Evaluation of cytotoxic T-cell activation, chemokine receptors, and adhesion molecules in blood and serum in patients with oral lichen planus

Journal of Oral Pathology and Medicine

Volumn 41, Issue 6, 2012, Pages 484-489

  Namdar Pekiner, Filiz ^a   Demirel, Gulderen Y ^b   Borahan, Mehmet O ^a   Özbayrak, Semih ^a  

^a MARMARA UNIVERSITY   (Turkey)

^b YEDITEPE UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GRANZYME B;

ADULT; APOPTOSIS; ARTICLE; BLOOD SAMPLING; CD8+ T LYMPHOCYTE; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOPHENOTYPING; LICHEN PLANUS; MALE; MOUTH LICHEN PLANUS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANNEXIN A5; ANTIGENS, CD40; APOPTOSIS; B-LYMPHOCYTES; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; COLORING AGENTS; CTLA-4 ANTIGEN; ENZYME INHIBITORS; FEMALE; GRANZYMES; HUMANS; LICHEN PLANUS, ORAL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; PROPIDIUM; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; RECEPTORS, CXCR4; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84863474867     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2012.01130.x     Document Type: Article

References (46)

1. Neppelberg E, Loro LL, Qiordsbakken G, Johannessen AC. Altered CD40 and E-cadherin expression-putative role in oral lichen planus. J Oral Pathol Med 2007; 36: 153-60.
2. Bloor BK, Malik FK, Odell EW, Morgan PR. Quantitative assessment of apoptosis in oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88: 187-95.
3. Neppelberg E, Johannessen AC, Jonsson R. Apoptosis in oral lichen planus. Eur J Oral Sci 2001; 109: 361-4.
4. + T cells in oral Lichen planus predominantly express CCR5 and CXCR3 and carry respective chemokine ligands RANTES/CCL5 and IP-10/CXCL10 in their cytolytic granules. Am J Pathol 2003; 163: 261-8.
5. Santoro A, Majorana A, Bardellini E, et al. Cytotoxic molecule expression and epithelial cell apoptosis in oral and cutaneous lichen planus. Am J Clin Pathol 2004; 121: 758-64.
6. Bascones C, Gonzales-Moles MA, Esparza G, et al. Apoptosis and cell cycle arrest in oral lichen planus hypothesis on their possible influence on its malignant transformation. Arch Oral Biol 2005; 50: 873-81.
7. Weedon D. Apoptosis in lichen planus. Clin Exp Dermatol 1980; 5: 425-30.
8. Shimizu M, Higaki Y, Higaki M, Kawashima M. The role of granzyme B-expressing CD8-positive T cells in apoptosis of keratinocytes in lichen planus. Arch Dermatol Res 1997; 289: 527-32.
9. Shiohara T, Moriya N, Tanaka Y, et al. Immunopathologic study of lichenoid skin disease: correlation between HLA-DR-positive keratinocytes or Langerhans cells and epidermotropic T cells. J Am Acad Dermatol 1988; 18: 67-74.
10. Masson D, Tschopp J. A family of serine esterases in lytic granules of cytolytic Tlymphocytes. Cell 1987; 49: 679-85.
11. Griffiths GM, Mueller C. Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells. Immunol Today 1991; 12: 415-9.
12. Ichimura M, Hiratsuka K, Ogura N, et al. Expression profile of chemokines and chemokine receptors in epithelial cell layers of oral lichen planus. J Oral Pathol Med 2006; 35: 167-74.
13. von Adrian UH, Mempel TR. Homing and cellular traffic in lymph nodes. Nat Rev Immunol 2003; 3: 867-78.
14. Moser B, Loetscher P. Lmyphocyte traffic control by chemokines. Nat Immunol 2001; 2: 123-8.
15. Yoshie O, Imai T, Nomiyama H. Chemokines in immunity. Adv Immunol 2001; 78: 57-110.
16. Sallusto F, Mackay CR, Lanzavecchia A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 1997; 277: 2005-7.
17. Bonecchi R, Bianchi G, Bordignon PP, et al. Differantial expression of chemokine receptors and chemotactic responsiveness of type 1 T hepler cells (Th1s) and Th2s. J Exp Med 1998; 187: 129-34.
18. Alaibac M, Fortina Belloni A, Poletti A, et al. In situ expression of the CTLA-4 receptor in T-cell-mediated inflammatory and neoplastic skin disease. Arc Dermatol Res 2000; 292: 472-4.
19. Scheipers P, Reiser H. Role of the CTLA-4 receptor in T cell activation and immunity. Immunol Res 1998; 18: 103-15.
