메뉴 건너뛰기




Volumn 27, Issue 5, 2012, Pages 1669-1673

3,3′-Diindolylmethane suppresses growth of human esophageal squamous cancer cells by G1 cell cycle arrest

Author keywords

3,3 diindolylmethane; Apoptosis; G1 arrest; Human esophageal squamous carcinoma cells

Indexed keywords

3,3' DIINDOLYLMETHANE; CASPASE 9; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN E; CYCLIN E2; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P15; PROTEIN P27; UNCLASSIFIED DRUG; 3,3'-DIINDOLYLMETHANE; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; CELL CYCLE PROTEIN; INDOLE DERIVATIVE;

EID: 84863281650     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1662     Document Type: Article
Times cited : (28)

References (38)
  • 2
    • 0036151675 scopus 로고    scopus 로고
    • Outcome of esophageal adenocarcinoma detected during endoscopic biopsy surveillance for Barrett's esophagus
    • DOI 10.1007/s00464-001-8161-3
    • Incarbone R, Bonavina L, Saino G, Bona D and Peracchia A: Outcome of esophageal adenocarcinoma detected during endoscopic biopsy surveillance for Barrett's esophagus. Surg Endosc 16: 263-266, 2002. (Pubitemid 34112973)
    • (2002) Surgical Endoscopy , vol.16 , Issue.2 , pp. 263-266
    • Incarbone, R.1    Bonavina, L.2    Saino, G.3    Bona, D.4    Peracchia, A.5
  • 3
    • 79957441529 scopus 로고    scopus 로고
    • Curative treatment of oesophageal carcinoma: Current options and future developments
    • Wolf MC, Stahl M, Krause BJ, et al: Curative treatment of oesophageal carcinoma: current options and future developments. Radiat Oncol 6: 55, 2011.
    • (2011) Radiat Oncol , vol.6 , pp. 55
    • Wolf, M.C.1    Stahl, M.2    Krause, B.J.3
  • 4
    • 78649788897 scopus 로고    scopus 로고
    • Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome
    • Kim SM, Park YY, Park ES, et al: Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome. PLoS One 5: e15074, 2010.
    • (2010) PLoS One , vol.5
    • Kim, S.M.1    Park, Y.Y.2    Park, E.S.3
  • 6
    • 27844456998 scopus 로고    scopus 로고
    • Osophagektomie als chirurgisches therapieprinzip beim plattenepithelkarzinom des osophagus
    • DOI 10.1007/s00104-005-1096-9
    • Siewert JR, Feith M and Stein HJ: Esophagectomy as therapeutic principle for squamous cell esophageal cancer. Chirurg 76: 1033-1043, 2005 (In German). (Pubitemid 41639857)
    • (2005) Chirurg , vol.76 , Issue.11 , pp. 1033-1043
    • Siewert, J.R.1    Feith, M.2    Stein, H.J.3
  • 7
    • 0034858057 scopus 로고    scopus 로고
    • Histologic tumor type is an independent prognostic parameter in esophageal cancer: Lessons from more than 1,000 consecutive resections at a single center in the Western world
    • DOI 10.1097/00000658-200109000-00010
    • Siewert JR, Stein HJ, Feith M, Bruecher BL, Bartels H and Fink U: Histologic tumor type is an independent prognostic parameter in esophageal cancer: lessons from more than 1,000 consecutive resections at a single center in the Western world. Ann Surg 234: 360-369, 2001. (Pubitemid 32847073)
    • (2001) Annals of Surgery , vol.234 , Issue.3 , pp. 360-369
    • Siewert, J.R.1    Stein, H.J.2    Feith, M.3    Bruecher, B.L.D.M.4    Bartels, H.5    Fink, U.6
  • 11
    • 33845964968 scopus 로고    scopus 로고
    • Activation of caspase-8 contributes to 3,3′-diindolylmethane- induced apoptosis in colon cancer cells
    • Kim EJ, Park SY, Shin HK, Kwon DY, Surh YJ and Park JH: Activation of caspase-8 contributes to 3,3′-diindolylmethane-induced apoptosis in colon cancer cells. J Nutr 137: 31-36, 2007.
    • (2007) J Nutr , vol.137 , pp. 31-36
