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Volumn 219, Issue 1, 2009, Pages 94-99

Cell cycle-dependent effects of 3,3'-diindolylmethane on proliferation and apoptosis of prostate cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLEMETHANOL; 3,3 DIINDOLYLMETHANE; ANDROGEN; ANDROGEN RECEPTOR; CYCLIN DEPENDENT KINASE INHIBITOR 1B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEASOME; PROTEIN BCL 2; UNCLASSIFIED DRUG; CDKN1B PROTEIN, HUMAN; DIINDOLYLMETHANE; INDOLE DERIVATIVE; ISOLEUCINE; SIGNAL PEPTIDE;

EID: 60849123921     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21650     Document Type: Article
Times cited : (34)

References (39)
  • 1
    • 2442672870 scopus 로고    scopus 로고
    • Physiological modeling of formulated and crystalline 3,3'-diindolylmethane pharmacokinetics following oral administration in mice
    • Anderton MJ, Manson MM, Verschoyle R, Gescher A, Steward WP, Williams ML, Mager DE. 2004. Physiological modeling of formulated and crystalline 3,3'-diindolylmethane pharmacokinetics following oral administration in mice. Drug Metab Dispos 32:632-638.
    • (2004) Drug Metab Dispos , vol.32 , pp. 632-638
    • Anderton, M.J.1    Manson, M.M.2    Verschoyle, R.3    Gescher, A.4    Steward, W.P.5    Williams, M.L.6    Mager, D.E.7
  • 2
    • 65949115654 scopus 로고    scopus 로고
    • Balk SP, Knudsen KE. 2008. AR, the cell cycle, and prostate cancer. Nucl Recept Signal 6:e001 [Epub]. Bhuiyan MM, Li Y, Banerjee S, Ahmed F, Wang Z, Ali S, Sarkar FH. 2006. Down-regulation of androgen receptor by 3,3'- diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells. Cancer Res 66:10064-10072.
    • Balk SP, Knudsen KE. 2008. AR, the cell cycle, and prostate cancer. Nucl Recept Signal 6:e001 [Epub]. Bhuiyan MM, Li Y, Banerjee S, Ahmed F, Wang Z, Ali S, Sarkar FH. 2006. Down-regulation of androgen receptor by 3,3'- diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells. Cancer Res 66:10064-10072.
  • 3
    • 33847784791 scopus 로고    scopus 로고
    • Multiple levels of cyclin specificity in cell-cycle control
    • Bloom J, Cross FR. 2007. Multiple levels of cyclin specificity in cell-cycle control. Nat Rev Mol Cell Biol 8:149-160.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 149-160
    • Bloom, J.1    Cross, F.R.2
  • 4
    • 31544436372 scopus 로고    scopus 로고
    • Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells
    • Brew CT, Aronchik I, Hsu JC, Sheen JH, Dickson RB, Bjeldanes LF, Firestone GL. 2006. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells. Int J Cancer 118:857-868.
    • (2006) Int J Cancer , vol.118 , pp. 857-868
    • Brew, C.T.1    Aronchik, I.2    Hsu, J.C.3    Sheen, J.H.4    Dickson, R.B.5    Bjeldanes, L.F.6    Firestone, G.L.7
  • 5
    • 0036196320 scopus 로고    scopus 로고
    • NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer
    • Chen CD, Sawyers CL. 2002. NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer. Mol Cell Biol 22:2862-2870.
    • (2002) Mol Cell Biol , vol.22 , pp. 2862-2870
    • Chen, C.D.1    Sawyers, C.L.2
  • 7
    • 50949098870 scopus 로고    scopus 로고
    • Proteasome inhibitors enhance TRAIL- induced apoptosis through the intronic regulation of DR5: Involvement of NF-kappaB and reactive oxygen species-mediated p53 activation
    • Chen JJ, Chou CW, Chang YF, Chen CC. 2008. Proteasome inhibitors enhance TRAIL- induced apoptosis through the intronic regulation of DR5: Involvement of NF-kappaB and reactive oxygen species-mediated p53 activation. J Immunol 180:8030-8039.