20. Xu Y, Song G. The role of CD40-CD154 interaction in cell immunoregulation. J Biomed Sci 2004; 11: 426-38.
21. Sugerman PB, Savage NW, Walsh LJ, et al. The pathogenesis of oral lichen planus. Crit Rev Oral Biol Med 2002; 13: 350-65.
22. Ismail SB, Kumar SKS, Zain RB. Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation. J Oral Sci 2007; 49: 89-106.
23. Trapani JA, Davis J, Sutton VR, Smyth MJ. Proapoptotic functions of cytotoxic lymphocyte granule constituents in vitro and in vivo. Curr Opin Immunol 2000; 12: 323-9.
24. Romero V, Andrade F. Non-apoptotic functions of granzymes. Tissue Antigens 2008; 71: 409-16.
25. Gomes MA, Fernandez Bussy R, Schmitt D, Gaucherand M, Maudid G, Thivolet J. Cutaneous immunocompetent cells phenotype and peripheral T cell subpopulations ration in active lichen planus. J Invest Dematol 1982; 78: 334-5.
26. Maudit G, Fernandez Bussy R, Thivolet J. Sequential enumeration of peripheral blood T cell subsets in lichen planus. Clin Exp Dermatol 1984; 9: 256-62.
27. Yamamoto T, Yoneda K, Ueta E, Osaki T. Cellular immunosuppression in oral lichen planus. J Oral Pathol Med 1990; 19: 464-70.
28. Carozzo M, Broccoletti R, Carbone S, Gandolfo S, Garzino P, Cascio G. Phenotypic analysis of peripheral blood cell immunity in Italian patients with different varieties of oral lichen planus. Bull Group Int Rech Sci Stomatol Odontol 1996; 39: 33-8.
29. Al-Fouzan AS, Habib MA, Sallam TH, el-Samahy MH, Rostom AI. Detection of T lymphocytes and T lymphocyte subsets in lichen planus: in situ and in peripheral blood. Int J Dermatol 1996; 35: 426-9.
30. Anthony DA, Andrews DM, Watt SV, Trapani JA, Symth MJ. Functional dissection of the granzyme family: cell death and inflammation. Immunol Rev 2010; 235: 73-92.
31. Costa NL, Gonçalves AS, Souza-Lima NC, et al. Distinct expression of perforin and granzyme B in lip and oral cavity squamous cell carcinoma. J Oral Pathol Med 2011; 40: 380-4.
32. Pimental VN, de Matos LS, Soares TCB, et al. Perforin and granzyme B involved in oral lesions of lichen planus and chronic GVHD. J Oral Pathol Med 2010; 39: 741-6.
33. Trapani JA, Smyth MJ. Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol 2002; 2: 735-47.
34. Ammar M, Mokni M, Boubaker S, El Gaied A, Osman Ben A, Louzir H. Involvement of granzyme B and granulysin in the cytotoxic response in lichen planus. J Cutan Pathol 2008; 35: 630-4.
35. Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002; 2: 277-88.
36. Martinvalet D, Zhu P, Lieberman J. Granzyme A induces caspase- independent mitochondrial damage, a required first step for apoptosis. Immunity 2005; 22: 355-70.
37. Neppelberg E. Pathological mechanisms in oral lichen planus: a study of apoptosis - regulatory proteins and risk markers for malignant transformation. PhD Thesis, Institute of Oral Sciences Oral Pathology and Forensic Odontology and Oral Surgery and Oral Medicine Faculty of Dentistry, University of Bergen, Norway, 2007.
38. Schönbeck U, Libby P. The CD40/CD154 receptor/ligand dyad. Cell Mol Life Sci 2001; 58: 4-43.
39. Villarroel Dorrego M, Speight PM, Barret AW. The immunohistology of CD40 in human oral epithelium in health and disease. J Oral Pathol Med 2006; 35: 268-73.
40. Georgopoulos NT, Steele LP, Thomson MJ, Selby PJ, Southgate J, Trejdosiewicz LK. Anovel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation. Cell Death Differ 2006; 13: 1789-801.
41. Grousson J, Ffrench M, Concha M, Schmitt D, Peguet-Navarro J. CD40 ligation alters the cell cycle of differentiating keratinocytes. J Invest Dermatol 2000; 114: 581-6.
42. Weng AP, Shahsafaei A, Dorfman DM. CXCR4/CD184 Immunoreactivity in T-cell Non-Hodgkin Lymphomas with an overall Th1-Th2+ Immunophenotype. Am J Clin Pathol 2003; 119: 424-30.
43. + T cell activation. J Immunol 2000; 164: 5010-4.
44. Sallusto F, Schaerli P, Loetscher P, et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur J Immunol 1998; 28: 2760-9.
45. Banchereau J, Briere F, Caux C, et al. Immunobiology of dendritic cells. Annu Rev Immunol 2000; 18: 767-811.
46. Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol 2007; 35: 495-516.