Catenarin prevents type 1 diabetes in nonobese diabetic mice via inhibition of leukocyte migration involving the MEK6/p38 and MEK7/JNK pathways

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Shen, Ming Yi ^a   Lin, Yu Ping ^b   Yang, Bei Chang ^b   Jang, Yu Song ^a,c   Chiang, Chih Kang ^d   Mettling, Clément ^e   Chen, Zeng Weng ^a   Sheu, Joen Rong ^f   Chang, Cicero L ^g   Lin, Yea Lih ^e   Yang, Wen Chin ^a,c,g  

^a AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN OCEAN UNIVERSITY   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^e INSTITUTE OF HUMAN GENETICS   (France)

^f TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^g NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTHRAQUINONE DERIVATIVE; CASCARIN; CATENARIN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; COMPLEMENTARY DNA; EMODIN; FLUORESCEIN ISOTHIOCYANATE; G PROTEIN COUPLED RECEPTOR; HEMOGLOBIN A1C; HERBACEOUS AGENT; INSULIN ANTIBODY; LENTIVIRUS VECTOR; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE P38; RESVERATROL; RHEIN; STROMAL CELL DERIVED FACTOR 1BETA; UNCLASSIFIED DRUG;

ALTERNATIVE MEDICINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD SAMPLING; CALCIUM CELL LEVEL; CELL LOSS; CHEMOTAXIS; CONTROLLED STUDY; DIABETES CONTROL; DIABETES MELLITUS; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HERB; HUMAN; HUMAN CELL; INFLAMMATION; INFLAMMATORY DISEASE; INSULIN DEPENDENT DIABETES MELLITUS; LEUKEMIA CELL LINE; LEUKOCYTE MIGRATION INHIBITION; MEDICINAL PLANT; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

EID: 84863268602     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/982396     Document Type: Article

References (53)

