Development of the cerebellum and cerebellar neural circuits

Developmental Neurobiology

Volumn 72, Issue 3, 2012, Pages 282-301

  Hibi, Masahiko ^a   Shimizu, Takashi ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Adult neurogenesis; Cerebellum; Cerebellum like structure; Hindbrain; Neural circuit; Proneural gene

Indexed keywords

ANATOMY; ARTICLE; BRAIN DEVELOPMENT; BRAIN FUNCTION; CELL COMPARTMENTALIZATION; CELLS; CEREBELLUM; CEREBELLUM NEURAL CIRCUIT; COGNITION; DENDRITE; EFFERENT NERVE; EURYDENDROID CELL; GRANULE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL MEMBRANE POTENTIAL; NERVE REGENERATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RHOMBENCEPHALON; SENSORY NERVE; TELEOST; TISSUE STRUCTURE;

ANIMALS; CEREBELLUM; HUMANS; NERVE NET; NEUROGENESIS; NEURONS; PURKINJE CELLS; ZEBRAFISH;

EID: 84863393127     PISSN: 19328451     EISSN: 10974695     Source Type: Journal    
DOI: 10.1002/dneu.20875     Document Type: Article

References (153)

1. Acampora D, Avantaggiato V, Tuorto F, Simeone A. 1997. Genetic control of brain morphogenesis through Otx gene dosage requirement. Development 124: 3639-3650.
2. Adolf B, Bellipanni G, Huber V, Bally-Cuif L. 2004. atoh1.2 and beta3.1 are two new bHLH-encoding genes expressed in selective precursor cells of the zebrafish anterior hindbrain. Gene Expr Patterns 5: 35-41.
3. Aizawa H, Bianco IH, Hamaoka T, Miyashita T, Uemura O, Concha ML, Russell C, et al. 2005. Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Curr Biol 15: 238-243.
4. Alder J, Cho NK, Hatten ME. 1996. Embryonic precursor cells from the rhombic lip are specified to a cerebellar granule neuron identity. Neuron 17: 389-399.
5. Alonso JR, Arevalo R, Brinon JG, Lara J, Weruaga E, Aijon J. 1992. Parvalbumin immunoreactive neurons and fibres in the teleost cerebellum. Anat Embryol (Berl) 185: 355-361.
6. Altman J, Bayer SA. 1997. Development of the Cerebellar System in Relation to its Evolution, Structure, and Function. Boca Raton, FL: CRC Press.
7. Apps R, Hawkes R. 2009. Cerebellar cortical organization: A one-map hypothesis. Nat Rev Neurosci 10: 670-681.
8. Arrenberg AB, Del Bene F, Baier H. 2009. Optical control of zebrafish behavior with halorhodopsin. Proc Natl Acad Sci USA 106: 17968-17973.
9. Asakawa K, Suster ML, Mizusawa K, Nagayoshi S, Kotani T, Urasaki A, Kishimoto Y, et al. 2008. Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish. Proc Natl Acad Sci USA 105: 1255-1260.
10. Bae YK, Kani S, Shimizu T, Tanabe K, Nojima H, Kimura Y, Higashijima S, et al. 2009. Anatomy of zebrafish cerebellum and screen for mutations affecting its development. Dev Biol 330: 406-426.
11. Balaban CD, McGee DM, Zhou J, Scudder CA. 2002. Responses of primate caudal parabrachial nucleus and Kolliker-fuse nucleus neurons to whole body rotation. J Neurophysiol 88: 3175-3193.
12. Bally-Cuif L, Wassef M. 1994. Ectopic induction and reorganization of Wnt-1 expression in quail/chick chimeras. Development 120: 3379-3394.
13. Beck JC, Gilland E, Tank DW, Baker R. 2004. Quantifying the ontogeny of optokinetic and vestibuloocular behaviors in zebrafish, medaka, and goldfish. J Neurophysiol 92: 3546-3561.
14. Bell CC. 2002. Evolution of cerebellum-like structures. Brain Behav Evol 59: 312-326.
15. Bell CC, Han V, Sawtell NB. 2008. Cerebellum-like structures and their implications for cerebellar function. Annu Rev Neurosci 31: 1-24.
16. Belting HG, Hauptmann G, Meyer D, Abdelilah-Seyfried S, Chitnis A, Eschbach C, Soll I, et al. 2001. spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer. Development 128: 4165-4176.
