Enhancing chemosensitivity in ABCB1- and ABCG2-overexpressing cells and cancer stem-like cells by an Aurora kinase inhibitor CCT129202

Molecular Pharmaceutics

Volumn 9, Issue 7, 2012, Pages 1971-1982

  Cheng, Chao ^a   Liu, Zhen Guo ^a   Zhang, Hui ^b   Xie, Jing Dun ^b   Chen, Xing Gui ^b   Zhao, Xiao Qin ^b   Wang, Fang ^b   Liang, Yong Ju ^b   Chen, Li Kun ^b   Singh, Satyakam ^c   Chen, Jun Jiang ^c   Talele, Tanaji T ^c   Chen, Zhe Sheng ^c   Zhong, Fo Tian ^a   Fu, Li Wu ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c ST JOHN'S UNIVERSITY   (United States)

Author keywords

ATP binding cassette transporters; aurora kinase inhibitor; cancer stem like cells; CCT129202; multidrug resistance

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; CCT 129202; DOXORUBICIN; FUMITREMORGIN C; HOE 33342; IMIDAZOPYRIDINE DERIVATIVE; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; RHODAMINE 123; TOPOTECAN; UNCLASSIFIED DRUG; VERAPAMIL; VERLUKAST; VINCRISTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER STEM CELL; CELL SURVIVAL; CHEMOSENSITIVITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG POTENTIATION; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYDROPHOBICITY; MALE; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; AURORA KINASES; CELL LINE; CELL LINE, TUMOR; DRUG INTERACTIONS; DRUG RESISTANCE, MULTIPLE; HEK293 CELLS; HL-60 CELLS; HUMANS; IMIDAZOLES; MALE; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; P-GLYCOPROTEIN; PROTEIN KINASE INHIBITORS; PYRIDINES;

EID: 84863307663     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp2006714     Document Type: Article

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