    • Kim, E.J.1    Park, S.Y.2    Shin, H.K.3    Kwon, D.Y.4    Surh, Y.J.5    Park, J.H.6
  • 12
    • 0018137952 scopus 로고
    • Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles
    • Wattenberg LW and Loub WD: Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles. Cancer Res 38: 1410-1413, 1978. (Pubitemid 8323347)
    • (1978) Cancer Research , vol.38 , Issue.5 , pp. 1410-1413
    • Wattenberg, L.W.1    Loub, W.D.2
  • 13
    • 0031715037 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
    • DOI 10.1093/carcin/19.9.1631
    • Chen I, McDougal A, Wang F and Safe S: Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis 19: 1631-1639, 1998. (Pubitemid 28441867)
    • (1998) Carcinogenesis , vol.19 , Issue.9 , pp. 1631-1639
    • Chen, I.1    McDougal, A.2    Wang, F.3    Safe, S.4
  • 14
    • 49849102783 scopus 로고    scopus 로고
    • Apoptosis-inducing effect of erlotinib is potentiated by 3,3′-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer
    • Ali S, Banerjee S, Ahmad A, El-Rayes BF, Philip PA and Sarkar FH: Apoptosis-inducing effect of erlotinib is potentiated by 3,3′- diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer. Mol Cancer Ther 7: 1708-1719, 2008.
    • (2008) Mol Cancer Ther , vol.7 , pp. 1708-1719
    • Ali, S.1    Banerjee, S.2    Ahmad, A.3    El-Rayes, B.F.4    Philip, P.A.5    Sarkar, F.H.6
  • 15
    • 60849123921 scopus 로고    scopus 로고
    • Cell cycle-dependent effects of 3,3′-diindolylmethane on proliferation and apoptosis of prostate cancer cells
    • Chinnakannu K, Chen D, Li Y, et al: Cell cycle-dependent effects of 3,3′-diindolylmethane on proliferation and apoptosis of prostate cancer cells. J Cell Physiol 219: 94-99, 2009.
    • (2009) J Cell Physiol , vol.219 , pp. 94-99
    • Chinnakannu, K.1    Chen, D.2    Li, Y.3
  • 16
    • 33750541268 scopus 로고    scopus 로고
    • Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells
    • DOI 10.1158/0008-5472.CAN-06-2011
    • Bhuiyan MM, Li Y, Banerjee S, et al: Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells. Cancer Res 66: 10064-10072, 2006. (Pubitemid 44672060)
    • (2006) Cancer Research , vol.66 , Issue.20 , pp. 10064-10072
    • Bhuiyan, M.M.R.1    Li, Y.2    Banerjee, S.3    Ahmed, F.4    Wang, Z.5    Ali, S.6    Sarkar, F.H.7
  • 17
    • 40949131914 scopus 로고    scopus 로고
    • Mammalian target of rapamycin repression by 3,3′-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC3 cells
    • DOI 10.1158/0008-5472.CAN-07-3241
    • Kong D, Banerjee S, Huang W, et al: Mammalian target of rapamycin repression by 3,3′-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC3 cells. Cancer Res 68: 1927-1934, 2008. (Pubitemid 351416579)
    • (2008) Cancer Research , vol.68 , Issue.6 , pp. 1927-1934
    • Kong, D.1    Banerjee, S.2    Huang, W.3    Li, Y.4    Wang, Z.5    Kim, H.-R.C.6    Sarkar, F.H.7
  • 18
    • 17444430817 scopus 로고    scopus 로고
    • Selective growth regulatory and pro-apoptotic effects of DIM is mediated by Akt and NF-kappaB pathways in prostate cancer cells
    • Li Y, Chinni SR and Sarkar FH: Selective growth regulatory and pro-apoptotic effects of DIM is mediated by AKT and NF-kappaB pathways in prostate cancer cells. Front Biosci 10: 236-243, 2005. (Pubitemid 40543031)
    • (2005) Frontiers in Bioscience , vol.10 , Issue.1 , pp. 236-243
    • Li, Y.1    Chinni, S.R.2    Sarkar, F.H.3
  • 19
    • 4544358789 scopus 로고    scopus 로고
    • Therapeutic activity of 3,3′-diindolylmethane on prostate cancer in an in vivo model
    • DOI 10.1002/pros.20092