17. Ben-Arie N, Bellen HJ, Armstrong DL, McCall AE, Gordadze PR, Guo Q, Matzuk MM, et al. 1997. Math1 is essential for genesis of cerebellar granule neurons. Nature 390: 169-172.
18. Boyden ES, Katoh A, Raymond JL. 2004. Cerebellum-dependent learning: The role of multiple plasticity mechanisms. Annu Rev Neurosci 27: 581-609.
19. Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K. 2005. Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci 8: 1263-1268.
20. Brand M, Heisenberg CP, Jiang YJ, Beuchle D, Lun K, Furutani-Seiki M, Granato M, et al. 1996. Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain. Development 123: 179-190.
21. Broccoli V, Boncinelli E, Wurst W. 1999. The caudal limit of Otx2 expression positions the isthmic organizer. Nature 401: 164-168.
22. Brochu G, Maler L, Hawkes R. 1990. Zebrin II: A polypeptide antigen expressed selectively by Purkinje cells reveals compartments in rat and fish cerebellum. J Comp Neurol 291: 538-552.
23. Buckles GR, Thorpe CJ, Ramel MC, Lekven AC. 2004. Combinatorial Wnt control of zebrafish midbrain-hindbrain boundary formation. Mech Dev 121: 437-447.
24. Burgess S, Reim G, Chen W, Hopkins N, Brand M. 2002. The zebrafish spiel-ohne-grenzen (spg) gene encodes the POU domain protein Pou2 related to mammalian Oct4 and is essential for formation of the midbrain and hindbrain, and for pre-gastrula morphogenesis. Development 129: 905-916.
25. Butler AB, Hodos H. 1996. Comparative Vertebrate Neuroanatomy: Evolution and Adaptation. New York: Wiley-Liss.
26. Chaplin N, Tendeng C, Wingate RJ. 2010. Absence of an external germinal layer in zebrafish and shark reveals a distinct, anamniote ground plan of cerebellum development. J Neurosci 30: 3048-3057.
27. Clark WE. 1933. The medical geniculate body and the nucleus isthmi. J Anat 67: 536-548.
28. Croci L, Chung SH, Masserdotti G, Gianola S, Bizzoca A, Gennarini G, Corradi A, et al. 2006. A key role for the HLH transcription factor EBF2COE2, O/E-3 in Purkinje neuron migration and cerebellar cortical topography. Development 133: 2719-2729.
29. Crossley PH, Martinez S, Martin GR. 1996. Midbrain development induced by FGF8 in the chick embryo. Nature 380: 66-68.
30. Curado S, Anderson RM, Jungblut B, Mumm J, Schroeter E, Stainier DY. 2007. Conditional targeted cell ablation in zebrafish: A new tool for regeneration studies. Dev Dyn 236: 1025-1035.
31. Dahmane N, Ruiz i Altaba A. 1999. Sonic hedgehog regulates the growth and patterning of the cerebellum. Development 126: 3089-3100.
32. Danielian PS, McMahon AP. 1996. Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature 383: 332-334.
33. Diaz-Regueira S, Anadon R. 2000. Calretinin expression in specific neuronal systems in the brain of an advanced teleost, the grey mullet (Chelon labrosus). J Comp Neurol 426: 81-105.
34. Dickinson ME, Krumlauf R, McMahon AP. 1994. Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development 120: 1453-1471.
35. Distel M, Wullimann MF, Koster RW. 2009. Optimized Gal4 genetics for permanent gene expression mapping in zebrafish. Proc Natl Acad Sci USA 106: 13365-13370.
36. Douglass AD, Kraves S, Deisseroth K, Schier AF, Engert F. 2008. Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Curr Biol 18: 1133-1137.
37. du Lac S, Raymond JL, Sejnowski TJ, Lisberger SG. 1995. Learning and memory in the vestibulo-ocular reflex. Annu Rev Neurosci 18: 409-441.
38. Elsen GE, Choi LY, Prince VE, Ho RK. 2009. The autism susceptibility gene met regulates zebrafish cerebellar development and facial motor neuron migration. Dev Biol 335: 78-92.
39. Fatemi SH, Halt AR, Realmuto G, Earle J, Kist DA, Thuras P, Merz A. 2002. Purkinje cell size is reduced in cerebellum of patients with autism. Cell Mol Neurobiol 22: 171-175.
