-
1
-
-
84974993880
-
Platinum complexes for the treatment of cancer
-
Rosenberg, B. et al. (1978) Platinum complexes for the treatment of cancer. Interdiscip. Sci. Rev., 3, 134-147.
-
(1978)
Interdiscip. Sci. Rev.
, vol.3
, pp. 134-147
-
-
Rosenberg, B.1
-
2
-
-
0345256652
-
Cisplatin: mode of cytotoxic action and molecular basis of resistence
-
Siddk, Z. H. (2003) Cisplatin: mode of cytotoxic action and molecular basis of resistence. Oncogene, 22, 7265-7279.
-
(2003)
Oncogene
, vol.22
, pp. 7265-7279
-
-
Siddk, Z.H.1
-
3
-
-
18244379333
-
Cellular processing of platinum anticancer drugs
-
Wang, D. et al. (2005) Cellular processing of platinum anticancer drugs. Nat. Rev., 4, 307-319.
-
(2005)
Nat. Rev.
, vol.4
, pp. 307-319
-
-
Wang, D.1
-
4
-
-
0030850593
-
Cisplatin-DNA adduct determination in the hepatic albumin gene as compared to whole genomic DNA
-
Zhang, Z. et al. (1997) Cisplatin-DNA adduct determination in the hepatic albumin gene as compared to whole genomic DNA. Chem. Res. Toxicol., 10, 971-977.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 971-977
-
-
Zhang, Z.1
-
5
-
-
66049128092
-
Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway
-
Jiang, M. et al. (2009) Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway. Am. J. Physiol. Renal Physiol., 296, 983-993.
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.296
, pp. 983-993
-
-
Jiang, M.1
-
6
-
-
67449088495
-
Proteomics and pathway analysis identifies JNK signaling as critical for high linear energy transfer radiation-induced apoptosis in non-small lung cancer cells
-
Ståhl, S. et al. (2009) Proteomics and pathway analysis identifies JNK signaling as critical for high linear energy transfer radiation-induced apoptosis in non-small lung cancer cells. Mol. Cell. Proteomics, 8, 1117-1129.
-
(2009)
Mol. Cell. Proteomics
, vol.8
, pp. 1117-1129
-
-
Ståhl, S.1
-
7
-
-
0034306332
-
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1
-
Melchionna, R. et al. (2000) Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1. Nat. Cell Biol., 2, 762-765.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 762-765
-
-
Melchionna, R.1
-
8
-
-
33344476097
-
DNA damage checkpoints in mammals
-
Niida, H. et al. (2006) DNA damage checkpoints in mammals. Mutagenesis, 21, 3-9.
-
(2006)
Mutagenesis
, vol.21
, pp. 3-9
-
-
Niida, H.1
-
9
-
-
44249118962
-
ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis
-
Pabla, N. et al. (2008) ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. J. Biol. Chem., 283, 6572-6583.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 6572-6583
-
-
Pabla, N.1
-
10
-
-
0001479498
-
A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily
-
Hazel, T. G. et al. (1988) A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily. Proc. Natl Acad. Sci. USA, 85, 8444-8448.
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 8444-8448
-
-
Hazel, T.G.1
-
11
-
-
0242637365
-
Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells
-
Kolluri, S. K. et al. (2003) Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells. Mol. Cell. Biol., 23, 8651-8667.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8651-8667
-
-
Kolluri, S.K.1
-
12
-
-
10944245500
-
RXR acts as a carrier for TR3 nuclear export in a 9-cis retinoic acid-dependent manner in gastric cancer cells
-
Lin, X. F. et al. (2004) RXR acts as a carrier for TR3 nuclear export in a 9-cis retinoic acid-dependent manner in gastric cancer cells. J. Cell Sci., 117, 5609-5621.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 5609-5621
-
-
Lin, X.F.1
-
13
-
-
0034682890
-
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
-
Li, H. et al. (2000) Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. Science, 289, 1159-1164.
-
(2000)
Science
, vol.289
, pp. 1159-1164
-
-
Li, H.1
-
14
-
-
0028842908
-
Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis
-
Woronicz, J. D. et al. (1995) Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis. Mol. Cell. Biol., 15, 6364-6376.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6364-6376
-
-
Woronicz, J.D.1
-
15
-
-
0030977267
-
Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis
-
Cheng, L. E. C. et al. (1997) Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. EMBO J., 16, 1865-1875.
-
(1997)
EMBO J
, vol.16
, pp. 1865-1875
-
-
Cheng, L.E.C.1
-
16
-
-
77951722800
-
A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro
-
Liu, J. J. et al. (2010) A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro. Cancer Res., 70, 3628-3637.
-
(2010)
Cancer Res
, vol.70
, pp. 3628-3637
-
-
Liu, J.J.1
-
17
-
-
0027223906
-
Functional domains and phosphorylation of the orphan receptor Nur77
-
Davis, I. J. et al. (1993) Functional domains and phosphorylation of the orphan receptor Nur77. Mol. Endocrinol., 7, 953-964.
