메뉴 건너뛰기




Volumn 287, Issue 8, 2012, Pages 5784-5796

Dimerization and cytoplasmic localization regulate hippo kinase signaling activity in organ size control

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHOSPHORYLATION; BIOLOGICAL FUNCTIONS; CYTOPLASMIC LOCALIZATION; IN-VITRO; KINASE ACTIVITY; KINASE DOMAINS; N-TERMINALS; NUCLEAR EXPORT SIGNALS; NUCLEOCYTOPLASMIC; POINT MUTATIONS; PROLIFERATION AND APOPTOSIS; SIGNALING ACTIVITY; SIGNALING PATHWAYS; SINGLE MUTATION; SIZE CONTROL; STRUCTURAL INFORMATION;

EID: 84863116385     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.310334     Document Type: Article
Times cited : (43)

References (67)
  • 1
    • 0033593316 scopus 로고    scopus 로고
    • Size control in animal development
    • Conlon, I., and Raff, M. (1999) Size control in animal development. Cell 96, 235-244
    • (1999) Cell , vol.96 , pp. 235-244
    • Conlon, I.1    Raff, M.2
  • 2
    • 78650724753 scopus 로고    scopus 로고
    • Hippo signaling. Growth control and beyond
    • Halder, G., and Johnson, R. L. (2011) Hippo signaling. Growth control and beyond. Development 138, 9-22
    • (2011) Development , vol.138 , pp. 9-22
    • Halder, G.1    Johnson, R.L.2
  • 3
    • 77951837150 scopus 로고    scopus 로고
    • The Hippo-YAP pathway in organ size control and tumorigenesis. An updated version
    • Zhao, B., Li, L., Lei, Q., and Guan, K. L. (2010) The Hippo-YAP pathway in organ size control and tumorigenesis. An updated version. Genes Dev. 24, 862-874
    • (2010) Genes Dev. , vol.24 , pp. 862-874
    • Zhao, B.1    Li, L.2    Lei, Q.3    Guan, K.L.4
  • 4
    • 34247191134 scopus 로고    scopus 로고
    • Hippo signaling in organ size control
    • Pan, D. (2007) Hippo signaling in organ size control. Genes Dev. 21, 886-897
    • (2007) Genes Dev. , vol.21 , pp. 886-897
    • Pan, D.1
  • 5
    • 69249117040 scopus 로고    scopus 로고
    • Hippo signaling pathway and organ size control
    • Zhang, L., Yue, T., and Jiang, J. (2009) Hippo signaling pathway and organ size control. Fly 3, 68-73
    • (2009) Fly , vol.3 , pp. 68-73
    • Zhang, L.1    Yue, T.2    Jiang, J.3
  • 6
    • 80054884418 scopus 로고    scopus 로고
    • Hippo signaling. A hub of growth control, tumor suppression, and pluripotency maintenance
    • Yin, M., and Zhang, L. (2011) Hippo signaling. A hub of growth control, tumor suppression, and pluripotency maintenance. J. Genet. Genomics 38, 471-481
    • (2011) J. Genet. Genomics , vol.38 , pp. 471-481
    • Yin, M.1    Zhang, L.2
  • 8
    • 72549090299 scopus 로고    scopus 로고
    • YAP1 is amplified and upregulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
    • Fernandez-L, A., Northcott, P. A., Dalton, J., Fraga, C., Ellison, D., Angers, S., Taylor, M. D., and Kenney, A. M. (2009) YAP1 is amplified and upregulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev. 23, 2729-2741
    • (2009) Genes Dev. , vol.23 , pp. 2729-2741
    • Fernandez-L, A.1    Northcott, P.A.2    Dalton, J.3    Fraga, C.4    Ellison, D.5    Angers, S.6    Taylor, M.D.7    Kenney, A.M.8
  • 10
    • 78651261751 scopus 로고    scopus 로고
    • Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors
    • Sun, G., and Irvine, K. D. (2011) Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors. Dev. Biol. 350, 139-151
    • (2011) Dev. Biol. , vol.350 , pp. 139-151
    • Sun, G.1    Irvine, K.D.2
  • 12
