-
1
-
-
79953173626
-
Biosynthesis of the immunosuppressants fk506, fk520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate
-
Andexer JN, Kendrew SG, Nur-e-Alam M, Lazos O, Foster TA, Zimmermann AS, Warneck TD, Suthar D, Coates NJ, Koehn FE, Skotnicki JS, Carter GT, Gregory MA, Martin CJ, Moss SJ, Leadlay PF, Wilkinson B (2011) Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate. Proc Natl Acad Sci USA 108:4776-4781
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 4776-4781
-
-
Andexer, J.N.1
Kendrew, S.G.2
Nur-e-Alam, M.3
Lazos, O.4
Foster, T.A.5
Zimmermann, A.S.6
Warneck, T.D.7
Suthar, D.8
Coates, N.J.9
Koehn, F.E.10
Skotnicki, J.S.11
Carter, G.T.12
Gregory, M.A.13
Martin, C.J.14
Moss, S.J.15
Leadlay, P.F.16
Wilkinson, B.17
-
2
-
-
77956468890
-
Streptomyces and saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters
-
Baltz RH (2010) Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters. J Ind Microbiol Biotechnol 37:759-772
-
(2010)
J Ind Microbiol Biotechnol
, vol.37
, pp. 759-772
-
-
Baltz, R.H.1
-
3
-
-
0024996111
-
Biosynthesis of anthraquinones by interspecies cloning of actinorhodin biosynthesis genes in streptomycetes: Clarification of actinorhodin gene functions
-
Bartel PL, Zhu CB, Lampel JS, Dosch DC, Connors NC, Strohl WR, Beale JM Jr., Floss HG (1990) Biosynthesis of anthraquinones by interspecies cloning of actinorhodin biosynthesis genes in streptomycetes: clariWcation of actinorhodin gene functions. J Bacteriol 172:4816-4826 (Pubitemid 20281926)
-
(1990)
Journal of Bacteriology
, vol.172
, Issue.9
, pp. 4816-4826
-
-
Bartel, P.L.1
Zhu, C.-B.2
Lampel, J.S.3
Dosch, D.C.4
Connors, N.C.5
Strohl, W.R.6
Beale Jr., J.M.7
Floss, H.G.8
-
4
-
-
0026645203
-
Plasmid cloning vectors for the conjugal transfer of dna from escherichia coli to streptomyces spp
-
Bierman M, Logan R, O'Brien K, Seno ET, Rao RN, Schoner BE (1992) Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. Gene 116:43-49
-
(1992)
Gene
, vol.116
, pp. 43-49
-
-
Bierman, M.1
Logan, R.2
O'Brien, K.3
Seno, E.T.4
Rao, R.N.5
Schoner, B.E.6
-
5
-
-
0030780191
-
5-Hydroxyaloesaponarin II, a minor blue pigment in an actinorhodin-negative mutant of Streptomyces coelicolor A3(2)
-
Bystrykh LV, Herrema JK, Kruizinga W, Kellogg RM (1997) 5-Hydroxyaloesaponarin II, a minor blue pigment in an actinorhodinnegative mutant of Streptomyces coelicolor A3(2). Biotechnol Appl Biochem 26:195-201 (Pubitemid 27514482)
-
(1997)
Biotechnology and Applied Biochemistry
, vol.26
, Issue.3
, pp. 195-201
-
-
Bystrykh, L.V.1
Herrema, J.K.2
Kruizinga, W.3
Kellogg, R.M.4
-
6
-
-
78650706311
-
Optimization of medium for enhancement of epsilon-poly-l-lysine production by streptomyces sp. M-z18 with glycerol as carbon source
-
Chen X, Tang L, Li S, Liao L, Zhang J, Mao Z (2011) Optimization of medium for enhancement of epsilon-poly-L-lysine production by Streptomyces sp. M-Z18 with glycerol as carbon source. Bioresour Technol 102:1727-1732
-
(2011)
Bioresour Technol
, vol.102
, pp. 1727-1732
-
-
Chen, X.1
Tang, L.2
Li, S.3
Liao, L.4
Zhang, J.5
Mao, Z.6
-
7
-
-
77954626696
-
Heterologousexpression of the biosynthetic gene clusters of coumermycin a(1), clorobiocin and caprazamycins in genetically modiwed streptomyces coelicolor strains
-
Flinspach K, Westrich L, Kaysser L, Siebenberg S, Gomez-Escribano JP, Bibb M, Gust B, Heide L (2010) Heterologousexpression of the biosynthetic gene clusters of coumermycin A(1), clorobiocin and caprazamycins in genetically modiWed Streptomyces coelicolor strains. Biopolymers 93:823-832
-
(2010)
Biopolymers
, vol.93
, pp. 823-832
-
-
Flinspach, K.1
Westrich, L.2
Kaysser, L.3
Siebenberg, S.4
Gomez-Escribano, J.P.5
Bibb, M.6
Gust, B.7
Heide, L.8
-
8
-
-
79951846247
-
Engineering streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters
-
Gomez-Escribano JP, Bibb MJ (2011) Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters. Microb Biotechnol 4:207-215
-
(2011)
Microb Biotechnol
, vol.4
, pp. 207-215
-
-
Gomez-Escribano, J.P.1
Bibb, M.J.2
-
9
-
-
0037452723
-
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
-
DOI 10.1073/pnas.0337542100
-
Gust B, Challis GL, Fowler K, Kieser T, Chater KF (2003) PCRtargeted Streptomyces gene replacement identiWes a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin. Proc Natl Acad Sci USA 100:1541-1546 (Pubitemid 36254483)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.4
, pp. 1541-1546
-
-
Gust, B.1
Challis, G.L.2
Fowler, K.3
Kieser, T.4
Chater, K.F.5
-
10
-
-
34249805418
-
Interspecies DNA microarray analysis identifies WblA as a pleiotropic down-regulator of antibiotic biosynthesis in Streptomyces
-
DOI 10.1128/JB.01789-06
-
Kang SH, Huang J, Lee HN, Hur YA, Cohen SN, Kim ES (2007) Interspecies DNA microarray analysis identiWes WblA as a pleiotropic down-regulator of antibiotic biosynthesis in Streptomyces. J Bacteriol 189:4315-4319 (Pubitemid 46847381)
-
(2007)
Journal of Bacteriology
, vol.189
, Issue.11
, pp. 4315-4319
-
-
Kang, S.-H.1
Huang, J.2
Lee, H.-N.3
Hur, Y.-A.4
Cohen, S.N.5
Kim, E.-S.6
-
11
-
-
70349671401
-
Practical streptomyces genetics: A laboratory manual
-
Norwich
-
Kieser T, Bibb MJ, Chater KF, Buttner MJ, Hopwood DA (2000) Practical Streptomyces genetics: a laboratory manual. John Innes Foundation, Norwich
-
(2000)
John Innes Foundation
-
-
Kieser, T.1
Bibb, M.J.2
Chater, K.F.3
Buttner, M.J.4
Hopwood, D.A.5
-
12
-
-
0028935276
-
Heterologous expression of an engineered biosynthetic pathway: Functional dissection of type ii polyketide synthase components in streptomyces species
-
Kim ES, Cramer KD, Shreve AL, Sherman DH (1995) Heterologous expression of an engineered biosynthetic pathway: functional dissection of type II polyketide synthase components in Streptomyces species. J Bacteriol 177:1202-1207
-
(1995)
J Bacteriol
, vol.177
, pp. 1202-1207
-
-
Kim, E.S.1
Cramer, K.D.2
Shreve, A.L.3
Sherman, D.H.4
-
13
-
-
79953172246
-
Transcriptome analysis of an antibiotic downregulator mutant and synergistic actinorhodin stimulation via disruption of a precursor xux regulator in streptomyces coelicolor
-
Kim SH, Lee HN, Kim HJ, Kim ES (2011) Transcriptome analysis of an antibiotic downregulator mutant and synergistic Actinorhodin stimulation via disruption of a precursor Xux regulator in Streptomyces coelicolor. Appl Environ Microbiol 77:1872-1877
-
(2011)
Appl Environ Microbiol
, vol.77
, pp. 1872-1877
-
-
Kim, S.H.1
Lee, H.N.2
Kim, H.J.3
Kim, E.S.4
-
14
-
-
77249153701
-
Genome-minimized streptomyces host for the heterologous expression of secondary metabolism
-
Komatsu M, Uchiyama T, Omura S, Cane DE, Ikeda H (2010) Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism. Proc Natl Acad Sci USA 107:2646-2651
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2646-2651
-
-
Komatsu, M.1
Uchiyama, T.2
Omura, S.3
Cane, D.E.4
Ikeda, H.5
-
15
-
-
77951616259
-
Putative tetr family transcriptional regulator sco1712 encodes an antibiotic downregulator in streptomyces coelicolor
-
Lee HN, Huang J, Im JH, Kim SH, Noh JH, Cohen SN, Kim ES (2010) Putative TetR family transcriptional regulator SCO1712 encodes an antibiotic downregulator in Streptomyces coelicolor. Appl Environ Microbiol 76:3039-3043
-
(2010)
Appl Environ Microbiol
, vol.76
, pp. 3039-3043
-
-
Lee, H.N.1
Huang, J.2
Im, J.H.3
Kim, S.H.4
Noh, J.H.5
Cohen, S.N.6
Kim, E.S.7
-
16
-
-
13944259584
-
Genetically Modified Bacterial Strains and Novel Bacterial Artificial Chromosome Shuttle Vectors for Constructing Environmental Libraries and Detecting Heterologous Natural Products in Multiple Expression Hosts
