The alkyl-connected 2-amino-6-vinylpurine (AVP) crosslinking agent for improved selectivity to the cytosine base in RNA

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 8, 2010, Pages 2894-2901

  Taniguchi, Yosuke ^a,c   Kurose, Yusuke ^a   Nishioka, Takamasa ^a   Nagatsugi, Fumi ^b,c   Sasaki, Shigeki ^a,c  

^a KYUSHU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Antisense oligonucleotide; Base selectivity; Crosslink; RNA

Indexed keywords

1' BETA CYANO 2' DEOXYRIBOSE; 2 AMINO 6 VINYLPURINE NUCLEOSIDE DERIVATIVE; ALKYL GROUP; ANTISENSE OLIGONUCLEOTIDE; BUTANEDIOL; CARBENE; CARBOHYDRATE DERIVATIVE; COMPLEMENTARY DNA; COMPLEMENTARY RNA; CYTOSINE; DOUBLE STRANDED DNA; ETHYLENE; LUCIFERASE; MESSENGER RNA; NITRILE; PURINE DERIVATIVE; RNA; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

ALKYLATION; ARTICLE; CIRCULAR DICHROISM; DNA CONFORMATION; DNA CROSS LINKING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DENATURATION; RNA STRUCTURE; SYNTHESIS; THERMOSTABILITY;

BASE SEQUENCE; CROSS-LINKING REAGENTS; CYTOSINE; OLIGONUCLEOTIDES, ANTISENSE; PURINES; RNA; VINYL COMPOUNDS;

EID: 77950517274     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.03.008     Document Type: Article

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