-
1
-
-
77951916908
-
Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery
-
Grigsby CL, Leong KW. Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery. J R Soc Interface 2010; 7(Suppl 1): S67-S82.
-
(2010)
J R Soc Interface
, vol.7
, Issue.SUPPL. 1
-
-
Grigsby, C.L.1
Leong, K.W.2
-
2
-
-
22144447455
-
Design and development of polymers for gene delivery
-
Pack DW, Hoffman AS, Pun S, et al. Design and development of polymers for gene delivery. Nat Rev Drug Discov 2005; 4: 581-593.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 581-593
-
-
Pack, D.W.1
Hoffman, A.S.2
Pun, S.3
-
3
-
-
69949157316
-
Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes
-
Won YY, Sharma R, Konieczny SF. Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes. J Control Release 2009; 139: 88-93.
-
(2009)
J Control Release
, vol.139
, pp. 88-93
-
-
Won, Y.Y.1
Sharma, R.2
Konieczny, S.F.3
-
4
-
-
14744301443
-
Controlling the kinetics of transgene expression by plasmid design
-
Yew NS. Controlling the kinetics of transgene expression by plasmid design. Adv Drug Deliv Rev 2005; 57: 769-780.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 769-780
-
-
Yew, N.S.1
-
5
-
-
0034623971
-
Local and systemic inoculation of DNA or protein gB1s-based vaccines induce a protective immunity against rabbit ocular HSV-1 infection
-
Caselli E, Balboni PG, Incorvaia C, et al. Local and systemic inoculation of DNA or protein gB1s-based vaccines induce a protective immunity against rabbit ocular HSV-1 infection. Vaccine 2000; 19: 1225-1231.
-
(2000)
Vaccine
, vol.19
, pp. 1225-1231
-
-
Caselli, E.1
Balboni, P.G.2
Incorvaia, C.3
-
6
-
-
59249092022
-
Muscular gene transfer using nonviral vectors
-
Braun S. Muscular gene transfer using nonviral vectors. Curr Gene Ther 2008; 8: 391-405.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 391-405
-
-
Braun, S.1
-
7
-
-
42149116854
-
Bioadhesive hyaluronan-chitosan nanoparticles can transport genes across the ocular mucosa and transfect ocular tissue
-
de la Fuente M, Seijo B, Alonso MJ. Bioadhesive hyaluronan-chitosan nanoparticles can transport genes across the ocular mucosa and transfect ocular tissue. Gene Ther 2008; 15: 668-676.
-
(2008)
Gene Ther
, vol.15
, pp. 668-676
-
-
de la Fuente, M.1
Seijo, B.2
Alonso, M.J.3
-
8
-
-
50549090204
-
Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression
-
Lufino MM, Edser PA, Wade-Martins R. Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression. Mol Ther 2008; 16: 1525-1538.
-
(2008)
Mol Ther
, vol.16
, pp. 1525-1538
-
-
Lufino, M.M.1
Edser, P.A.2
Wade-Martins, R.3
-
9
-
-
73449101112
-
Recent trends in non-viral vector-mediated gene delivery
-
Pathak A, Patnaik S, Gupta KC. Recent trends in non-viral vector-mediated gene delivery. Biotechnol J 2009; 4: 1559-1572.
-
(2009)
Biotechnol J
, vol.4
, pp. 1559-1572
-
-
Pathak, A.1
Patnaik, S.2
Gupta, K.C.3
-
10
-
-
77955272031
-
Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery
-
Navarro G, Maiwald G, Haase R, et al. Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery. J Control Release 2010; 146: 99-105.
-
(2010)
J Control Release
, vol.146
, pp. 99-105
-
-
Navarro, G.1
Maiwald, G.2
Haase, R.3
-
11
-
-
67650281456
-
Designing plasmid vectors
-
Tolmachov O. Designing plasmid vectors. Methods Mol Biol 2009; 542: 117-129.
-
(2009)
Methods Mol Biol
, vol.542
, pp. 117-129
-
-
Tolmachov, O.1
-
12
-
-
49749152440
-
Characterization of the transgene expression generated by branched and linear polyethylenimine-plasmid DNA nanoparticles in vitro and after intraperitoneal injection in vivo
-
Intra J, Salem AK. Characterization of the transgene expression generated by branched and linear polyethylenimine-plasmid DNA nanoparticles in vitro and after intraperitoneal injection in vivo. J Control Release 2008; 130: 129-138.
-
(2008)
J Control Release
, vol.130
, pp. 129-138
-
-
Intra, J.1
Salem, A.K.2
-
13
-
-
73249137078
-
Ultrapure chitosan oligomers as carriers for corneal gene transfer
-
Klausner EA, Zhang Z, Chapman RL, et al. Ultrapure chitosan oligomers as carriers for corneal gene transfer. Biomaterials 2010; 31: 1814-1820.
