Genome-wide association study using pooled DNA to identify candidate markers mediating susceptibility to postoperative nausea and vomiting

Anesthesiology

Volumn 115, Issue 1, 2011, Pages 54-64

  Janicki, Piotr K ^a,b   Vealey, Ryan ^c   Liu, Jiabin ^d   Escajeda, Jeremiah ^b   Postula, Marek ^e   Welker, Kelli ^b  

^a Department of Anesthesiology   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^d HOSPITAL FOR SPECIAL SURGERY   (United States)

^e MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; DNA; INHALATION ANESTHETIC AGENT; MUSCARINIC ACETYLCHOLINE RECEPTOR 3; MUSCARINIC M3 RECEPTOR; UNCLASSIFIED DRUG;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; DNA DETERMINATION; FEMALE; GENE FREQUENCY; GENE LOCUS; GENE POOL; GENE TARGETING; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOME; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MARKER GENE; MICROARRAY ANALYSIS; MOLECULAR PROBE; POSTOPERATIVE NAUSEA AND VOMITING; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; AGED; COHORT STUDIES; DATA INTERPRETATION, STATISTICAL; DNA; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC MARKERS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MICROARRAY ANALYSIS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; POSTOPERATIVE NAUSEA AND VOMITING; YOUNG ADULT;

EID: 79959492966     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e31821810c7     Document Type: Article

References (38)

1. Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N: A simplified risk score for predicting postoperative nausea and vomiting: Conclusions from cross-validations between two centers. ANESTHESIOLOGY 1999; 91:693-700 (Pubitemid 29418651)
2. Eberhart LH, Geldner G, Kranke P, Morin AM, Schäuffelen A, Treiber H, Wulf H: The development and validation of a risk score to predict the probability of postoperative vomiting in pediatric patients. Anesth Analg 2004; 99:1630-7 (Pubitemid 39551894)
3. Gan TJ: Risk factors for postoperative nausea and vomiting. Anesth Analg 2006; 102:1884-98 (Pubitemid 43799873)
4. Candiotti KA, Birnbach DJ, Lubarsky DA, Nhuch F, Kamat A, Koch WH, Nikoloff M, Wu L, Andrews D: The impact of pharmacogenomics on postoperative nausea and vomiting: Do CYP2D6 allele copy number and polymorphisms affect the success or failure of ondansetron prophylaxis? ANESTHESIOLOGY 2005; 102:543-9 (Pubitemid 40315143)
5. Janicki PK: Cytochrome P450 2D6 metabolism and 5-hydroxytryptamine type 3 receptor antagonists for postoperative nausea and vomiting. Med Sci Monit 2005; 11: RA322-8 (Pubitemid 41482745)
6. Janicki PK, Schuler HG, Jarzembowski TM, Rossi M 2nd: Prevention of postoperative nausea and vomiting with granisetron and dolasetron in relation to CYP2D6 genotype. Anesth Analg 2006; 102:1127-33
7. Nielsen M, Olsen NV: Genetic polymorphisms in the cytochrome P450 system and efficacy of 5-hydroxytryptamine type 3 receptor antagonists for postoperative nausea and vomiting. Br J Anaesth 2008; 101:441-5
8. Kaiser R, Sezer O, Papies A, Bauer S, Schelenz C, Tremblay PB, Possinger K, Roots I, Brockmöller J: Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes. J Clin Oncol 2002; 20:2805-11 (Pubitemid 34651509)
9. Kaiser R, Tremblay PB, Sezer O, Possinger K, Roots I, Brockmöller J: Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists. Pharmacogenetics 2004; 14:271-8 (Pubitemid 38638913)
10. Rueffert H, Thieme V, Wallenborn J, Lemnitz N, Bergmann A, Rudlof K, Wehner M, Olthoff D, Kaisers UX: Do variations in the 5-HT3A and 5-HT3B serotonin receptor genes (HTR3A and HTR3B) influence the occurrence of postoperative vomiting? Anesth Analg 2009; 109:1442-7
11. Tremblay PB, Kaiser R, Sezer O, Rosler N, Schelenz C, Possinger K, Roots I, Brockmoller J: Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients. J Clin Oncol 2003; 21:2147-55 (Pubitemid 46606363)
12. Nakagawa M, Kuri M, Kambara N, Tanigami H, Tanaka H, Kishi Y, Hamajima N: Dopamine D2 receptor Taq IA polymorphism is associated with postoperative nausea and vomiting. J Anesth 2008; 22:397-403
13. Abraham R, Moskvina V, Sims R, Hollingworth P, Morgan A, Georgieva L, Dowzell K, Cichon S, Hillmer AM, O'Donovan MC, Williams J, Owen MJ, Kirov G: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Med Genomics 2008; 1:44
14. Brown KM, Macgregor S, Montgomery GW, Craig DW, Zhao ZZ, Iyadurai K, Henders AK, Homer N, Campbell MJ, Stark M, Thomas S, Schmid H, Holland EA, Gillanders EM, Duffy DL, Maskiell JA, Jetann J, Ferguson M, Stephan DA, Cust AE, Whiteman D, Green A, Olsson H, Puig S, Ghiorzo P, Hansson J, Demenais F, Goldstein AM, Gruis NA, Elder DE, Bishop JN, Kefford RF, Giles GG, Armstrong BK, Aitken JF, Hopper JL, Martin NG, Trent JM, Mann GJ, Hayward NK: Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat Genet 2008; 40:838-40 (Pubitemid 351913651)
15. Craig DW, Huentelman MJ, Hu-Lince D, Zismann VL, Kruer MC, Lee AM, Puffenberger EG, Pearson JM, Stephan DA: Identification of disease causing loci using an array-based genotyping approach on pooled DNA. BMC Genomics 2005; 6:138
16. Craig DW, Millis MP, DiStefano JK: Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to type 1 diabetes. Diabet Med 2009; 26:1090-8
17. Hanson RL, Craig DW, Millis MP, Yeatts KA, Kobes S, Pearson JV, Lee AM, Knowler WC, Nelson RG, Wolford JK: Identification of PVT1 as a candidate gene for end-stage renal disease in type 2 diabetes using a pooling-based genome-wide single nucleotide polymorphism association study. Diabetes 2007; 56:975-83 (Pubitemid 46525073)
18. Kirov G, Zaharieva I, Georgieva L, Moskvina V, Nikolov I, Cichon S, Hillmer A, Toncheva D, Owen MJ, O'Donovan MC: A genome-wide association study in 574 schizophrenia trios using DNA pooling. Mol Psychiatry 2009; 14:796-803
19. Macgregor S, Visscher PM, Montgomery G: Analysis of pooled DNA samples on high density arrays without prior knowledge of differential hybridization rates. Nucleic Acids Res 2006; 34:e55
