메뉴 건너뛰기




Volumn 18, Issue 7, 2012, Pages 333-340

Active DNA demethylation in mammalian preimplantation embryos: New insights and new perspectives

Author keywords

5 hydroxymethylcytosine; 5 methylcytosine; Active DNA demethylation; Preimplantation embryos; Zygote

Indexed keywords

DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B;

EID: 84863740068     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gas014     Document Type: Review
Times cited : (25)

References (70)
  • 1
    • 70349706136 scopus 로고    scopus 로고
    • Demethylation dynamics of the paternal genome in pronuclear-stage bovine zygotes produced by in vitro fertilization and ooplasmic injection of freeze-thawed or freeze-dried spermatozoa
    • Abdalla H, Hirabayashi M, Hochi S. Demethylation dynamics of the paternal genome in pronuclear-stage bovine zygotes produced by in vitro fertilization and ooplasmic injection of freeze-thawed or freeze-dried spermatozoa. J Reprod Dev 2009;55: 433-439.
    • (2009) J Reprod Dev , vol.55 , pp. 433-439
    • Abdalla, H.1    Hirabayashi, M.2    Hochi, S.3
  • 2
    • 21844464297 scopus 로고    scopus 로고
    • C→T mutagenesis and gammaradiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases
    • An Q, Robins P, Lindahl T, Barnes DE. C→T mutagenesis and gammaradiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases. EMBO J 2005;24: 2205-2213.
    • (2005) EMBO J , vol.24 , pp. 2205-2213
    • An, Q.1    Robins, P.2    Lindahl, T.3    Barnes, D.E.4
  • 3
    • 78951481941 scopus 로고    scopus 로고
    • Epigenetic characteristics of paternal chromatin in interspecies zygotes
    • Barnetova I, Fulka H, Fulka J Jr. Epigenetic characteristics of paternal chromatin in interspecies zygotes. J Reprod Dev 2010;56: 601-606.
    • (2010) J Reprod Dev , vol.56 , pp. 601-606
    • Barnetova, I.1    Fulka, H.2    Fulka Jr., J.3
  • 7
    • 77649104794 scopus 로고    scopus 로고
    • Reprogramming towards pluripotency requires AID-dependent DNA demethylation
    • Bhutani N, Brady JJ, Damian M, Sacco A, Corbel SY, Blau HM. Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 2009;463: 1042-1047.
    • (2009) Nature , vol.463 , pp. 1042-1047
    • Bhutani, N.1    Brady, J.J.2    Damian, M.3    Sacco, A.4    Corbel, S.Y.5    Blau, H.M.6
  • 8
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002;16: 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 12
    • 0035923602 scopus 로고    scopus 로고
    • Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos
    • Dean W, Santos F, Stojkovic M, Zakhartchenko V, Walter J, Wolf E, Reik W. Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos. Proc Natl Acad Sci USA 2001;98: 13734-13738.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13734-13738
    • Dean, W.1    Santos, F.2    Stojkovic, M.3    Zakhartchenko, V.4    Walter, J.5    Wolf, E.6    Reik, W.7
  • 16
    • 77957659555 scopus 로고    scopus 로고
    • Cytidine deaminases: AIDing DNA demethylation?
    • Fritz EL, Papavasiliou FN. Cytidine deaminases: AIDing DNA demethylation? Genes Dev 2010;24: 2107-2114.
    • (2010) Genes Dev , vol.24 , pp. 2107-2114
    • Fritz, E.L.1    Papavasiliou, F.N.2
  • 17
    • 33750147831 scopus 로고    scopus 로고
    • No differences in the DNA methylation pattern in mouse zygotes produced in vivo, in vitro, or by intracytoplasmic sperm injection
    • Fulka H, Fulka J Jr. No differences in the DNA methylation pattern in mouse zygotes produced in vivo, in vitro, or by intracytoplasmic sperm injection. Fertil Steril 2006;86: 1534-1536.
    • (2006) Fertil Steril , vol.86 , pp. 1534-1536
    • Fulka, H.1    Fulka Jr., J.2
  • 18
    • 11144285884 scopus 로고    scopus 로고
