메뉴 건너뛰기




Volumn 53, Issue 12, 2005, Pages 1459-1468

Provinol pevents CsA-induced nephrotoxicity by reducing reactive oxygen species, iNOS, and NF-kB expression

Author keywords

Fibrosis; Kidney; Provinol; ROS

Indexed keywords

ALKADIENE; CREATININE; CYCLOSPORIN A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; OLIVE OIL; POLYPHENOL; PROVINOL; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CYCLOSPORIN; FLAVONOID; PHENOL DERIVATIVE; POLYPHENOLS;

EID: 28344443973     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.5A6623.2005     Document Type: Article
Times cited : (54)

References (52)
  • 1
    • 0027454175 scopus 로고
    • Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine a and FK-506 in rat and human liver microsomes
    • Ahmed SS, Strobel HW, Napoli KL, Grevel J (1993) Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes. J Pharmacol Exp Ther 265:1047-1054
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1047-1054
    • Ahmed, S.S.1    Strobel, H.W.2    Napoli, K.L.3    Grevel, J.4
  • 4
    • 0141618437 scopus 로고    scopus 로고
    • Attenuation of cyclosporine-induced renal dysfunction by catechin: Possible antioxidant mechanism
    • Anjaneyulu M, Tirkey N, Chopra K (2003) Attenuation of cyclosporine-induced renal dysfunction by catechin: possible antioxidant mechanism. Ren Fail 25:691-707
    • (2003) Ren Fail , vol.25 , pp. 691-707
    • Anjaneyulu, M.1    Tirkey, N.2    Chopra, K.3
  • 7
    • 5444267958 scopus 로고    scopus 로고
    • Amelioration of cyclosporine nephrotoxicity by irbesartan, a selective AT1 receptor antagonist
    • Chander V, Singh D, Tirkey N, Chander H, Chopra K (2004) Amelioration of cyclosporine nephrotoxicity by irbesartan, a selective AT1 receptor antagonist. Ren Fail 26:467-477
    • (2004) Ren Fail , vol.26 , pp. 467-477
    • Chander, V.1    Singh, D.2    Tirkey, N.3    Chander, H.4    Chopra, K.5
  • 8
    • 0036854528 scopus 로고    scopus 로고
    • Cyclosporine a regulate oxidative stress-induced apoptosis in cardiomyocytes: Mechanisms via ROS generation, iNOS and Hsp70
    • Chen HW, Chien CT, Yu SL, Lee YT, Chen WS (2002) Cyclosporine A regulate oxidative stress-induced apoptosis in cardiomyocytes: mechanisms via ROS generation, iNOS and Hsp70. Br J Pharmacol 137:771-781
    • (2002) Br J Pharmacol , vol.137 , pp. 771-781
    • Chen, H.W.1    Chien, C.T.2    Yu, S.L.3    Lee, Y.T.4    Chen, W.S.5
  • 9
    • 0036080603 scopus 로고    scopus 로고
    • Peroxynitrite increases iNOS through NF-kB and decreases prostacyclin synthase in endothelial cells
    • Cooke CL, Davidge ST (2002) Peroxynitrite increases iNOS through NF-kB and decreases prostacyclin synthase in endothelial cells. Am J Physiol Cell Physiol 282:395-402
    • (2002) Am J Physiol Cell Physiol , vol.282 , pp. 395-402
    • Cooke, C.L.1    Davidge, S.T.2
  • 10
    • 0031983495 scopus 로고    scopus 로고
    • Impaired antioxidant defense system in the kidney tissues from rabbits treated with cyclosporine. Protective effects of vitamins e and C
    • Durak I, Karabacak HI, Buyukkocak S, Cimen MY, Kacmaz M, Omeroglu E, Ozturk HS (1998) Impaired antioxidant defense system in the kidney tissues from rabbits treated with cyclosporine. Protective effects of vitamins E and C. Nephron 78:207-211
    • (1998) Nephron , vol.78 , pp. 207-211
    • Durak, I.1    Karabacak, H.I.2    Buyukkocak, S.3    Cimen, M.Y.4    Kacmaz, M.5    Omeroglu, E.6    Ozturk, H.S.7
