Synthesis of potent agonists of the D-myo-inositol 1,4,5-trisphosphate receptor based on clustered disaccharide polyphosphate analogues of adenophostin A

Journal of Medicinal Chemistry

Volumn 43, Issue 17, 2000, Pages 3295-3303

  De Kort, M ^a   Correa, V ^b   Valentijn, A R P M ^a   Van der Marel, G A ^a   Potter, B V L ^c   Taylor, C W ^b   Van Boom, J H ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c University of Bath   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOPHOSTIN A DERIVATIVE; CALCIUM CHANNEL STIMULATING AGENT; DIPHOSTIN; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; PHENYLPHOSTIN; PROPYLPHOSTIN; RIBOPHOSTIN; TETRAPHOSTIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; DEACETYLATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENZYME ACTIVATION; LIVER MEMBRANE; NONHUMAN; PHOSPHORYLATION; RECEPTOR BINDING;

ADENOSINE; ANIMALS; BINDING, COMPETITIVE; CALCIUM; CALCIUM CHANNELS; DISACCHARIDES; INOSITOL 1,4,5-TRISPHOSPHATE; LIGANDS; LIVER; MALE; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEA URCHINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034710711     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000957c     Document Type: Article

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