-
(1993)
Mol. Endocrinol.
, vol.7
, pp. 953-964
-
-
Davis, I.J.1
-
18
-
-
33845872610
-
Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation
-
Liu, B. et al. (2007) Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation. Endocrinology, 148, 34-44.
-
(2007)
Endocrinology
, vol.148
, pp. 34-44
-
-
Liu, B.1
-
19
-
-
0033780029
-
Modulation of retinoid signalling through NGFinduced nuclear export of NGFI-B
-
Katagiri, Y. et al. (2000) Modulation of retinoid signalling through NGFinduced nuclear export of NGFI-B. Nat. Cell Biol., 2, 435-440.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 435-440
-
-
Katagiri, Y.1
-
20
-
-
0035980060
-
Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis
-
Masuyama, N. et al. (2001) Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis. J. Biol. Chem., 276, 32799-32805.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32799-32805
-
-
Masuyama, N.1
-
21
-
-
0035957428
-
Akt phosphorylates and regulates the orphan nuclear receptor Nur77
-
Pekarsky, Y. et al. (2001) Akt phosphorylates and regulates the orphan nuclear receptor Nur77. Proc. Natl Acad. Sci. USA, 27, 3690-3694.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.27
, pp. 3690-3694
-
-
Pekarsky, Y.1
-
22
-
-
56049110835
-
Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria
-
Chen, H. Z. et al. (2008) Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria. Carcinogenesis, 2078-2088.
-
(2008)
Carcinogenesis
, pp. 2078-2088
-
-
Chen, H.Z.1
-
23
-
-
10744220096
-
The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation
-
Rosenhagen, M. C. et al. (2003) The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation. Mol. Endocrinol., 17, 1991-2001.
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1991-2001
-
-
Rosenhagen, M.C.1
-
24
-
-
17844366538
-
The pregnane X receptor regulates gene expression in a ligand- and promoter- selective fashion
-
Masuyama, H. et al. (2005) The pregnane X receptor regulates gene expression in a ligand- and promoter- selective fashion. Mol. Endocrinol., 19, 1170-1180.
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 1170-1180
-
-
Masuyama, H.1
-
25
-
-
33845699109
-
p53 mediates the negative regulation of MDM2 by orphan receptor TR3
-
Zhao, B. X. et al. (2006) p53 mediates the negative regulation of MDM2 by orphan receptor TR3. EMBO J., 25, 5703-5715.
-
(2006)
EMBO J
, vol.25
, pp. 5703-5715
-
-
Zhao, B.X.1
-
26
-
-
75149160568
-
Inhibitors of histone deacetylases suppress cisplatininduced p53 activation and apoptosis in renal tubular cells
-
Dong, G. et al. (2010) Inhibitors of histone deacetylases suppress cisplatininduced p53 activation and apoptosis in renal tubular cells. Am. J. Physiol. Renal Physiol., 298, 293-300.
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.298
, pp. 293-300
-
-
Dong, G.1
-
27
-
-
77950819843
-
Role of epidermal growth factor receptor degradation in cisplatin-induced cytotoxicity in head and neck cancer
-
Ahsan, A. et al. (2010) Role of epidermal growth factor receptor degradation in cisplatin-induced cytotoxicity in head and neck cancer. Cancer Res., 70, 2862-2869.
-
(2010)
Cancer Res
, vol.70
, pp. 2862-2869
-
-
Ahsan, A.1
-
28
-
-
0037073737
-
Checkpoint kinase 2 (Chk2) monomers or dimers phosphorylate Cdc25C after DNA damage regardless of threonine 68 phosphorylation
-
Ahn, J. et al. (2002) Checkpoint kinase 2 (Chk2) monomers or dimers phosphorylate Cdc25C after DNA damage regardless of threonine 68 phosphorylation. J. Biol. Chem., 277, 48418-48426.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48418-48426
-
-
Ahn, J.1
-
29
-
-
0037795780
-
Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation
-
Schwarz, J. K. et al. (2003) Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation. Mol. Cancer Res., 1, 598-609.
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 598-609
-
-
Schwarz, J.K.1
-
30
-
-
9944262729
-
A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway
-
Li, Q. et al. (2004) A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway. J. Biol. Chem., 279, 52106-52116.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52106-52116
-
-
Li, Q.1
-
31
-
-
39749096628
-
BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma
-
Chan, B. C. et al. (2008) BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma. Oncogene, 27, 1208-1217.
-
(2008)
Oncogene
, vol.27
, pp. 1208-1217
-
-
Chan, B.C.1
-
32
-
-
0032932201
-
SAG, a novel zinc RING finger protein that Protects cells fromapoptosis induced by redox agents
-
Duan, H. et al. (1999) SAG, a novel zinc RING finger protein that Protects cells fromapoptosis induced by redox agents. Mol. Cell. Biol., 19, 3145-3155.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3145-3155
-
-
Duan, H.1
-
33
-
-
0030014643
-
Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO 1 and staurosporine induced cell death
-
Mehlen, P. et al. (1996) Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO 1 and staurosporine induced cell death. J. Biol. Chem., 271, 16510-16514.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16510-16514
-
-
Mehlen, P.1
-
34
-
-
0034053147
-
Chemoprevention of familial adenomatous polyposis development in the APCmin mouse model by 1, 4-phenylene bis(methylene)-selenocyanate
-
Rao, C. V. et al. (2000) Chemoprevention of familial adenomatous polyposis development in the APCmin mouse model by 1,4-phenylene bis(methylene)-selenocyanate. Carcinogenesis, 21, 617-621.
