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Volumn 25, Issue 4, 2012, Pages 419-427

Pharmacogenetics in perioperative medicine

Author keywords

analgesia; anesthesia; genetic; pharmacogenetics; pharmacogenomics; polymorphism

Indexed keywords

CELECOXIB; CLOPIDOGREL; CODEINE; DESFLURANE; DIAZEPAM; DRUG METABOLITE; DRUG METABOLIZING ENZYME; FENTANYL; GLUCURONOSYLTRANSFERASE 2B7; HYDROCODONE; HYDROMORPHONE; IBUPROFEN; ISOFLURANE; KETAMINE; METHADONE; MIDAZOLAM; MORPHINE; MORPHINE 3 GLUCURONIDE; MU OPIATE RECEPTOR; OPIATE; OXYCODONE; OXYMORPHONE; PARACETAMOL; PROPOFOL; REMIFENTANIL; SEROTONIN TRANSPORTER; SEVOFLURANE; SUXAMETHONIUM; TRAMADOL; UNINDEXED DRUG;

EID: 84863786412     PISSN: 09527907     EISSN: 14736500     Source Type: Journal    
DOI: 10.1097/ACO.0b013e3283556129     Document Type: Review
Times cited : (50)

References (86)
  • 1
    • 0038209379 scopus 로고    scopus 로고
    • A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine
    • Sawyer MB, Innocenti F, Das S, et al. A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine. Clin Pharmacol Ther 2003; 73:566-574.
    • (2003) Clin. Pharmacol. Ther. , vol.73 , pp. 566-574
    • Sawyer, M.B.1    Innocenti, F.2    Das, S.3
  • 2
    • 40949150784 scopus 로고    scopus 로고
    • Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief
    • Campa D, Gioia A, Tomei A, et al. Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. Clin Pharmacol Ther 2008; 83:559-566.
    • (2008) Clin. Pharmacol. Ther. , vol.83 , pp. 559-566
    • Campa, D.1    Gioia, A.2    Tomei, A.3
  • 3
    • 61349086157 scopus 로고    scopus 로고
    • Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain
    • Rakvag TT, Ross JR, Sato H, et al. Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain. Mol Pain 2008; 4:64.
    • (2008) Mol. Pain , vol.4 , pp. 64
    • Rakvag, T.T.1    Ross, J.R.2    Sato, H.3
  • 4
    • 79251624059 scopus 로고    scopus 로고
    • Combined catechol-O-methyltransferase and mu-opioid receptor gene polymorphisms affect morphine postoperative analgesia and central side effects
    • Kolesnikov Y, Gabovits B, Levin A, et al. Combined catechol-O- methyltransferase and mu-opioid receptor gene polymorphisms affect morphine postoperative analgesia and central side effects. Anesth Analg 2011; 112:448-453.
    • (2011) Anesth. Analg. , vol.112 , pp. 448-453
    • Kolesnikov, Y.1    Gabovits, B.2    Levin, A.3
  • 5
    • 70350620288 scopus 로고    scopus 로고
    • Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment
    • Walter C, Lotsch J. Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment. Pain 2009; 146:270-275.
    • (2009) Pain , vol.146 , pp. 270-275
    • Walter, C.1    Lotsch, J.2
  • 6
    • 67651009389 scopus 로고    scopus 로고
    • Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for postoperative pain
    • Tan EC, Lim EC, Teo YY, et al. Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for postoperative pain. Mol Pain 2009; 5:32.
    • (2009) Mol. Pain , vol.5 , pp. 32
    • Tan, E.C.1    Lim, E.C.2    Teo, Y.Y.3
  • 7
    • 0030041685 scopus 로고    scopus 로고
    • Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation
    • Tateishi T, Krivoruk Y, Ueng YF, et al. Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation. Anesth Analg 1996; 82:167-172.
    • (1996) Anesth. Analg. , vol.82 , pp. 167-172
    • Tateishi, T.1    Krivoruk, Y.2    Ueng, Y.F.3
  • 8
    • 0029813838 scopus 로고    scopus 로고
    • Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes Role of CYP3A4
    • Feierman DE, Lasker JM. Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4. Drug Metab Dispos 1996; 24:932-939.
    • (1996) Drug Metab. Dispos. , vol.24 , pp. 932-939
    • Feierman, D.E.1    Lasker, J.M.2
  • 9
    • 70449685767 scopus 로고    scopus 로고
    • Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery
    • Fukuda K, Hayashida M, Ide S, et al. Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery. Pain 2009; 147:194-201.
    • (2009) Pain , vol.147 , pp. 194-201
    • Fukuda, K.1    Hayashida, M.2    Ide, S.3
  • 10
    • 51549101026 scopus 로고    scopus 로고
    • Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women
    • Landau R, Kern C, Columb MO, et al. Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women. Pain 2008; 139:5-14.
