Overlapping and distinct functions provided by fgf17, a new zebrafish member of the Fgf8/17/18 subgroup of Fgfs

Mechanisms of Development

Volumn 99, Issue 1-2, 2000, Pages 39-49

  Reifers, Frank ^a   Adams, Jan ^b   Mason, Ivor J ^c   Schulte Merker, Stefan ^b   Brand, Michael ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Danio rerio; Fgf17; Fgf18; Fgf8; Hindbrain; Isthmus; Midbrain; Midbrain hindbrain boundary; Neurogenesis; Optic stalk; Somites; Zebrafish

Indexed keywords

FIBROBLAST GROWTH FACTOR 17; FIBROBLAST GROWTH FACTOR 8; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DNA SEQUENCE; MORPHOGENESIS; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; SIGNAL TRANSDUCTION; VISUAL SYSTEM; ZEBRA FISH;

AMINO ACID SEQUENCE; ANIMALS; CHROMOSOME MAPPING; CLONING, MOLECULAR; CONSERVED SEQUENCE; DNA, COMPLEMENTARY; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; GASTRULA; IN SITU HYBRIDIZATION; MESENCEPHALON; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PHYLOGENY; RHOMBENCEPHALON; RNA; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SOMITES; TIME FACTORS; UP-REGULATION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 0033728603     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(00)00475-5     Document Type: Article

References (71)

1. Genetic control of brain morphogenesis through Otx gene dosage requirement
2. Fate and potentialities of the avian mesencephalic/metencephalic neuroepithelium
3. A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain
4. Relationship between Wnt-1 and En-2 expression domains during early development of normal and ectopic met-mesencephalon
5. Determination events in the nervous system of the vertebrate embryo
6. The FGF family of growth factors and oncogenes
7. Genetic analysis of early development of a vertebrate nervous system in the zebrafish, Danio rerio
8. Keeping and raising zebrafish
9. Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain
10. Caudalization of neural fate by tissue recombination and bFGF
11. The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
12. Midbrain development induced by FGF8 in the chick embryo
13. The mouse Pax21Neu mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye and kidney
14. A role for Fgf-8 in the dorsoventral patterning of the zebrafish gastrula
15. The cellular environment controls the expression of engrailed-like protein in the cranial neuroepithelium of quail-chick chimeric embryos
16. A radiation hybrid map of the zebrafish genome
17. Identification and characterization of a novel member of the fibroblast growth factor family
18. Analysis of FGF function in normal and no tail zebrafish embryos reveals separate mechanisms for formation of the trunk and the tail
19. Fgf-8 expression in the post-gastrulation mouse suggests roles in the development of the face, limbs and central nervous system
20. Zebrafish aussicht mutants exhibit widespread overexpression of ace(fgf8) and coincident defects in CNS development
21. Structure and expression of a novel fibroblast growth factor, FGF-17, preferentially expressed in the embryonic brain
22. A small population of anterior cells patterns the forebrain during zebrafish gastrulation
23. Structural and functional diversity in the Fgf receptor multigene family
24. Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development
25. The zebrafish Fgf-3 gene: cDNA sequence, transcript structure and genomic organization
26. Stages of embryonic development of the zebrafish
27. Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis
28. Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation
29. Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern
30. Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain
31. Patterning the vertebrate neuraxis
32. A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary
33. A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth
34. Expression of Fgf-3 in relation to hindbrain segmentation, otic pit position and pharyngeal arch morphology in normal and retinoic acid-exposed mouse embryos
35. Patterning of the embryonic avian midbrain after experimental inversions: A polarizing activity from the isthmus
36. Induction of a mesencephalic phenotype in the 2-day-old chick prosencephalon is preceded by the early expression of the homeobox gene en
37. Induction of ectopic engrailed expression and fate change in avian rhombomeres: Intersegmental boundaries as barriers
38. FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression
39. - mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum
40. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination
41. Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants
42. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
43. Rostrocaudal polarity formation of chick optic tectum
44. Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain
45. Structure and expression of the mRNA encoding a novel fibroblast growth factor, FGF-18
46. Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis
47. FGFs, heparan sulfate and FGFRs: Complex interactions essential for development
48. Receptor specificity of the fibroblast growth factor family
49. Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development
50. Characterization of three novel members of the zebrafish Pax2/5/8 family: Dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function
51. Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection
52. The midbrain-hindbrain junction: A model system for brain regionalization through morphogenetic neuroepithelial interactions
53. Fgf8 is mutated in zebrafish acerebellar mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis
54. Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar)
55. Mutation of the Pax2 gene in a family with optic nerve colobomas, renal abnormalities and vesicouretal reflux
56. Mutations affecting development of the embryonic zebrafish brain
57. Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain
58. Ace/Fgf8 is required for forebrain commissure formation and patterning of the telencephalon
59. Inductive interactions direct early regionalization of the mouse forebrain
60. Developmental expression of the Xenopus int-2 (FGF-3) gene: Activation by mesodermal and neural induction
61. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
62. Pax-2 controls multiple steps of urogenital development
63. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
64. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function
65. Early mesencephalon/metencephalon patterning and development of the cerebellum
66. Regional specification during cerebellar development
67. Developmental regulation of zebrafish myoD in wild-type, no tail and spadetail embryos
68. Multiple developmental defects in Engrailed-1 mutant mice: An early mid-hindbrain deletion and patterning defects in forelimbs and sternum
69. Genomic structure, mapping, activity and expression of fibroblast growth factor 17
70. Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures