The C-terminal proteolytic fragment of the breast cancer susceptibility type 1 protein (BRCA1) is degraded by the N-end rule pathway

Journal of Biological Chemistry

Volumn 287, Issue 10, 2012, Pages 7495-7502

  Xu, Zhizhong ^a   Payoe, Roshani ^a   Fahlman, Richard P ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC PATHWAYS; ASPARTATES; BREAST CANCER; C-TERMINAL FRAGMENTS; CASPASES; GENE PRODUCTS; N-TERMINALS; PROTEOLYTIC FRAGMENTS; WILD TYPES;

CELL DEATH; DISEASES; GENES;

AMINO ACIDS;

ARGININE; ARGININE TRANSFER RNA TRANSFERASE; ASPARTIC ACID; BRCA1 PROTEIN; TRANSFERASE; UNCLASSIFIED DRUG; VALINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL TYPE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BRCA1 PROTEIN; CASPASES; CELL DEATH; HELA CELLS; HUMANS; MICE; MICE, KNOCKOUT; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEOLYSIS;

EID: 84863249152     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.301002     Document Type: Article

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