40. Finger TE, editor. 1983. The Gustatory System in Teleost Fish. Ann Arbor: University of Michigan Press.
41. Finger TE, editor. 1987. Gustatory Nuclei and Pathways in the Central Nervous System. New York: Wiley.
42. Folgueira M, Anadon R, Yanez J. 2003. Experimental study of the connections of the gustatory system in the rainbow trout, Oncorhynchus mykiss. J Comp Neurol 465: 604-619.
43. Folgueira M, Anadon R, Yanez J. 2006. Afferent and efferent connections of the cerebellum of a salmonid, the rainbow trout (Oncorhynchus mykiss): A tract-tracing study. J Comp Neurol 497: 542-565.
44. Folgueira M, Sueiro C, Rodriguez-Moldes I, Yanez J, Anadon R. 2007. Organization of the torus longitudinalis in the rainbow trout (Oncorhynchus mykiss): An immunohistochemical study of the GABAergic system and a DiI tract-tracing study. J Comp Neurol 503: 348-370.
45. Foucher I, Mione M, Simeone A, Acampora D, Bally-Cuif L, Houart C. 2006. Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants. Development 133: 1891-1900.
46. Geling A, Itoh M, Tallafuss A, Chapouton P, Tannhauser B, Kuwada JY, Chitnis AB, et al. 2003. bHLH transcription factor Her5 links patterning to regional inhibition of neurogenesis at the midbrain-hindbrain boundary. Development 130: 1591-1604.
47. Geling A, Plessy C, Rastegar S, Strahle U, Bally-Cuif L. 2004. Her5 acts as a prepattern factor that blocks neurogenin1 and coe2 expression upstream of Notch to inhibit neurogenesis at the midbrain-hindbrain boundary. Development 131: 1993-2006.
48. Gomez A, Duran E, Salas C, Rodriguez F. 2010. Cerebellum lesion impairs eyeblink-like classical conditioning in goldfish. Neuroscience 166: 49-60.
49. Gonzalez A, ten Donkelaar HJ, de Boer-van Huizen R. 1984. Cerebellar connections in Xenopus laevis. An HRP study. Anat Embryol (Berl) 169: 167-176.
50. Hans S, Kaslin J, Freudenreich D, Brand M. 2009. Temporally-controlled site-specific recombination in zebrafish. PLo S One 4: e4640.
51. Hartfuss E, Galli R, Heins N, Gotz M. 2001. Characterization of CNS precursor subtypes and radial glia. Dev Biol 229: 15-30.
52. Hidalgo-Sanchez M, Millet S, Bloch-Gallego E, Alvarado-Mallart RM. 2005. Specification of the meso-isthmo-cerebellar region: The Otx2/Gbx2 boundary. Brain Res Brain Res Rev 49: 134-149.
53. Hidalgo-Sanchez M, Millet S, Simeone A, Alvarado-Mallart RM. 1999. Comparative analysis of Otx2, Gbx2, Pax2, Fgf8 and Wnt1 gene expressions during the formation of the chick midbrain/hindbrain domain. Mech Dev 81: 175-178.
54. Hirata H, Tomita K, Bessho Y, Kageyama R. 2001. Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain. EMBO J 20: 4454-4466.
55. Hirate Y, Okamoto H. 2006. Canopy1, a novel regulator of FGF signaling around the midbrain-hindbrain boundary in zebrafish. Curr Biol 16: 421-427.
56. Hisano S, Sawada K, Kawano M, Kanemoto M, Xiong G, Mogi K, Sakata-Haga H, et al. 2002. Expression of inorganic phosphate/vesicular glutamate transporters (BNPI/VGLUT1 and DNPI/VGLUT2) in the cerebellum and precerebellar nuclei of the rat. Brain Res Mol Brain Res 107: 23-31.
57. Hoshino M. 2006. Molecular machinery governing GABAergic neuron specification in the cerebellum. Cerebellum 5: 193-198.
58. Hoshino M, Nakamura S, Mori K, Kawauchi T, Terao M, Nishimura YV, Fukuda A, et al. 2005. Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron 47: 201-213.
59. Ikenaga T, Yoshida M, Uematsu K. 2005. Morphology and immunohistochemistry of efferent neurons of the goldfish corpus cerebelli. J Comp Neurol 487: 300-311.