    • DNA methylation pattern in human zygotes and developing embryos
    • Fulka H, Mrazek M, Tepla O, Fulka J Jr. DNA methylation pattern in human zygotes and developing embryos. Reproduction 2004;128: 703-708.
    • (2004) Reproduction , vol.128 , pp. 703-708
    • Fulka, H.1    Mrazek, M.2    Tepla, O.3    Fulka Jr., J.4
  • 19
    • 40749151505 scopus 로고    scopus 로고
    • Epigenetic analysis of human spermatozoa after their injection into ovulated mouse oocytes
    • Fulka H, Barnetova I, Mosko T, Fulka J. Epigenetic analysis of human spermatozoa after their injection into ovulated mouse oocytes. Hum Reprod 2008;23: 627-634.
    • (2008) Hum Reprod , vol.23 , pp. 627-634
    • Fulka, H.1    Barnetova, I.2    Mosko, T.3    Fulka, J.4
  • 21
    • 22544482038 scopus 로고    scopus 로고
    • The capability of reprogramming the male chromatin after fertilization is dependent on the quality of oocyte maturation
    • Gioia L, Barboni B, Turriani M, Capacchietti G, Pistilli MG, Berardinelli P, Mattioli M. The capability of reprogramming the male chromatin after fertilization is dependent on the quality of oocyte maturation. Reproduction 2005;130: 29-39.
    • (2005) Reproduction , vol.130 , pp. 29-39
    • Gioia, L.1    Barboni, B.2    Turriani, M.3    Capacchietti, G.4    Pistilli, M.G.5    Berardinelli, P.6    Mattioli, M.7
  • 23
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 2011;145: 423-434.
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 25
    • 77954345408 scopus 로고    scopus 로고
    • Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
    • Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science 2010;329: 78-82.
    • (2010) Science , vol.329 , pp. 78-82
    • Hajkova, P.1    Jeffries, S.J.2    Lee, C.3    Miller, N.4    Jackson, S.P.5    Surani, M.A.6
  • 26
    • 80052495940 scopus 로고    scopus 로고
    • Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
    • He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q, Ding J, Jia Y, Chen Z, Li L et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 2011;333: 1303-1307.
    • (2011) Science , vol.333 , pp. 1303-1307
    • He, Y.F.1    Li, B.Z.2    Li, Z.3    Liu, P.4    Wang, Y.5    Tang, Q.6    Ding, J.7    Jia, Y.8    Chen, Z.9    Li, L.10
  • 28
    • 64249157351 scopus 로고    scopus 로고
    • Epigenetic reprogramming and induced pluripotency
    • Hochedlinger K, Plath K. Epigenetic reprogramming and induced pluripotency. Development 2009;136: 509-523.
    • (2009) Development , vol.136 , pp. 509-523
    • Hochedlinger, K.1    Plath, K.2
  • 30
    • 80054097425 scopus 로고    scopus 로고
    • Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
    • Inoue A, Zhang Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 2011;334: 194.
    • (2011) Science , vol.334 , pp. 194
    • Inoue, A.1    Zhang, Y.2
  • 31
    • 79952763586 scopus 로고    scopus 로고
    • Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
    • Iqbal K, Jin SG, Pfeifer GP, Szabo PE. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc Natl Acad Sci USA 2011;108: 3642-3647.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3642-3647
    • Iqbal, K.1    Jin, S.G.2    Pfeifer, G.P.3    Szabo, P.E.4
  • 32
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010;466: 1129-1133.
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 33
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011;333: 1300-1303.
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5    Swenberg, J.A.6    He, C.7    Zhang, Y.8
  • 34
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003;33(Suppl): 245-254.
    • (2003) Nat Genet , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 38
