메뉴 건너뛰기




Volumn 6, Issue 1, 2010, Pages 46-60

Bacillus calmette-guerin cell wall cytoskeleton enhances colon cancer radiosensitivity through autophagy

Author keywords

Autophagy; BCG cell wall skeleton; JNK; Radiosensitization; Reactive oxygen species; Toll like receptor

Indexed keywords

BCG VACCINE; BENZYLOXYCARBONYL VALYLALANYLASPARTIC ACID FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; CELL WALL SKELETON; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

EID: 75149136162     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.6.1.10325     Document Type: Article
Times cited : (71)

References (64)
  • 3
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protractedinfusion fluorouracil with radiation therapy after curative surgery
    • O'Connell MJ, Martenson JA, Wieand HS, Krook JE, Macdonald JS, Haller DG, et al. Improving adjuvant therapy for rectal cancer by combining protractedinfusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 1994; 331:502-7.
    • (1994) N Engl J Med , vol.331 , pp. 502-507
    • O'Connell, M.J.1    Martenson, J.A.2    Wieand, H.S.3    Krook, J.E.4    Macdonald, J.S.5    Haller, D.G.6
  • 4
    • 0030993414 scopus 로고    scopus 로고
    • Preoperative 5-FU, low-dose leucovorin, and radiation therapy for locally advanced and unresectable rectal cancer
    • Minsky BD, Cohen AM, Enker WE, Saltz L, Guillem JG, Paty PB, et al. Preoperative 5-FU, low-dose leucovorin, and radiation therapy for locally advanced and unresectable rectal cancer. Int J Radiat Oncol Biol Phys 1997; 37:289-95.
    • (1997) Int J Radiat Oncol Biol Phys , vol.37 , pp. 289-295
    • Minsky, B.D.1    Cohen, A.M.2    Enker, W.E.3    Saltz, L.4    Guillem, J.G.5    Paty, P.B.6
  • 5
    • 0036804343 scopus 로고    scopus 로고
    • Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer
    • Kim JS, Kim JS, Cho MJ, Song KS, Yoon WH. Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 2002; 54:403-8.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 403-408
    • Kim, J.S.1    Kim, J.S.2    Cho, M.J.3    Song, K.S.4    Yoon, W.H.5
  • 6
    • 0035340318 scopus 로고    scopus 로고
    • Addition of oxaliplatin to continuous fluorouracil, l-folinic acid, and concomitant radiotherapy in rectal cancer: The Lyon R 97-03 phase I trial
    • Freyer G, Bossard N, Romestaing P, Mornex F, Chapet O, Trillet-Lenoir V, Gérard JP. Addition of oxaliplatin to continuous fluorouracil, l-folinic acid, and concomitant radiotherapy in rectal cancer: the Lyon R 97-03 phase I trial. J Clin Oncol 2001; 19:2433-8.
    • (2001) J Clin Oncol , vol.19 , pp. 2433-2438
    • Freyer, G.1    Bossard, N.2    Romestaing, P.3    Mornex, F.4    Chapet, O.5    Trillet-Lenoir, V.6    Gérard, J.P.7
  • 7
    • 0037445116 scopus 로고    scopus 로고
    • Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: The Lyon R0-04 phase II trial
    • Gerard JP, Chapet O, Nemoz C, Romestaing P, Mornex F, Coquard R, et al. Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: the Lyon R0-04 phase II trial. J Clin Oncol 2003; 21:1119-24.
    • (2003) J Clin Oncol , vol.21 , pp. 1119-1124
    • Gerard, J.P.1    Chapet, O.2    Nemoz, C.3    Romestaing, P.4    Mornex, F.5    Coquard, R.6
  • 8
    • 0347298702 scopus 로고    scopus 로고
    • Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer
    • Mehta VK, Cho C, Ford JM, Jambalos C, Poen J, Koong A, et al. Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer. Int J Radiat Oncol Biol Phys 2003; 55:132-7.