60. Ikenaga T, Yoshida M, Uematsu K. 2006. Cerebellar efferent neurons in teleost fish. Cerebellum 5: 268-274.
61. Ito H, Sakamoto N, Takatsuji K. 1982. Cytoarchitecture, fiber connections, and ultrastructure of nucleus isthmi in a teleost (Navodon modestus) with a special reference to degenerating isthmic afferents from optic tectum and nucleus pretectalis. J Comp Neurol 205: 299-311.
62. Ito H, Yamamoto N, Yoshimoto M, Sawai N, Yang CY, Xue HG, Imura K. 2003. Fiber connections of the torus longitudinalis in a teleost: Cyprinus carpio re-examined. J Comp Neurol 457: 202-211.
63. Ito M. 1982. Cerebellar control of the vestibulo-ocular reflex-Around the flocculus hypothesis. Annu Rev Neurosci 5: 275-296.
64. Ito M. 2002a. Historical review of the significance of the cerebellum and the role of Purkinje cells in motor learning. Ann N Y Acad Sci 978: 273-288.
65. Ito M. 2002b. The molecular organization of cerebellar long-term depression. Nat Rev Neurosci 3: 896-902.
66. Ito M. 2006. Cerebellar circuitry as a neuronal machine. Prog Neurobiol 78: 272-303.
67. Ito M. 2008. Control of mental activities by internal models in the cerebellum. Nat Rev Neurosci 9: 304-313.
68. Jopling C, Sleep E, Raya M, Marti M, Raya A, Belmonte JC. 2010. Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 464: 606-609.
69. Jorntell H, Hansel C. 2006. Synaptic memories upside down: Bidirectional plasticity at cerebellar parallel fiber-Purkinje cell synapses. Neuron 52: 227-238.
70. Joyner AL, Liu A, Millet S. 2000. Otx2, Gbx2 and Fgf8 interact to position and maintain a mid-hindbrain organizer. Curr Opin Cell Biol 12: 736-741.
71. Kani S, Bae YK, Shimizu T, Tanabe K, Satou C, Parsons MJ, Scott E, et al. 2010. Proneural gene-linked neurogenesis in zebrafish cerebellum. Dev Biol 343: 1-17.
72. Kaslin J, Ganz J, Geffarth M, Grandel H, Hans S, Brand M. 2009. Stem cells in the adult zebrafish cerebellum: Initiation and maintenance of a novel stem cell niche. J Neurosci 29: 6142-6153.
73. Katsuyama Y, Oomiya Y, Dekimoto H, Motooka E, Takano A, Kikkawa S, Hibi M, et al. 2007. Expression of zebrafish ROR alpha gene in cerebellar-like structures. Dev Dyn 236: 2694-2701.
74. Kikuchi K, Holdway JE, Werdich AA, Anderson RM, Fang Y, Egnaczyk GF, Evans T, et al. 2010. Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature 464: 601-605.
75. Kim JJ, Thompson RF. 1997. Cerebellar circuits and synaptic mechanisms involved in classical eyeblink conditioning. Trends Neurosci 20: 177-181.
76. Koeppen AH. 2005. The pathogenesis of spinocerebellar ataxia. Cerebellum 4: 62-73.
77. Koster RW, Fraser SE. 2001. Direct imaging of in vivo neuronal migration in the developing cerebellum. Curr Biol 11: 1858-1863.
78. Koster RW, Fraser SE. 2006. FGF signaling mediates regeneration of the differentiating cerebellum through repatterning of the anterior hindbrain and reinitiation of neuronal migration. J Neurosci 26: 7293-7304.
79. Lannoo MJ, Brochu G, Maler L, Hawkes R. 1991a. Zebrin II immunoreactivity in the rat and in the weakly electric teleost Eigenmannia (gymnotiformes) reveals three modes of Purkinje cell development. J Comp Neurol 310: 215-233.
80. Lannoo MJ, Ross L, Maler L, Hawkes R. 1991b. Development of the cerebellum and its extracerebellar Purkinje cell projection in teleost fishes as determined by zebrin II immunocytochemistry. Prog Neurobiol 37: 329-363.
81. Larouche M, Hawkes R. 2006. From clusters to stripes: The developmental origins of adult cerebellar compartmentation. Cerebellum 5: 77-88.
82. Linden DJ, Connor JA. 1993. Cellular mechanisms of long-term depression in the cerebellum. Curr Opin Neurobiol 3: 401-406.
