ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications

Journal of Neuroscience

Volumn 32, Issue 27, 2012, Pages 9133-9142

  Hart, Michael P ^a,b   Gitler, Aaron D ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 2; CASPASE 3; NUCLEIC ACID BINDING PROTEIN; POLYGLUTAMINE; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CONTROLLED STUDY; HEAT SHOCK; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MOTONEURON; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; STRESS;

AMYOTROPHIC LATERAL SCLEROSIS; CASPASE 3; CELL LINE, TUMOR; DNA REPEAT EXPANSION; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; NERVE TISSUE PROTEINS; PEPTIDES; PRIMARY CELL CULTURE; UP-REGULATION;

EID: 84863431578     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0996-12.2012     Document Type: Article

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