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 132-137
    • Mehta, V.K.1    Cho, C.2    Ford, J.M.3    Jambalos, C.4    Poen, J.5    Koong, A.6
  • 9
    • 0034162780 scopus 로고    scopus 로고
    • Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor
    • Kishi K, Petersen S, Petersen C, Hunter N, Mason K, Masferrer JL, et al. Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor. Cancer Res 2000; 60:1326-31.
    • (2000) Cancer Res , vol.60 , pp. 1326-1331
    • Kishi, K.1    Petersen, S.2    Petersen, C.3    Hunter, N.4    Mason, K.5    Masferrer, J.L.6
  • 11
    • 39749153032 scopus 로고    scopus 로고
    • Phase I-II trial of cetuximab, capecitabine, oxaliplatin and radiotherapy as preoperative treatment in rectal cancer
    • Rödel C, Arnold D, Hipp M, Liersch T, Dellas K, Iesalnieks I, et al. Phase I-II trial of cetuximab, capecitabine, oxaliplatin and radiotherapy as preoperative treatment in rectal cancer. Int J Radiat Oncol Biol Phys 2008; 70:1081-6.
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , pp. 1081-1086
    • Rödel, C.1    Arnold, D.2    Hipp, M.3    Liersch, T.4    Dellas, K.5    Iesalnieks, I.6
  • 13
    • 33645944960 scopus 로고    scopus 로고
    • Autophagy and cancer therapy
    • Kondo Y, Kondo S. Autophagy and cancer therapy. Autophagy 2006; 2:85-90.
    • (2006) Autophagy , vol.2 , pp. 85-90
    • Kondo, Y.1    Kondo, S.2
  • 14
    • 0035863399 scopus 로고    scopus 로고
    • A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
    • Paglin S, Hollister T, Delohery T, Hackett N, McMahill M, Sphicas E, et al. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 2001; 61:439-44.
    • (2001) Cancer Res , vol.61 , pp. 439-444
    • Paglin, S.1    Hollister, T.2    Delohery, T.3    Hackett, N.4    McMahill, M.5    Sphicas, E.6
  • 15
    • 33845974091 scopus 로고    scopus 로고
    • Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling
    • Kim KW, Mutter RW, Cao C, Albert JM, Freeman M, Hallahan DE, Lu B. Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling. J Biol Chem 2006; 281:36883-90.
    • (2006) J Biol Chem , vol.281 , pp. 36883-36890
    • Kim, K.W.1    Mutter, R.W.2    Cao, C.3    Albert, J.M.4    Freeman, M.5    Hallahan, D.E.6    Lu, B.7
  • 16
    • 20144373772 scopus 로고    scopus 로고
    • Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy
    • Daido S, Yamamoto A, Fujiwara K, Sawaya R, Kondo S, Kondo Y. Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy. Cancer Res 2005; 65:4368-75.
    • (2005) Cancer Res , vol.65 , pp. 4368-4375
    • Daido, S.1    Yamamoto, A.2    Fujiwara, K.3    Sawaya, R.4    Kondo, S.5    Kondo, Y.6
  • 17
    • 0034995057 scopus 로고    scopus 로고
    • Development of immunoadjuvants for immunotherapy of cancer
    • Azuma I, Seya T. Development of immunoadjuvants for immunotherapy of cancer. Int Immunopharmacol 2001; 1:1249-59.
    • (2001) Int Immunopharmacol , vol.1 , pp. 1249-1259
    • Azuma, I.1    Seya, T.2
  • 18
    • 0036065826 scopus 로고    scopus 로고
    • Structural-functional relationship of pathogen-associated molecular patterns: Lessons from BCG cell wall skeleton and mycoplasma lipoprotein M161Ag
    • Seya T, Matsumoto M, Tsuji S, Begum NA, Azuma I, Toyoshima K. Structural-functional relationship of pathogen-associated molecular patterns: lessons from BCG cell wall skeleton and mycoplasma lipoprotein M161Ag. Microbes Infect 2002; 4:955-61.