  • 12
    • 1642282731 scopus 로고    scopus 로고
    • Cyclosporine reduces hepatic antioxidant capacity: Protective roles of antioxidants
    • Durak I, Ozbek H, Elgun S (2004) Cyclosporine reduces hepatic antioxidant capacity: protective roles of antioxidants. Int Immunopharmacol 4:469-473
    • (2004) Int Immunopharmacol , vol.4 , pp. 469-473
    • Durak, I.1    Ozbek, H.2    Elgun, S.3
  • 13
    • 0348047623 scopus 로고    scopus 로고
    • The beneficial effect of melatonin on chronic cyclosporin a nephrotoxicity in rats
    • Esrefoglu M, Kurus M, Sahna E (2003) The beneficial effect of melatonin on chronic cyclosporin A nephrotoxicity in rats. J Int Med Res 31:42-44
    • (2003) J Int Med Res , vol.31 , pp. 42-44
    • Esrefoglu, M.1    Kurus, M.2    Sahna, E.3
  • 14
    • 0141639855 scopus 로고    scopus 로고
    • Antioxidant activity of tea polyphenols in vivo: Evidence from animal studies
    • Frei B, Higdon JV (2003) Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J Nutr 133:32755-32845
    • (2003) J Nutr , vol.133 , pp. 32755-32845
    • Frei, B.1    Higdon, J.V.2
  • 15
    • 0031389884 scopus 로고    scopus 로고
    • Vitamin e may slow kidney failure owing to oxidative stress
    • Fryer MJ (1997) Vitamin E may slow kidney failure owing to oxidative stress. Redox Rep 3:259-261
    • (1997) Redox Rep , vol.3 , pp. 259-261
    • Fryer, M.J.1
  • 17
    • 0032101249 scopus 로고    scopus 로고
    • Attenuation of iron-nitrilotriacetate (FeNTA)-mediated renal oxidative stress, toxicity and hyperproliferative response by the prophylactic treatment of rats with garlic oil
    • Iqbal M, Athar M (1998) Attenuation of iron-nitrilotriacetate (FeNTA)-mediated renal oxidative stress, toxicity and hyperproliferative response by the prophylactic treatment of rats with garlic oil. Food Chem Toxicol 36:485-495
    • (1998) Food Chem Toxicol , vol.36 , pp. 485-495
    • Iqbal, M.1    Athar, M.2
  • 18
    • 0033861887 scopus 로고    scopus 로고
    • Anti-apoptotic effect of quercetin: Intervention in the JNK- and ERK-mediated apoptotic pathways
    • Ishikawa Y, Kitamura M (2000) Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways. Kidney Int 58:1078-1087
    • (2000) Kidney Int , vol.58 , pp. 1078-1087
    • Ishikawa, Y.1    Kitamura, M.2
  • 19
    • 0024976004 scopus 로고
    • Cyclosporine
    • Kahan BD (1989) Cyclosporine. N Engl J Med 321:1725-1738
    • (1989) N Engl J Med , vol.321 , pp. 1725-1738
    • Kahan, B.D.1
  • 20
    • 0033894949 scopus 로고    scopus 로고
    • Increased activity of nuclear factor-kappaB participates in cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis in rats
    • Kitamoto S, Egashira K, Kataoka C, Koyanagi M, Katoh M, Shimokawa H, Morishita R, et al. (2000) Increased activity of nuclear factor-kappaB participates in cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis in rats. Circulation 102:806-812
    • (2000) Circulation , vol.102 , pp. 806-812
    • Kitamoto, S.1    Egashira, K.2    Kataoka, C.3    Koyanagi, M.4    Katoh, M.5    Shimokawa, H.6    Morishita, R.7
  • 21
    • 0019991219 scopus 로고
    • Potentiation of lipid peroxides by ischemia in rat brain
    • Kogure K, Watson BD, Busto R, Abe K (1982) Potentiation of lipid peroxides by ischemia in rat brain. Neurochem Res 7:437-454
    • (1982) Neurochem Res , vol.7 , pp. 437-454
    • Kogure, K.1    Watson, B.D.2    Busto, R.3    Abe, K.4
