Characterization of in vivo disulfide-reduction mediated drug release in mouse kidneys

Molecular Pharmaceutics

Volumn 9, Issue 2, 2012, Pages 310-317

  Yang, Jun J ^a,c   Kularatne, Sumith A ^a,d   Chen, Xianming ^b   Low, Philip S ^a   Wang, Exing ^b,e  

^a PURDUE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

disulfide reduction; drug release; FRET (F rster resonance energy transfer); intravital microscopy; kidney toxicity; two photon

Indexed keywords

COLCHICINE; DISULFIDE; FOLATE RECEPTOR; FOLIC ACID; RHODAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; COLOR; CONTROLLED STUDY; CYTOSOL; DISULFIDE BOND; DRUG RELEASE; FLUORESCENCE MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; IN VIVO STUDY; KIDNEY; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BORON COMPOUNDS; DISULFIDES; DRUG CARRIERS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; KIDNEY; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, NUDE; OXIDATION-REDUCTION; PROTEIN TRANSPORT; RHODAMINES;

EID: 84863134610     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200483t     Document Type: Article

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