20. Macgregor S, Zhao ZZ, Henders A, Nicholas MG, Montgomery GW, Visscher PM: Highly cost-efficient genome-wide association studies using DNA pools and dense SNP arrays. Nucleic Acids Res 2008; 36:e35
21. Moskvina V, Norton N, Williams N, Holmans P, Owen M, O'donovan M: Streamlined analysis of pooled genotype data in SNP-based association studies. Genet Epidemiol 2005; 28:273-82 (Pubitemid 40404581)
22. Pearson JV, Huentelman MJ, Halperin RF, Tembe WD, Melquist S, Homer N, Brun M, Szelinger S, Coon KD, Zismann VL, Webster JA, Beach T, Sando SB, Aasly JO, Heun R, Jessen F, Kolsch H, Tsolaki M, Daniilidou M, Reiman EM, Papassotiropoulos A, Hutton ML, Stephan DA, Craig DW: Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies. Am J Hum Genet 2007; 80:126-39 (Pubitemid 46047656)
23. Sebastiani P, Abad-Grau MM: Bayesian estimates of linkage disequilibrium. BMC Genet 2007; 8:36
24. Galvan A, Falvella FS, Spinola M, Frullanti E, Leoni VP, Noci S, Alonso MR, Zolin A, Spada E, Milani S, Pastorino U, Incarbone M, Santambrogio L, Neira AG, Dragani TA: A polygenic model with common variants may predict lung adenocarcinoma risk in humans. Int J Cancer 2008; 123:2327-30
25. Steer S, Abkevich V, Gutin A, Cordell HJ, Gendall KL, Merriman ME, Rodger RA, Rowley KA, Chapman P, Gow P, Harrison AA, Highton J, Jones PB, O'Donnell J, Stamp L, Fitzgerald L, Iliev D, Kouzmine A, Tran T, Skolnick MH, Timms KM, Lanchbury JS, Merriman TR: Genomic DNA pooling for whole-genome association scans in complex disease: Empirical demonstration of efficacy in rheumatoid arthritis. Genes Immun 2007; 8:57-68 (Pubitemid 46158104)
26. Sebastiani P, Zhao Z, Abad-Grau MM, Riva A, Hartley SW, Sedgewick AE, Doria A, Montano M, Melista E, Terry D, Perls TT, Steinberg MH, Baldwin CT: A hierarchical and modular approach to the discovery of robust associations in genomewide association studies from pooled DNA samples. BMC Genet 2008; 9:6
27. Skol AD, Scott LJ, Abecasis GR, Boehnke M: Joint analysis is more efficient than replication-based analysis for two-stage genomewide association studies. Nat Genet 2006; 38:209-13 (Pubitemid 43177235)
28. Drgon T, Zhang PW, Johnson C, Walther D, Hess J, Nino M, Uhl GR: Genome wide association for addiction: Replicated results and comparisons of two analytic approaches. PLoS One 2010; 5:e8832
29. Dupont WD, Plummer WD Jr: Power and sample size calculations. A review and computer program. Control Clin Trials 1990; 11:116-28 (Pubitemid 20136185)
30. Janicki P, Liu J: Accuracy of allele frequency estimates in pool DNA analyzed by high-density Illumina Human 610-Quad microarray. The Internet Journal of Genomics and Proteomics 2009; 5:1-12
31. Balding DJ: A tutorial on statistical methods for population association studies. Nat Rev Genet 2006; 7:781-91 (Pubitemid 44413222)
32. Forsythe SM, Kogut PC, McConville JF, Fu Y, McCauley JA, Halayko AJ, Liu HW, Kao A, Fernandes DJ, Bellam S, Fuchs E, Sinha S, Bell GI, Camoretti-Mercado B, Solway J: Structure and transcription of the human m3 muscarinic receptor gene. Am J Respir Cell Mol Biol 2002; 26:298-305 (Pubitemid 34170056)
33. Schwarz RD, Callahan MJ, Coughenour LL, Dickerson MR, Kinsora JJ, Lipinski WJ, Raby CA, Spencer CJ, Tecle H: Milameline (CI-979/RU35926): A muscarinic receptor agonist with cognition-activating properties: Biochemical and in vivo characterization. J Pharmacol Exp Ther 1999; 291: 812-22 (Pubitemid 29503557)
34. Golding JF, Stott JR: Comparison of the effects of a selective muscarinic receptor antagonist and hyoscine (scopolamine) on motion sickness, skin conductance and heart rate. Br J Clin Pharmacol 1997; 43:633-7 (Pubitemid 27283573)
35. Pedigo NW Jr, Brizzee KR: Muscarinic cholinergic receptors in area postrema and brainstem areas regulating emesis. Brain Res Bull 1985; 14:169-77 (Pubitemid 15124312)
36. Donfack J, Kogut P, Forsythe S, Solway J, Ober C: Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy. J Allergy Clin Immunol 2003; 111:527-32 (Pubitemid 36337873)
37. Guo Y, Traurig M, Ma L, Kobes S, Harper I, Infante AM, Bogardus C, Baier LJ, Prochazka M: CHRM3 gene variation is associated with decreased acute insulin secretion and increased risk for early-onset type 2 diabetes in Pima Indians. Diabetes 2006; 55:3625-9 (Pubitemid 44923626)
38. Candiotti K: Anesthesia and pharmacogenomics: Not ready for prime time. Anesth Analg 2009; 109:1377-8