83. Liu A, Losos K, Joyner AL. 1999. FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development 126: 4827-4838.
84. Livet J, Weissman TA, Kang H, Draft RW, Lu J, Bennis RA, Sanes JR, et al. 2007. Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Nature 450: 56-62.
85. Llinas R, Precht W, Kitai ST. 1967. Cerebellar Purkinje cell projection to the peripheral vestibular organ in the frog. Science 158: 1328-1330.
86. Lun K, Brand M. 1998. A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary. Development 125: 3049-3062.
87. Machold R, Fishell G. 2005. Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Neuron 48: 17-24.
88. Malatesta P, Hack MA, Hartfuss E, Kettenmann H, Klinkert W, Kirchhoff F, Gotz M. 2003. Neuronal or glial progeny: Regional differences in radial glia fate. Neuron 37: 751-764.
89. Malatesta P, Hartfuss E, Gotz M. 2000. Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. Development 127: 5253-5263.
90. Mao T, O'Connor DH, Scheuss V, Nakai J, Svoboda K. 2008. Characterization and subcellular targeting of GCaMP-type genetically-encoded calcium indicators. PLoS One 3: e1796.
91. Martinez S, Crossley PH, Cobos I, Rubenstein JL, Martin GR. 1999. FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development 126: 1189-1200.
92. McFarland KA, Topczewska JM, Weidinger G, Dorsky RI, Appel B. 2008. Hh and Wnt signaling regulate formation of olig2+ neurons in the zebrafish cerebellum. Dev Biol 318: 162-171.
93. Medina JF, Garcia KS, Nores WL, Taylor NM, Mauk MD. 2000. Timing mechanisms in the cerebellum: Testing predictions of a large-scale computer simulation. J Neurosci 20: 5516-5525.
94. Meek J, Hafmans TG, Maler L, Hawkes R. 1992. Distribution of zebrin II in the gigantocerebellum of the mormyrid fish Gnathonemus petersii compared with other teleosts. J Comp Neurol 316: 17-31.
95. Meek J, Yang JY, Han VZ, Bell CC. 2008. Morphological analysis of the mormyrid cerebellum using immunohistochemistry, with emphasis on the unusual neuronal organization of the valvula. J Comp Neurol 510: 396-421.
96. Mikami Y, Yoshida T, Matsuda N, Mishina M. 2004. Expression of zebrafish glutamate receptor delta2 in neurons with cerebellum-like wiring. Biochem Biophys Res Commun 322: 168-176.
97. Millet S, Campbell K, Epstein DJ, Losos K, Harris E, Joyner AL. 1999. A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer. Nature 401: 161-164.
98. Miyamura Y, Nakayasu H. 2001. Zonal distribution of Purkinje cells in the zebrafish cerebellum: Analysis by means of a specific monoclonal antibody. Cell Tissue Res 305: 299-305.
99. Miyazaki T, Fukaya M, Shimizu H, Watanabe M. 2003. Subtype switching of vesicular glutamate transporters at parallel fibre-Purkinje cell synapses in developing mouse cerebellum. Eur J Neurosci 17: 2563-2572.
100. Mo W, Chen F, Nechiporuk A, Nicolson T. 2010. Quantification of vestibular-induced eye movements in zebrafish larvae. BMC Neurosci 11: 110.
101. Montgomery JC. 1981. Origin of the parallel fibers in the cerebellar crest overlying the intermediate nucleus of the elasmobranch hindbrain. J Comp Neurol 202: 185-191.
102. Morita Y, Ito H, Masai H. 1980. Central gustatory paths in the crucian carp, Carassius carassius. J Comp Neurol 191: 119-132.
103. Morita Y, Murakami T, Ito H. 1983. Cytoarchitecture and topographic projections of the gustatory centers in a teleost, Carassius carassius. J Comp Neurol 218: 378-394.
104. Mueller T, Wullimann MF. 2002. Expression domains of neuroD (nrd) in the early postembryonic zebrafish brain. Brain Res Bull 57: 377-379.
105. Mufson EJ, Martin TL, Mash DC, Wainer BH, Mesulam MM. 1986. Cholinergic projections from the parabigeminal nucleus (Ch8) to the superior colliculus in the mouse: A combined analysis of horseradish peroxidase transport and choline acetyltransferase immunohistochemistry. Brain Res 370: 144-148.