    • 78650471357 scopus 로고    scopus 로고
    • Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways
    • Ren, F., Wang, B., Yue, T., Yun, E. Y., Ip, Y. T., and Jiang, J. (2010) Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc. Natl. Acad. Sci. U.S.A. 107, 21064-21069
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 21064-21069
    • Ren, F.1    Wang, B.2    Yue, T.3    Yun, E.Y.4    Ip, Y.T.5    Jiang, J.6
  • 13
    • 77952954695 scopus 로고    scopus 로고
    • When pathways collide. Collaboration and connivance among signaling proteins in development
    • McNeill, H., and Woodgett, J. R. (2010) When pathways collide. Collaboration and connivance among signaling proteins in development. Nat. Rev. 11, 404-413
    • (2010) Nat. Rev. , vol.11 , pp. 404-413
    • McNeill, H.1    Woodgett, J.R.2
  • 14
    • 77957883342 scopus 로고    scopus 로고
    • The Hippo signaling pathway in development and cancer
    • Pan, D. (2010) The Hippo signaling pathway in development and cancer. Dev. Cell 19, 491-505
    • (2010) Dev. Cell , vol.19 , pp. 491-505
    • Pan, D.1
  • 15
    • 0042733354 scopus 로고    scopus 로고
    • The Drosophila Mst ortholog, Hippo, restricts growth and cell proliferation and promotes apoptosis
    • Harvey, K. F., Pfleger, C. M., and Hariharan, I. K. (2003) The Drosophila Mst ortholog, Hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114, 457-467
    • (2003) Cell , vol.114 , pp. 457-467
    • Harvey, K.F.1    Pfleger, C.M.2    Hariharan, I.K.3
  • 16
    • 0142123293 scopus 로고    scopus 로고
    • The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
    • Jia, J., Zhang, W., Wang, B., Trinko, R., and Jiang, J. (2003) The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis. Genes Dev. 17, 2514-2519
    • (2003) Genes Dev. , vol.17 , pp. 2514-2519
    • Jia, J.1    Zhang, W.2    Wang, B.3    Trinko, R.4    Jiang, J.5
  • 17
    • 14844297327 scopus 로고    scopus 로고
    • Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
    • Lai, Z. C., Wei, X., Shimizu, T., Ramos, E., Rohrbaugh, M., Nikolaidis, N., Ho, L. L., and Li, Y. (2005) Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120, 675-685
    • (2005) Cell , vol.120 , pp. 675-685
    • Lai, Z.C.1    Wei, X.2    Shimizu, T.3    Ramos, E.4    Rohrbaugh, M.5    Nikolaidis, N.6    Ho, L.L.7    Li, Y.8
  • 18
    • 0141505119 scopus 로고    scopus 로고
    • The Salvador partner Hippo promotes apoptosis and cell cycle exit in Drosophila
    • Pantalacci, S., Tapon, N., and Léopold, P. (2003) The Salvador partner Hippo promotes apoptosis and cell cycle exit in Drosophila. Nat. Cell Biol. 5, 921-927
    • (2003) Nat. Cell Biol. , vol.5 , pp. 921-927
    • Pantalacci, S.1    Tapon, N.2    Léopold, P.3
  • 19
    • 0141616617 scopus 로고    scopus 로고
    • Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
    • Udan, R. S., Kango-Singh, M., Nolo, R., Tao, C., and Halder, G. (2003) Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway. Nat. Cell Biol. 5, 914-920
    • (2003) Nat. Cell Biol. , vol.5 , pp. 914-920
    • Udan, R.S.1    Kango-Singh, M.2    Nolo, R.3    Tao, C.4    Halder, G.5
  • 20
    • 0042232429 scopus 로고    scopus 로고
    • Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with Salvador and Warts
    • Wu, S., Huang, J., Dong, J., and Pan, D. (2003) Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with Salvador and Warts. Cell 114, 445-456