-
DOI 10.1128/AEM.70.4.2452-2463.2004
-
Martinez A, Kolvek SJ, Yip CL, Hopke J, Brown KA, MacNeil IA, Osburne MS (2004) Genetically modiWed bacterial strains and novel bacterial artiWcial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts. Appl Environ Microbiol 70:2452-2463 (Pubitemid 38500551)
-
(2004)
Applied and Environmental Microbiology
, vol.70
, Issue.4
, pp. 2452-2463
-
-
Martinez, A.1
Kolvek, S.J.2
Yip, C.L.T.3
Hopke, J.4
Brown, K.A.5
MacNeil, I.A.6
Osburne, M.S.7
-
17
-
-
77955551494
-
Biotechnological doxorubicin production: Pathway and regulation engineering of strains for enhanced production
-
Niraula NP, Kim SH, Sohng JK, Kim ES (2010) Biotechnological doxorubicin production: pathway and regulation engineering of strains for enhanced production. Appl Microbiol Biotechnol 87:1187-1194
-
(2010)
Appl Microbiol Biotechnol
, vol.87
, pp. 1187-1194
-
-
Niraula, N.P.1
Kim, S.H.2
Sohng, J.K.3
Kim, E.S.4
-
18
-
-
50249084003
-
Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering
-
Olano C, Lombó F, Méndez C, Salas JA (2008) Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering. Metab Eng 10:281-292
-
(2008)
Metab Eng
, vol.10
, pp. 281-292
-
-
Olano, C.1
Lombó, F.2
Méndez, C.3
Salas, J.A.4
-
19
-
-
79551488636
-
Mycolic acidcontaining bacteria induce natural-product biosynthesis in streptomyces species
-
Onaka H, Mori Y, Igarashi Y, Furumai T (2011) Mycolic acidcontaining bacteria induce natural-product biosynthesis in Streptomyces species. Appl Environ Microbiol 77:400-406
-
(2011)
Appl Environ Microbiol
, vol.77
, pp. 400-406
-
-
Onaka, H.1
Mori, Y.2
Igarashi, Y.3
Furumai, T.4
-
20
-
-
80052195437
-
Two new doramectin analogs from streptomyces avermitilis neau1069: Fermentation, isolation and structure elucidation
-
Wang XJ, Wang JJ, Wang JD, Zhang J, Xu MD, Xiang WS (2011) Two new doramectin analogs from Streptomyces avermitilis NEAU1069: fermentation, isolation and structure elucidation. J Antibiot (Tokyo) 64:591-594
-
(2011)
J Antibiot (Tokyo)
, Issue.64
, pp. 591-594
-
-
Wang, X.J.1
Wang, J.J.2
Wang, J.D.3
Zhang, J.4
Xu, M.D.5
Xiang, W.S.6
-
21
-
-
79953859655
-
Iso-migrastatin titer improvement in the engineered streptomyces lividans sb11002 strain by optimization of fermentation conditions
-
Wu X, Yang D, Zhu X, Feng Z, Lv Z, Zhang Y, Shen B, Xu Z (2010) Iso-migrastatin titer improvement in the engineered Streptomyces lividans SB11002 strain by optimization of fermentation conditions. Biotechnol Bioprocess Eng 15:664-669
-
(2010)
Biotechnol Bioprocess Eng
, vol.15
, pp. 664-669
-
-
Wu, X.1
Yang, D.2
Zhu, X.3
Feng, Z.4
Lv, Z.5
Zhang, Y.6
Shen, B.7
Xu, Z.8
-
22
-
-
80051981726
-
Identiwcation of the thiazolyl peptide ge37468 gene cluster from streptomyces atcc 55365 and heterologous expression in streptomyces lividans
-
Young TS, Walsh CT (2011) IdentiWcation of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans. Proc Natl Acad Sci USA 108:13053-13058
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 13053-13058
-
-
Young, T.S.1
Walsh, C.T.2
-
23
-
-
65549083361
-
Strategies for the discovery of new natural products by genome mining
-
Zerikly M, Challis GL (2009) Strategies for the discovery of new natural products by genome mining. Chembiochem 10:625-633
-
(2009)
Chembiochem
, vol.10
, pp. 625-633
-
-
Zerikly, M.1
Challis, G.L.2
-
24
-
-
78651431690
-
Heterologous expression of human interleukin-6 in streptomyces lividans tk24 using novel secretory expression vectors
-
Zhu Y, Wang L, Du Y, Wang S, Yu T, Hong B (2011) Heterologous expression of human interleukin-6 in Streptomyces lividans TK24 using novel secretory expression vectors. Biotechnol Lett 33:253-261
-
(2011)
Biotechnol Lett
, vol.33
, pp. 253-261
-
-
Zhu, Y.1
Wang, L.2
Du, Y.3
Wang, S.4
Yu, T.5
Hong, B.6
|