106. Murakami T, Morita Y. 1987. Morphology and distribution of the projection neurons in the cerebellum in a teleost, Sebastiscus marmoratus. J Comp Neurol 256: 607-623.
107. Nakai J, Ohkura M, Imoto K. 2001. A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein. Nat Biotechnol 19: 137-141.
108. Ninkovic J, Tallafuss A, Leucht C, Topczewski J, Tannhauser B, Solnica-Krezel L, Bally-Cuif L. 2005. Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pair. Development 132: 75-88.
109. Northmore DP. 1991. Visual responses of nucleus isthmi in a teleost fish (Lepomis macrochirus). Vis Res 31: 525-535.
110. Pastor AM, de la Cruz RR, Baker R. 1994. Cerebellar role in adaptation of the goldfish vestibuloocular reflex. J Neurophysiol 72: 1383-1394.
111. Pastor AM, de la Cruz RR, Baker R. 1997. Characterization of Purkinje cells in the goldfish cerebellum during eye movement and adaptive modification of the vestibulo-ocular reflex. Prog Brain Res 114: 359-381.
112. Pfeffer PL, Gerster T, Lun K, Brand M, Busslinger M. 1998. Characterization of three novel members of the zebrafish Pax2/5/8 family: Dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function. Development 125: 3063-3074.
113. Picker A, Brennan C, Reifers F, Clarke JD, Holder N, Brand M. 1999. Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection. Development 126: 2967-2978.
114. Pinto L, Gotz M. 2007. Radial glial cell heterogeneity-The source of diverse progeny in the CNS. Prog Neurobiol 83: 2-23.
115. Pisharath H, Rhee JM, Swanson MA, Leach SD, Parsons MJ. 2007. Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase. Mech Dev 124: 218-229.
116. Ponti G, Peretto P, Bonfanti L. 2008. Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. PLoS One 3: e2366.
117. Punnamoottil B, Kikuta H, Pezeron G, Erceg J, Becker TS, Rinkwitz S. 2008. Enhancer detection in zebrafish permits the identification of neuronal subtypes that express Hox4 paralogs. Dev Dyn 237: 2195-2208.
118. Puzdrowski RL. 1989. Peripheral distribution and central projections of the lateral-line nerves in goldfish, Carassius auratus. Brain Behav Evol 34: 110-131.
119. Reifers F, Adams J, Mason IJ, Schulte-Merker S, Brand M. 2000. Overlapping and distinct functions provided by fgf17, a new zebrafish member of the Fgf8/17/18 subgroup of Fgfs. Mech Dev 99: 39-49.
120. Reifers F, Bohli H, Walsh EC, Crossley PH, Stainier DY, Brand M. 1998. Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125: 2381-2395.
121. Reim G, Brand M. 2002. Spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development. Development 129: 917-933.
122. Rhinn M, Lun K, Ahrendt R, Geffarth M, Brand M. 2009. Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal. Neural Dev 4: 12.
123. Rieger S, Senghaas N, Walch A, Koster RW. 2009. Cadherin-2 controls directional chain migration of cerebellar granule neurons. PLoS Biol 7: e1000240.
124. Rieger S, Volkmann K, Koster RW. 2008. Polysialyltransferase expression is linked to neuronal migration in the developing and adult zebrafish. Dev Dyn 237: 276-285.
125. Rink E, Wullimann MF. 1998. Some forebrain connections of the gustatory system in the goldfish Carassius auratus visualized by separate DiI application to the hypothalamic inferior lobe and the torus lateralis. J Comp Neurol 394: 152-170.
126. Rodriguez F, Duran E, Gomez A, Ocana FM, Alvarez E, Jimenez-Moya F, Broglio C, et al. 2005. Cognitive and emotional functions of the teleost fish cerebellum. Brain Res Bull 66: 365-370.
127. Sakamoto N, Ito H, Ueda S. 1981. Topographic projections between the nucleus isthmi and the optic tectum in a teleost, Navodon modestus. Brain Res 224: 225-234.
128. Sawtell NB, Bell CC. 2008. Adaptive processing in electrosensory systems: Links to cerebellar plasticity and learning. J Physiol Paris 102: 223-232.
129. Schier AF, Neuhauss SC, Harvey M, Malicki J, Solnica-Krezel L, Stainier DY, Zwartkruis F, et al. 1996. Mutations affecting the development of the embryonic zebrafish brain. Development 123: 165-178.