    • 29144504429 scopus 로고    scopus 로고
    • Epigenetic abnormalities of the mouse paternal zygotic genome associated with microinsemination of round spermatids
    • Kishigami S, Van Thuan N, Hikichi T, Ohta H, Wakayama S, Mizutani E, Wakayama T. Epigenetic abnormalities of the mouse paternal zygotic genome associated with microinsemination of round spermatids. Dev Biol 2006;289: 195-205.
    • (2006) Dev Biol , vol.289 , pp. 195-205
    • Kishigami, S.1    Van Thuan, N.2    Hikichi, T.3    Ohta, H.4    Wakayama, S.5    Mizutani, E.6    Wakayama, T.7
  • 39
    • 0036333598 scopus 로고    scopus 로고
    • Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells
    • Lee J, Inoue K, Ono R, Ogonuki N, Kohda T, Kaneko-Ishino T, Ogura A, Ishino F. Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells. Development 2002; 129: 1807-1817.
    • (2002) Development , vol.129 , pp. 1807-1817
    • Lee, J.1    Inoue, K.2    Ono, R.3    Ogonuki, N.4    Kohda, T.5    Kaneko-Ishino, T.6    Ogura, A.7    Ishino, F.8
  • 41
    • 80053917872 scopus 로고    scopus 로고
    • Thymine DNA glycoslyase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites
    • Maiti A, Drohat AC. Thymine DNA glycoslyase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J Biol Chem 2011;286: 35334-35338.
    • (2011) J Biol Chem , vol.286 , pp. 35334-35338
    • Maiti, A.1    Drohat, A.C.2
  • 43
    • 0037509930 scopus 로고    scopus 로고
    • Mammalian 5-formyluracil-DNA glycosylase. 2. role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions
    • Masaoka A, Matsubara M, Hasegawa R, Tanaka T, Kurisu S, Terato H, Ohyama Y, Karino N, Matsuda A, Ide H. Mammalian 5-formyluracil-DNA glycosylase. 2. role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions. Biochemistry 2003;42: 5003-5012.
    • (2003) Biochemistry , vol.42 , pp. 5003-5012
    • Masaoka, A.1    Matsubara, M.2    Hasegawa, R.3    Tanaka, T.4    Kurisu, S.5    Terato, H.6    Ohyama, Y.7    Karino, N.8    Matsuda, A.9    Ide, H.10
  • 47
    • 62149128541 scopus 로고    scopus 로고
    • Functional analysis of male mouse haploid germ cells of various differentiation stages: early and late round spermatids are functionally equivalent in producing progeny
    • Ohta H, Sakaide Y, Wakayama T. Functional analysis of male mouse haploid germ cells of various differentiation stages: early and late round spermatids are functionally equivalent in producing progeny. Biol Reprod 2009;80: 511-517.
    • (2009) Biol Reprod , vol.80 , pp. 511-517
    • Ohta, H.1    Sakaide, Y.2    Wakayama, T.3
  • 48
    • 75749142980 scopus 로고    scopus 로고
    • A role for the elongator complex in zygotic paternal genome demethylation
    • Okada Y, Yamagata K, Hong K, Wakayama T, Zhang Y. A role for the elongator complex in zygotic paternal genome demethylation. Nature 2010;463: 554-558.
    • (2010) Nature , vol.463 , pp. 554-558
    • Okada, Y.1    Yamagata, K.2    Hong, K.3    Wakayama, T.4    Zhang, Y.5
  • 50
    • 34548818792 scopus 로고    scopus 로고
    • Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes
    • Park JS, Jeong YS, Shin ST, Lee KK, Kang YK. Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes. Dev Dyn 2007;236: 2523-2533.
    • (2007) Dev Dyn , vol.236 , pp. 2523-2533
    • Park, J.S.1    Jeong, Y.S.2    Shin, S.T.3    Lee, K.K.4    Kang, Y.K.5
  • 51
    • 77957692411 scopus 로고    scopus 로고
    • Active loss of DNA methylation in two-cell stage goat embryos
    • Park JS, Lee D, Cho S, Shin ST, Kang YK. Active loss of DNA methylation in two-cell stage goat embryos. Int J Dev Biol 2010;54: 1323-1328.
    • (2010) Int J Dev Biol , vol.54 , pp. 1323-1328