    • (2003) Cell , vol.114 , pp. 445-456
    • Wu, S.1    Huang, J.2    Dong, J.3    Pan, D.4
  • 21
    • 40849086201 scopus 로고    scopus 로고
    • SCALLOPED interacts with YORKIE, the nuclear effector of the Hippo tumor suppressor pathway in Drosophila
    • Goulev, Y., Fauny, J. D., Gonzalez-Marti, B., Flagiello, D., Silber, J., and Zider, A. (2008) SCALLOPED interacts with YORKIE, the nuclear effector of the Hippo tumor suppressor pathway in Drosophila. Curr. Biol. 18, 435-441
    • (2008) Curr. Biol. , vol.18 , pp. 435-441
    • Goulev, Y.1    Fauny, J.D.2    Gonzalez-Marti, B.3    Flagiello, D.4    Silber, J.5    Zider, A.6
  • 22
    • 23744458034 scopus 로고    scopus 로고
    • The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP
    • Huang, J., Wu, S., Barrera, J., Matthews, K., and Pan, D. (2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP. Cell 122, 421-434
    • (2005) Cell , vol.122 , pp. 421-434
    • Huang, J.1    Wu, S.2    Barrera, J.3    Matthews, K.4    Pan, D.5
  • 23
    • 42049116586 scopus 로고    scopus 로고
    • The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
    • Wu, S., Liu, Y., Zheng, Y., Dong, J., and Pan, D. (2008) The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev. Cell 14, 388-398
    • (2008) Dev. Cell , vol.14 , pp. 388-398
    • Wu, S.1    Liu, Y.2    Zheng, Y.3    Dong, J.4    Pan, D.5
  • 24
    • 42049120338 scopus 로고    scopus 로고
    • The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
    • Zhang, L., Ren, F., Zhang, Q., Chen, Y., Wang, B., and Jiang, J. (2008) The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev. Cell 14, 377-387
    • (2008) Dev. Cell , vol.14 , pp. 377-387
    • Zhang, L.1    Ren, F.2    Zhang, Q.3    Chen, Y.4    Wang, B.5    Jiang, J.6
  • 25
    • 77957881882 scopus 로고    scopus 로고
    • Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap
    • Neto-Silva, R. M., de Beco, S., and Johnston, L. A. (2010) Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap. Dev. Cell 19, 507-520
    • (2010) Dev. Cell , vol.19 , pp. 507-520
    • Neto-Silva, R.M.1    De Beco, S.2    Johnston, L.A.3
  • 26
    • 78649722171 scopus 로고    scopus 로고
    • Hippo signaling at a glance
    • Zhao, B., Li, L., and Guan, K. L. (2010) Hippo signaling at a glance. J. Cell Sci. 123, 4001-4006
    • (2010) J. Cell Sci. , vol.123 , pp. 4001-4006
    • Zhao, B.1    Li, L.2    Guan, K.L.3
  • 28
    • 0029788972 scopus 로고    scopus 로고
    • The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain
    • Creasy, C. L., Ambrose, D. M., and Chernoff, J. (1996) The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain. J. Biol. Chem. 271, 21049-21053
    • (1996) J. Biol. Chem. , vol.271 , pp. 21049-21053
    • Creasy, C.L.1    Ambrose, D.M.2    Chernoff, J.3
  • 29
    • 0345526420 scopus 로고    scopus 로고
    • A novel interaction motif, SARAH, connects three classes of tumor suppressor
    • Scheel, H., and Hofmann, K. (2003) A novel interaction motif, SARAH, connects three classes of tumor suppressor. Curr. Biol. 13, R899-R900
    • (2003) Curr. Biol. , vol.13
    • Scheel, H.1    Hofmann, K.2
  • 30
    • 70350502865 scopus 로고    scopus 로고
    • Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
    • Zhou, D., Conrad, C., Xia, F., Park, J. S., Payer, B., Yin, Y., Lauwers, G. Y., Thasler, W., Lee, J. T., Avruch, J., and Bardeesy, N. (2009) Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 16, 425-438