    • (2008) Pain , vol.139 , pp. 5-14
    • Landau, R.1    Kern, C.2    Columb, M.O.3
  • 11
    • 80055014810 scopus 로고    scopus 로고
    • Pharmacological consequence of the A118G mu opioid receptor polymorphism on morphine- and fentanylmediated modulation of Ca 2) channels in humanized mouse sensory neurons
    • Mahmoud S, Thorsell A, Sommer WH, et al. Pharmacological consequence of the A118G mu opioid receptor polymorphism on morphine- and fentanylmediated modulation of Ca(2) channels in humanized mouse sensory neurons. Anesthesiology 2011; 115:1054-1062.
    • (2011) Anesthesiology , Issue.115 , pp. 1054-1062
    • Mahmoud, S.1    Thorsell, A.2    Sommer, W.H.3
  • 12
    • 68449095539 scopus 로고    scopus 로고
    • Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid remifentanil in humans
    • Kosek E, Jensen KB, Lonsdorf TB, et al. Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid remifentanil in humans. Mol Pain 2009; 5:37.
    • (2009) Mol. Pain , vol.5 , pp. 37
    • Kosek, E.1    Jensen, K.B.2    Lonsdorf, T.B.3
  • 13
    • 2442599224 scopus 로고    scopus 로고
    • Role of individual human cytochrome P450 enzymes in the in vitro metabolism of hydromorphone
    • Benetton SA, Borges VM, Chang TK, et al. Role of individual human cytochrome P450 enzymes in the in vitro metabolism of hydromorphone. Xenobiotica 2004; 34:335-344.
    • (2004) Xenobiotica , vol.34 , pp. 335-344
    • Benetton, S.A.1    Borges, V.M.2    Chang, T.K.3
  • 14
    • 0037369176 scopus 로고    scopus 로고
    • Pharmacokinetic drug interactions of morphine, codeine, and their derivatives: Theory and clinical reality
    • Armstrong SC, Cozza KL. Pharmacokinetic drug interactions of morphine, codeine, and their derivatives: Theory and clinical reality. Part I. Psychosomatics 2003; 44:167-171.
    • (2003) Part I. Psychosomatics , vol.44 , pp. 167-171
    • Armstrong, S.C.1    Cozza, K.L.2
  • 15
    • 77955927319 scopus 로고    scopus 로고
    • OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths
    • Bunten H, Liang WJ, Pounder DJ, et al. OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths. Clin Pharmacol Ther 2010; 88:383-389.
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 383-389
    • Bunten, H.1    Liang, W.J.2    Pounder, D.J.3
  • 16
    • 78649967412 scopus 로고    scopus 로고
    • CYP2B6 and OPRM1 gene variations predict methadone-related deaths
    • Bunten H, Liang WJ, Pounder D, et al. CYP2B6 and OPRM1 gene variations predict methadone-related deaths. Addict Biol 2011; 16:142-144.
    • (2011) Addict. Biol. , vol.16 , pp. 142-144
    • Bunten, H.1    Liang, W.J.2    Pounder, D.3
  • 17
    • 4544253622 scopus 로고    scopus 로고
    • Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone
    • Kharasch ED, Hoffer C, Whittington D, et al. Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone. Clin Pharmacol Ther 2004; 76:250-269.
    • (2004) Clin. Pharmacol. Ther. , vol.76 , pp. 250-269
    • Kharasch, E.D.1    Hoffer, C.2    Whittington, D.3
  • 18
    • 79951677547 scopus 로고    scopus 로고
    • Very important pharmacogene summary: Abcb1 (MDR1, P-glycoprotein)
    • Hodges LM, Markova SM, Chinn LW, et al. Very important pharmacogene summary: Abcb1 (MDR1, P-glycoprotein). Pharmacogenet Genomics 2011; 21:152-161.
    • (2011) Pharmacogenet Genomics , vol.21 , pp. 152-161
    • Hodges, L.M.1    Markova, S.M.2    Chinn, L.W.3
  • 19
    • 33646183072 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites
    • Lalovic B, Kharasch E, Hoffer C, et al. Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites. Clin Pharmacol Ther 2006; 79:461-479.
    • (2006) Clin. Pharmacol. Ther. , vol.79 , pp. 461-479
    • Lalovic, B.1    Kharasch, E.2    Hoffer, C.3
  • 20
    • 1842536807 scopus 로고    scopus 로고
    • Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes
    • Lalovic B, Phillips B, Risler LL, et al. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. Drug Metab Dispos 2004; 32:447-454.
    • (2004) Drug Metab. Dispos. , vol.32 , pp. 447-454
    • Lalovic, B.1    Phillips, B.2    Risler, L.L.3
  • 21
    • 1542359666 scopus 로고    scopus 로고
    • CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes
    • Hutchinson MR, Menelaou A, Foster DJ, et al. CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes. Br J Clin Pharmacol 2004; 57:287-297.
