BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 299, Issue 3, 2010, Pages

  Talati, M ^a   West, J ^a   Blackwell, T R ^a   Loyd, J E ^a   Meyrick, B ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Endothelin receptors A and B; Endothelin 1; Mouse model of heritable pulmonary artery hypertension; Pulmonary artery hypertension

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 2; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN CONVERTING ENZYME; ASPARTIC PROTEINASE; ENDOTHELIN-CONVERTING ENZYME; METALLOPROTEINASE;

ADOLESCENT; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS MACROPHAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PULMONARY HYPERTENSION; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; CONFOCAL MICROSCOPY; GENETICS; MACROPHAGE; METABOLISM; MIDDLE AGED; MOUSE MUTANT; MUTATION; SECRETION; TISSUE DISTRIBUTION;

ADOLESCENT; ADULT; AGED; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; ENDOTHELIN-1; FEMALE; GENE EXPRESSION; HUMANS; HYPERTENSION, PULMONARY; MACROPHAGES; MACROPHAGES, ALVEOLAR; MALE; METALLOENDOPEPTIDASES; MICE; MICE, MUTANT STRAINS; MICROSCOPY, CONFOCAL; MIDDLE AGED; MUTATION; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; TISSUE DISTRIBUTION; YOUNG ADULT;

EID: 77956685602     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00295.2009     Document Type: Article

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