-
(2010)
Biomaterials
, vol.31
, pp. 1814-1820
-
-
Klausner, E.A.1
Zhang, Z.2
Chapman, R.L.3
-
14
-
-
48949098577
-
Gene therapy progress and prospects: synthetic polymer-based systems
-
Schaffert D, Wagner E. Gene therapy progress and prospects: synthetic polymer-based systems. Gene Ther 2008; 15: 1131-1138.
-
(2008)
Gene Ther
, vol.15
, pp. 1131-1138
-
-
Schaffert, D.1
Wagner, E.2
-
15
-
-
67650036224
-
Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes
-
Williams JA, Luke J, Langtry S, et al. Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes. Biotechnol Bioeng 2009; 103: 1129-1143.
-
(2009)
Biotechnol Bioeng
, vol.103
, pp. 1129-1143
-
-
Williams, J.A.1
Luke, J.2
Langtry, S.3
-
16
-
-
0034670157
-
The role of CpG motifs in immunostimulation and gene therapy
-
Scheule RK. The role of CpG motifs in immunostimulation and gene therapy. Adv Drug Deliv Rev 2000; 44: 119-134.
-
(2000)
Adv Drug Deliv Rev
, vol.44
, pp. 119-134
-
-
Scheule, R.K.1
-
17
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg AM, Yi AK, Matson S, et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995; 374: 546-549.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
-
19
-
-
77950339265
-
The effect of CpG motifs on gene expression and clearance kinetics of aerosol administered polyethylenimine (PEI)-plasmid DNA complexes in the lung
-
Lesina E, Dames P, Rudolph C. The effect of CpG motifs on gene expression and clearance kinetics of aerosol administered polyethylenimine (PEI)-plasmid DNA complexes in the lung. J Control Release 2010; 143: 243-250.
-
(2010)
J Control Release
, vol.143
, pp. 243-250
-
-
Lesina, E.1
Dames, P.2
Rudolph, C.3
-
20
-
-
43449111490
-
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression
-
Hyde SC, Pringle IA, Abdullah S, et al. CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression. Nat Biotechnol 2008; 26: 549-551.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 549-551
-
-
Hyde, S.C.1
Pringle, I.A.2
Abdullah, S.3
-
21
-
-
15944400651
-
Towards safe, non-viral therapeutic gene expression in humans
-
Glover DJ, Lipps HJ, Jans DA. Towards safe, non-viral therapeutic gene expression in humans. Nat Rev Genet 2005; 6: 299-310.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 299-310
-
-
Glover, D.J.1
Lipps, H.J.2
Jans, D.A.3
-
22
-
-
68649119307
-
Strategies for the episomal modification of cells
-
Wong SP, Argyros O, Coutelle C, et al. Strategies for the episomal modification of cells. Curr Opin Mol Ther 2009; 11: 433-441.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 433-441
-
-
Wong, S.P.1
Argyros, O.2
Coutelle, C.3
-
23
-
-
0037429043
-
Optimization of cis-acting elements for gene expression from nonviral vectors in vivo
-
Ehrhardt A, Peng PD, Xu H, et al. Optimization of cis-acting elements for gene expression from nonviral vectors in vivo. Hum Gene Ther 2003; 14: 215-225.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 215-225
-
-
Ehrhardt, A.1
Peng, P.D.2
Xu, H.3
-
24
-
-
57049172006
-
Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector
-
Argyros O, Wong SP, Niceta M, et al. Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector. Gene Ther 2008; 15: 1593-1605.
-
(2008)
Gene Ther
, vol.15
, pp. 1593-1605
-
-
Argyros, O.1
Wong, S.P.2
Niceta, M.3
-
26
-
-
77954283440
-
Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency
-
Jiang X, Zheng Y, Chen HH, et al. Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency. Adv Mater 2010; 22: 2556-2560.
-
(2010)
Adv Mater
, vol.22
, pp. 2556-2560
-
-
Jiang, X.1
Zheng, Y.2
Chen, H.H.3
-
27
-
-
5444267326
-
Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers
-
Koping-Hoggard M, Varum KM, Issa M, et al. Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers. Gene Ther 2004; 11: 1441-1452.
-
(2004)
Gene Ther
, vol.11
, pp. 1441-1452
-
-
Koping-Hoggard, M.1
Varum, K.M.2
Issa, M.3
-
28
-
-
77952670572
-
Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation
-
Mohri K, Okuda T, Mori A, et al. Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation. J Control Release 2010; 144: 221-226.