    • (2004) Br. J. Clin. Pharmacol. , vol.57 , pp. 287-297
    • Hutchinson, M.R.1    Menelaou, A.2    Foster, D.J.3
  • 22
    • 84855968708 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype
    • Crews KR, Gaedigk A, Dunnenberger HM, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin Pharmacol Ther 2012; 91:321-326.
    • (2012) Clin. Pharmacol. Ther. , Issue.91 , pp. 321-326
    • Crews, K.R.1    Gaedigk, A.2    Dunnenberger, H.M.3
  • 23
    • 51449102329 scopus 로고    scopus 로고
    • Respiratory depression with tramadol in a patient with renal impairment and CYP2D6 gene duplication
    • Stamer UM, Stuber F, Muders T, et al. Respiratory depression with tramadol in a patient with renal impairment and CYP2D6 gene duplication. Anesth Analg 2008; 107:926-929.
    • (2008) Anesth. Analg. , vol.107 , pp. 926-929
    • Stamer, U.M.1    Stuber, F.2    Muders, T.3
  • 24
    • 33750492934 scopus 로고    scopus 로고
    • Effect of the CYP2D6-10 C188T polymorphism on postoperative tramadol analgesia in a Chinese population
    • Wang G, Zhang H, He F, et al. Effect of the CYP2D6-10 C188T polymorphism on postoperative tramadol analgesia in a Chinese population. Eur J Clin Pharmacol 2006; 62:927-931.
    • (2006) Eur. J. Clin. Pharmacol. , vol.62 , pp. 927-931
    • Wang, G.1    Zhang, H.2    He, F.3
  • 25
    • 0141626841 scopus 로고    scopus 로고
    • Impact of CYP2D6 genotype on postoperative tramadol analgesia
    • Stamer UM, Lehnen K, Hothker F, et al. Impact of CYP2D6 genotype on postoperative tramadol analgesia. Pain 2003; 105:231-238.
    • (2003) Pain , vol.105 , pp. 231-238
    • Stamer, U.M.1    Lehnen, K.2    Hothker, F.3
  • 26
    • 0026649268 scopus 로고
    • The metabolism of tramadol by human liver microsomes
    • Paar WD, Frankus P, Dengler HJ. The metabolism of tramadol by human liver microsomes. Clin Investig 1992; 70:708-710.
    • (1992) Clin. Investig , vol.70 , pp. 708-710
    • Paar, W.D.1    Frankus, P.2    Dengler, H.J.3
  • 27
    • 0344081910 scopus 로고    scopus 로고
    • A rapid and simple CYP2D6 genotyping assay: Case study with the analgetic tramadol
    • Borlak J, Hermann R, Erb K, et al. A rapid and simple CYP2D6 genotyping assay: Case study with the analgetic tramadol. Metabolism 2003; 52:1439-1443.
    • (2003) Metabolism , vol.52 , pp. 1439-1443
    • Borlak, J.1    Hermann, R.2    Erb, K.3
  • 29
    • 0033901486 scopus 로고    scopus 로고
    • Affinity, potency and efficacy of tramadol and its metabolites at the cloned human mu-opioid receptor
    • Gillen C, Haurand M, Kobelt DJ, et al. Affinity, potency and efficacy of tramadol and its metabolites at the cloned human mu-opioid receptor. Naunyn Schmiedeberg Arch Pharmacol 2000; 362:116-121.
    • (2000) Naunyn Schmiedeberg Arch. Pharmacol. , vol.362 , pp. 116-121
    • Gillen, C.1    Haurand, M.2    Kobelt, D.J.3
  • 30
    • 78149470864 scopus 로고    scopus 로고
    • Polymorphisms of human cytochrome P450 2C9 and the functional relevance
    • Zhou SF, Zhou ZW, Huang M. Polymorphisms of human cytochrome P450 2C9 and the functional relevance. Toxicology 2010; 278:165-188.
    • (2010) Toxicology , vol.278 , pp. 165-188
    • Zhou, S.F.1    Zhou, Z.W.2    Huang, M.3
  • 31
    • 0030857031 scopus 로고    scopus 로고
    • Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C
    • Hamman MA, Thompson GA, Hall SD. Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C. Biochem Pharmacol 1997; 54:33-41.
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 33-41
    • Hamman, M.A.1    Thompson, G.A.2    Hall, S.D.3
  • 32
    • 0036336114 scopus 로고    scopus 로고
    • Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2
    • Kirchheiner J, Meineke I, Freytag G, et al. Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. Clin Pharmacol Ther 2002; 72:62-75.
    • (2002) Clin. Pharmacol. Ther. , vol.72 , pp. 62-75
    • Kirchheiner, J.1    Meineke, I.2    Freytag, G.3
  • 33
    • 0036431725 scopus 로고    scopus 로고
    • Oxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenase
    • Sandberg M, Yasar U, Stromberg P, et al. Oxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenase. Br J Clin Pharmacol 2002; 54:423-429.