    • (2009) Cancer Cell , vol.16 , pp. 425-438
    • Zhou, D.1    Conrad, C.2    Xia, F.3    Park, J.S.4    Payer, B.5    Yin, Y.6    Lauwers, G.Y.7    Thasler, W.8    Lee, J.T.9    Avruch, J.10    Bardeesy, N.11
  • 33
    • 65649126416 scopus 로고    scopus 로고
    • The DeMSTification of mammalian Ste20 kinases
    • Radu, M., and Chernoff, J. (2009) The DeMSTification of mammalian Ste20 kinases. Curr. Biol. 19, R421-R425
    • (2009) Curr. Biol. , vol.19
    • Radu, M.1    Chernoff, J.2
  • 36
    • 0037044808 scopus 로고    scopus 로고
    • Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation
    • Glantschnig, H., Rodan, G. A., and Reszka, A. A. (2002) Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation. J. Biol. Chem. 277, 42987-42996
    • (2002) J. Biol. Chem. , vol.277 , pp. 42987-42996
    • Glantschnig, H.1    Rodan, G.A.2    Reszka, A.A.3
  • 37
    • 0037023722 scopus 로고    scopus 로고
    • Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)
    • Lee, K. K., and Yonehara, S. (2002) Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST). J. Biol. Chem. 277, 12351-12358
    • (2002) J. Biol. Chem. , vol.277 , pp. 12351-12358
    • Lee, K.K.1    Yonehara, S.2
  • 39
    • 33750624298 scopus 로고    scopus 로고
    • The tumor suppressor gene fat controls tissue growth upstream of Expanded in the Hippo signaling pathway
    • Silva, E., Tsatskis, Y., Gardano, L., Tapon, N., and McNeill, H. (2006) The tumor suppressor gene fat controls tissue growth upstream of Expanded in the Hippo signaling pathway. Curr. Biol. 16, 2081-2089
    • (2006) Curr. Biol. , vol.16 , pp. 2081-2089
    • Silva, E.1    Tsatskis, Y.2    Gardano, L.3    Tapon, N.4    McNeill, H.5
  • 40
    • 47749136645 scopus 로고    scopus 로고
    • The tumor suppressor genes dachsous and fat modulate different signaling pathways by regulating dally and dally-like
    • Baena-Lopez, L. A., Rodríguez, I., and Baonza, A. (2008) The tumor suppressor genes dachsous and fat modulate different signaling pathways by regulating dally and dally-like. Proc. Natl. Acad. Sci. U.S.A. 105, 9645-9650
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 9645-9650
    • Baena-Lopez, L.A.1    Rodríguez, I.2    Baonza, A.3
  • 42
    • 34247885980 scopus 로고    scopus 로고
    • Genes affecting cell competition in Drosophila
    • Tyler, D. M., Li, W., Zhuo, N., Pellock, B., and Baker, N. E. (2007) Genes affecting cell competition in Drosophila. Genetics 175, 643-657
    • (2007) Genetics , vol.175 , pp. 643-657
    • Tyler, D.M.1    Li, W.2    Zhuo, N.3    Pellock, B.4    Baker, N.E.5
  • 44
    • 76249109900 scopus 로고    scopus 로고
    • Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
    • Yu, J., Zheng, Y., Dong, J., Klusza, S., Deng, W. M., and Pan, D. (2010) Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev. Cell 18, 288-299
    • (2010) Dev. Cell , vol.18 , pp. 288-299
    • Yu, J.1    Zheng, Y.2    Dong, J.3    Klusza, S.4    Deng, W.M.5    Pan, D.6
  • 45
    • 33750611115 scopus 로고    scopus 로고
    • Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway
    • Bennett, F. C., and Harvey, K. F. (2006) Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr. Biol. 16, 2101-2110
    • (2006) Curr. Biol. , vol.16 , pp. 2101-2110
    • Bennett, F.C.1    Harvey, K.F.2
  • 46
    • 30344445706 scopus 로고    scopus 로고
