Inducible alkylation of DNA by a quinone methide-peptide nucleic acid conjugate

Biochemistry

Volumn 51, Issue 5, 2012, Pages 1020-1027

  Liu, Yang ^a   Rokita, Steven E ^a  

^a Bldg 142   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROAD APPLICATION; CELLULAR ENVIRONMENT; COLOCALIZE; COMPLEMENTARY SEQUENCES; COVALENT CHEMISTRY; HIGH SELECTIVITY; PEPTIDE NUCLEIC ACID; QUINONE METHIDE; SINGLE-STRANDED REGION; SITE-SPECIFIC; TEMPLATE STRAND;

ALKYLATION; ASSOCIATION REACTIONS; OLIGONUCLEOTIDES; PEPTIDES; REACTION INTERMEDIATES; REACTION KINETICS; THERMODYNAMICS;

NUCLEIC ACIDS;

DOUBLE STRANDED DNA; PEPTIDE NUCLEIC ACID; QUINONE DERIVATIVE; QUINONE METHIDE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; DNA ALKYLATION; DNA SEQUENCE; DNA STRAND; DNA TEMPLATE; GENE TARGETING; PRIORITY JOURNAL;

ALKYLATION; DNA; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HYDROLYSIS; INDOLEQUINONES; NUCLEIC ACID HETERODUPLEXES; OXIDATION-REDUCTION; PEPTIDE NUCLEIC ACIDS; THERMODYNAMICS;

EID: 84863018655     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201492b     Document Type: Article

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