    • (2002) Br. J. Clin. Pharmacol. , vol.54 , pp. 423-429
    • Sandberg, M.1    Yasar, U.2    Stromberg, P.3
  • 34
    • 33644521200 scopus 로고    scopus 로고
    • Accumulation of celecoxib with a 7-fold higher drug exposure in individuals homozygous for CYP2C9-3
    • Lundblad MS, Ohlsson S, Johansson P, et al. Accumulation of celecoxib with a 7-fold higher drug exposure in individuals homozygous for CYP2C9-3. Clin Pharmacol Ther 2006; 79:287-288.
    • (2006) Clin. Pharmacol. Ther. , vol.79 , pp. 287-288
    • Lundblad, M.S.1    Ohlsson, S.2    Johansson, P.3
  • 35
    • 36348943475 scopus 로고    scopus 로고
    • Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
    • Brandt JT, Close SL, Iturria SJ, et al. Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel. J Thromb Haemost 2007; 5:2429-2436.
    • (2007) J. Thromb. Haemost. , vol.5 , pp. 2429-2436
    • Brandt, J.T.1    Close, S.L.2    Iturria, S.J.3
  • 36
    • 79960613122 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy
    • Scott SA, Sangkuhl K, Gardner EE, et al. Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy. Clin Pharmacol Ther 2011; 90:328-332.
    • (2011) Clin. Pharmacol. Ther. , vol.90 , pp. 328-332
    • Scott, S.A.1    Sangkuhl, K.2    Gardner, E.E.3
  • 37
    • 84864335733 scopus 로고    scopus 로고
    • Identification of CYP2C19-4B: Pharmacogenetic implications for drug metabolism including clopidogrel responsiveness
    • Epub ahead of print]
    • Scott SA, Martis S, Peter I, et al. Identification of CYP2C19-4B: Pharmacogenetic implications for drug metabolism including clopidogrel responsiveness. Pharmacogenomics J 2011. [Epub ahead of print]
    • (2011) Pharmacogenomics J.
    • Scott, S.A.1    Martis, S.2    Peter, I.3
  • 39
    • 3342919012 scopus 로고    scopus 로고
    • Anesthetic requirement is increased in redheads
    • Liem EB, Lin CM, Suleman MI, et al. Anesthetic requirement is increased in redheads. Anesthesiology 2004; 101:279-283.
    • (2004) Anesthesiology , vol.101 , pp. 279-283
    • Liem, E.B.1    Lin, C.M.2    Suleman, M.I.3
  • 40
    • 84863790386 scopus 로고    scopus 로고
    • The influence of GABAAg2 genetic polymorphism on the emergence agitation induced by sevoflurane
    • Park CS. The influence of GABAAg2 genetic polymorphism on the emergence agitation induced by sevoflurane. Korean J Anesthesiol 2008; 55:139-144.
    • (2008) Korean J. Anesthesiol. , vol.55 , pp. 139-144
    • Park, C.S.1
  • 41
    • 0035165506 scopus 로고    scopus 로고
    • Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes
    • Court MH, Duan SX, Hesse LM, et al. Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes. Anesthesiology 2001; 94:110-119.
    • (2001) Anesthesiology , vol.94 , pp. 110-119
    • Court, M.H.1    Duan, S.X.2    Hesse, L.M.3
  • 42
    • 72949119743 scopus 로고    scopus 로고
    • Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6
    • Mo SL, Liu YH, Duan W, et al. Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6. Curr Drug Metab 2009; 10:730-753.
    • (2009) Curr. Drug Metab. , vol.10 , pp. 730-753
    • Mo, S.L.1    Liu, Y.H.2    Duan, W.3
  • 43
    • 0028091043 scopus 로고
    • Pharmacology of benzodiazepine receptors: An update
    • Sieghart W. Pharmacology of benzodiazepine receptors: An update. J Psychiatry Neurosci 1994; 19:24-29.
    • (1994) J. Psychiatry Neurosci. , vol.19 , pp. 24-29
    • Sieghart, W.1
  • 44
    • 28844431530 scopus 로고    scopus 로고
    • CYP2C19 genotype affects diazepam pharmacokinetics and emergence from general anesthesia
    • Inomata S, Nagashima A, Itagaki F, et al. CYP2C19 genotype affects diazepam pharmacokinetics and emergence from general anesthesia. Clin Pharmacol Ther 2005; 78:647-655.