-
(2010)
J Control Release
, vol.144
, pp. 221-226
-
-
Mohri, K.1
Okuda, T.2
Mori, A.3
-
29
-
-
33845876613
-
Optimization and delivery of plasmid DNA for vaccination
-
Jechlinger W. Optimization and delivery of plasmid DNA for vaccination. Expert Rev Vaccines 2006; 5: 803-825.
-
(2006)
Expert Rev Vaccines
, vol.5
, pp. 803-825
-
-
Jechlinger, W.1
-
30
-
-
38649139896
-
Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose
-
Wu Z, Sun J, Zhang T, et al. Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose. Mol Ther 2008; 16: 280-289.
-
(2008)
Mol Ther
, vol.16
, pp. 280-289
-
-
Wu, Z.1
Sun, J.2
Zhang, T.3
-
31
-
-
77953128888
-
Immune response induced by a linear DNA vector: influence of dose, formulation and route of injection
-
Endmann A, Baden M, Weisermann E, et al. Immune response induced by a linear DNA vector: influence of dose, formulation and route of injection. Vaccine 2010; 28: 3642-3649.
-
(2010)
Vaccine
, vol.28
, pp. 3642-3649
-
-
Endmann, A.1
Baden, M.2
Weisermann, E.3
-
32
-
-
77649275936
-
A nonviral minicircle vector for deriving human iPS cells
-
Jia F, Wilson KD, Sun N, et al. A nonviral minicircle vector for deriving human iPS cells. Nat Methods 2010; 7: 197-199.
-
(2010)
Nat Methods
, vol.7
, pp. 197-199
-
-
Jia, F.1
Wilson, K.D.2
Sun, N.3
-
33
-
-
27744574546
-
Promoter- and strain-selective enhancement of gene expression in a mouse skeletal muscle by a polymer excipient Pluronic P85
-
Yang Z, Zhu J, Sriadibhatla S, et al. Promoter- and strain-selective enhancement of gene expression in a mouse skeletal muscle by a polymer excipient Pluronic P85. J Control Release 2005; 108: 496-512.
-
(2005)
J Control Release
, vol.108
, pp. 496-512
-
-
Yang, Z.1
Zhu, J.2
Sriadibhatla, S.3
-
34
-
-
0030452942
-
Pulmonary response to plasmid DNA and immunohistochemical localization of transgene expression
-
Tsan MF, White JE, Pastore JN, et al. Pulmonary response to plasmid DNA and immunohistochemical localization of transgene expression. Exp Lung Res 1996; 22: 651-666.
-
(1996)
Exp Lung Res
, vol.22
, pp. 651-666
-
-
Tsan, M.F.1
White, J.E.2
Pastore, J.N.3
-
35
-
-
62549107464
-
Nonviral delivery for genomic therapy of cancer
-
Templeton NS. Nonviral delivery for genomic therapy of cancer. World J Surg 2009; 33: 685-697.
-
(2009)
World J Surg
, vol.33
, pp. 685-697
-
-
Templeton, N.S.1
-
36
-
-
45749158576
-
Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes
-
Davies LA, McLachlan G, Sumner-Jones SG, et al. Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes. Mol Ther 2008; 16: 1283-1290.
-
(2008)
Mol Ther
, vol.16
, pp. 1283-1290
-
-
Davies, L.A.1
McLachlan, G.2
Sumner-Jones, S.G.3
-
37
-
-
64549134676
-
Nonviral vectors for gene delivery
-
Mintzer MA, Simanek EE. Nonviral vectors for gene delivery. Chem Rev 2009; 109: 259-302.
-
(2009)
Chem Rev
, vol.109
, pp. 259-302
-
-
Mintzer, M.A.1
Simanek, E.E.2
-
38
-
-
77955281352
-
Gene delivery mediated by recombinant silk proteins containing cationic and cell binding motifs
-
Numata K, Hamasaki J, Subramanian B, et al. Gene delivery mediated by recombinant silk proteins containing cationic and cell binding motifs. J Control Release 2010; 146: 136-143.
-
(2010)
J Control Release
, vol.146
, pp. 136-143
-
-
Numata, K.1
Hamasaki, J.2
Subramanian, B.3
-
39
-
-
33746238252
-
In vivo electroporation and ubiquitin promoter - a protocol for sustained gene expression in the lung
-
Gazdhar A, Bilici M, Pierog J, et al. In vivo electroporation and ubiquitin promoter - a protocol for sustained gene expression in the lung. J Gene Med 2006; 8: 910-918.
-
(2006)
J Gene Med
, vol.8
, pp. 910-918
-
-
Gazdhar, A.1
Bilici, M.2
Pierog, J.3
-
40
-
-
36048987779
-
-
BMJ Books: London
-
Coster DJ. Cornea. BMJ Books: London, 2002.
-
(2002)
Cornea
-
-
Coster, D.J.1
|