    • The tumor suppressor genes NF2/Merlin and Expanded act through Hippo signaling to regulate cell proliferation and apoptosis
    • Hamaratoglu, F., Willecke, M., Kango-Singh, M., Nolo, R., Hyun, E., Tao, C., Jafar-Nejad, H., and Halder, G. (2006) The tumor suppressor genes NF2/Merlin and Expanded act through Hippo signaling to regulate cell proliferation and apoptosis. Nat. Cell Biol. 8, 27-36
    • (2006) Nat. Cell Biol. , vol.8 , pp. 27-36
    • Hamaratoglu, F.1    Willecke, M.2    Kango-Singh, M.3    Nolo, R.4    Hyun, E.5    Tao, C.6    Jafar-Nejad, H.7    Halder, G.8
  • 47
    • 33645868635 scopus 로고    scopus 로고
    • The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling
    • Maitra, S., Kulikauskas, R. M., Gavilan, H., and Fehon, R. G. (2006) The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling. Curr. Biol. 16, 702-709
    • (2006) Curr. Biol. , vol.16 , pp. 702-709
    • Maitra, S.1    Kulikauskas, R.M.2    Gavilan, H.3    Fehon, R.G.4
  • 48
    • 33947105009 scopus 로고    scopus 로고
    • The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling
    • Pellock, B. J., Buff, E., White, K., and Hariharan, I. K. (2007) The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling. Dev. Biol. 304, 102-115
    • (2007) Dev. Biol. , vol.304 , pp. 102-115
    • Pellock, B.J.1    Buff, E.2    White, K.3    Hariharan, I.K.4
  • 49
    • 76249125346 scopus 로고    scopus 로고
    • The WW domain protein Kibra acts upstream of Hippo in Drosophila
    • Baumgartner, R., Poernbacher, I., Buser, N., Hafen, E., and Stocker, H. (2010) The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev. Cell 18, 309-316
    • (2010) Dev. Cell , vol.18 , pp. 309-316
    • Baumgartner, R.1    Poernbacher, I.2    Buser, N.3    Hafen, E.4    Stocker, H.5
  • 50
    • 76249093838 scopus 로고    scopus 로고
    • Kibra is a regulator of the Salvador/Warts/Hippo signaling network
    • Genevet, A., Wehr, M. C., Brain, R., Thompson, B. J., and Tapon, N. (2010) Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev. Cell 18, 300-308
    • (2010) Dev. Cell , vol.18 , pp. 300-308
    • Genevet, A.1    Wehr, M.C.2    Brain, R.3    Thompson, B.J.4    Tapon, N.5
  • 51
    • 33845426464 scopus 로고    scopus 로고
    • The Drosophila RASSF homolog antagonizes the hippo pathway
    • Polesello, C., Huelsmann, S., Brown, N. H., and Tapon, N. (2006) The Drosophila RASSF homolog antagonizes the hippo pathway. Curr. Biol. 16, 2459-2465
    • (2006) Curr. Biol. , vol.16 , pp. 2459-2465
    • Polesello, C.1    Huelsmann, S.2    Brown, N.H.3    Tapon, N.4
  • 52
    • 77955988806 scopus 로고    scopus 로고
    • Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling
    • Ribeiro, P. S., Josué, F., Wepf, A., Wehr, M. C., Rinner, O., Kelly, G., Tapon, N., and Gstaiger, M. (2010) Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling. Mol. Cell 39, 521-534
    • (2010) Mol. Cell , vol.39 , pp. 521-534
    • Ribeiro, P.S.1    Josué, F.2    Wepf, A.3    Wehr, M.C.4    Rinner, O.5    Kelly, G.6    Tapon, N.7    Gstaiger, M.8
  • 54
    • 33847660443 scopus 로고    scopus 로고
    • An optimized transgenesis system for Drosophila using germ line-specific phiC31 integrases
    • Bischof, J., Maeda, R. K., Hediger, M., Karch, F., and Basler, K. (2007) An optimized transgenesis system for Drosophila using germ line-specific phiC31 integrases. Proc. Natl. Acad. Sci. U.S.A. 104, 3312-3317