    • (2005) Clin. Pharmacol. Ther. , vol.78 , pp. 647-655
    • Inomata, S.1    Nagashima, A.2    Itagaki, F.3
  • 45
    • 0033375477 scopus 로고    scopus 로고
    • Effect of the gene dosage of CgammaP2C19 on diazepam metabolism in Chinese subjects
    • Qin XP, Xie HG, Wang W, et al. Effect of the gene dosage of CgammaP2C19 on diazepam metabolism in Chinese subjects. Clin Pharmacol Ther 1999; 66: 642-646.
    • (1999) Clin. Pharmacol. Ther. , vol.66 , pp. 642-646
    • Qin, X.P.1    Xie, H.G.2    Wang, W.3
  • 46
    • 0142250945 scopus 로고    scopus 로고
    • Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women
    • Floyd MD, Gervasini G, Masica AL, et al. Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women. Pharmacogenetics 2003; 13:595-606.
    • (2003) Pharmacogenetics , vol.13 , pp. 595-606
    • Floyd, M.D.1    Gervasini, G.2    Masica, A.L.3
  • 47
    • 14644400494 scopus 로고    scopus 로고
    • The impact of pharmacogenomics on postoperative nausea and vomiting: Do CYP2D6 allele copy number and polymorphisms affect the success or failure of ondansetron prophylaxis
    • Candiotti KA, Birnbach DJ, Lubarsky DA, et al. The impact of pharmacogenomics on postoperative nausea and vomiting: Do CYP2D6 allele copy number and polymorphisms affect the success or failure of ondansetron prophylaxis? Anesthesiology 2005; 102:543-549.
    • (2005) Anesthesiology , vol.102 , pp. 543-549
    • Candiotti, K.A.1    Birnbach, D.J.2    Lubarsky, D.A.3
  • 48
    • 14644436410 scopus 로고    scopus 로고
    • Increased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheads
    • Liem EB, Joiner TV, Tsueda K, et al. Increased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheads. Anesthesiology 2005; 102:509-514.
    • (2005) Anesthesiology , vol.102 , pp. 509-514
    • Liem, E.B.1    Joiner, T.V.2    Tsueda, K.3
  • 49
    • 79955463893 scopus 로고    scopus 로고
    • Pharmacogenetics: From bench to byte - An update of guidelines
    • Swen JJ, Nijenhuis M, De Boer A, et al. Pharmacogenetics: From bench to byte - An update of guidelines. Clin Pharmacol Ther 2011; 89:662-673.
    • (2011) Clin. Pharmacol. Ther. , vol.89 , pp. 662-673
    • Swen, J.J.1    Nijenhuis, M.2    De Boer, A.3
  • 50
    • 59649106561 scopus 로고    scopus 로고
    • Effects of polymorphism of the beta 1) adrenoreceptor and CYP2D6 on the therapeutic effects of metoprolol
    • Yuan H, Huang Z, Yang G, et al. Effects of polymorphism of the beta(1) adrenoreceptor and CYP2D6 on the therapeutic effects of metoprolol. J Int Med Res 2008; 36:1354-1362.
    • (2008) J. Int. Med. Res. , Issue.36 , pp. 1354-1362
    • Yuan, H.1    Huang, Z.2    Yang, G.3
  • 51
    • 0037385575 scopus 로고    scopus 로고
    • A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade
    • Sofowora GG, Dishy V, Muszkat M, et al. A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade. Clin Pharmacol Ther 2003; 73:366-371.
    • (2003) Clin. Pharmacol. Ther. , vol.73 , pp. 366-371
    • Sofowora, G.G.1    Dishy, V.2    Muszkat, M.3
  • 52
    • 39049126454 scopus 로고    scopus 로고
    • Role of pharmacogenetics in variable response to drugs: Focus on opioids
    • Kadiev E, Patel V, Rad P, et al. Role of pharmacogenetics in variable response to drugs: Focus on opioids. Expert Opin Drug Metab Toxicol 2008; 4:77-91.
    • (2008) Expert Opin. Drug Metab. Toxicol. , vol.4 , pp. 77-91
    • Kadiev, E.1    Patel, V.2    Rad, P.3
  • 53
    • 74049164509 scopus 로고    scopus 로고
    • Clinical implications of opioid pharmacogenetics
    • Argoff CE. Clinical implications of opioid pharmacogenetics. Clin J pain 2010; 26 (Suppl 10):S16-S20.
    • (2010) Clin. J. pain , vol.26 , Issue.SUPPL.10
    • Argoff, C.E.1
  • 54
    • 80053914289 scopus 로고    scopus 로고
    • The metabolism of opioid agents and the clinical impact of their active metabolites
    • Smith HS. The metabolism of opioid agents and the clinical impact of their active metabolites. Clin J Pain 2011; 27:824-838.
    • (2011) Clin. J. Pain , vol.27 , pp. 824-838
    • Smith, H.S.1
  • 56
    • 34547644659 scopus 로고    scopus 로고
    • Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication
    • Kirchheiner J, Schmidt H, Tzvetkov M, et al. Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication. Pharmacogenomics J 2007; 7:257-265.
