Potent inhibitors of HCV-NS3 protease derived from boronic acids

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 1, 2009, Pages 180-183

  Venkatraman, Srikanth ^a   Wu, Wanli ^a   Prongay, Andrew ^a   Girijavallabhan, Viyyoor ^a   George Njoroge, F ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Boronic acid; HCV; NS3 protease

Indexed keywords

BORONIC ACID DERIVATIVE; NONSTRUCTURAL PROTEIN 3; SERINE;

ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HEPATITIS C; HEPATITIS C VIRUS; NONHUMAN; REACTION ANALYSIS; STRUCTURE ANALYSIS;

AMIDES; ANTIVIRAL AGENTS; BORONIC ACIDS; CRYSTALLOGRAPHY, X-RAY; MOLECULAR STRUCTURE; PROTEASE INHIBITORS; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 57849169322     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.124     Document Type: Article

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