A new Phaseolus vulgaris lectin induces selective toxicity on human liver carcinoma Hep G2 cells

Archives of Toxicology

Volumn 85, Issue 12, 2011, Pages 1551-1563

  Fang, Evandro Fei ^a   Pan, Wen Liang ^a   Wong, Jack Ho ^a   Chan, Yau Sang ^a   Ye, Xiu Juan ^a   Ng, Tzi Bun ^a,b  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Cytokine; Lectin; Liver cancer; Nitric oxide

Indexed keywords

GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 2; MESSENGER RNA; NITRIC OXIDE; PLANT LECTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL STRAIN HEPG2; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG ISOLATION; DRUG MECHANISM; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHASEOLUS VULGARIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; CYTOKINES; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; HEP G2 CELLS; HUMANS; LECTINS; LIVER NEOPLASMS; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; NITRIC OXIDE; PHASEOLUS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

ORYCTOLAGUS CUNICULUS; PHASEOLUS VULGARIS; RATTUS; TIRUMALA;

EID: 82355187576     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0698-x     Document Type: Article

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