    • (2007) Pharmacogenomics J. , vol.7 , pp. 257-265
    • Kirchheiner, J.1    Schmidt, H.2    Tzvetkov, M.3
  • 57
    • 33846465345 scopus 로고    scopus 로고
    • Safety of codeine during breastfeeding: Fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine
    • Madadi P, Koren G, Cairns J, et al. Safety of codeine during breastfeeding: Fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine. Can Fam Physician 2007; 53:33-35.
    • (2007) Can. Fam. Physician , vol.53 , pp. 33-35
    • Madadi, P.1    Koren, G.2    Cairns, J.3
  • 58
    • 57749180179 scopus 로고    scopus 로고
    • Pharmacogenetics of neonatal opioid toxicity following maternal use of codeine during breastfeeding: A case-control study
    • Madadi P, Ross C, Hayden M, et al. Pharmacogenetics of neonatal opioid toxicity following maternal use of codeine during breastfeeding: A case-control study. Clin Pharmacol Ther 2009; 85:31-35.
    • (2009) Clin. Pharmacol. Ther. , vol.85 , pp. 31-35
    • Madadi, P.1    Ross, C.2    Hayden, M.3
  • 59
    • 32944461710 scopus 로고    scopus 로고
    • Interethnic differences in genetic polymorphisms of CYP2D6 in the US population: Clinical implications
    • Bernard S, Neville KA, Nguyen AT, et al. Interethnic differences in genetic polymorphisms of CYP2D6 in the US population: Clinical implications. Oncologist 2006; 11:126-135.
    • (2006) Oncologist , vol.11 , pp. 126-135
    • Bernard, S.1    Neville, K.A.2    Nguyen, A.T.3
  • 61
    • 84863806884 scopus 로고    scopus 로고
    • FDA
    • Accessed 11 May 2012]
    • FDA. Pharmacogenomic Biomarkers in Drug Labels. 2012. http://www. fda.gov/Drugs/ScienceResearch/ResearchAreas/Pharmacogenetics/ucm 083378.htm. [Accessed 11 May 2012].
    • (2012) Pharmacogenomic Biomarkers in Drug Labels
  • 62
    • 48949119082 scopus 로고    scopus 로고
    • Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia
    • Nagele P, Zeugswetter B, Wiener C, et al. Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia. Anesthesiology 2008; 109:36-43.
    • (2008) Anesthesiology , vol.109 , pp. 36-43
    • Nagele, P.1    Zeugswetter, B.2    Wiener, C.3
  • 63
    • 70349572483 scopus 로고    scopus 로고
    • The association of malignant hyperthermia and unusual disease: When you're hot you're hot or maybe not
    • Davis PJ, Brandom BW. The association of malignant hyperthermia and unusual disease: When you're hot you're hot or maybe not. Anesth Analg 2009; 109:1001-1003.
    • (2009) Anesth. Analg. , vol.109 , pp. 1001-1003
    • Davis, P.J.1    Brandom, B.W.2
  • 64
    • 33750127160 scopus 로고    scopus 로고
    • Frequency and localization of mutations in the 106 exons of the RYR1 gene in 50 individuals with malignant hyperthermia
    • Galli L, Orrico A, Lorenzini S, et al. Frequency and localization of mutations in the 106 exons of the RYR1 gene in 50 individuals with malignant hyperthermia. Hum Mutat 2006; 27:830.
    • (2006) Hum. Mutat. , vol.27 , pp. 830
    • Galli, L.1    Orrico, A.2    Lorenzini, S.3
  • 65
    • 34548105118 scopus 로고    scopus 로고
    • Polymorphic CYP2B6: Molecular mechanisms and emerging clinical significance
    • Zanger UM, Klein K, Saussele T, et al. Polymorphic CYP2B6: Molecular mechanisms and emerging clinical significance. Pharmacogenomics 2007; 8:743-759.
    • (2007) Pharmacogenomics , vol.8 , pp. 743-759
    • Zanger, U.M.1    Klein, K.2    Saussele, T.3
  • 66
    • 35148901576 scopus 로고    scopus 로고
    • An investigation of potential genetic determinants of propofol requirements and recovery from anaesthesia
    • Iohom G, Ni Chonghaile M, O'Brien JK, et al. An investigation of potential genetic determinants of propofol requirements and recovery from anaesthesia. Eur J Anaesthesiol 2007; 24:912-919.
    • (2007) Eur. J. Anaesthesiol. , vol.24 , pp. 912-919
    • Iohom, G.1    Ni Chonghaile, M.2    O'Brien, J.K.3
  • 67
    • 0035039705 scopus 로고    scopus 로고
    • Involvement of human liver cytochrome P4502B6 in the metabolism of propofol
    • Oda Y, Hamaoka N, Hiroi T, et al. Involvement of human liver cytochrome P4502B6 in the metabolism of propofol. Br J Clin Pharmacol 2001; 51:281-285.
