Electron paramagnetic resonance characterization of tetrahydrobiopterin radical formation in bacterial nitric oxide synthase compared to mammalian nitric oxide synthase

Biophysical Journal

Volumn 103, Issue 1, 2012, Pages 109-117

  Brunel, Albane ^a,b   Santolini, Jérôme ^a,b   Dorlet, Pierre ^a,b  

^a CNRS   (France)

^b DIF   (France)

Author keywords

(6R) 5,6,7,8 tetrahydro L biopterin; Arg; bacNOS; bacterial NOS like proteins; bsNOS; concerted proton electron transfer; CPET; electron paramagnetic resonance; endothelial nitric oxide synthase; eNOS; EPR; FeIINO; FeIIO2; FeIIINO; ferric heme nitrosyl complex; ferrous heme nitrosyl complex; ferrous heme oxygen complex; H4B; high spin hexacoordinated iron; HS 5c; inducible nitric oxide synthase; iNOS; L arginine; mammalian nitric oxide synthase; mNOS; N hydroxy L arginine; neuronal nitric oxide synthase; nitric oxide; nitric oxide synthase; nNOS; NO; NOHA; NOS; NOS like protein isolated from Bacillus subtilis; NOSoxy; oxygenase domain of NOS

Indexed keywords

5,6,7,8-TETRAHYDROBIOPTERIN; ARGININE; BACTERIAL PROTEIN; BIOPTERIN; DRUG DERIVATIVE; FREE RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; N(OMEGA) HYDROXYARGININE; N(OMEGA)-HYDROXYARGININE; NITRIC OXIDE SYNTHASE; TETRAHYDROBIOPTERIN;

ANIMAL; ARTICLE; BACILLUS SUBTILIS; CHEMISTRY; COMPARATIVE STUDY; ELECTRON SPIN RESONANCE; ENZYMOLOGY; ESCHERICHIA COLI; METABOLISM; OXIDATION REDUCTION REACTION; RAT; SPECIES DIFFERENCE;

ANIMALS; ARGININE; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BIOPTERIN; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; FREE RADICALS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATION-REDUCTION; RATS; SPECIES SPECIFICITY;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 84863488567     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2012.05.032     Document Type: Article

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