Pterin-centered radical as a mechanistic probe of the second step of nitric oxide synthase

Journal of the American Chemical Society

Volumn 132, Issue 14, 2010, Pages 5105-5113

  Woodward, Joshua J ^a   Nejatyjahromy, Yaser ^b   Britt, R David ^b   Marletta, Michael A ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC SCIENCE; CHEMICAL MECHANISM; CITRULLINE; CO-SUBSTRATE; COFACTORS; COMPLEX NATURE; ELECTRON OXIDATION; EPR SPECTROSCOPY; HEME COFACTOR; HEME DOMAIN; INORGANIC PRODUCTS; L-ARGININE; MECHANISTIC PROBES; NITRIC-OXIDE SYNTHASE; NO FORMATION; OXYGEN ACTIVATIONS; RADICAL DECAY; RADICAL FORMATION; REDOX CYCLING; REDOX-ACTIVE; SINGLE ELECTRON; TETRAHYDROBIOPTERIN;

AMINO ACIDS; COENZYMES; COORDINATION REACTIONS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYMES; HEMOGLOBIN; IRON; MANGANESE; MANGANESE COMPOUNDS; NITRIC OXIDE; OXIDATION; PARAMAGNETIC RESONANCE; PORPHYRINS; POSITIVE IONS; SUBSTRATES;

MOLECULAR OXYGEN;

ARGININE; CITRULLINE; CYSTEINE; CYTOCHROME P450; HEME; INDUCIBLE NITRIC OXIDE SYNTHASE; IRON; MANGANESE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN; PEROXIDE; PTERIN; RADICAL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TETRAHYDROBIOPTERIN;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; ELECTRON; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME SUBSTRATE; OXIDATION; OXIDATION REDUCTION REACTION;

ANIMALS; CATALYSIS; FERROUS COMPOUNDS; FREE RADICALS; MANGANESE COMPOUNDS; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDATION-REDUCTION; PTERINS;

EID: 77950807365     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja909378n     Document Type: Article

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