A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro

Cancer Research

Volumn 70, Issue 9, 2010, Pages 3628-3637

  Liu, Jing Jing ^a   Zeng, Hui Ni ^a   Zhang, Lian Ru ^a   Zhan, Yan Yan ^a   Chen, Yan ^a   Wang, Yuan ^a   Wang, Juan ^a   Xiang, Shao Hua ^a   Liu, Wen Jun ^a   Wang, Wei Jia ^a   Chen, Hang Zi ^a   Shen, Yue Mao ^a   Su, Wen Jin ^a   Huang, Pei Qiang ^a   Zhang, Hong Kui ^a   Wu, Qiao ^a,b  

^a XIAMEN UNIVERSITY   (China)

^b Key Laboratory for Chemical Biology of Fujian Province   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(3,5 DIHYDROXY)PHENYL] 1 OCTANOL; 1 [(3,5-DIHYDROXY)PHENYL]OCTAN 1 ONE; AMYL 2 [3,4 DIHYDROXY 2 (1 NONANOYL)PHENYL]ACETATE; AMYL 2 [3,5 DIHYDROXY 2 (1 NONANOYL)PHENYL]ACETATE; BENZENE; CYTOSPORONE B; DRUG ANALOG; ESTER; ETHYL 2 [(3,5 DIHYDROXY)PHENYL]ACETATE; ETHYL 2 [3 ACETAMINO 2 (OCTANOYL)PHENYL]ACETATE; ETHYL 2 [3 HYDROXY 2 (OCTANOYL)PHENYL]ACETATE; ETHYL 2 [3,5 DIHYDROXY 2 (1 DECANOYL)PHENYL]ACETATE; ETHYL 2 [3,5 DIHYDROXY 2 (1 NONANOYL)PHENYL]ACETATE; ETHYL 2 [3,5 DIHYDROXY 2 (1 OCTANOYL)PHENYL]ACETATE; ETHYL 2 [3,5 DIHYDROXY 2 (1 UNDECANOYL)PHENYL]ACETATE; ETHYL 2 [4 HYDROXY 2 (NONANOYL)PHENYL]ACETATE; NATURAL PRODUCT; NUCLEAR RECEPTOR NUR77; PHENOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRION; MOUSE; MULTIPLE CYCLE TREATMENT; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ANALYSIS; TRANSACTIVATION;

ANIMALS; APOPTOSIS; DRUG DELIVERY SYSTEMS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, NUDE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NERVE TISSUE PROTEINS; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; PHENYLACETATES; STOMACH NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77951722800     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-3160     Document Type: Article

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