Metabolomics study on the toxicity of aconite root and its processed products using ultraperformance liquid-chromatography/electrospray-ionization synapt high-definition mass spectrometry coupled with pattern recognition approach and ingenuity pathways analysis

Journal of Proteome Research

Volumn 11, Issue 2, 2012, Pages 1284-1301

  Wang, Xijun ^a   Wang, Huiyu ^a   Zhang, Aihua ^a   Lu, Xin ^a   Sun, Hui ^a   Dong, Hui ^a   Wang, Ping ^a  

^a HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Aconitum carmichaelii Debx; biomarkers; metabolites; metabolomics; pattern recognition analysis; UPLC Q TOF HDMS

Indexed keywords

ACONITUM CARMICHAELII EXTRACT; ANTIINFLAMMATORY AGENT; BIOLOGICAL MARKER; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACONITE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; MALE; METABOLOMICS; MOLECULAR RECOGNITION; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; RAT; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ACONITUM; ANIMALS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; HISTOCYTOCHEMISTRY; MALE; METABOLIC NETWORKS AND PATHWAYS; METABOLOME; METABOLOMICS; MULTIVARIATE ANALYSIS; MYOCARDIUM; PATTERN RECOGNITION, AUTOMATED; PLANT ROOTS; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

ACONITUM; ACONITUM CARMICHAELII;

EID: 84863077686     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200963e     Document Type: Article

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