메뉴 건너뛰기




Volumn 40, Issue 4, 2012, Pages 1267-1276

Blockade of irradiation-induced autophagosome formation impairs proliferation but does not enhance cell death in HCT-116 human colorectal carcinoma cells

Author keywords

Autophagy; Cell signaling; Colorectal cancer; Proliferation; Radiotherapy

Indexed keywords

BOVINE SERUM ALBUMIN; GOLD; LIPOCORTIN 5; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 84863383951     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1329     Document Type: Article
Times cited : (3)

References (46)
  • 1
    • 65349155174 scopus 로고    scopus 로고
    • Early endosomes and endosomal coatomer are required for autophagy
    • Razi M, Chan EY and Tooze SA: Early endosomes and endosomal coatomer are required for autophagy. J Cell Biol 185: 305-321, 2009.
    • (2009) J Cell Biol , vol.185 , pp. 305-321
    • Razi, M.1    Chan, E.Y.2    Tooze, S.A.3
  • 2
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • DOI 10.1016/S1534-5807(04)00099-1, PII S1534580704000991
    • Levine B and Klionsky DJ: Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477, 2004. (Pubitemid 38456176)
    • (2004) Developmental Cell , vol.6 , Issue.4 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 6
    • 40449086885 scopus 로고    scopus 로고
    • Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy
    • DOI 10.1158/0008-5472.CAN-07-0562
    • Apel A, Herr I, Schwarz H, Rodemann HP and Mayer A: Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res 68: 1485-1494, 2008. (Pubitemid 351346857)
    • (2008) Cancer Research , vol.68 , Issue.5 , pp. 1485-1494
    • Apel, A.1    Herr, I.2    Schwarz, H.3    Rodemann, H.P.4    Mayer, A.5
  • 8
    • 0029741890 scopus 로고    scopus 로고
    • Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: The role of autophagy
    • Bursch W, Ellinger A, Kienzl H, et al: Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 17: 1595-1607, 1996. (Pubitemid 26280381)
    • (1996) Carcinogenesis , vol.17 , Issue.8 , pp. 1595-1607
    • Bursch, W.1    Ellinger, A.2    Kienzl, H.3    Torok, L.4    Pandey, S.5    Sikorska, M.6    Walker, R.7    Hermann, R.S.8
  • 9
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • DOI 10.1038/nrc1692, PII N1692
    • Kondo Y, Kanzawa T, Sawaya R and Kondo S: The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5: 726-734, 2005. (Pubitemid 41486365)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.9 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4
  • 14
    • 33746166864 scopus 로고    scopus 로고
    • Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity
    • DOI 10.1158/0008-5472.CAN-05-3557
    • Corcelle E, Nebout M, Bekri S, et al: Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity. Cancer Res 66: 6861-6870, 2006. (Pubitemid 44085647)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6861-6870
    • Corcelle, E.1    Nebout, M.2    Bekri, S.3    Gauthier, N.4    Hofman, P.5    Poujeol, P.6    Fenichel, P.7    Mograbi, B.8
  • 15
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • Klionsky DJ and Erm SD: Autophagy as a regulated pathway of cellular degradation. Science 290: 1717-172, 2000.
    • (2000) Science , vol.290 , pp. 1717-2172
    • Klionsky, D.J.1    Erm, S.D.2
  • 17
    • 2542628931 scopus 로고    scopus 로고
    • Ras is involved in the negative control of autophagy through the class I PI3-kinase
    • DOI 10.1038/sj.onc.1207539
    • Furuta S, Hidaka E, Ogata A, Yokota S and Kamata T: RAS is involved in the negative control of autophagy through the class IP3-kinase. Oncogene 23: 3898-3904, 2004. (Pubitemid 38747918)
    • (2004) Oncogene , vol.23 , Issue.22 , pp. 3898-3904
    • Furuta, S.1    Hidaka, E.2    Ogata, A.3    Yokota, S.4    Kamata, T.5
  • 18
    • 0035929650 scopus 로고    scopus 로고
    • The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
    • Arico S, Petiot A, Bauvy C, et al: The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem 276: 35243-35246, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 35243-35246
    • Arico, S.1    Petiot, A.2    Bauvy, C.3
  • 19
    • 0034672063 scopus 로고    scopus 로고
    • Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells
    • DOI 10.1074/jbc.M006198200
    • Ogier-Denis E, Pattingre S, Benna J and Codogno P: Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells. J Biol Chem 275: 39090-39095, 2000. (Pubitemid 32058923)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 39090-39095
