Iso-migrastatin titer improvement in the engineered Streptomyces lividans SB11002 strain by optimization of fermentation conditions

Biotechnology and Bioprocess Engineering

Volumn 15, Issue 4, 2010, Pages 664-669

  Wu, Xueyun ^a,b   Yang, Dong ^b   Zhu, Xiangcheng ^b   Feng, Zhiyang ^c   Lv, Zhengbin ^a   Zhang, Yaozhou ^a   Shen, Ben ^c   Xu, Zhinan ^b  

^a ZHEJIANG SCI TECH UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Fermentation condition; Heterologous expression; Iso migrastatin; Streptomyces lividans SB11002; Streptomyces platensis NRRL 18993

Indexed keywords

BIOSYNTHETIC GENE CLUSTER; FACTOR OPTIMIZATION; FERMENTATION MEDIUM; HETEROLOGOUS EXPRESSION; HETEROLOGOUS PRODUCTION; HETEROLOGOUS SYSTEMS; INORGANIC NITROGEN; ISO-MIGRASTATIN; ORGANIC NITROGEN SOURCES; PLATENSIS; PRODUCTION MEDIUM; STREPTOMYCES LIVIDANS; STREPTOMYCES PLATENSIS; SYSTEMATIC OPTIMIZATION; YEAST EXTRACTS;

BIOCHEMISTRY; BIOSYNTHESIS; GENES; NITROGEN; OPTIMIZATION; ORGANIC CARBON; SUGAR (SUCROSE);

FERMENTATION;

CARBON; ISO MIGRASTATIN; ORGANIC NITROGEN; POLYKETIDE; SUCROSE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BIOENGINEERING; BIOSYNTHESIS; CARBON SOURCE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG STRUCTURE; FERMENTATION MEDIUM; FERMENTATION OPTIMIZATION; GENE CLUSTER; NONHUMAN; STREPTOMYCES; STREPTOMYCES LIVIDANS; STREPTOMYCES PLATENSIS; YEAST;

STREPTOMYCES LIVIDANS; STREPTOMYCES PLATENSIS;

EID: 79953859655     PISSN: 12268372     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12257-009-3129-6     Document Type: Article

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