-
(2000)
Carcinogenesis
, vol.21
, pp. 617-621
-
-
Rao, C.V.1
-
35
-
-
84859603974
-
The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling
-
doi:10. 1136/gutjnl-2011-300783
-
Chen, H. Z. et al. (2011) The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling. Gut doi:10. 1136/gutjnl-2011-300783.
-
(2011)
Gut
-
-
Chen, H.Z.1
-
36
-
-
34548248638
-
Nuclear orphan receptor TR3/Nur77 mediates melanoma cell apoptosis
-
Yu, H. et al. (2007) Nuclear orphan receptor TR3/Nur77 mediates melanoma cell apoptosis. Cancer Biol. Ther., 6, 405-412.
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 405-412
-
-
Yu, H.1
-
37
-
-
0037057320
-
Modulation of PI3K/Akt pathway by E1a mediates sensitivity to cisplatin
-
Viniegra, J. G. et al. (2002) Modulation of PI3K/Akt pathway by E1a mediates sensitivity to cisplatin. Oncogene, 21, 7131-7136.
-
(2002)
Oncogene
, vol.21
, pp. 7131-7136
-
-
Viniegra, J.G.1
-
38
-
-
0037013243
-
Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach
-
O'Neill, T. et al. (2002) Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach. J. Biol. Chem., 277, 16102-16115.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16102-16115
-
-
O'Neill, T.1
-
39
-
-
0034142034
-
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
-
Shieh, S. Y. et al. (2000) The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev., 14, 289.
-
(2000)
Genes Dev
, vol.14
, pp. 289
-
-
Shieh, S.Y.1
-
40
-
-
63349098780
-
A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3
-
Lei, N. et al. (2009) A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3. Nucleic Acids Res., 37, 832-848.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 832-848
-
-
Lei, N.1
-
41
-
-
78651376455
-
Regulation of Nur77 expression by b-catenin and its mitogenic effect in colon cancer cells
-
Wu, H. et al. (2011) Regulation of Nur77 expression by b-catenin and its mitogenic effect in colon cancer cells. FASEB J., 25, 192-205.
-
(2011)
FASEB J
, vol.25
, pp. 192-205
-
-
Wu, H.1
-
42
-
-
0035135599
-
Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis
-
Qiao, D. et al. (2001) Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis. Carcinogenesis, 22, 35-41.
-
(2001)
Carcinogenesis
, vol.22
, pp. 35-41
-
-
Qiao, D.1
-
43
-
-
84861997104
-
Prolyl isomerase Pin1 stabilizes and activates orphan nuclear receptor TR3 to promote mitogenesis
-
doi:10.1038/onc.2011.463
-
Chen, H. Z. et al. (2011) Prolyl isomerase Pin1 stabilizes and activates orphan nuclear receptor TR3 to promote mitogenesis. Oncogene, doi:10.1038/onc. 2011. 463
-
(2011)
Oncogene
-
-
Chen, H.Z.1
-
44
-
-
33744917052
-
Orphan nuclear receptor Nur77 induces zinc finger protein GIOT-1 gene expression, and GIOT-1 acts as a novel corepressor of orphan nuclear receptor SF-1 via recruitment of HDAC2
-
Song, K. H. et al. (2006) Orphan nuclear receptor Nur77 induces zinc finger protein GIOT-1 gene expression, and GIOT-1 acts as a novel corepressor of orphan nuclear receptor SF-1 via recruitment of HDAC2. J. Biol. Chem., 281, 15605-15614.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15605-15614
-
-
Song, K.H.1
-
45
-
-
33748763554
-
Identification of nerve growth factor-responsive element of the TCL1 promoter as a novel negative regulatory element
-
Hiromura, M. et al. (2006) Identification of nerve growth factor-responsive element of the TCL1 promoter as a novel negative regulatory element. J. Biol. Chem., 281, 27753-27764.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 27753-27764
-
-
Hiromura, M.1
-
46
-
-
54049103066
-
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
-
Fernández de Mattos, S. et al. (2008) FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells. Mol. Cancer Ther., 7, 3237-3246.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 3237-3246
-
-
Fernández de Mattos, S.1
-
47
-
-
0141705418
-
TR3/Nur77 in colon cancer cell apoptosis
-
Andrew, J. W. et al. (2003) TR3/Nur77 in colon cancer cell apoptosis. Cancer Res., 63, 5401-5407.
-
(2003)
Cancer Res
, vol.63
, pp. 5401-5407
-
-
Andrew, J.W.1
|