Contribution of phosphates and adenine to the potency of adenophostins at the IP3 receptor: Synthesis of all possible bisphosphates of adenophostin A

Journal of Medicinal Chemistry

Volumn 55, Issue 4, 2012, Pages 1706-1720

  Sureshan, Kana M ^a,c   Riley, Andrew M ^a   Thomas, Mark P ^a   Tovey, Stephen C ^b   Taylor, Colin W ^b   Potter, Barry V L ^a  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEPHOSPHOADENOPHOSTIN A; 3' O (ALPHA DEXTRO GLUCOPYRANOSYL)ADENOSINE 2',4'' BISPHOSPHATE; 3' O (ALPHA DEXTRO GLUCOPYRANOSYL)ADENOSINE 3'',4'' BISPHOSPHATE; 3'' DEPHOSPHOADENOPHOSTIN A; ADENINE; ADENOPHOSTIN A; DEXTRO GLUCOPYRANOSE 3,4 BISPHOSPHATE; GLUCOSE 3,4 BISPHOSPHATE; GLUCOSE DERIVATIVE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; DEPHOSPHORYLATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS;

ADENINE; ADENOSINE; ANIMALS; CALCIUM; CELL LINE; CHICKENS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MODELS, MOLECULAR; ORGANOPHOSPHATES; RATS; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84863401968     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201571p     Document Type: Article

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