Hybrid organic-inorganic inhibitors of a PDZ interaction that regulates the endocytic fate of CFTR

Angewandte Chemie - International Edition

Volumn 51, Issue 29, 2012, Pages 7217-7220

  Kundu, Rituparna ^a   Cushing, Patrick R ^b,d   Popp, Brian V ^a,c   Zhao, Yu ^b   Madden, Dean R ^b   Ball, Zachary T ^a  

^a RICE UNIVERSITY   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c WEST VIRGINIA UNIVERSITY   (United States)

^d ARQULE INC   (United States)

Author keywords

Cooperative effects; Inhibitors; Metallopeptides; Protein protein interactions; Rhodium

Indexed keywords

COOPERATIVE BINDING; COOPERATIVE EFFECTS; METALLOPEPTIDES; ORGANIC-INORGANIC; POTENT INHIBITION; PROTEIN-PROTEIN INTERACTIONS; SIDE-CHAINS;

BIOCHEMISTRY; CORROSION INHIBITORS; RHODIUM;

PROTEINS;

CARRIER PROTEIN; GOPC PROTEIN, HUMAN; MEMBRANE PROTEIN; ORGANOMETALLIC COMPOUND; PEPTIDE; RHODIUM; TRANSMEMBRANE CONDUCTANCE REGULATOR;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; METABOLISM; MOLECULAR GENETICS; PDZ DOMAIN;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ORGANOMETALLIC COMPOUNDS; PDZ DOMAINS; PEPTIDES; RHODIUM;

EID: 84863665145     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201202291     Document Type: Article

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