Single-turnover of nitric-oxide synthase in the presence of 4-amino-tetrahydrobiopterin: Proposed role for tetrahydrobiopterin as a proton donor

Journal of Biological Chemistry

Volumn 278, Issue 49, 2003, Pages 48602-48610

  Sørlie, Morten ^a   Gorren, Antonius C F ^b   Marchal, Stéphane ^c   Shimizu, Toru ^d   Lange, Reinhard ^c   Andersson, Kristoffer K ^e   Mayer, Bernd ^b  

^a NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^b UNIVERSITY OF GRAZ   (Austria)

^c INSERM   (France)

^d TOHOKU UNIVERSITY   (Japan)

^e UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYSIS; IRON; OXYGEN; PARAMAGNETIC RESONANCE; PROTONS; SPECTROSCOPY; SUBSTRATES; SULFUR COMPOUNDS;

NITRIC-OXIDE SYNTHASES (NOS); OPTICAL SPECTRA; PROTON DONOR; SULFUR LIGANDS;

SYNTHESIS (CHEMICAL);

4 AMINO TETRAHYDROBIOPTERIN; ARGININE; BIOPTERIN; FERROUS ION; HEME; N(G) HYDROXYARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGENASE; PTERIDINE DERIVATIVE; PTERIN DERIVATIVE; TRIHYDROPTERIDINE; UNCLASSIFIED DRUG; 4-AMINO-TETRAHYDROBIOPTERIN; DRUG DERIVATIVE; FREE RADICAL; PROTON;

ARTICLE; BINDING AFFINITY; CATALYSIS; CHEMICAL REACTION; ELECTRON SPIN RESONANCE; ENZYME INHIBITION; OXYGEN AFFINITY; POLARIMETRY; PRIORITY JOURNAL; PROTON TRANSPORT; METABOLISM;

BIOPTERIN; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; NITRIC OXIDE SYNTHASE; PROTONS;

EID: 1542548514     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305682200     Document Type: Article

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