1. Kikutani H., Makino S., The murine autoimmune diabetes model: NOD and related strains Advances in Immunology 1992 51 285 322
2. Atkinson M. A., Leiter E. H., The NOD mouse model of type 1 diabetes: as good as it gets? Nature Medicine 1999 5 6 601 604 (Pubitemid 29289413)
3. Cha T. L., Qiu L., Chen C. T., Wen Y., Hung M. C., Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth Cancer Research 2005 65 6 2287 2295 (Pubitemid 40490138)
4. O'Reilly L. A., Hutchings P. R., Crocker P. R., Simpson E., Lund T., Kioussis D., Takei F., Baird J., Cooke A., Characterization of pancreatic islet cell infiltrates in NOD mice: effect of cell transfer and transgene expression European Journal of Immunology 1991 21 5 1171 1180
5. Ogasawara K., Hamerman J. A., Hsin H., Chikuma S., Bour-Jordan H., Chen T., Pertel T., Carnaud C., Bluestone J. A., Lanier L. L., Impairment of NK cell function by NKG2D modulation in NOD mice Immunity 2003 18 1 41 51 (Pubitemid 36120686)
6. Eizirik D. L., Colli M. L., Ortis F., The role of inflammation in insulitis and beta-cell loss in type 1 diabetes Nature Reviews Endocrinology 2009 5 4 219 226
7. Atkinson M. A., Brian Wilson S., Fatal attraction: chemokines and type 1 diabetes Journal of Clinical Investigation 2002 110 11 1611 1613 (Pubitemid 35424238)
8. Bradley L. M., Asensio V. C., Schioetz L. K., Harbertson J., Krahl T., Patstone G., Woolf N., Campbell I. L., Sarvetnick N., Islet-specific Th1, but not Th2, cells secrete multiple chemokines and promote rapid induction of autoimmune diabetes Journal of Immunology 1999 162 5 2511 2520 (Pubitemid 29309268)
9. Cameron M. J., Arreaza G. A., Grattan M., Meagher C., Sharif S., Burdick M. D., Strieter R. M., Cook D. N., Delovitch T. L., Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes Journal of Immunology 2000 165 2 1102 1110 (Pubitemid 30484782)
10. Meagher C., Sharif S., Hussain S., Cameron M. J., Arreaza G. A., Delovitch T. L., Cytokines and chemokines in the pathogenesis of murine type 1 diabetes Advances in Experimental Medicine and Biology 2003 520 133 158 (Pubitemid 36532476)
11. Jin T., Xu X., Hereld D., Chemotaxis, chemokine receptors and human disease Cytokine 2008 44 1 1 8
12. Pease J. E., Williams T. J., The attraction of chemokines as a target for specific anti-inflammatory therapy British Journal of Pharmacology 2006 147, supplement 1 1 S212 S221 (Pubitemid 43077279)
13. Turner J. E., Steinmetz O. M., Stahl R. A., Panzer U., Targeting of Th1-associated chemokine receptors CXCR3 and CCR5 as therapeutic strategy for inflammatory diseases Mini-Reviews in Medicinal Chemistry 2007 7 11 1089 1096 (Pubitemid 350217999)
14. Christen U., Chemokines as drug targets in type 1 diabetes Endocrine, Metabolic Immune DisordersDrug Targets 2007 7 1 7 12 (Pubitemid 46380413)
15. Proudfoot A. E. I., Chemokine receptors: multifaceted therapeutic targets Nature Reviews Immunology 2002 2 2 106 115 (Pubitemid 37323234)
16. Toyoda H., Formby B., Contribution of T cells to the development of autoimmune diabetes in the NOD mouse model Bioessays 1998 20 9 750 757 (Pubitemid 28485902)
17. Bromley S. K., Mempel T. R., Luster A. D., Orchestrating the orchestrators: chemokines in control of T cell traffic Nature Immunology 2008 9 9 970 980
18. Aboumrad E., Madec A. M., Thivolet C., The CXCR4/CXCL12 (SDF-1) signalling pathway protects non-obese diabetic mouse from autoimmune diabetes Clinical Experimental Immunology 2007 148 3 432 439 (Pubitemid 46701033)
19. Carvalho-Pinto C., Garca M. I., Gmez L., Ballesteros A., Zaballos A., Flores J. M., Mellado M., Rodrguez-Frade J., Balomenos D., Martnez C. C., Leukocyte attraction through the CCR5 receptor controls progress from insulitis to diabetes in non-obese diabetic mice European Journal of Immunology 2004 34 2 548 557 (Pubitemid 39272795)
20. Hagemann C., Patel R., Blank J. L., MEKK3 interacts with the PA28 regulatory subunit of the proteasome Biochemical Journal 2003 373, part 1 71 79 (Pubitemid 36819503)
21. Murdoch C., Finn A., Chemokine receptors and their role in inflammation and infectious diseases Blood 2000 95 10 3032 3043 (Pubitemid 30321151)
22. Beales P. E., Williams A., Krug J., Signore A., Chianelli M., Andreani D., Pozzilli P., Effecs of Tenidap, a novel anti-inflammatory compound on islet lymphocytic infiltration and diabetes incidence in the non obese diabetic (NOD) mouse Diabete et Metabolisme 1992 18 1 48 53
23. Yang Z., Chen M., Fialkow L. B., Ellett J. D., Wu R., Nadler J. L., The novel anti-inflammatory compound, lisofylline, prevents diabetes in multiple low-dose streptozotocin-treated mice Pancreas 2003 26 4 e99 e104
24. Chang C. L. T., Kuo H. K., Chang S. L., Chiang Y. M., Lee T. H., Wu W. M., Shyur L. F., Yang W. C., The distinct effects of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice Journal of Biomedical Science 2005 12 1 79 89
25. Gysemans C., Stoffels K., Giulietti A., Overbergh L., Waer M., Lannoo M., Feige U., Mathieu C., Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agents Diabetologia 2003 46 8 1115 1123 (Pubitemid 37041242)
26. Ganesan A., The impact of natural products upon modern drug discovery Current Opinion in Chemical Biology 2008 12 3 306 317
27. Xie W., Du L., Diabetes is an inflammatory disease: evidence from traditional Chinese medicines Diabetes, Obesity and Metabolism 2011 13 4 289 301