    • (2001) Br. J. Clin. Pharmacol. , vol.51 , pp. 281-285
    • Oda, Y.1    Hamaoka, N.2    Hiroi, T.3
  • 68
    • 33646496331 scopus 로고    scopus 로고
    • Herbal monoterpene alcohols inhibit propofol metabolism and prolong anesthesia time
    • Li Lin A, Shangari N, Chan TS, et al. Herbal monoterpene alcohols inhibit propofol metabolism and prolong anesthesia time. Life Sci 2006; 79:21-29.
    • (2006) Life Sci. , vol.79 , pp. 21-29
    • Li Lin, A.1    Shangari, N.2    Chan, T.S.3
  • 69
    • 70350710314 scopus 로고    scopus 로고
    • Do variations in the 5-HT3A and 5-HT3B serotonin receptor genes (HTR3A and HTR3B) influence the occurrence of postoperative vomiting
    • Rueffert H, Thieme V, Wallenborn J, et al. Do variations in the 5-HT3A and 5-HT3B serotonin receptor genes (HTR3A and HTR3B) influence the occurrence of postoperative vomiting? Anesth Analg 2009; 109:1442-1447.
    • (2009) Anesth. Analg. , vol.109 , pp. 1442-1447
    • Rueffert, H.1    Thieme, V.2    Wallenborn, J.3
  • 70
    • 79959923977 scopus 로고    scopus 로고
    • The dopamine receptor 2 (DRD2) gene is associated with opioid-induced nausea and emesis
    • Ribeiro-Dasilva M, Wallace M, Glover T. The dopamine receptor 2 (DRD2) gene is associated with opioid-induced nausea and emesis. J Pain 2009; 10 (Suppl 1):S29.
    • (2009) J. Pain , vol.10 , Issue.SUPPL.1
    • Ribeiro-Dasilva, M.1    Wallace, M.2    Glover, T.3
  • 71
    • 79959492966 scopus 로고    scopus 로고
    • Genome-wide association study using pooled DNA to identify candidate markers mediating susceptibility to postoperative nausea and vomiting
    • Janicki PK, Vealey R, Liu J, et al. Genome-wide association study using pooled DNA to identify candidate markers mediating susceptibility to postoperative nausea and vomiting. Anesthesiology 2011; 115:54-64.
    • (2011) Anesthesiology , vol.115 , pp. 54-64
    • Janicki, P.K.1    Vealey, R.2    Liu, J.3
  • 72
    • 0028972886 scopus 로고
    • Cloning and characterization of the human GABAA receptor alpha 4 subunit: Identification of a unique diazepaminsensitive binding site
    • Yang W, Drewe JA, Lan NC. Cloning and characterization of the human GABAA receptor alpha 4 subunit: Identification of a unique diazepaminsensitive binding site. Eur J Pharmacol 1995; 291:319-325.
    • (1995) Eur. J. Pharmacol. , vol.291 , pp. 319-325
    • Yang, W.1    Drewe, J.A.2    Lan, N.C.3
  • 73
    • 0032588197 scopus 로고    scopus 로고
    • Relationship between a GABAA alpha 6 Pro385Ser substitution and benzodiazepine sensitivity
    • Iwata N, Cowley DS, Radel M, et al. Relationship between a GABAA alpha 6 Pro385Ser substitution and benzodiazepine sensitivity. Am J Psychiatry 1999; 156:1447-1449.
    • (1999) Am. J. Psychiatry , vol.156 , pp. 1447-1449
    • Iwata, N.1    Cowley, D.S.2    Radel, M.3
  • 74
    • 34249980057 scopus 로고    scopus 로고
    • A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity
    • Sheets PL, Jackson JO 2nd, Waxman SG, et al. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity. J Physiol 2007; 581:1019-1031.
    • (2007) J. Physiol. , vol.581 , pp. 1019-1031
    • Sheets, P.L.1    Jackson II, J.O.2    Waxman, S.G.3
  • 75
    • 25144508158 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor genotype and survival among patients receiving beta-blocker therapy after an acute coronary syndrome
    • Lanfear DE, Jones PG, Marsh S, et al. Beta2-adrenergic receptor genotype and survival among patients receiving beta-blocker therapy after an acute coronary syndrome. JAMA 2005; 294:1526-1533.
    • (2005) JAMA , vol.294 , pp. 1526-1533
    • Lanfear, D.E.1    Jones, P.G.2    Marsh, S.3
  • 76
    • 33846943340 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor genotype predicts survival: Implications and future directions
    • Lanfear DE, Spertus JA, Mcleod HL. Beta2-adrenergic receptor genotype predicts survival: Implications and future directions. J Cardiovasc Nurs 2006; 21:474-477.