    • Ogier-Denis, E.1    Pattingre, S.2    El, B.J.3    Codogno, P.4
  • 21
    • 0033118475 scopus 로고    scopus 로고
    • Apoptosis, p53, and tumor cell sensitivity to anticancer agents
    • Brown M and Wounters BG: Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res 59: 1391-1399, 1999.
    • (1999) Cancer Res , vol.59 , pp. 1391-1399
    • Brown, M.1    Wounters, B.G.2
  • 22
    • 0033579297 scopus 로고    scopus 로고
    • Does cancer therapy trigger cell suicide?
    • Finkel E: Does cancer therapy trigger cell suicide? Science 286: 2256-2258, 1999.
    • (1999) Science , vol.286 , pp. 2256-2258
    • Finkel, E.1
  • 23
    • 26444573721 scopus 로고    scopus 로고
    • Radiation induced MMP expression from rectal cancer is short lived but contributes to in vitro invasion
    • Speake WJ, Dean RA, Kumar A, Morris TM, Scholefield SA and Watson JH: Radiation induced MMP expression from rectal cancer is short lived but contributes to in vitro invasion. Eur J Surg Oncol 31: 869-871, 2005.
    • (2005) Eur J Surg Oncol , vol.31 , pp. 869-871
    • Speake, W.J.1    Dean, R.A.2    Kumar, A.3    Morris, T.M.4    Scholefield, S.A.5    Watson, J.H.6
  • 24
    • 0031593675 scopus 로고    scopus 로고
    • 1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
    • Yamamoto A, Tagawa Y, Yoshimori T, Moriyama Y, Masaki R and Tashiro Y: Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct Funct 23: 33-42, 1998. (Pubitemid 28223394)
    • (1998) Cell Structure and Function , vol.23 , Issue.1 , pp. 33-42
    • Yamamoto, A.1    Tagawa, Y.2    Yoshimori, T.3    Moriyama, Y.4    Masaki, R.5    Tashiro, Y.6
  • 25
    • 0028856914 scopus 로고
    • Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: Effects of vinblastine and asparagine on vacuole distributions
    • Fengsrud M, Roos N, Berg T, Liou W, Slot JW and Seglen PO: Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuole distributions. Exp Cell Res 221: 504-519, 1995.
    • (1995) Exp Cell Res , vol.221 , pp. 504-519
    • Fengsrud, M.1    Roos, N.2    Berg, T.3    Liou, W.4    Slot, J.W.5    Seglen, P.O.6
  • 26
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, Mizushima N, Ueno T, et al: LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19: 5720-5728, 2003.
    • (2003) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3
  • 27
    • 66349112689 scopus 로고    scopus 로고
    • Radiation-induced autophagy in normal and cancer cells: Towards novel cytoprotection and radio-sensitization policies?
    • Zois CE and Koukourakis MI: Radiation-induced autophagy in normal and cancer cells: towards novel cytoprotection and radio-sensitization policies? Autophagy 5: 442-450, 2009.
    • (2009) Autophagy , vol.5 , pp. 442-450
    • Zois, C.E.1    Koukourakis, M.I.2
  • 28
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: An innocent convict?
    • DOI 10.1172/JCI26390
    • Levine B and Yuan J: Autophagy in cell death: an innocent convict? J Clin Invest 115: 2679-2688, 2005. (Pubitemid 41434392)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 29
    • 77953289524 scopus 로고    scopus 로고
    • Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model
    • Li J, Hou N, Faried A, Tsutsumi S and Kuwano H: Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. Eur J Cancer 46: 1900-1909, 2010.
    • (2010) Eur J Cancer , vol.46 , pp. 1900-1909
    • Li, J.1    Hou, N.2    Faried, A.3    Tsutsumi, S.4    Kuwano, H.5
  • 30
    • 33645944960 scopus 로고    scopus 로고
    • Autophagy and cancer therapy
    • Kondo Y and Kondo S: Autophagy and cancer therapy. Autophagy 2: 85-90, 2006.
    • (2006) Autophagy , vol.2 , pp. 85-90
    • Kondo, Y.1    Kondo, S.2
  • 31
    • 28244475972 scopus 로고    scopus 로고
    • Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells
    • Paglin S, Lee NY, Nakar C, et al: Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells. Cancer Res 65: 11061-110702, 2005.
    • (2005) Cancer Res , vol.65 , pp. 11061-110702
    • Paglin, S.1    Lee, N.Y.2    Nakar, C.3
  • 34
    • 78650215702 scopus 로고    scopus 로고
    • Harnessing the complexity of DNA damage response pathways to improve cancer treatment outcomes
    • Al-Ejeh F, Kumar R, Wiegmans A, Lakhani SR, Brown MP and Khanna KK: Harnessing the complexity of DNA damage response pathways to improve cancer treatment outcomes. Oncogene 29: 6085-6098, 2010.
    • (2010) Oncogene , vol.29 , pp. 6085-6098