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 3312-3317
    • Bischof, J.1    Maeda, R.K.2    Hediger, M.3    Karch, F.4    Basler, K.5
  • 55
    • 0035341376 scopus 로고    scopus 로고
    • Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development
    • Lee, T., and Luo, L. (2001) Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development. Trends Neurosci. 24, 251-254
    • (2001) Trends Neurosci. , vol.24 , pp. 251-254
    • Lee, T.1    Luo, L.2
  • 60
    • 0031707505 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport. The soluble phase
    • Mattaj, I. W., and Englmeier, L. (1998) Nucleocytoplasmic transport. The soluble phase. Annu. Rev. Biochem. 67, 265-306
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 265-306
    • Mattaj, I.W.1    Englmeier, L.2
  • 61
    • 25444472850 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer (FRET) as a method to calculate the dimerization strength of basic helix-loop-helix (bHLH) proteins
    • Centonze, V. E., Firulli, B. A., and Firulli, A. B. (2004) Fluorescence resonance energy transfer (FRET) as a method to calculate the dimerization strength of basic helix-loop-helix (bHLH) proteins. Biol. Proced. Online 6, 78-82
    • (2004) Biol. Proced. Online , vol.6 , pp. 78-82
    • Centonze, V.E.1    Firulli, B.A.2    Firulli, A.B.3
  • 62
    • 33745997665 scopus 로고    scopus 로고
    • Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage
    • Colombani, J., Polesello, C., Josué, F., and Tapon, N. (2006) Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage. Curr. Biol. 16, 1453-1458
    • (2006) Curr. Biol. , vol.16 , pp. 1453-1458
    • Colombani, J.1    Polesello, C.2    Josué, F.3    Tapon, N.4
  • 63
    • 34247182696 scopus 로고    scopus 로고
    • Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
    • Wei, X., Shimizu, T., and Lai, Z. C. (2007) Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila. EMBO J. 26, 1772-1781
    • (2007) EMBO J. , vol.26 , pp. 1772-1781
    • Wei, X.1    Shimizu, T.2    Lai, Z.C.3
  • 64
    • 3242794878 scopus 로고    scopus 로고
    • Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
    • Praskova, M., Khoklatchev, A., Ortiz-Vega, S., and Avruch, J. (2004) Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras. Biochem. J. 381, 453-462
    • (2004) Biochem. J. , vol.381 , pp. 453-462
    • Praskova, M.1    Khoklatchev, A.2    Ortiz-Vega, S.3    Avruch, J.4
  • 65
    • 33748308721 scopus 로고    scopus 로고
    • Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled coil domains, leads to its stabilization and phosphorylation
    • Callus, B. A., Verhagen, A. M., and Vaux, D. L. (2006) Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled coil domains, leads to its stabilization and phosphorylation. FEBS J. 273, 4264-4276
    • (2006) FEBS J. , vol.273 , pp. 4264-4276
    • Callus, B.A.1    Verhagen, A.M.2    Vaux, D.L.3
  • 66
    • 0035379556 scopus 로고    scopus 로고
    • MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation
    • Lee, K. K., Ohyama, T., Yajima, N., Tsubuki, S., and Yonehara, S. (2001) MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation. J. Biol. Chem. 276, 19276-19285
    • (2001) J. Biol. Chem. , vol.276 , pp. 19276-19285
    • Lee, K.K.1    Ohyama, T.2    Yajima, N.3    Tsubuki, S.4    Yonehara, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.