Rapid and efficient hybridization-triggered crosslinking within a DNA duplex by an oligodeoxyribonucleotide bearing a conjugated cyclopropapyrroloindole

Nucleic Acids Research

Volumn 24, Issue 4, 1996, Pages 683-687

  Lukhtanov, Eugeny A ^a   Podyminogin, Mikhail A ^a   Kutyavin, Igor V ^a   Meyer Jr , Rich B ^a   Gamper, Howard B ^a  

^a Epoch Pharmaceutical Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; COMPLEMENTARY DNA; CYCLOPROPAPYRROLOINDOLE; DOUBLE STRANDED DNA; OLIGODEOXYRIBONUCLEOTIDE; PROTEIN SUBUNIT; RACHELMYCIN; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DNA ALKYLATION; DNA CROSS LINKING; DNA HYBRIDIZATION; DNA REPLICATION; DRUG CONJUGATION; DRUG DNA BINDING; DRUG STABILITY; DRUG SYNTHESIS; PRIORITY JOURNAL; TRANSCRIPTION INITIATION;

ALKYLATION; BASE SEQUENCE; CROSS-LINKING REAGENTS; DNA; INDOLES; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES;

EID: 0029870591     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/24.4.683     Document Type: Article

References (33)

1. Webb, T.R. and Matteucci, M.D. (1986) J. Am. Chem. Soc., 108, 2764-2765.
2. Webb, T.R. and Matteucci, M.D (1986) Nucleic Acids Res., 19, 7661-7674.
3. Shaw, J.-P., Milligan, J.F., Krawczyk, S.H., and Matteucci, M. (1991) J. Am. Chem. Soc., 113, 7765-7766.
4. Li, T., Zeng, Q., and Rokita, S.E. (1994) Bioconjugate Chem., 5, 497-500.
5. Knorre, D.G. and Vlassov, V.V. (1985) Prog. Nucleic Acids Res. Mol. Biol., 32, 291-320.
6. Kutyavin, I.V., Gamper, H.B., Gall, A.A., and Meyer, R.B. (1993) J. Am. Chem. Soc., 115, 9303-9304.
7. Podyminogin, M.A., Meyer, R.B., and Camper, H.B. (1995) Biochemistry 34, 13098-13108.
8. Tabone, J.C, Stamm, M.R., Gamper, H.B., and Meyer, R.B. (1994) Biochemistry, 33, 375-383.
9. Povsic, T.J. and Dervan, P.B. (1990) J. Am. Chem. Soc., 112, 9428-9430.
10. Vlassov, V.V., Gorn, V.V., Ivanova, E.M., Kazakov, S.A., and Mamaev, S.V. (1983) FEBS Lett., 162, 286-289.
11. Gruff, E.S. and Orgel, L.E. (1991) Nucleic Acids Res., 19, 6849-6854.
12. Summerton, J. and Bartlett, P.A. (1978) J. Mol. Biol., 122, 145-162.
13. Iverson, B.L. and Dervan, P.B. (1987) J. Am. Chem. Soc., 109, 1241-1243.
14. Li, T. and Rokita, S.E. (1991) J. Am. Chem. Soc., 113, 7771-7773.
15. Gamper, H.B., Cimino, G.D., and Hearst, J.E. (1987) J. Mol. Biol., 197, 349-362.
16. Takasugi, M., Guendouz, A., Chassignol, M., Decout, J.L., Lhomme, J., Thuong, N.T., and Helene, C. (1991) Proc. Natl. Acad. Sci. USA, 88, 5402-5606.
17. Reynolds, V.L., McGovren, J.P., and Hurley, L.H. (1986) J. Antibiotics (Tokyo), 39, 319-334.
18. Boger, D.L. and Johnson, D.S. (1995) Proc. Natl. Acad. Sci. USA, 92, 3642-3649.
19. Hurley, L.H., Reynolds, L.L., Swenson, D.H., and Scahill, T. (1984) Science, 226, 843-844.
20. Warpehoski, M.A., Gebhard, I., Kelly, R.C, Knieger, W.C., Li, L.H, McGovren, J.P., Prairie, M.D., Wicnienski, N., Wierenga, W. (1988) J. Med. Chem., 31, 590-603.
21. Warpehoski, M.A. and Hurley, L.H. (1988) Chem. Res. Toxicol., 1, 315-333.
22. Lin, C.H., Beale, J.M., and Hurley, L.H. (1991) Biochemistry, 30, 3597-3602.
23. Reynolds, V.L, Molineux, I J., Kaplan, D.J., Swenson, D.H., and Hurley, L.H. (1985) Biochemistry, 24, 6628-6237.
24. Hurley, L.H., Warpehoski, M.A., Lee, C.-S, McGovern, J.P., Scahill, T.A., Kelly, R.C, Mitchell, M.A., Wicnienski, N.A., Gebhard, I., Johnson, P.D., and Bradford, V.S. (1990) J. Am. Chem. Soc., 112, 4633-4649.
25. Boger, D.L., Johnson, D.S., Yun, W., and Tarby, C.M. (1994) Bioorg. Med. Chem., 2, 115-135.
26. Kelly, R.C., Gebhard, I., Wicnienski, N., Aristoff, P A., Johnson, P.D., and Martin, D.G. (1987) J. Am. Chem. Soc., 109, 6837-6838.
27. Sugiyama, H., Fujiwara, T., Ura, A., Tashiro, T., Yamamoto, K., Kawanishi, S., and Saito, I. (1994) Chem. Res. Toxicol., 7, 673-683.
28. Maxam, A.M. and Gilbert, W. (1977) Proc. Natl. Acad. Sci. USA, 74, 560-564.
29. Boger, D L. and Palanki, M.S.S. (1992) J. Am. Chem. Soc., 114, 9318-9327, and references cited therein.
30. Silverman, R. B. (1988) Mechanism-Based Enzyme Inactivation: Chemistry and Enzymology. CRC Press: Boca Raton, FL.
31. Lin, C.H., Sun, D., and Hurley, L.H. (1991) Chem. Res. Toxicol., 4, 21-26.
32. Perrin, D.M., Mazumder, A., Sadeghi, F., and Sigman, D.S. (1994) Biochemistry, 33, 3848-3854.
33. Helene, C. (1991) Anti-Cancer Drug Des., 6, 569-584.