An alternative mechanism for the catalysis of peptide bond formation by L/F transferase: Substrate binding and orientation

Journal of Molecular Biology

Volumn 409, Issue 4, 2011, Pages 617-629

  Fung, Angela W ^a   Ebhardt, H Alexander ^a,b   Abeysundara, Heshani ^a   Moore, Jack ^a   Xu, Zhizhong ^a   Fahlman, Richard P ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b ETH ZURICH   (Switzerland)

Author keywords

aminoacyl tRNA transferase; L F transferase; leucyltransferase; N end rule; peptide bond formation

Indexed keywords

AMINOACYL TRANSFER RNA; ESCHERICHIA COLI PROTEIN; LEUCINE TRANSFER RNA; LEUCYL TRANSFER RNA TRANSFERASE; PHENYLALANINE; PHENYLALANINE TRANSFER RNA; PHENYLALANYL TRANSFER RNA TRANSFERASE; TRANSFER RNA; TRANSFERASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; CATALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; ESCHERICHIA COLI; ISOTOPE LABELING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PEPTIDE ANALYSIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; STEREOCHEMISTRY; STRUCTURE ANALYSIS; X RAY ANALYSIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 79957773104     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.04.033     Document Type: Article

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