130. Scott EK, Baier H. 2009. The cellular architecture of the larval zebrafish tectum, as revealed by gal4 enhancer trap lines. Front Neural Circuits 3: 13.
131. Scott EK, Mason L, Arrenberg AB, Ziv L, Gosse NJ, Xiao T, Chi NC, et al. 2007. Targeting neural circuitry in zebrafish using GAL4 enhancer trapping. Nat Methods 4: 323-326.
132. Simeone A. 2000. Positioning the isthmic organizer where Otx2 and Gbx2meet. Trends Genet 16: 237-240.
133. Simeone A, Acampora D, Gulisano M, Stornaiuolo A, Boncinelli E. 1992. Nested expression domains of four homeobox genes in developing rostral brain. Nature 358: 687-690.
134. Striedter GF, Northcutt RG. 1989. Two distinct visual pathways through the superficial pretectum in a percomorph teleost. J Comp Neurol 283: 342-354.
135. Suda Y, Matsuo I, Aizawa S. 1997. Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain. Mech Dev 69: 125-141.
136. Tago H, McGeer PL, McGeer EG, Akiyama H, Hersh LB. 1989. Distribution of choline acetyltransferase immunopositive structures in the rat brainstem. Brain Res 495: 271-297.
137. Tanabe K, Kani S, Shimizu T, Bae YK, Abe T, Hibi M. 2010. Atypical PKC regulates primary dendrite specification of cerebellar Purkinje cells by localizaing Golgi apparatus. J Neurosci 30: 16983-16992.
138. Volkmann K, Chen YY, Harris MP, Wullimann MF, Koster RW. 2010. The zebrafish cerebellar upper rhombic lip generates tegmental hindbrain nuclei by long-distance migration in an evolutionary conserved manner. J Comp Neurol 518: 2794-2817.
139. Volkmann K, Rieger S, Babaryka A, Koster RW. 2008. The zebrafish cerebellar rhombic lip is spatially patterned in producing granule cell populations of different functional compartments. Dev Biol 313: 167-180.
140. Voogd J, Pardoe J, Ruigrok TJ, Apps R. 2003. The distribution of climbing and mossy fiber collateral branches from the copula pyramidis and the paramedian lobule: Congruence of climbing fiber cortical zones and the pattern of zebrin banding within the rat cerebellum. J Neurosci 23: 4645-4656.
141. Wallace VA. 1999. Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum. Curr Biol 9: 445-448.
142. Wang VY, Rose MF, Zoghbi HY. 2005. Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum. Neuron 48: 31-43.
143. Wassarman KM, Lewandoski M, Campbell K, Joyner AL, Rubenstein JL, Martinez S, Martin GR. 1997. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development 124: 2923-2934.
144. Wechsler-Reya RJ, Scott MP. 1999. Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron 22: 103-114.
145. Wilson LJ, Wingate RJ. 2006. Temporal identity transition in the avian cerebellar rhombic lip. Dev Biol 297: 508-521.
146. Wilson SW, Brand M, Eisen JS. 2002. Patterning the zebrafish central nervous system. Results Probl Cell Differ 40: 181-215.
147. Wingate R. 2005. Math-Map(ic)s. Neuron 48: 1-4.
148. Woolf NJ. 1991. Cholinergic systems in mammalian brain and spinal cord. Prog Neurobiol 37: 475-524.
149. Wullimann MF, Rupp B, Reichert H. 1996. Neuroanatomy of the Zebrafish Brain: A Topological Atlas. Basel: Birkhäuser Verlag.
150. Wurst W, Bally-Cuif L. 2001. Neural plate patterning: Upstream and downstream of the isthmic organizer. Nat Rev Neurosci 2: 99-108.
151. Xue HG, Yamamoto N, Yang CY, Imura K, Ito H. 2004. Afferent connections of the corpus cerebelli in holocentrid teleosts. Brain Behav Evol 64: 242-258.
152. Yamada M, Terao M, Terashima T, Fujiyama T, Kawaguchi Y, Nabeshima Y, Hoshino M. 2007. Origin of climbing fiber neurons and their developmental dependence on Ptf1a. J Neurosci 27: 10924-10934.
153. Zupanc GK, Hinsch K, Gage FH. 2005. Proliferation, migration, neuronal differentiation, and long-term survival of new cells in the adult zebrafish brain. J Comp Neurol 488: 290-319.