-
1
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans MJ, Kaufman MH, (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature 292: 154-156.
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
2
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin GR, (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 78: 7634-7638.
-
(1981)
Proc Natl Acad Sci U S A
, vol.78
, pp. 7634-7638
-
-
Martin, G.R.1
-
3
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125: 315-326.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
-
4
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
-
5
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, et al. (2006) Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441: 349-353.
-
(2006)
Nature
, vol.441
, pp. 349-353
-
-
Boyer, L.A.1
Plath, K.2
Zeitlinger, J.3
Brambrink, T.4
Medeiros, L.A.5
-
6
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, et al. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125: 301-313.
-
(2006)
Cell
, vol.125
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
Guenther, M.G.4
Levine, S.S.5
-
7
-
-
73349091835
-
Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance
-
Yamada Y, Aoki H, Kunisada T, Hara A Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance. Cell Stem Cell 6: 10-15.
-
Cell Stem Cell
, vol.6
, pp. 10-15
-
-
Yamada, Y.1
Aoki, H.2
Kunisada, T.3
Hara, A.4
-
8
-
-
0037103988
-
Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells
-
Jirmanova L, Afanassieff M, Gobert-Gosse S, Markossian S, Savatier P, (2002) Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells. Oncogene 21: 5515-5528.
-
(2002)
Oncogene
, vol.21
, pp. 5515-5528
-
-
Jirmanova, L.1
Afanassieff, M.2
Gobert-Gosse, S.3
Markossian, S.4
Savatier, P.5
-
9
-
-
78650972892
-
Calcineurin-NFAT signaling critically regulates early lineage specification in mouse embryonic stem cells and embryos
-
Li X, Zhu L, Yang A, Lin J, Tang F, et al. (2011) Calcineurin-NFAT signaling critically regulates early lineage specification in mouse embryonic stem cells and embryos. Cell Stem Cell 8: 46-58.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 46-58
-
-
Li, X.1
Zhu, L.2
Yang, A.3
Lin, J.4
Tang, F.5
-
10
-
-
0033517123
-
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
-
Matsuda T, Nakamura T, Nakao K, Arai T, Katsuki M, et al. (1999) STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J 18: 4261-4269.
-
(1999)
EMBO J
, vol.18
, pp. 4261-4269
-
-
Matsuda, T.1
Nakamura, T.2
Nakao, K.3
Arai, T.4
Katsuki, M.5
-
11
-
-
0024205842
-
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
-
Williams RL, Hilton DJ, Pease S, Willson TA, Stewart CL, et al. (1988) Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336: 684-687.
-
(1988)
Nature
, vol.336
, pp. 684-687
-
-
Williams, R.L.1
Hilton, D.J.2
Pease, S.3
Willson, T.A.4
Stewart, C.L.5
-
12
-
-
0344845415
-
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
-
Ying QL, Nichols J, Chambers I, Smith A, (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115: 281-292.
-
(2003)
Cell
, vol.115
, pp. 281-292
-
-
Ying, Q.L.1
Nichols, J.2
Chambers, I.3
Smith, A.4
-
13
-
-
77958121543
-
Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling
-
Cha Y, Moon BH, Lee MO, Ahn HJ, Lee HJ, et al. (2010) Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling. Stem Cells 28: 1476-1486.
-
(2010)
Stem Cells
, vol.28
, pp. 1476-1486
-
-
Cha, Y.1
Moon, B.H.2
Lee, M.O.3
Ahn, H.J.4
Lee, H.J.5
-
14
-
-
77957124182
-
SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells
-
Cha Y, Park KS SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells. FEBS Lett 584: 4241-4246.
-
FEBS Lett
, vol.584
, pp. 4241-4246
-
-
Cha, Y.1
Park, K.S.2
-
15
-
-
79951711112
-
Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains
-
Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, et al. (2011) Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell 144: 513-525.
-
(2011)
Cell
, vol.144
, pp. 513-525
-
-
Jiang, H.1
Shukla, A.2
Wang, X.3
Chen, W.Y.4
Bernstein, B.E.5
-
16
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG, (2003) Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784.
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
17
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen X, Xu H, Yuan P, Fang F, Huss M, et al. (2008) Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133: 1106-1117.
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
-
18
-
-
0029879664
-
An RNA polymerase II elongation factor encoded by the human ELL gene
-
Shilatifard A, Lane WS, Jackson KW, Conaway RC, Conaway JW, (1996) An RNA polymerase II elongation factor encoded by the human ELL gene. Science 271: 1873-1876.
-
(1996)
Science
, vol.271
, pp. 1873-1876
-
-
Shilatifard, A.1
Lane, W.S.2
Jackson, K.W.3
Conaway, R.C.4
Conaway, J.W.5
-
19
-
-
0034644734
-
Identification, cloning, expression, and biochemical characterization of the testis-specific RNA polymerase II elongation factor ELL3
-
Miller T, Williams K, Johnstone RW, Shilatifard A, (2000) Identification, cloning, expression, and biochemical characterization of the testis-specific RNA polymerase II elongation factor ELL3. J Biol Chem 275: 32052-32056.