    • Park, J.S.1    Lee, D.2    Cho, S.3    Shin, S.T.4    Kang, Y.K.5
  • 54
    • 42349090375 scopus 로고    scopus 로고
    • Hypomethylation of paternal DNA in the late mouse zygote is not essential for development
    • Polanski Z, Motosugi N, Tsurumi C, Hiiragi T, Hoffmann S. Hypomethylation of paternal DNA in the late mouse zygote is not essential for development. Int J Dev Biol 2008;52: 295-298.
    • (2008) Int J Dev Biol , vol.52 , pp. 295-298
    • Polanski, Z.1    Motosugi, N.2    Tsurumi, C.3    Hiiragi, T.4    Hoffmann, S.5
  • 55
    • 77249148019 scopus 로고    scopus 로고
    • Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
    • Popp C, Dean W, Feng S, Cokus SJ, Andrews S, Pellegrini M, Jacobsen SE, Reik W. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010; 463: 1101-1105.
    • (2010) Nature , vol.463 , pp. 1101-1105
    • Popp, C.1    Dean, W.2    Feng, S.3    Cokus, S.J.4    Andrews, S.5    Pellegrini, M.6    Jacobsen, S.E.7    Reik, W.8
  • 58
    • 82855176833 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells
    • Saitou M, Kagiwada S, Kurimoto K. Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells. Development 2011;139: 15-31.
    • (2011) Development , vol.139 , pp. 15-31
    • Saitou, M.1    Kagiwada, S.2    Kurimoto, K.3
  • 59
    • 0036145567 scopus 로고    scopus 로고
    • Dynamic reprogramming of DNA methylation in the early mouse embryo
    • Santos F, Hendrich B, ReikW, Dean W. Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol 2002;241: 172-182.
    • (2002) Dev Biol , vol.241 , pp. 172-182
    • Santos, F.1    Hendrich, B.2    Reik, W.3    Dean, W.4
  • 60
    • 0036836602 scopus 로고    scopus 로고
    • Aberrant methylation patterns at the two-cell stage as an indicator of early developmental failure
    • Shi W, Haaf T. Aberrant methylation patterns at the two-cell stage as an indicator of early developmental failure. Mol Reprod Dev 2002; 63: 329-334.
    • (2002) Mol Reprod Dev , vol.63 , pp. 329-334
    • Shi, W.1    Haaf, T.2
  • 66
    • 79954457998 scopus 로고    scopus 로고
    • Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
    • Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K, Sun YE, Zhang Y. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev 2011;25: 679-684.
    • (2011) Genes Dev , vol.25 , pp. 679-684
    • Wu, H.1    D'Alessio, A.C.2    Ito, S.3    Wang, Z.4    Cui, K.5    Zhao, K.6    Sun, Y.E.7    Zhang, Y.8
  • 67
    • 18044379827 scopus 로고    scopus 로고
    • DNA methylation patterns in human tripronucleate zygotes
    • Xu Y, Zhang JJ, Grifo JA, Krey LC. DNA methylation patterns in human tripronucleate zygotes. Mol Hum Reprod 2005;11: 167-171.
    • (2005) Mol Hum Reprod , vol.11 , pp. 167-171
    • Xu, Y.1    Zhang, J.J.2    Grifo, J.A.3    Krey, L.C.4
  • 69
    • 73449103906 scopus 로고    scopus 로고
    • Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection
    • Yoshizawa Y, Kato M, Hirabayashi M, Hochi S. Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection. Mol Reprod Dev 2010;77: 69-75.
    • (2010) Mol Reprod Dev , vol.77 , pp. 69-75
    • Yoshizawa, Y.1    Kato, M.2    Hirabayashi, M.3    Hochi, S.4
  • 70
    • 35848942124 scopus 로고    scopus 로고
    • Dynamics of DNA-demethylation in early mouse and rat embryos developed in vivo and in vitro
    • Zaitseva I, Zaitsev S, Alenina N, Bader M, Krivokharchenko A. Dynamics of DNA-demethylation in early mouse and rat embryos developed in vivo and in vitro. Mol Reprod Dev 2007;74: 1255-1261.
    • (2007) Mol Reprod Dev , vol.74 , pp. 1255-1261
    • Zaitseva, I.1    Zaitsev, S.2    Alenina, N.3    Bader, M.4    Krivokharchenko, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.