    • (2006) J. Cardiovasc Nurs , vol.21 , pp. 474-477
    • Lanfear, D.E.1    Spertus, J.A.2    Mcleod, H.L.3
  • 77
    • 77952007675 scopus 로고    scopus 로고
    • Observational study of the effect of muopioid receptor genetic polymorphism on intrathecal opioid labor analgesia and postcesarean delivery analgesia
    • Wong CA, Mccarthy RJ, Blouin J, et al. Observational study of the effect of muopioid receptor genetic polymorphism on intrathecal opioid labor analgesia and postcesarean delivery analgesia. Int J Obstetr Anesth 2010; 19:246-253.
    • (2010) Int. J. Obstetr. Anesth. , vol.19 , pp. 246-253
    • Wong, C.A.1    Mccarthy, R.J.2    Blouin, J.3
  • 78
    • 28844493673 scopus 로고    scopus 로고
    • Arg16 homozygosity of the beta2-adrenergic receptor improves the outcome after beta2-agonist tocolysis for preterm labor
    • Landau R, Morales MA, Antonarakis SE, et al. Arg16 homozygosity of the beta2-adrenergic receptor improves the outcome after beta2-agonist tocolysis for preterm labor. Clin Pharmacol Ther 2005; 78:656-663.
    • (2005) Clin. Pharmacol. Ther. , vol.78 , pp. 656-663
    • Landau, R.1    Morales, M.A.2    Antonarakis, S.E.3
  • 79
    • 0036832451 scopus 로고    scopus 로고
    • Beta2-Adrenergic receptor genotype and preterm delivery
    • Landau R, Xie HG, Dishy V, et al. beta2-Adrenergic receptor genotype and preterm delivery. Am J Obstet Gynecol 2002; 187:1294-1298.
    • (2002) Am. J. Obstet. Gynecol. , vol.187 , pp. 1294-1298
    • Landau, R.1    Xie, H.G.2    Dishy, V.3
  • 80
    • 4644319643 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor gene polymorphisms and pregnancy outcome
    • Doh K, Sziller I, Vardhana S, et al. Beta2-adrenergic receptor gene polymorphisms and pregnancy outcome. J Perinat Med 2004; 32:413-417.
    • (2004) J. Perinat Med. , vol.32 , pp. 413-417
    • Doh, K.1    Sziller, I.2    Vardhana, S.3
  • 81
    • 31044441473 scopus 로고    scopus 로고
    • Pharmacogenetics and the concept of individualized medicine
    • Shastry BS. Pharmacogenetics and the concept of individualized medicine. Pharmacogenomics J 2006; 6:16-21.
    • (2006) Pharmacogenomics J. , vol.6 , pp. 16-21
    • Shastry, B.S.1
  • 82
    • 84860573467 scopus 로고    scopus 로고
    • Unequal burden of perioperative pain and opioid related adverse effects in African-American and Caucasian children
    • Sadhasivam S. Unequal burden of perioperative pain and opioid related adverse effects in African-American and Caucasian children. Pediatrics 2012; 129:832-838.
    • (2012) Pediatrics , Issue.129 , pp. 832-838
    • Sadhasivam, S.1
  • 83
    • 84860510571 scopus 로고    scopus 로고
    • Morphine clearance in children: Does race or genetics matter
    • in press
    • Sadhasivam S, Krekels E, Chidambaran V, et al. Morphine clearance in children: Does race or genetics matter? Opioid Manag (in press).
    • Opioid Manag
    • Sadhasivam, S.1    Krekels, E.2    Chidambaran, V.3
  • 84
    • 85043400646 scopus 로고    scopus 로고
    • PGRN [Accessed 5 May 2011
    • PGRN. PGRN vision and mission statement. 2012. http://www.nigms.nih. gov/Research/FeaturedPrograms/PGRN/Background/Mission2010.htm. [Accessed 5 May 2011].
    • (2012) PGRN Vision and Mission Statement
  • 85
    • 79956141274 scopus 로고    scopus 로고
    • Pain management in the 21st century: Utilization of pharmacogenomics and therapeutic drug monitoring
    • Jannetto PJ, Bratanow NC. Pain management in the 21st century: Utilization of pharmacogenomics and therapeutic drug monitoring. Expert Opin Drug Metab Toxicol 2011; 7:745-752.
    • (2011) Expert Opin. Drug Metab. Toxicol. , vol.7 , pp. 745-752
    • Jannetto, P.J.1    Bratanow, N.C.2
  • 86
    • 79951809825 scopus 로고    scopus 로고
    • CPIC: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network
    • Relling MV, Klein TE. CPIC: CLINICAL Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin Pharmacol Ther 2011; 89:464-467.
    • (2011) Clin. Pharmacol. Ther. , vol.89 , pp. 464-467
    • Relling, M.V.1    Klein, T.E.2


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