-
(2000)
J Biol Chem
, vol.275
, pp. 32052-32056
-
-
Miller, T.1
Williams, K.2
Johnstone, R.W.3
Shilatifard, A.4
-
20
-
-
0035134284
-
Functional analysis of the leukemia protein ELL: evidence for a role in the regulation of cell growth and survival
-
Johnstone RW, Gerber M, Landewe T, Tollefson A, Wold WS, et al. (2001) Functional analysis of the leukemia protein ELL: evidence for a role in the regulation of cell growth and survival. Mol Cell Biol 21: 1672-1681.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1672-1681
-
-
Johnstone, R.W.1
Gerber, M.2
Landewe, T.3
Tollefson, A.4
Wold, W.S.5
-
21
-
-
0033546189
-
Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53
-
Shinobu N, Maeda T, Aso T, Ito T, Kondo T, et al. (1999) Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53. J Biol Chem 274: 17003-17010.
-
(1999)
J Biol Chem
, vol.274
, pp. 17003-17010
-
-
Shinobu, N.1
Maeda, T.2
Aso, T.3
Ito, T.4
Kondo, T.5
-
22
-
-
17444402393
-
Identification of differential gene expression in germinal vesicle vs. metaphase II mouse oocytes by using annealing control primers
-
Yoon SJ, Chung HM, Cha KY, Kim NH, Lee KA, (2005) Identification of differential gene expression in germinal vesicle vs. metaphase II mouse oocytes by using annealing control primers. Fertil Steril 83: 1293-1296.
-
(2005)
Fertil Steril
, vol.83
, pp. 1293-1296
-
-
Yoon, S.J.1
Chung, H.M.2
Cha, K.Y.3
Kim, N.H.4
Lee, K.A.5
-
23
-
-
38349004471
-
Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin
-
Guo Y, Mantel C, Hromas RA, Broxmeyer HE, (2008) Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells 26: 30-34.
-
(2008)
Stem Cells
, vol.26
, pp. 30-34
-
-
Guo, Y.1
Mantel, C.2
Hromas, R.A.3
Broxmeyer, H.E.4
-
24
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, et al. (2009) The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 11: 1487-1495.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
-
25
-
-
63049101157
-
The role of the ZEB family of transcription factors in development and disease
-
Vandewalle C, Van Roy F, Berx G, (2009) The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci 66: 773-787.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 773-787
-
-
Vandewalle, C.1
van Roy, F.2
Berx, G.3
-
26
-
-
37249030356
-
A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer
-
Gravdal K, Halvorsen OJ, Haukaas SA, Akslen LA, (2007) A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer. Clin Cancer Res 13: 7003-7011.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7003-7011
-
-
Gravdal, K.1
Halvorsen, O.J.2
Haukaas, S.A.3
Akslen, L.A.4
-
27
-
-
78650016651
-
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
-
Tanaka H, Kono E, Tran CP, Miyazaki H, Yamashiro J,et al. Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance. Nat Med 16: 1414-1420.
-
Nat Med
, vol.16
, pp. 1414-1420
-
-
Tanaka, H.1
Kono, E.2
Tran, C.P.3
Miyazaki, H.4
Yamashiro, J.5
-
28
-
-
0037090614
-
Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation
-
Ruchaud S, Korfali N, Villa P, Kottke TJ, Dingwall C, et al. (2002) Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. EMBO J 21: 1967-1977.
-
(2002)
EMBO J
, vol.21
, pp. 1967-1977
-
-
Ruchaud, S.1
Korfali, N.2
Villa, P.3
Kottke, T.J.4
Dingwall, C.5
-
29
-
-
0035831473
-
Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis
-
Slee EA, Adrain C, Martin SJ, (2001) Executioner caspase-3,-6, and-7 perform distinct, non-redundant roles during the demolition phase of apoptosis. J Biol Chem 276: 7320-7326.
-
(2001)
J Biol Chem
, vol.276
, pp. 7320-7326
-
-
Slee, E.A.1
Adrain, C.2
Martin, S.J.3
-
30
-
-
13944273471
-
p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
-
Lin T, Chao C, Saito S, Mazur SJ, Murphy ME, et al. (2005) p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 7: 165-171.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 165-171
-
-
Lin, T.1
Chao, C.2
Saito, S.3
Mazur, S.J.4
Murphy, M.E.5
-
31
-
-
76249102530
-
A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells
-
Lee KH, Li M, Michalowski AM, Zhang X, Liao H, et al. (2010) A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells. Proc Natl Acad Sci U S A 107: 69-74.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 69-74
-
-
Lee, K.H.1
Li, M.2
Michalowski, A.M.3
Zhang, X.4
Liao, H.5
-
32
-
-
0030663519
-
Regulation of ES cell differentiation by functional and conformational modulation of p53
-
Sabapathy K, Klemm M, Jaenisch R, Wagner EF, (1997) Regulation of ES cell differentiation by functional and conformational modulation of p53. EMBO J 16: 6217-6229.
-
(1997)
EMBO J
, vol.16
, pp. 6217-6229
-
-
Sabapathy, K.1
Klemm, M.2
Jaenisch, R.3
Wagner, E.F.4
-
33
-
-
77955052580
-
Regulation of p53 in embryonic stem cells
-
Solozobova V, Blattner C, (2010) Regulation of p53 in embryonic stem cells. Exp Cell Res 316: 2434-2446.
-
(2010)
Exp Cell Res
, vol.316
, pp. 2434-2446
-
-
Solozobova, V.1
Blattner, C.2
-
34
-
-
84855729906
-
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition
-
Kim NH, Kim HS, Li XY, Lee I, Choi HS, et al. (2011) A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. J Cell Biol 195: 417-433.
-
(2011)
J Cell Biol
, vol.195
, pp. 417-433
-
-
Kim, N.H.1
Kim, H.S.2
Li, X.Y.3
Lee, I.4
Choi, H.S.5
|