    • (2008) J Immunol , vol.180 , pp. 8030-8039
    • Chen, J.J.1    Chou, C.W.2    Chang, Y.F.3    Chen, C.C.4
  • 8
    • 1842640465 scopus 로고    scopus 로고
    • Induction of G1 arrest and apoptosis in human jurkat T cells by pentagalloylglucose through inhibiting proteasome activity and elevating p27Kip1, p21Cip1/WAF1, and Bax proteins
    • Chen WJ, Lin JK. 2004. Induction of G1 arrest and apoptosis in human jurkat T cells by pentagalloylglucose through inhibiting proteasome activity and elevating p27Kip1, p21Cip1/WAF1, and Bax proteins. J Biol Chem 279:13496-13505.
    • (2004) J Biol Chem , vol.279 , pp. 13496-13505
    • Chen, W.J.1    Lin, J.K.2
  • 9
    • 0036554871 scopus 로고    scopus 로고
    • Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells
    • Chinni SR, Sarkar FH. 2002. Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells. Clin Cancer Res 8:1228-1236.
    • (2002) Clin Cancer Res , vol.8 , pp. 1228-1236
    • Chinni, S.R.1    Sarkar, F.H.2
  • 10
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
    • Chu IM, Hengst L, Slingerland JM. 2008. The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 8:253-267.
    • (2008) Nat Rev Cancer , vol.8 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 11
    • 0037731923 scopus 로고    scopus 로고
    • Synchronized prostate cancer cells for studying androgen regulated events in cell cycle progression from G1 into S phase
    • Cifuentes E, Croxen R, Menon M, Barrack ER, Reddy GP. 2003. Synchronized prostate cancer cells for studying androgen regulated events in cell cycle progression from G1 into S phase. J Cell Physiol 195:337-345.
    • (2003) J Cell Physiol , vol.195 , pp. 337-345
    • Cifuentes, E.1    Croxen, R.2    Menon, M.3    Barrack, E.R.4    Reddy, G.P.5
  • 13
    • 34249781706 scopus 로고    scopus 로고
    • Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer
    • Daniel KG, Chen D, Yan B, Dou QP. 2007. Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer. Front Biosci 12:135-144.
    • (2007) Front Biosci , vol.12 , pp. 135-144
    • Daniel, K.G.1    Chen, D.2    Yan, B.3    Dou, Q.P.4
  • 14
    • 52949120373 scopus 로고    scopus 로고
    • Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells
    • Domingo-Domenech J, Pippa R, Tapia M, Gascon P, Bachs O, Bosch M. 2008. Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. Breast Cancer Res Treat 112:53-62.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 53-62
    • Domingo-Domenech, J.1    Pippa, R.2    Tapia, M.3    Gascon, P.4    Bachs, O.5    Bosch, M.6
  • 16
    • 2342558431 scopus 로고    scopus 로고
    • Androgen receptor in prostate cancer
    • Heinlein CA, Chang C. 2004. Androgen receptor in prostate cancer. Endocr Rev 25:276-308.
    • (2004) Endocr Rev , vol.25 , pp. 276-308
    • Heinlein, C.A.1    Chang, C.2
  • 18
    • 34248178375 scopus 로고    scopus 로고
    • 3, 3'-diindolylmethane is mediated by NF-kappaB downstream target genes MMP-9 and uPA regulated bioavailability of VEGF in prostate cancer
    • 3, 3'-diindolylmethane is mediated by NF-kappaB downstream target genes MMP-9 and uPA regulated bioavailability of VEGF in prostate cancer. Cancer Res 67:3310-3319.