  • 22
    • 0032843957 scopus 로고    scopus 로고
    • In vitro models to study mechanisms involved in cyclosporine A-mediated glomerular contraction
    • L'Azou B, Medina J, Frieauff W, Cordier A, Cambar J, Wolf A (1999) In vitro models to study mechanisms involved in cyclosporine A-mediated glomerular contraction. Arch Toxicol 73:337-345
    • (1999) Arch Toxicol , vol.73 , pp. 337-345
    • L'Azou, B.1    Medina, J.2    Frieauff, W.3    Cordier, A.4    Cambar, J.5    Wolf, A.6
  • 24
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease and cancer
    • Middleton E, Kandaswami C, Theoharides TC (2000) The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer. Pharmacol Rev 52:673-751
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton, E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 25
    • 0037090211 scopus 로고    scopus 로고
    • Superoxide limits cyclosporine-A-induced formation of peroxynitrite in endothelial cells (2)
    • Navarro-Antolin J, Lopez-Munoz MJ, Soria J, Lamas S (2002) Superoxide limits cyclosporine-A-induced formation of peroxynitrite in endothelial cells (2). Free Radic Biol Med 32:702-711
    • (2002) Free Radic Biol Med , vol.32 , pp. 702-711
    • Navarro-Antolin, J.1    Lopez-Munoz, M.J.2    Soria, J.3    Lamas, S.4
  • 26
    • 0036357389 scopus 로고    scopus 로고
    • Salvage of cyclosporine A-induced oxidative stress and renal dysfunction by carvedilol
    • Padi SS, Chopra K (2002) Salvage of cyclosporine A-induced oxidative stress and renal dysfunction by carvedilol. Nephron 92:685-692
    • (2002) Nephron , vol.92 , pp. 685-692
    • Padi, S.S.1    Chopra, K.2
  • 28
    • 0032573524 scopus 로고    scopus 로고
    • Cyclosporine increases local glomerular synthesis of reactive oxygen species in rats: Effect of vitamin e on cyclosporine nephrotoxicity
    • Parra T, de Arriba G, Conejo JR, Cantero M, Arribas I, Rodriguez-Puyol D, Rodriguez-Puyol M, et al. (1998b) Cyclosporine increases local glomerular synthesis of reactive oxygen species in rats: effect of vitamin E on cyclosporine nephrotoxicity. Transplantation 66:1325-1329
    • (1998) Transplantation , vol.66 , pp. 1325-1329
    • Parra, T.1    De Arriba, G.2    Conejo, J.R.3    Cantero, M.4    Arribas, I.5    Rodriguez-Puyol, D.6    Rodriguez-Puyol, M.7
  • 33
    • 14644386805 scopus 로고    scopus 로고
    • Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity
    • Polytarchou C, Papadimitriou E (2005) Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity. Eur J Pharmacol 510:31-38
    • (2005) Eur J Pharmacol , vol.510 , pp. 31-38
    • Polytarchou, C.1    Papadimitriou, E.2
  • 34
    • 0034750538 scopus 로고    scopus 로고
    • Induction of endothelin in rat kidney after cyclosporine a treatment
    • Rezzani R, Rodella L, Biachi R (2001) Induction of endothelin in rat kidney after cyclosporine A treatment. Acta Histochem 103:423-431
    • (2001) Acta Histochem , vol.103 , pp. 423-431
    • Rezzani, R.1    Rodella, L.2    Biachi, R.3
  • 35
    • 3142604803 scopus 로고    scopus 로고
    • Cyclosporine a and adverse affects on organs: Histochemical studies
    • Rezzani R (2004) Cyclosporine A and adverse affects on organs: histochemical studies. Prog Histochem Cytochem 39:85-128
    • (2004) Prog Histochem Cytochem , vol.39 , pp. 85-128
    • Rezzani, R.1
  • 37
    • 0036667558 scopus 로고    scopus 로고