28. Lin S. Y., Lai W. W., Ho C. C., Yu F. S., Chen G. W., Yang J. S., Liu K. C., Lin M. L., Wu P. P., Fan M. J., Chung J. G., Eniodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways Anticancer Research 2009 29 1 327 335
29. Chang L. C., Sheu H. M., Huang Y. S., Tsai T. R., Kuo K. W., A novel function of emodin. Enhancement of the nucleotide excision repair of UV- and cisplatin-induced DNA damage in human cells Biochemical Pharmacology 1999 58 1 49 57
30. Ding Y., Zhao L., Mei H., Zhang S. L., Huang Z. H., Duan Y. Y., Ye P., Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway European Journal of Pharmacology 2008 590 13 377 386
31. Matsuda H., Shimoda H., Morikawa T., Yoshikawa M., Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity Bioorganic Medicinal Chemistry Letters 2001 11 14 1839 1842 (Pubitemid 32675300)
32. Li Z. F., Xia X. M., Huang C., Zhang S., Zhang J., Zhang A. J., Emodin and baicalein inhibit pancreatic stromal derived factor-1 expression in rats with acute pancreatitis Hepatobiliary Pancreatic Diseases International 2009 8 2 201 208
33. Kumar A., Dhawan S., Aggarwal B. B., Emodin (3-methyl-1,6,8- trihydroxyanthraquinone) inhibits TNF-induced NF- B activation, I B degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells Oncogene 1998 17 7 913 918 (Pubitemid 28430214)
34. Nguyen M., Dougados M., Berdah L., Amor B., Diacerhein in the treatment of osteoarthritis of the hip Arthritis Rheumatism 1994 37 4 529 536 (Pubitemid 24115939)
35. Desmetz C., Lin Y. L., Mettling C., Portals P., Nol D., Clot J., Jorgensen C., Corbeau P., Cell surface CCR5 density determines the intensity of T cell migration towards rheumatoid arthritis synoviocytes Clinical Immunology 2007 123 2 148 154 (Pubitemid 46590072)
36. Chang S. L., Chang C. L. T., Huang P. I., Tao M. H., Yang W. C., Role of Cybr, a cytohesin binder and regulator, in CD4 + T-cell function and host immunity Molecular Immunology 2009 46 16 3218 3223
37. Barreiro O., Martn P., Gonzlez-Amaro R., Snchez-Madrid F., Molecular cues guiding inflammatory responses Cardiovascular Research 2010 86 2 174 182
38. Zengel P., Nguyen-Hoang A., Schildhammer C., Zantl R., Kahl V., Horn E., μ-slide chemotaxis: a new chamber for long-term chemotaxis studies BMC Cell Biology 2011 12 1, article 21
39. Foltz I. N., Gerl R. E., Wieler J. S., Luckach M., Salmon R. A., Schrader J. W., Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli Journal of Biological Chemistry 1998 273 15 9344 9351 (Pubitemid 28176230)
40. Hickson J. A., Huo D., Vander Griend D. J., Lin A., Rinker-Schaeffer C. W., Yamada S. D., The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma Cancer Research 2006 66 4 2264 2270
41. Stern F. H., Constipationan omnipresent symptom: effect of a preparation containing prune concentrate and cascarin Journal of the American Geriatrics Society 1966 14 11 1153 1155
42. Srinivas G., Babykutty S., Sathiadevan P. P., Srinivas P., Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent Medicinal Research Reviews 2007 27 5 591 608 (Pubitemid 47282445)
43. Franz G., The senna drug and its chemistry Pharmacology 1993 47 1 2 6 (Pubitemid 23291008)
44. Lai J. M., Chang J. T., Wen C. L., Hsu S. L., Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells European Journal of Pharmacology 2009 623 13 1 9
45. Das S., Das D. K., Anti-inflammatory responses of resveratrol Inflammation and AllergyDrug Targets 2007 6 3 168 173 (Pubitemid 47455785)
46. Malaguti C., Vilella C. A., Vieira K. P., Souza G. H. M. F., Hyslop S., Zollner R. D. L., Diacerhein downregulate proinflammatory cytokines expression and decrease the autoimmune diabetes frequency in nonobese diabetic (NOD) mice International Immunopharmacology 2008 8 6 782 791
47. Horuk R., Promiscuous drugs as therapeutics for chemokine receptors Expert Reviews in Molecular Medicine 2009 11 e1
48. Solomon M., Balasa B., Sarvetnick N., CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse Autoimmunity 2010 43 2 156 163
49. Rozengurt E., Mitogenic signaling pathways induced by G protein-coupled receptors Journal of Cellular Physiology 2007 213 3 589 602 (Pubitemid 350058250)
50. Kwak H. J., Park M. J., Park C. M., Moon S. I., Yoo D. H., Lee H. C., Lee S. H., Kim M. S., Lee H. W., Shin W. S., Park I. C., Rhee C. H., Hong S. I., Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation International Journal of Cancer 2006 118 11 2711 2720 (Pubitemid 43673348)
51. Kaneshiro T., Morioka T., Inamine M., Kinjo T., Arakaki J., Chiba I., Sunagawa N., Suzui M., Yoshimi N., Anthraquinone derivative emodin inhibits tumor-associated angiogenesis through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation European Journal of Pharmacology 2006 553 13 46 53 (Pubitemid 44779599)
52. Carruba G., Cocciadiferro L., Bellavia V., Rizzo S., Tsatsanis C., Spandidos D., Muti P., Smith C., Mehta P., Castagnetta L., Intercellular communication and human hepatocellular carcinoma Annals of the New York Academy of Sciences 2004 1028 202 212 (Pubitemid 40361823)
53. Montero M., Lobaton C. D., Moreno A., Alvarez J., A novel regulatory mechanism of the mitochondrial Ca 2+ uniporter revealed by the p38 mitogen-activated protein kinase inhibitor SB202190 The FASEB Journal 2002 16 14 1955 1957