    • (2002) Microbes Infect , vol.4 , pp. 955-961
    • Seya, T.1    Matsumoto, M.2    Tsuji, S.3    Begum, N.A.4    Azuma, I.5    Toyoshima, K.6
  • 19
    • 0016203576 scopus 로고
    • Immunotherapy of cancer: Regression of established intradermal tumors after intralesional injection of mycobacterial cell walls attached to oil droplets
    • Zbar B, Ribi E, Meyer T, Azuma I, Rapp HJ. Immunotherapy of cancer: regression of established intradermal tumors after intralesional injection of mycobacterial cell walls attached to oil droplets. J Natl Cancer Inst 1974; 52:1571-7.
    • (1974) J Natl Cancer Inst , vol.52 , pp. 1571-1577
    • Zbar, B.1    Ribi, E.2    Meyer, T.3    Azuma, I.4    Rapp, H.J.5
  • 20
    • 0017202460 scopus 로고
    • Immunotherapy of cancer with cell wall skeleton of Myocabacterium bovis-Bacillus Calmette-Guerin: Experimental and clinical results
    • Yamamura Y, Azuma I, Taniyama T, Sugimura K, Hirao F, Tokuzen R, et al. Immunotherapy of cancer with cell wall skeleton of Myocabacterium bovis-Bacillus Calmette-Guerin: experimental and clinical results. Ann N Y Acad Sci 1976; 277:209-27.
    • (1976) Ann N Y Acad Sci , vol.277 , pp. 209-227
    • Yamamura, Y.1    Azuma, I.2    Taniyama, T.3    Sugimura, K.4    Hirao, F.5    Tokuzen, R.6
  • 21
    • 0018769475 scopus 로고
    • Nonspecific adjuvant immunotherapy of lung cancer with cell wall skeleton of Mycobacterium bovis Bacillus Calmette-Guerin
    • Yasumoto K, Manabe H, Yanagawa E, Nagano N, Ueda H, Hirota N, et al. Nonspecific adjuvant immunotherapy of lung cancer with cell wall skeleton of Mycobacterium bovis Bacillus Calmette-Guerin. Cancer Res 1979; 39:3262-7.
    • (1979) Cancer Res , vol.39 , pp. 3262-3267
    • Yasumoto, K.1    Manabe, H.2    Yanagawa, E.3    Nagano, N.4    Ueda, H.5    Hirota, N.6
  • 22
    • 0004627659 scopus 로고    scopus 로고
    • Immunofriendly use of BCG-cell wall skeleton remarkably improves the survival rate of various cancer patients
    • Hayashi A, Doi O, Azuma I, Toyoshima K. Immunofriendly use of BCG-cell wall skeleton remarkably improves the survival rate of various cancer patients. Proc Jpn Acad Ser B 1998; 74:50-5.
    • (1998) Proc Jpn Acad Ser B , vol.74 , pp. 50-55
    • Hayashi, A.1    Doi, O.2    Azuma, I.3    Toyoshima, K.4
  • 23
    • 44449120076 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 2 by a novel preparation of cell wall skeleton from Mycobacterium bovis BCG Tokyo (SMP-105) sufficiently enhances immune responses against tumors
    • Murata M. Activation of Toll-like receptor 2 by a novel preparation of cell wall skeleton from Mycobacterium bovis BCG Tokyo (SMP-105) sufficiently enhances immune responses against tumors. Cancer Sci 2008; 99:1435-40.
    • (2008) Cancer Sci , vol.99 , pp. 1435-1440
    • Murata, M.1
  • 24
    • 33846213509 scopus 로고    scopus 로고
    • Enhancement of immunologic tumor regression by intratumoral administration of dendritic cells in combination with cryoablative tumor pretreatment and Bacillus Calmette-Guerin cell wall skeleton stimulation
    • Udagawa M, Kudo-Saito C, Hasegawa G, Yano K, Yamamoto A, Yaguchi M, et al. Enhancement of immunologic tumor regression by intratumoral administration of dendritic cells in combination with cryoablative tumor pretreatment and Bacillus Calmette-Guerin cell wall skeleton stimulation. Clin Cancer Res 2006; 12:7465-75.