    • Cancer Res , vol.67 , pp. 3310-3319
  • 19
    • 20344407552 scopus 로고    scopus 로고
    • Requirement for NF-(kappa)B in interleukin-4-induced androgen receptor activation in prostate cancer cells
    • Lee SO, Lou W, Nadiminty N, Lin X, Gao AC. 2005. Requirement for NF-(kappa)B in interleukin-4-induced androgen receptor activation in prostate cancer cells. Prostate 64:160-167.
    • (2005) Prostate , vol.64 , pp. 160-167
    • Lee, S.O.1    Lou, W.2    Nadiminty, N.3    Lin, X.4    Gao, A.C.5
  • 20
    • 17444430817 scopus 로고    scopus 로고
    • Selective growth regulatory and pro-apoptotic effects of DIM is mediated by AKT and NF-kappaB pathways in prostate cancer cells
    • Li Y, Chinni SR, Sarkar FH. 2005. Selective growth regulatory and pro-apoptotic effects of DIM is mediated by AKT and NF-kappaB pathways in prostate cancer cells. Front Biosci 10:236-243.
    • (2005) Front Biosci , vol.10 , pp. 236-243
    • Li, Y.1    Chinni, S.R.2    Sarkar, F.H.3
  • 21
    • 0037384508 scopus 로고    scopus 로고
    • Gene expression profiles of I3C- and DIM-treated PC3 human prostate cancer cells determined by cDNA microarray analysis
    • Li Y, Li X, Sarkar FH. 2003. Gene expression profiles of I3C- and DIM-treated PC3 human prostate cancer cells determined by cDNA microarray analysis. J Nutr 133:1011-1019.
    • (2003) J Nutr , vol.133 , pp. 1011-1019
    • Li, Y.1    Li, X.2    Sarkar, F.H.3
  • 22
    • 34547135737 scopus 로고    scopus 로고
    • Regulation of FOXO3a/beta-catenin/GSK-3beta signaling by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells
    • Li Y, Wang Z, Kong D, Murthy S, Dou QP, Sheng S, Reddy GP, Sarkar FH. 2007. Regulation of FOXO3a/beta-catenin/GSK-3beta signaling by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells. J Biol Chem 282:21542-21550.
    • (2007) J Biol Chem , vol.282 , pp. 21542-21550
    • Li, Y.1    Wang, Z.2    Kong, D.3    Murthy, S.4    Dou, Q.P.5    Sheng, S.6    Reddy, G.P.7    Sarkar, F.H.8
  • 24
    • 6944231023 scopus 로고    scopus 로고
    • Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3'-diindolylmethane through the mitochondrial pathway
    • Nachshon-Kedmi M, Yannai S, Fares FA. 2004. Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3'-diindolylmethane through the mitochondrial pathway. Br J Cancer 91:1358-1363.
    • (2004) Br J Cancer , vol.91 , pp. 1358-1363
    • Nachshon-Kedmi, M.1    Yannai, S.2    Fares, F.A.3
  • 25
    • 0038402729 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3'- diindolylmethane induce apoptosis in human prostate cancer cells
    • Nachshon-Kedmi M, Yannai S, Haj A, Fares FA. 2003. Indole-3-carbinol and 3,3'- diindolylmethane induce apoptosis in human prostate cancer cells. Food Chem Toxicol 41:745-752.
    • (2003) Food Chem Toxicol , vol.41 , pp. 745-752
    • Nachshon-Kedmi, M.1    Yannai, S.2    Haj, A.3    Fares, F.A.4
  • 26
    • 0035918278 scopus 로고    scopus 로고
    • Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo
    • Nam S, Smith DM, Dou QP. 2001. Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo. J Biol Chem 276:13322-13330.
    • (2001) J Biol Chem , vol.276 , pp. 13322-13330
    • Nam, S.1    Smith, D.M.2    Dou, Q.P.3
  • 27
    • 0036678959 scopus 로고    scopus 로고
    • Role and function of the 26S proteasome in proliferation and apoptosis
    • Naujokat C, Hoffmann S. 2002. Role and function of the 26S proteasome in proliferation and apoptosis. Lab Invest 82:965-980.