    • Renal damage mediated by oxidative stress: A hypothesis of protective effects of red wine
    • Rodrigo R, Rivera G (2002) Renal damage mediated by oxidative stress: a hypothesis of protective effects of red wine. Free Radical Biol Med 33:409-422
    • (2002) Free Radical Biol Med , vol.33 , pp. 409-422
    • Rodrigo, R.1    Rivera, G.2
  • 38
    • 0036837322 scopus 로고    scopus 로고
    • Rat kidney antioxidant response to long-term exposure to flavonol rich red wine
    • Rodrigo R, Rivera G, Orellana M, Araya J, Bosco C (2002) Rat kidney antioxidant response to long-term exposure to flavonol rich red wine. Life Sci 71:2881-2895
    • (2002) Life Sci , vol.71 , pp. 2881-2895
    • Rodrigo, R.1    Rivera, G.2    Orellana, M.3    Araya, J.4    Bosco, C.5
  • 39
    • 4544248816 scopus 로고    scopus 로고
    • Amelioration of myoglobinuric renal damage in rats by chronic exposure to flavonol-rich red wine
    • Rodrigo R, Bosco C, Herrera P, Rivera G (2004) Amelioration of myoglobinuric renal damage in rats by chronic exposure to flavonol-rich red wine. Nephrol Dial Transplant 19:2237-2244
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 2237-2244
    • Rodrigo, R.1    Bosco, C.2    Herrera, P.3    Rivera, G.4
  • 40
    • 10044219543 scopus 로고    scopus 로고
    • Diminution of tissue lipid peroxidation in rats is related to the in vitro antioxidant capacity of wine
    • Rodrigo R, Castillo R, Carrasco R, Huerta P, Moreno M (2005) Diminution of tissue lipid peroxidation in rats is related to the in vitro antioxidant capacity of wine. Life Sci 76:889-900
    • (2005) Life Sci , vol.76 , pp. 889-900
    • Rodrigo, R.1    Castillo, R.2    Carrasco, R.3    Huerta, P.4    Moreno, M.5
  • 41
    • 0034808632 scopus 로고    scopus 로고
    • Quercetin, a bioflavonoid, protects against oxidative stress-related renal dysfunction by cyclosporine in rats
    • Satyanarayana PS, Singh D, Chopra K (2001) Quercetin, a bioflavonoid, protects against oxidative stress-related renal dysfunction by cyclosporine in rats. Methods Find Exp Clin Pharmacol 23:175-181
    • (2001) Methods Find Exp Clin Pharmacol , vol.23 , pp. 175-181
    • Satyanarayana, P.S.1    Singh, D.2    Chopra, K.3
  • 42
    • 0345763107 scopus 로고    scopus 로고
    • Inhibitory effect of tea polyphenols on transforming growth factor-β1 expression in rat with cyclosporine A-induced chronic nephrotoxicity
    • Shi SH, Zheng SS, Jia CK, Zhu YF, Xie HY (2004) Inhibitory effect of tea polyphenols on transforming growth factor-β1 expression in rat with cyclosporine A-induced chronic nephrotoxicity. Acta Pharmacol Sin 25:98-103
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 98-103
    • Shi, S.H.1    Zheng, S.S.2    Jia, C.K.3    Zhu, Y.F.4    Xie, H.Y.5
  • 43
    • 0036847274 scopus 로고    scopus 로고
    • Effect of melatonin on the antioxidant enzymes in the kidneys of cyclosporine-treated rats
    • Shin YH, Lee SH, Mun KC (2002) Effect of melatonin on the antioxidant enzymes in the kidneys of cyclosporine-treated rats. Transplant Proc 34:2650-2651
    • (2002) Transplant Proc , vol.34 , pp. 2650-2651
    • Shin, Y.H.1    Lee, S.H.2    Mun, K.C.3
  • 44
    • 0027973602 scopus 로고
    • Possible role of lipid peroxidation in cyclosporine nephrotoxicity in rats
    • Suleymanlar G, Suleymanlar I, Shapiro JI, Chan L (1994) Possible role of lipid peroxidation in cyclosporine nephrotoxicity in rats. Transplant Proc 26:2888-2889