    • (2006) Clin Cancer Res , vol.12 , pp. 7465-7475
    • Udagawa, M.1    Kudo-Saito, C.2    Hasegawa, G.3    Yano, K.4    Yamamoto, A.5    Yaguchi, M.6
  • 25
    • 4344712684 scopus 로고    scopus 로고
    • Methods for monitoring autophagy
    • Mizushima N. Methods for monitoring autophagy. Int J Biochem Cell Biol 2004; 36:2491-502.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2491-2502
    • Mizushima, N.1
  • 27
    • 8044257699 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
    • Blommaart EF, Krause U, Schellens JP, Vreeling-Sindelarova H, Meijer AJ. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur J Biochem 1997; 243:240-6.
    • (1997) Eur J Biochem , vol.243 , pp. 240-246
    • Blommaart, E.F.1    Krause, U.2    Schellens, J.P.3    Vreeling-Sindelarova, H.4    Meijer, A.J.5
  • 29
    • 33745845126 scopus 로고    scopus 로고
    • Autophagy contributes to caspase-independent macrophage cell death
    • Xu Y, Kim SO, Li Y, Han J. Autophagy contributes to caspase-independent macrophage cell death. J Biol Chem 2006; 281:19179-87.
    • (2006) J Biol Chem , vol.281 , pp. 19179-19187
    • Xu, Y.1    Kim, S.O.2    Li, Y.3    Han, J.4
  • 30
    • 38349043984 scopus 로고    scopus 로고
    • Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species
    • Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB. Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci 2007; 120:4155-66.
    • (2007) J Cell Sci , vol.120 , pp. 4155-4166
    • Chen, Y.1    McMillan-Ward, E.2    Kong, J.3    Israels, S.J.4    Gibson, S.B.5
  • 31
    • 0028017694 scopus 로고
    • Diphenyleneiodonium inhibits reduction of iron-sulfur clusters in the mitochondrial NADH-ubiquinone oxidoreductase (Complex I)
    • Majander A, Finel M, Wikstrom M. Diphenyleneiodonium inhibits reduction of iron-sulfur clusters in the mitochondrial NADH-ubiquinone oxidoreductase (Complex I). J Biol Chem 1994; 269:21037-42.
    • (1994) J Biol Chem , vol.269 , pp. 21037-21042
    • Majander, A.1    Finel, M.2    Wikstrom, M.3
  • 32
    • 62449110463 scopus 로고    scopus 로고
    • Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
    • Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS, Iwasaki A. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc Natl Acad Sci USA 2009; 106:2770-5.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2770-2775
    • Tal, M.C.1    Sasai, M.2    Lee, H.K.3    Yordy, B.4    Shadel, G.S.5    Iwasaki, A.6
  • 33
    • 41449084234 scopus 로고    scopus 로고
    • Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death
    • Pyo JO, Nah J, Kim HJ, Lee HJ, Heo J, Lee H, Jung YK. Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death. Autophagy 2008; 4:315-21.
    • (2008) Autophagy , vol.4 , pp. 315-321
    • Pyo, J.O.1    Nah, J.2    Kim, H.J.3    Lee, H.J.4    Heo, J.5    Lee, H.6    Jung, Y.K.7
  • 34
    • 44949237240 scopus 로고    scopus 로고
    • JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
    • Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30:678-88.
    • (2008) Mol Cell , vol.30 , pp. 678-688
    • Wei, Y.1    Pattingre, S.2    Sinha, S.3    Bassik, M.4    Levine, B.5
  • 35
    • 0034443265 scopus 로고    scopus 로고
    • Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: Involvement of toll-like receptors
    • Tsuji S, Matsumoto M, Takeuchi O, Akira S, Azuma I, Hayashi A, et al. Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: involvement of toll-like receptors. Infect Immun 2000; 68:6883-90.
