Tubeimoside-1 induces G2/M phase arrest and apoptosis in SKOV-3 cells through increase of intracellular Ca 2+and caspase-dependent signaling pathways

International Journal of Oncology

Volumn 40, Issue 2, 2012, Pages 535-543

  Chen, Wen Juan ^a   Yu, Chao ^a   Yang, Zhu ^a   He, Jun Lin ^a   Yin, Juan ^a   Liu, Hai Zhong ^a   Liu, Hong Tao ^a   Wang, Ying Xiong ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Mitochondrial dysfunction; SKOV 3 cells; Tubeimoside 1

Indexed keywords

CASPASE 3; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HERBACEOUS AGENT; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2; TUBEIMOSIDE 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CANCER PREVENTION; CANCER THERAPY; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM SIGNALING; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUGS, CHINESE HERBAL; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; OLIGOPEPTIDES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SAPONINS; TRANSCRIPTION FACTOR CHOP; TRITERPENES;

EID: 84862947477     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1218     Document Type: Article

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