., Millington W.R., Griffin W.S., Unnerstall J.R., O'Donohue T.L. Histological evaluation of the dopaminergic regulation of proopiomelanocortin gene expression in the intermediate lobe of the rat pituitary, involving in situ hybridization and [3H]thymidine uptake measurement. Endocrinology 1987, 120:1201-1211.
151. Lindley S.E., Gunnet J.W., Lookingland K.J., Moore K.E. Effects of alterations in the activity of tuberohypophysial dopaminergic neurons on the secretion of alpha-melanocyte stimulating hormone. Proc Soc Exp Biol Med 1988, 188:282-286.
152. Asa S.L., Kelly M.A., Grandy D.K., Low M.J. Pituitary lactotroph adenomas develop after prolonged lactotroph hyperplasia in dopamine D2 receptor-deficient mice. Endocrinology 1999, 140:5348-5355.
153. Vallar L., Meldolesi J. Mechanisms of signal transduction at the dopamine D2 receptor. Trends Pharmacol Sci 1989, 10:74-77.
154. Suzuki S., Yamamoto I., Arita J. Mitogen-activated protein kinase-dependent stimulation of proliferation of rat lactotrophs in culture by 3',5'-cyclic adenosine monophosphate. Endocrinology 1999, 140:2850-2858.
155. Florio T., Pan M.G., Newman B., Hershberger R.E., Civelli O., Stork P.J. Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatase activity. J Biol Chem 1992, 267:24169-24172.
156. Piercy M., Shin S.H. Comparative studies of prolactin secretion in estradiol-primed and normal male rats induced by ether stress, pimozide and TRH. Neuroendocrinology 1980, 31:270-275.
157. Denef C., Manet D., Dewals R. Dopaminergic stimulation of prolactin release. Nature 1980, 285:243-246.
158. Hill J.B., Nagy G.M., Frawley L.S. Suckling unmasks the stimulatory effect of dopamine on prolactin release: Possible role for alpha-melanocyte-stimulating hormone as a mammotrope responsiveness factor. Endocrinology 1991, 129:843-847.
159. Arey B.J., Burris T.P., Basco P., Freeman M.E. Infusion of dopamine at low concentrations stimulates the release of prolactin from alpha-methyl-p-tyrosine-treated rats. Proc Soc Exp Biol Med 1993, 203:60-63.
160. Milenkovic L., Parlow A.F., McCann S.M. Physiological significance of the negative short-loop feedback of prolactin. Neuroendocrinology 1990, 52:389-392.
161. Arbogast L.A., Voogt J.L. Prolactin (PRL) receptors are colocalized in dopaminergic neurons in fetal hypothalamic cell cultures: Effect of PRL on tyrosine hydroxylase activity. Endocrinology 1997, 138:3016-3023.
162. Toney T.W., Pawsat D.E., Fleckenstein A.E., Lookingland K.J., Moore K.E. Evidence that prolactin mediates the stimulatory effects of estrogen on tuberoinfundibular dopamine neurons in female rats. Neuroendocrinology 1992, 55:282-289.
163. Demarest K.T., Duda N.J., Riegle G.D., Moore K.E. Placental lactogen mimics prolactin in activating tuberoinfundibular dopaminergic neurons. Brain Res 1983, 272:175-178.
164. Molitch M.E. Drugs and prolactin. Pituitary 2008, 11:209-218.