    • (2000) Infect Immun , vol.68 , pp. 6883-6890
    • Tsuji, S.1    Matsumoto, M.2    Takeuchi, O.3    Akira, S.4    Azuma, I.5    Hayashi, A.6
  • 36
    • 0043267978 scopus 로고    scopus 로고
    • Simultaneous blocking of human Toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis bacillus Calmette-Guerin peptidoglycan
    • Uehori J, Matsumoto M, Tsuji S, Akazawa T, Takeuchi O, Akira S, et al. Simultaneous blocking of human Toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis bacillus Calmette-Guerin peptidoglycan. Infect Immun 2003; 71:4238-49.
    • (2003) Infect Immun , vol.71 , pp. 4238-4249
    • Uehori, J.1    Matsumoto, M.2    Tsuji, S.3    Akazawa, T.4    Takeuchi, O.5    Akira, S.6
  • 37
    • 34248192226 scopus 로고    scopus 로고
    • Harnessing the immune system to treat cancer
    • Bhardwaj N. Harnessing the immune system to treat cancer. J Clin Invest 2007; 117:1130-6.
    • (2007) J Clin Invest , vol.117 , pp. 1130-1136
    • Bhardwaj, N.1
  • 38
    • 41149169239 scopus 로고    scopus 로고
    • Liu CL, Chen S, Dietrich D, Hu BR. Change in autophagy after traumatic brain injury. J Cereb Blood Flow Metab 2008; 28:674-83.
    • Liu CL, Chen S, Dietrich D, Hu BR. Change in autophagy after traumatic brain injury. J Cereb Blood Flow Metab 2008; 28:674-83.
  • 39
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's Achilles' heel
    • Kroemer G, Pouyssegur J. Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 2008; 13:472-82.
    • (2008) Cancer Cell , vol.13 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 40
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: Their role in cell survival and cell death
    • Codogno P, Meijer AJ. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 2005; 2:1509-18.
    • (2005) Cell Death Differ , vol.2 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 41
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • Kondo Y, Kanzawa T, Sawaya R, Kondo S. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 2005; 5:726-34.
    • (2005) Nat Rev Cancer , vol.5 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4
  • 43
    • 34548188741 scopus 로고    scopus 로고
    • Selfeating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Selfeating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007; 8:741-52.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 44
    • 33947417275 scopus 로고    scopus 로고
    • Crosstalk between Bak/Bax and mTOR signaling regulates radiationinduced autophagy
    • Moretti L, Attia A, Kim KW, Lu B. Crosstalk between Bak/Bax and mTOR signaling regulates radiationinduced autophagy. Autophagy 2007; 3:142-4.
    • (2007) Autophagy , vol.3 , pp. 142-144
    • Moretti, L.1    Attia, A.2    Kim, K.W.3    Lu, B.4
  • 46
    • 33846018602 scopus 로고    scopus 로고
    • Cell death by necrosis: Towards a molecular definition
    • Golstein P, Kroemer G. Cell death by necrosis: towards a molecular definition. Trends Biochem Sci 2007; 32:37-43.
    • (2007) Trends Biochem Sci , vol.32 , pp. 37-43
    • Golstein, P.1    Kroemer, G.2
  • 48
  • 49
    • 37349067228 scopus 로고    scopus 로고
    • Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
    • Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB. Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death Differ 2008; 15:171-82.
    • (2008) Cell Death Differ , vol.15 , pp. 171-182
    • Chen, Y.1    McMillan-Ward, E.2    Kong, J.3    Israels, S.J.4    Gibson, S.B.5
  • 50
    • 33845996199 scopus 로고    scopus 로고
    • Link between mitochondria and NADPH oxidase 1 isozyme for the sustained production of reactive oxygen species and cell death
    • Lee SB, Bae IH, Bae YS, Um HD. Link between mitochondria and NADPH oxidase 1 isozyme for the sustained production of reactive oxygen species and cell death. J Biol Chem 2006; 281:36228-35.
