Activation of hypoxia-inducible factor by cobalt is associated with the attenuation of tissue injury and apoptosis in cyclosporine-induced nephropathy

Tohoku Journal of Experimental Medicine

Volumn 226, Issue 3, 2012, Pages 197-206

  Oh, Se Won ^a   Ahn, Jeong Myung ^b   Lee, Yun Mi ^a   Kim, Sejoong ^a,c   Chin, Ho Jun ^a,c   Chae, Dong Wan ^a,c   Na, Ki Young ^a,c  

^a Seoul National University Bundang Hospital   (South Korea)

^b Maryknoll Hospital   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

Apoptosis; Cyclosporine; Fibrosis; Hypoxia inducible factor 1; Inflammation

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CASPASE 3; COBALT; CYCLOSPORIN; HYPOXIA INDUCIBLE FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTERIOLOPATHY; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTERSTITIAL NEPHRITIS; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY INTERSTITIUM; MACROPHAGE; MALE; MONOCYTE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RENAL TUBULOINTERSTITIUM; SODIUM RESTRICTION; TISSUE INJURY;

ANIMALS; APOPTOSIS; CELL LINE; COBALT; CYCLOSPORINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOSUPPRESSIVE AGENTS; KIDNEY DISEASES; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84863146905     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.226.197     Document Type: Article

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