Ataxin-2 mediated cell death is dependent on domains downstream of the polyQ repeat

Experimental Neurology

Volumn 208, Issue 2, 2007, Pages 207-215

  Ng, Hiushan ^a   Pulst, Stefan M ^a,b   Huynh, Duong P ^b  

^a BURNS AND ALLEN RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell model; COS1; Cytotoxicity; Golgi dispersion; Ls associated domain; Neurodegenerative disease; Overexpression; PolyQ protein; SCA2; Spinocerebellar ataxia type 2

Indexed keywords

AMINO ACID; ATAXIN 2; MUTANT PROTEIN; NUCLEIC ACID BINDING PROTEIN; POLYGLUTAMINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL DEATH; CELL NUCLEUS INCLUSION BODY; CELL STRUCTURE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DEGENERATIVE DISEASE; GENE DELETION; GOLGI COMPLEX; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SPINOCEREBELLAR DEGENERATION;

AMINO ACID SEQUENCE; ANIMALS; CELL DEATH; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; COS CELLS; GOLGI APPARATUS; MUTATION; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; TRANS-GOLGI NETWORK; TRANSFECTION; TRINUCLEOTIDE REPEAT EXPANSION; UP-REGULATION;

EID: 36049003085     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2007.07.023     Document Type: Article

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