    • Nachshon-Kedmi M, Fares FA and Yannai S: Therapeutic activity of 3,3′-diindolylmethane on prostate cancer in an in vivo model. Prostate 61: 153-160, 2004. (Pubitemid 39244702)
    • (2004) Prostate , vol.61 , Issue.2 , pp. 153-160
    • Nachshon-Kedmi, M.1    Fares, F.A.2    Yannai, S.3
  • 20
    • 11244282153 scopus 로고    scopus 로고
    • Inhibition of nuclear translocation of nuclear factor-{kappa}B contributes to 3,3′-diindolylmethane-induced apoptosis in breast cancer cells
    • Rahman KW and Sarkar FH: Inhibition of nuclear translocation of nuclear factor-{kappa}B contributes to 3,3′-diindolylmethane-induced apoptosis in breast cancer cells. Cancer Res 65: 364-371, 2005.
    • (2005) Cancer Res , vol.65 , pp. 364-371
    • Rahman, K.W.1    Sarkar, F.H.2
  • 21
    • 33645294370 scopus 로고    scopus 로고
    • 3,3′-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5
    • Abdelrahim M, Newman K, Vanderlaag K, Samudio I and Safe S: 3,3′-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5. Carcinogenesis 27: 717-728, 2006.
    • (2006) Carcinogenesis , vol.27 , pp. 717-728
    • Abdelrahim, M.1    Newman, K.2    Vanderlaag, K.3    Samudio, I.4    Safe, S.5
  • 23
    • 49549124992 scopus 로고    scopus 로고
    • Chemoprevention of pancreatic cancer: Characterization of Par-4 and its modulation by 3,3-diindolylmethane (DIM)
    • Azmi AS, Ahmad A, Banerjee S, Rangnekar VM, Mohammad RM and Sarkar FH: Chemoprevention of pancreatic cancer: characterization of Par-4 and its modulation by 3,3-diindolylmethane (DIM). Pharm Res 25: 2117-2124, 2008.
    • (2008) Pharm Res , vol.25 , pp. 2117-2124
    • Azmi, A.S.1    Ahmad, A.2    Banerjee, S.3    Rangnekar, V.M.4    Mohammad, R.M.5    Sarkar, F.H.6
  • 24
    • 80054824456 scopus 로고    scopus 로고
    • Deciphering the role of paclitaxel in the SKGT4 human esophageal adenocarcinoma cell line
    • Kim SJ, Chung MJ, Kim JS, et al: Deciphering the role of paclitaxel in the SKGT4 human esophageal adenocarcinoma cell line. Int J Oncol 39: 1587-1591, 2011.
    • (2011) Int J Oncol , vol.39 , pp. 1587-1591
    • Kim, S.J.1    Chung, M.J.2    Kim, J.S.3
  • 26
    • 67650496175 scopus 로고    scopus 로고
    • 3,3′-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer
    • Banerjee S, Wang Z, Kong D and Sarkar FH: 3,3′-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer. Cancer Res 69: 5592-5600, 2009.
    • (2009) Cancer Res , vol.69 , pp. 5592-5600
    • Banerjee, S.1    Wang, Z.2    Kong, D.3    Sarkar, F.H.4
  • 27
    • 0344844481 scopus 로고    scopus 로고
    • Indole-3-Carbinol Induces a G1 Cell Cycle Arrest and Inhibits Prostate-Specific Antigen Production in Human LNCaP Prostate Carcinoma Cells
    • DOI 10.1002/cncr.11844
    • Zhang J, Hsu BAJ, Kinseth BAM, Bjeldanes LF and Firestone GL: Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells. Cancer 98: 2511-2520, 2003. (Pubitemid 37466668)
    • (2003) Cancer , vol.98 , Issue.11 , pp. 2511-2520
    • Zhang, J.1    Hsu, J.C.2    Kinseth, M.A.3    Bjeldanes, L.F.4    Firestone, G.L.5
  • 28
    • 25444449603 scopus 로고    scopus 로고
    • Molecular targets and anticancer potential of indole-3-carbinol and its derivatives
    • Aggarwal BB and Ichikawa H: Molecular targets and anticancer potential of indole-3-carbinol and its derivatives. Cell Cycle 4: 1201-1215, 2005. (Pubitemid 41365390)
    • (2005) Cell Cycle , vol.4 , Issue.9 , pp. 1201-1215
    • Aggarwal, B.B.1    Ichikawa, H.2
  • 29
    • 34248178375 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the NF-kappaB downstream target genes MMP-9 and uPA that regulated bioavailability of VEGF in prostate cancer
    • DOI 10.1158/0008-5472.CAN-06-4277
    • Kong D, Li Y, Wang Z, Banerjee S and Sarkar FH: Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-kappaB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer. Cancer Res 67: 3310-3319, 2007. (Pubitemid 46724870)
    • (2007) Cancer Research , vol.67 , Issue.7 , pp. 3310-3319
    • Kong, D.1    Li, Y.2    Wang, Z.3    Banerjee, S.4    Sarkar, F.H.5
  • 30
    • 34547135737 scopus 로고    scopus 로고
    • Regulation of FOXO3a/beta-catenin/GSK-3beta signaling by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells
    • DOI 10.1074/jbc.M701978200
    • Li Y, Wang Z, Kong D, et al: Regulation of FOXO3a/beta-catenin/GSK-3beta signaling by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells. J Biol Chem 282: 21542-21550, 2007. (Pubitemid 47099972)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.29 , pp. 21542-21550
    • Li, Y.1    Wang, Z.2    Kong, D.3    Murthy, S.4    Dou, Q.P.5    Sheng, S.6    Veer, R.G.P.7    Sarkar, F.H.8
  • 31
    • 67649464189 scopus 로고    scopus 로고
    • 3,3′-Diindo- Lylmethane induces a G(1) arrest in human prostate cancer cells irrespective of androgen receptor and p53 status
    • Vivar OI, Lin CL, Firestone GL and Bjeldanes LF: 3,3′-Diindo- lylmethane induces a G(1) arrest in human prostate cancer cells irrespective of androgen receptor and p53 status. Biochem Pharmacol 78: 469-476, 2009.
    • (2009) Biochem Pharmacol , vol.78 , pp. 469-476
    • Vivar, O.I.1    Lin, C.L.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 32
    • 67649641442 scopus 로고    scopus 로고
    • Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3′-diindolylmethane in HT-29 human colon cancer cells
    • Choi HJ, Lim do Y and Park JH: Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3′-diindolylmethane in HT-29 human colon cancer cells. BMC Gastroenterol 9: 39, 2009.
    • (2009) BMC Gastroenterol , vol.9 , pp. 39
    • Choi, H.J.1    Lim Do, Y.2    Park, J.H.3
  • 33
    • 78651430467 scopus 로고    scopus 로고
    • 3,3′-Diindo- Lylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model
    • Cho HJ, Park SY, Kim EJ, Kim JK and Park JH: 3,3′-Diindo- lylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model. Mol Carcinog 50: 100-112, 2011.
    • (2011) Mol Carcinog , vol.50 , pp. 100-112
    • Cho, H.J.1    Park, S.Y.2    Kim, E.J.3    Kim, J.K.4    Park, J.H.5
  • 34
    • 0035984590 scopus 로고    scopus 로고
    • 3,3′-Diindo- Lylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression
    • Hong C, Kim HA, Firestone GL and Bjeldanes LF: 3,3′-Diindo- lylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression. Carcinogenesis 23: 1297-1305, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 1297-1305
    • Hong, C.1    Kim, H.A.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 35
    • 33644830944 scopus 로고    scopus 로고
    • Targeting the cell cycle: A new approach to cancer therapy
    • Schwartz GK and Shah MA: Targeting the cell cycle: a new approach to cancer therapy. J Clin Oncol 23: 9408-9421, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 9408-9421
    • Schwartz, G.K.1    Shah, M.A.2
  • 38
    • 16444368121 scopus 로고    scopus 로고
    • Cell cycle regulation and its aberrations in human lung carcinoma
    • Dobashi Y: Cell cycle regulation and its aberrations in human lung carcinoma. Pathol Int 55: 95-105, 2005.
    • (2005) Pathol Int , vol.55 , pp. 95-105
    • Dobashi, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.