    • Al-Ejeh, F.1    Kumar, R.2    Wiegmans, A.3    Lakhani, S.R.4    Brown, M.P.5    Khanna, K.K.6
  • 35
    • 54249107573 scopus 로고    scopus 로고
    • Regulation of estrogenic effects by beclin 1 in breast cancer cells
    • John S, Nayvelt I, Hsu HC, Yang P, Liu W and Das GM: Regulation of estrogenic effects by beclin 1 in breast cancer cells. Cancer Res 68: 7855-7863, 2008.
    • (2008) Cancer Res , vol.68 , pp. 7855-7863
    • John, S.1    Nayvelt, I.2    Hsu, H.C.3    Yang, P.4    Liu, W.5    Das, G.M.6
  • 36
    • 26844531363 scopus 로고    scopus 로고
    • Maturation of autophagic vacuoles in mammalian cells
    • Eskelinen EL: Maturation of autophagic vacuoles in mammalian cells. Autophagy 1: 1-10, 2005.
    • (2005) Autophagy , vol.1 , pp. 1-10
    • Eskelinen, E.L.1
  • 37
    • 77950462712 scopus 로고    scopus 로고
    • Where do they come from? Insights into autophagosome formation
    • Hamasaki M and Yoshimori T: Where do they come from? Insights into autophagosome formation. FEBS Lett 584: 1296-1301, 2010.
    • (2010) FEBS Lett , vol.584 , pp. 1296-1301
    • Hamasaki, M.1    Yoshimori, T.2
  • 38
    • 70349969648 scopus 로고    scopus 로고
    • Apoptosis and autophagy: Targeting autophagy signaling in cancer cells - 'trick or treats'?
    • Corcelle EA, Puustinen P and Jäättlelä M: Apoptosis and autophagy: targeting autophagy signaling in cancer cells - 'trick or treats'? FEBS J 276: 6084-6096, 2009.
    • (2009) FEBS J , vol.276 , pp. 6084-6096
    • Corcelle, E.A.1    Puustinen, P.2    Jäättlelä, M.3
  • 39
    • 33745095268 scopus 로고    scopus 로고
    • Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer
    • DOI 10.1158/1535-7163.MCT-05-0400
    • Albert JM, Cao KW and Lu B: Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer. Mol Cancer Ther 5: 1183-1189, 2006. (Pubitemid 43881310)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.5 , pp. 1183-1189
    • Albert, J.M.1    Kim, K.W.2    Cao, C.3    Lu, B.4
  • 40
    • 0032815618 scopus 로고    scopus 로고
    • Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
    • Dent P, Reardon DB, Park JS, et al: Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Mol Biol Cell 10: 2493-2506, 1999. (Pubitemid 29393505)
    • (1999) Molecular Biology of the Cell , vol.10 , Issue.8 , pp. 2493-2506
    • Dent, P.1    Reardon, D.B.2    Park, J.S.3    Bowers, G.4    Logsdon, C.5    Valerie, K.6    Schmidt-Ullrich, R.7
  • 42
    • 0346753579 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase accelerates autophagic cell death during glucose deprivation in the rat cardiomyocyte-derived cell line H9c2
    • DOI 10.1038/sj.onc.1207197
    • Aki T, Yamaguchi K, Fujimiya T and Mizukami Y: Phospho-inositide 3-kinase accelerates autophagic cell death during glucose deprivation in the rat cardiomyocyte-derived cell line H9c2. Oncogene 22: 8529-8535, 2003. (Pubitemid 37523905)
    • (2003) Oncogene , vol.22 , Issue.52 , pp. 8529-8535
    • Aki, T.1    Yamaguchi, K.2    Fujimiya, T.3    Mizukami, Y.4
  • 43
    • 17144427728 scopus 로고    scopus 로고
    • Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
    • Takeuchi H, Kondo Y, Fujiwara K, et al: Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Res 65: 3336-3346, 2005. (Pubitemid 40524618)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3336-3346
    • Takeuchi, H.1    Kondo, Y.2    Fujiwara, K.3    Kanzawa, T.4    Aoki, H.5    Mills, G.B.6    Kondo, S.7
  • 45
    • 53749104349 scopus 로고    scopus 로고
    • Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
    • Degtyarev M, De Mazi è re A, Orr C, et al: Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. J Cell Biol 183: 101-116, 2008.
    • (2008) J Cell Biol , vol.183 , pp. 101-116
    • Degtyarev, M.1    De Mazière, A.2    Orr, C.3
  • 46
    • 84861828977 scopus 로고    scopus 로고
    • Neuronal autophagy as a mediator of life and death: Contrasting roles in chronic neurodegenerative and acute neural disorders
    • doi: 10.1177/1073858411404948
    • Puyal J, Ginet V, Grishchuk Y, Truttmann AC and Clarke PG: Neuronal autophagy as a mediator of life and death: contrasting roles in chronic neurodegenerative and acute neural disorders. Neuroscientist 2011. doi: 10.1177/1073858411404948.
    • (2011) Neuroscientist
    • Puyal, J.1    Ginet, V.2    Grishchuk, Y.3    Truttmann, A.C.4    Clarke, P.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.