    • (2002) Lab Invest , vol.82 , pp. 965-980
    • Naujokat, C.1    Hoffmann, S.2
  • 30
    • 41549133200 scopus 로고    scopus 로고
    • Proteasome inhibitors in cancer therapy: Lessons from the first decade
    • Orlowski RZ, Kuhn DJ. 2008. Proteasome inhibitors in cancer therapy: Lessons from the first decade. Clin Cancer Res 14:1649-1657.
    • (2008) Clin Cancer Res , vol.14 , pp. 1649-1657
    • Orlowski, R.Z.1    Kuhn, D.J.2
  • 31
    • 33846213525 scopus 로고    scopus 로고
    • Calmodulin-androgen receptor (AR) interaction: Calcium-dependent, calpain- mediated breakdown of AR in LNCaP prostate cancer cells
    • Pelley RP, Chinnakannu K, Murthy S, Strickland FM, Menon M, Dou QP, Barrack ER, Reddy GP. 2006. Calmodulin-androgen receptor (AR) interaction: Calcium-dependent, calpain- mediated breakdown of AR in LNCaP prostate cancer cells. Cancer Res 66:11754-11762.
    • (2006) Cancer Res , vol.66 , pp. 11754-11762
    • Pelley, R.P.1    Chinnakannu, K.2    Murthy, S.3    Strickland, F.M.4    Menon, M.5    Dou, Q.P.6    Barrack, E.R.7    Reddy, G.P.8
  • 32
    • 0034745011 scopus 로고    scopus 로고
    • Control of IkappaBalpha proteolysis by the ubiquitin-proteasome pathway
    • Tanaka K, Kawakami T, Tateishi K, Yashiroda H, Chiba T. 2001. Control of IkappaBalpha proteolysis by the ubiquitin-proteasome pathway. Biochimie 83:351-356.
    • (2001) Biochimie , vol.83 , pp. 351-356
    • Tanaka, K.1    Kawakami, T.2    Tateishi, K.3    Yashiroda, H.4    Chiba, T.5
  • 33
    • 0029077051 scopus 로고
    • Fruit and vegetable consumption and cancer risk in a Mediterranean population
    • Tavani A, La VC. 1995. Fruit and vegetable consumption and cancer risk in a Mediterranean population. Am J Clin Nutr 61:1374S-1377S.
    • (1995) Am J Clin Nutr , vol.61
    • Tavani, A.1    VC, L.2
  • 34
    • 27644452640 scopus 로고    scopus 로고
    • Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
    • Titus MA, Schell MJ, Lih FB, Tomer KB, Mohler JL. 2005. Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res 11:4653-4657.
    • (2005) Clin Cancer Res , vol.11 , pp. 4653-4657
    • Titus, M.A.1    Schell, M.J.2    Lih, F.B.3    Tomer, K.B.4    Mohler, J.L.5
  • 37
    • 0034671668 scopus 로고    scopus 로고
    • HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway
    • Wen Y, Hu MC, Makino K, Spohn B, Bartholomeusz G, Yan DH, Hung MC. 2000. HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway. Cancer Res 60:6841-6845.
    • (2000) Cancer Res , vol.60 , pp. 6841-6845
    • Wen, Y.1    Hu, M.C.2    Makino, K.3    Spohn, B.4    Bartholomeusz, G.5    Yan, D.H.6    Hung, M.C.7
  • 39
    • 0344844481 scopus 로고    scopus 로고
    • Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells
    • Zhang J, Hsu BAJ, Kinseth BAM, Bjeldanes LF, Firestone GL. 2003. Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells. Cancer 98:2511-2520.
    • (2003) Cancer , vol.98 , pp. 2511-2520
    • Zhang, J.1    Hsu, B.A.J.2    Kinseth, B.A.M.3    Bjeldanes, L.F.4    Firestone, G.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.