    • (1994) Transplant Proc , vol.26 , pp. 2888-2889
    • Suleymanlar, G.1    Suleymanlar, I.2    Shapiro, J.I.3    Chan, L.4
  • 46
    • 0031814542 scopus 로고    scopus 로고
    • Early induction of transforming growth factor-beta via angiotensin II type 1 receptors contributes to cardiac fibrosis induced by long-term blockade of nitric oxide synthesis in rats
    • Tomita H, Egashira K, Ohara Y, Takemoto M, Koyanagi M, Katoh M, Yamamoto H, et al. (1998) Early induction of transforming growth factor-beta via angiotensin II type 1 receptors contributes to cardiac fibrosis induced by long-term blockade of nitric oxide synthesis in rats. Hypertension 32:273-279
    • (1998) Hypertension , vol.32 , pp. 273-279
    • Tomita, H.1    Egashira, K.2    Ohara, Y.3    Takemoto, M.4    Koyanagi, M.5    Katoh, M.6    Yamamoto, H.7
  • 47
    • 0032769379 scopus 로고    scopus 로고
    • Cellular mechanisms of diabetic vascular hypertrophy
    • Vranes D, Cooper ME, Dilley RJ (1999) Cellular mechanisms of diabetic vascular hypertrophy. Microvasc Res 57:8-18
    • (1999) Microvasc Res , vol.57 , pp. 8-18
    • Vranes, D.1    Cooper, M.E.2    Dilley, R.J.3
  • 48
    • 0028913181 scopus 로고
    • Lipid peroxidation accompanies cyclosporine nephrotoxicity: Effects of vitamin E
    • Wang C, Salahudeen AK (1995) Lipid peroxidation accompanies cyclosporine nephrotoxicity: effects of vitamin E. Kidney Int 47:927-934
    • (1995) Kidney Int , vol.47 , pp. 927-934
    • Wang, C.1    Salahudeen, A.K.2
  • 49
    • 0028821571 scopus 로고
    • Effect of red wine ingestion on the antioxidant capacity of serum
    • Whitehead TP, Robinson D, Allaway S, Syms J, Hale A (1995) Effect of red wine ingestion on the antioxidant capacity of serum. Clin Chem 41:32-35
    • (1995) Clin Chem , vol.41 , pp. 32-35
    • Whitehead, T.P.1    Robinson, D.2    Allaway, S.3    Syms, J.4    Hale, A.5
  • 50
    • 0032807290 scopus 로고    scopus 로고
    • Free-radical-generated F2-isoprostane stimulates cell proliferation and endothelin-1 expression on endothelial cells
    • Yura T, Fukunaga M, Khan R, Nassar GN, Badr KF, Montero A (1999) Free-radical-generated F2-isoprostane stimulates cell proliferation and endothelin-1 expression on endothelial cells. Kidney Int 56:471-478
    • (1999) Kidney Int , vol.56 , pp. 471-478
    • Yura, T.1    Fukunaga, M.2    Khan, R.3    Nassar, G.N.4    Badr, K.F.5    Montero, A.6
  • 51
    • 0035067388 scopus 로고    scopus 로고
    • Viral delivery of Superoxide dismutase gene reduces cyclosporine A-induced nephrotoxicity
    • Zhong Z, Connor HD, Yin M, Wheeler MD, Mason RP, Thurman RG (2001) Viral delivery of Superoxide dismutase gene reduces cyclosporine A-induced nephrotoxicity. Kidney Int 59:1397-1404
    • (2001) Kidney Int , vol.59 , pp. 1397-1404
    • Zhong, Z.1    Connor, H.D.2    Yin, M.3    Wheeler, M.D.4    Mason, R.P.5    Thurman, R.G.6
  • 52
    • 0032964853 scopus 로고    scopus 로고
    • Selective nitration of prostacyclin synthase and defective vasorelaxation in atherosclerotic bovine coronary arteries
    • Zou MH, Leist M, Ullrich V (1999) Selective nitration of prostacyclin synthase and defective vasorelaxation in atherosclerotic bovine coronary arteries. Am J Pathol 154:1359-1365
    • (1999) Am J Pathol , vol.154 , pp. 1359-1365
    • Zou, M.H.1    Leist, M.2    Ullrich, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.