    • (2006) J Biol Chem , vol.281 , pp. 36228-36235
    • Lee, S.B.1    Bae, I.H.2    Bae, Y.S.3    Um, H.D.4
  • 53
    • 60149098492 scopus 로고    scopus 로고
    • 2-terminal kinasemediated Beclin 1 expression during anticancer agentsinduced autophagy in cancer cells
    • 2-terminal kinasemediated Beclin 1 expression during anticancer agentsinduced autophagy in cancer cells. Oncogene 2009; 28:886-98.
    • (2009) Oncogene , vol.28 , pp. 886-898
    • Li, D.D.1    Wang, L.L.2    Deng, R.3    Tang, J.4    Shen, Y.5    Guo, J.F.6
  • 54
  • 55
    • 10044265209 scopus 로고    scopus 로고
    • JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
    • Ventura JJ, Cogswell P, Flavell RA, Baldwin AS Jr, Davis RJ. JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev 2004; 18:2905-15.
    • (2004) Genes Dev , vol.18 , pp. 2905-2915
    • Ventura, J.J.1    Cogswell, P.2    Flavell, R.A.3    Baldwin Jr, A.S.4    Davis, R.J.5
  • 57
    • 14844327760 scopus 로고    scopus 로고
    • Reactive oxygen species promote TNFalphainduced death and sustained JNK activation by inhibiting MAP kinase phosphatases
    • Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M. Reactive oxygen species promote TNFalphainduced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 2005; 120:649-61.
    • (2005) Cell , vol.120 , pp. 649-661
    • Kamata, H.1    Honda, S.2    Maeda, S.3    Chang, L.4    Hirata, H.5    Karin, M.6
  • 58
  • 59
    • 62449275805 scopus 로고    scopus 로고
    • Innate immune therapy with a Bacillus Calmette-Guerin cell wall skeleton after radical surgery for non-small cell lung cancer: A case-control study
    • Kodama K, Higashiyama M, Takami K, Oda K, Okami J, Maeda J, et al. Innate immune therapy with a Bacillus Calmette-Guerin cell wall skeleton after radical surgery for non-small cell lung cancer: A case-control study. Surg Today 2009; 39:194-200.
    • (2009) Surg Today , vol.39 , pp. 194-200
    • Kodama, K.1    Higashiyama, M.2    Takami, K.3    Oda, K.4    Okami, J.5    Maeda, J.6
  • 61
    • 0015956704 scopus 로고
    • Biologically active components from mycobacterial cell walls I. Isolation and composition of cell wall skeleton and component P3
    • Azuma I, Ribi EE, Meyer TJ. Biologically active components from mycobacterial cell walls I. Isolation and composition of cell wall skeleton and component P3. J Natl Cancer Inst 1974; 52:95-101.
    • (1974) J Natl Cancer Inst , vol.52 , pp. 95-101
    • Azuma, I.1    Ribi, E.E.2    Meyer, T.J.3
  • 62
    • 42449117212 scopus 로고    scopus 로고
    • The chemopreventive agent curcumin is a potent radio-sensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway
    • Javvadi P, Segan AT, Tuttle SW, Koumenis C. The chemopreventive agent curcumin is a potent radio-sensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway. Mol Pharmacol 2008; 73:1491-501.
    • (2008) Mol Pharmacol , vol.73 , pp. 1491-1501
    • Javvadi, P.1    Segan, A.T.2    Tuttle, S.W.3    Koumenis, C.4
  • 63
    • 65449128448 scopus 로고    scopus 로고
    • NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression
    • Yang CS, Shin DM, Kim KH, Lee ZW, Lee CH, Park SG, et al. NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression. J Immunol 2009; 182:3696-705.
    • (2009) J Immunol , vol.182 , pp. 3696-3705
    • Yang, C.S.1    Shin, D.M.2    Kim, K.H.3    Lee, Z.W.4    Lee, C.H.5    Park, S.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.